Antibiotic resistant pathogens research group publications

Articles 2016 - present

  • Butler J, Kelly SD, Muddiman KJ, Besinis A & Upton M 2022 'Hospital sink traps as a potential source of the emerging multidrug-resistant pathogen Cupriavidus pauculus: characterization and draft genome sequence of strain MF1' Journal of Medical Microbiology 71, (2) , DOI Open access
  • Powell N, Kohl D, Ahmed S, Kent B, Sandoe J, Tonkin-Crine S, Owens R, Stephens J & Upton M 2022 'Effectiveness of interventions that support penicillin allergy assessment and de-labeling of patients by non-allergy specialists: a systematic review protocol' JBI Evidence Synthesis 20, (2) 624-632 , DOI Open access
  • Koch MJ, Hesketh-Best PJ, Smerdon G, Warburton PJ, Howell K & Upton M 2021 'Impact of growth media and pressure on the diversity and antimicrobial activity of isolates from two species of hexactinellid sponge' Microbiology 167, (12) , DOI Open access
  • Mathur H, Field D, Upton M & Cotter PD 2021 'Editorial: Bacteriocins and Other Ribosomally Synthesised and Post-translationally Modified Peptides (RiPPs) as Alternatives to Antibiotics' Frontiers in Microbiology 12, , DOI Open access
  • Liu Y, Tong Z, Shi J, Li R, Upton M & Wang Z 2021 'Drug repurposing for next-generation combination therapies against multidrug-resistant bacteria' Theranostics 11, (10) 4910-4928 Publisher Site , DOI Open access
  • Hesketh-Best PJ, Mouritzen MV, Shandley-Edwards K, Billington RA & Upton M 2021 'Galleria mellonella larvae exhibit a weight-dependent lethal median dose when infected with methicillin-resistant Staphylococcus aureus' Pathogens and Disease 79, (2) , DOI Open access
  • Ksiazczyk M, Dudek B, Kuczkowski M, O’Hara R, Korzekwa K, Wzorek A, Korzeniowska-Kowal A, Upton M, Junka A & Wieliczko A 2021 'The Phylogenetic Structure of Reptile, Avian and Uropathogenic Escherichia coli with Particular Reference to Extraintestinal Pathotypes' International Journal of Molecular Sciences 22, (3) 1192-1192 , DOI Open access
  • Comber SDW, Upton M, Lewin S, Powell N & Hutchinson TH 2020 'COVID-19, antibiotics and One Health: a UK environmental risk assessment' Journal of Antimicrobial Chemotherapy , DOI Open access
  • Hammond K, Lewis H, Halliwell S, Desriac F, Nardone B, Ravi J, Hoogenboom BW, Upton M, Derrick JP & Ryadnov MG 2020 'Flowering poration – a synergistic multi-mode antibacterial mechanism by a bacteriocin fold' iScience 101423-101423 , DOI Open access
  • Aldarhami A, Felek A, Sharma V & Upton M 2020 'Purification and characterization of nisin P produced by a strain of Streptococcus gallolyticus' Journal of Medical Microbiology , DOI Open access
  • Alghoribi MF, Doumith M, Upton M, Al Johani SM, Alzayer M, Woodford N, Ellington MJ & Balkhy HH 2019 'Complete Genome Sequence of a Colistin-Resistant Uropathogenic Escherichia coli Sequence Type 131 fimH22 Strain Harboring mcr-1 on an IncHI2 Plasmid, Isolated in Riyadh, Saudi Arabia' Microbiology Resource Announcements 8, (18) , DOI Open access
  • O'Hara RW, Jenks PJ, Emery M & Upton M 2018 'Rapid detection of extra-intestinal pathogenic Escherichia coli multi-locus sequence type 127 using a specific PCR assay' Journal of Medical Microbiology Author Site , DOI Open access
  • Castelino M, Eyre S, Moat J, Fox G, Martin P, Ho P, Upton M & Barton A 2017 'Optimisation of methods for bacterial skin microbiome investigation: primer selection and comparison of the 454 versus MiSeq platform' BMC Microbiology 17, (1) , DOI Open access
  • Halliwell S, Warn P, Sattar A, Derrick JP & Upton M 2016 'A single dose of epidermicin NI01 is sufficient to eradicate MRSA from the nares of cotton rats' Journal of Antimicrobial Chemotherapy dkw457-dkw457 , DOI Open access
  • Sarkar S, Roberts LW, Phan M-D, Tan L, Lo AW, Peters KM, Paterson DL, Upton M, Ulett GC & Beatson SA 2016 'Comprehensive analysis of type 1 fimbriae regulation in fimB -null strains from the multidrug resistant Escherichia coli ST131 clone' Molecular Microbiology , DOI Open access
  • Moat J, Rizoulis A, Fox G & Upton M 2016 'Domestic shower hose biofilms contain fungal species capable of causing opportunistic infection' Journal of Water and Health , DOI Open access

