ABX: Summer Meeting
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    Eden Project, Bodelva, St Austell, Cornwall, PL24 2SG

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Programme

Thursday 11th July

11:30 - 12:00 Arrival and registration

12:00 - 12:30 Overview of ABX and buffet lunch

12:30 - 12:40 Antimicrobial Peptides
Professor Mat Upton – University of Plymouth

12:40 - 12:50 Extreme Antimicrobial Discovery
Dr Garry Farnham – University of Plymouth

12:50 - 13:00 Good drugs for bad bugs: Finding new antibiotics for tuberculosis
Dr Jonathan Cox – University of Aston

13:00 - 13:10 DNA topoisomerases as targets for antibacterial chemotherapy
Professor Tony Maxwell - John Innes Centre Norfolk

13:10 - 13:20 Bioprospecting for novel, natural product-based antibiotics from deep-sea sponges
Dr Catherine Back – University of Bristol

13:20 - 13:30 Metagenomic sample selection: A guided approach to Natural product discovery?
Sam Williams – University of Bristol

13:30 - 13:40 DNA Quadruplexes in Antimicrobial Resistance Gene Regulation
Dr Christopher O'Kane – Anglia Ruskin University

13:40 - 13:50 Integrative structural biology of tripartite efflux-pumps and the cell envelope in Gram-negative bacteria
Dr Vassiliy Bavro

13:50 - 14:00 Simulation-guided de novo design of antimicrobial peptides
Dr Martin Ulmschneider – King’s College London

14:00 - 14:20 Break

14:20 - 14:30 Understanding mechanisms of antibiotic toxicity and searching for new antimicrobials
Dr Mark Shepherd – University of Kent

14:30 - 14:40 Biologics Drug Discovery in Infectious Diseases
Dr Soumya Palliyil – University of Aberdeen

14:40 - 14:50 Green pharmacy in antibiotic development – prolonging efficacy by prioritising compounds least likely to select for resistance
Dr Aimee Murray – University of Exeter

14:50 - 15:00 Interference with the E. faecalis pCF10 pheromone responsive plasmid system
Amy Sterling – Ulster University

15:00 - 15:10 Cell-free synthetic biology for natural products
Dr Simon Moore – University of Kent

15:10 - 15:20 Cross-resistance and collateral sensitivity between clinical antibiotics and natural antimicrobials: the case of Cornish seaweeds
Michiel Vos – University of Exeter

15:20 - 15:30 Promoting the Antarctic as an ecosystem for antibiotic discovery
Professor Melody Clark – British Antarctic Survey

15:30 - 15:40 Integrating interdisciplinary approaches to tackle antibiotic resistance in tuberculosis (TB)
Professor Sanjib Bhakta – University of London

15:40 - 16:00 Old drugs learn new tricks: drug repurposing as a strategy to uncover effective antibacterials
Dr Marta Martins – University of Dublin

16:00 - 16:10 Boolean modelling of Pseudomonas aeruginosa virulence and quorum sensing networks
Dr Marie Lisandra Zepeda Mendoza – University of Birmingham

16:10 - 16:20 Summary of first day- focus for tomorrow

16:20 - 18:00 Breakout at Eden Project - closes at 18:00

18:00 Transport to hotel

19:30 Evening meal at Carlyon Bay Hotel


Friday 12 July

09:00 - 10:30 Smaller discussion in 3 or 4 groups. Example topic ideas: natural/ products/ synthetic/ chemical. Bottlenecks/ issues.

10:30 - 11:00 Break

11:00 - 13:00 Round table meeting – addressing bottlenecks. How to take ABX further. Potential soil sample provided by the Eden Project for all attendees to work on using their expertise. Consolidate expertise information for registry. Talk about second meeting.

13:00 Finish

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