Adulthood

Our public health cross-cutting theme brings together researchers, clinicians, practitioners and expertise in systematic reviews, epidemiological studies, the design and evaluation of complex interventions and service evaluation to deliver improved health and social care for patient and public benefit.

One strand of this focuses on Health and behaviour change (led by Adrian Taylor) and includes NIHR-funded trials such as e-coachER, a web-based coaching/exercise referral scheme for patients with chronic physical and mental health conditions; TARS, a trial to assess the effectiveness of new physical activity support to help smokers who want to reduce but not quit; and Strengthen which aims to improve health for those under community supervision, with the support of a Health Trainer. Taylor co-founded and is Editor in Chief of Mental Health & Physical Activity, an international and multi-disciplinary journal in this field.

Highlights include the identification of biomarkers which will help predict patient response to treatment (Hanemann, Hutchinson); novel therapeutics for lymphoma (Hutchinson); and the prevention and treatment of oral and skin cancers (Bing Hu).

In addition to our Earlybird research, which identifies childhood and adolescent risk factors for adult diabetes, we have a strong focus on the impact of obesity on people with diabetes and other endocrine conditions, and developing new approaches to treatment (Pinkney).

Research supporting the evidence based management of people with diabetes is an important focus of the Rehabilitation Research Group. The Balance Enhancement and Ulcer Prevention (BEUP) group is an academic/NHS multidisciplinary collaboration, which aims to translate the results from our published research to influence and inform everyday clinical practice with respect to diabetes and neuropathy.

Applying specialist knowledge of diabetic foot self-care and education and ulcer prevention and management with focus onfoot pressure analysis, orthotic design and balance problems the team is developing and testing a battery of interventions to make walking safer for people with diabetes.

Highlights in applied research include an automated 3D-printed insole, a novel balance enhancement insole and a clinical trial testing pressure data guided insoles (Paton, Marsden, Collings).

Led by Richard Byng, the Community and Primary Care Research Group is researching mental health in a range of community-based settings.

Recent project include Partners 2, an NIHR funded Programme aiming to help primary care and community based mental health services work more closely together by developing a system of collaborative care based in GP surgeries for people with schizophrenia and bipolar disorder; and Engager which developed ways of organising care for men with common mental health problems as they approached being released from prison (Byng, Callaghan, Quinn, Rybczynska-Bunt).

The group has been working alongside key stakeholders to shape and define services to better fit the needs of ex-offenders, such as Street Triage and the Neighbourhood Liaison and Diversion intervention, services that aim to divert people away from the Criminal Justice System (Callaghan, Hazeldine).

Mental health problems often include and/or are exacerbated by problems of substance use. Work in this area includes PHASED, a study examining research on physical activity in relation to alcohol and substance use disorders (Thompson) and Flourish in Nature, a project supporting alcohol and drug use recovery through volunteer opportunities in natural environments (Thompson).

Lloyd and Close are also investigating the role of online gaming and gambling behaviours and the impact of these on wellbeing of the UK adult population. This work has also included a targeted ‘lock down’ survey to measure the impact of COVID-19 restrictions on this behaviour.

Andrade is testing the use of Functional imagery training to reduce alcohol-related harm; while ongoing research takes place across the faculty into new and inventive forms of psychological intervention to target mental health difficulties (Whalley, Sharpe, Lloyd, Norman).

We host internationally renowned research in the field of MS. Hobart has led several clinical studies/trials into the assessment and treatment of MS and the design, testing and validation of patient outcome scales for clinical application. The MS scales are among a limited number contained in the United States Food and Drugs Administration (FDA) compendium of Clinical Outcomes Assessments.

Combining pathophysiology, behavioural science and health care practice, our Rehabilitation Research Group also conducts a range of research on MS.

Trials evaluating the effectiveness of whole-care packages and targeted interventions include Standing Up in Multiple Sclerosis, a multi-centre randomised controlled study to assess the effectiveness of a home-based self-management standing frame programme in people with progressive MS (Freeman) and Balance Right in Multiple Sclerosis (BRiMS), a guided self-management programme to reduce falls and improve quality of life, balance and mobility (Gunn, Freeman).

Gunn has investigated risk factors associated with falls in people with MS and co-developed a falls management intervention (Endacott, Marsden, Freeman); while Grose has explored the confidante relationship in people with MS.