Articles 2013 – 2015

Forde BM, Phan M-D, Gawthorne JA, Ashcroft MM, Stanton-Cook M, Sarkar S, Peters KM, Chan K-G, Chong TM & Yin W-F (2015) 'Lineage-Specific Methyltransferases Define the Methylome of the Globally Disseminated Escherichia coli ST131 Clone' mBio 6, (6). Read the article
Alghoribi MF, Gibreel TM, Farnham G, Al Johani SM, Balkhy HH & Upton M (2015) 'Antibiotic-resistant ST38, ST131 and ST405 strains are the leading uropathogenicEscherichia coliclones in Riyadh, Saudi Arabia' Journal of Antimicrobial Chemotherapy 70, (10) pp 2757-2762. Read the article
Morra R, Shankar J, Robinson CJ, Halliwell S, Butler L, Upton M, Hay S, Micklefield J & Dixon N (2015) 'Dual transcriptional-translational cascade permits cellular level tuneable expression control' Nucleic Acids Research 44, (3) pp e21-e21. Read the article
Phan M-D, Peters KM, Sarkar S, Forde BM, Lo AW, Stanton-Cook M, Roberts LW, Upton M, Beatson SA & Schembri MA (2015) 'Third-generation cephalosporin resistance conferred by a chromosomally encoded blaCMY-23 gene in the Escherichia coli ST131 reference strain EC958' Journal of Antimicrobial Chemotherapy 70, (7) pp 1969-1972. Read the article
Phan MD, Forde BM, Peters KM, Sarkar S, Hancock S, Stanton-Cook M, Ben Zakour NL, Upton M, Beatson SA & Schembri MA (2015) 'Molecular characterization of a multidrug resistance IncF plasmid from the globally disseminated Escherichia coli ST131 clone' PLoS One 10, (4). Read the article
AlRabiah H, Xu Y, Rattray NJW, Vaughan AA, Gibreel T, Sayqal A, Upton M, Allwood JW & Goodacre R (2014) 'Multiple metabolomics of uropathogenic E. coli reveal different information content in terms of metabolic potential compared to virulence factors' Analyst 139, (17) pp 4193-4199. Read the article
Dawson SE, Gibreel T, Nicolaou N, AlRabiah H, Xu Y, Goodacre R & Upton M (2014) 'Implementation of Fourier transform infrared spectroscopy for the rapid typing of uropathogenic Escherichia coli' European Journal of Clinical Microbiology and Infectious Diseases 33, (6) pp 983-988. Read the article
Castelino M, Eyre S, Upton M, Ho P & Barton A (2014) 'The bacterial skin microbiome in psoriatic arthritis, an unexplored link in pathogenesis: challenges and opportunities offered by recent technological advances' Rheumatology (Oxford) 53, (5) pp 777-784. Read the article
Petty NK, Zakour NLB, Stanton-Cook M, Skippington E, Totsika M, Forde BM, Phan MD, Moriel DG, Peters KM & Davies M (2014) 'Global dissemination of a multidrug resistant Escherichia coli clone' Proceedings of the National Academy of Sciences of the United States of America 111, (15) pp 5694-5699. Read the article
Allwood JW, AlRabiah H, Correa E, Vaughan A, Xu Y, Upton M & Goodacre R (2014) 'A workflow for bacterial metabolic fingerprinting and lipid profiling: application to Ciprofloxacin challenged Escherichia coli' Metabolomics 1-16. Read the article
Alghoribi MF, Gibreel TM, Dodgson AR, Beatson SA & Upton M (2014) 'Galleria mellonella infection model demonstrates high lethality of ST69 and ST127 uropathogenic E. coli' PLoS One 9, (7). Read the article
Forde BM, Ben Zakour NL, Stanton-Cook M, Phan M-D, Totsika M, Peters KM, Chan KG, Schembri MA, Upton M & Beatson SA (2014) 'The complete genome sequence of Escherichia coli EC958: a high quality reference sequence for the globally disseminated multidrug resistant E. coli O25b:H4-ST131 clone' PLoS One 9, (8) Read the article
Voets GM, Leverstein-van Hall MA, Kolbe-Busch S, van der Zanden A, Church D, Kaase M, Grisold A, Upton M, Cloutman-Green E & Cantón R (2013) 'International multicenter evaluation of the DiversiLab bacterial typing system for Escherichia coli and Klebsiella spp' Journal of Clinical Microbiology 51, (12) pp 3944-3949. Read the article
Phan MD, Peters KM, Sarkar S, Lukowski SW, Allsopp LP, Moriel D, Achard ME, Totsika M, Marshall VM & Upton M (2013) 'The Serum Resistome of a Globally Disseminated Multidrug Resistant Uropathogenic Escherichia coli Clone' PLoS Genet 9, pp e1003834-e1003834. Read the article
Totsika M, Kostakioti M, Hannan TJ, Upton M, Beatson SA, Janetka JW, Hultgren SJ & Schembri MA (2013) 'A FimH inhibitor prevents acute bladder infection and treats chronic cystitis caused by multidrug-resistant uropathogenic Escherichia coli ST131' Journal of Infectious Diseases 208, (6) pp 921-928. Read the article
Gibreel TM & Upton M (2013) 'Synthetic epidermicin NI01 can protect Galleria mellonella larvae from infection with Staphylococcus aureus' Journal of Antimicrobial Chemotherapy. Read the article
Handley KM, Upton M, Beatson SA, Héry M & Lloyd JR (2013) 'Genome Sequence of Hydrothermal Arsenic-Respiring Bacterium Marinobacter santoriniensis NKSG1T' Microbiology Genome Announcements 1, (3). Read the article
Govindji N, Wills P, Upton M, Tirelli N, Yeates S & Webb M (2013) 'The antibiofilm effects of Byotrol™ G32' Journal of Applied Microbiology 114, (5) pp 1285-1293. Read the article
AlRabiah H, Correa E, Upton M & Goodacre R (2013) 'High-throughput phenotyping of uropathogenic E. coli isolates with Fourier transform infrared spectroscopy' Analyst 138, (5) pp 1363-1369. Read the article