The Research Excellence Framework is the system for assessing the quality of research in UK higher education institutions. As part of this system, universities are required to submit ‘impact case studies’ to demonstrate the impact of their research on wider economy and society.
REF Impact Case Studies
Demonstrating Plymouth Institute of Health and Care Research (PIHR) knowledge mobilisation impact through REF Impact Case Studies
PIHR case study examples
Jackie Andrade’s work shows how research on consciousness can lead to real-world changes in medical practice (anaesthesia).
Phillip Buckhurst’s work on intraocular lens assessment and ophthalmic instrumentation has produced new image analysis methods for assessing the stability of intraocular lenses implanted during cataract surgery, which have been used in clinical trials leading to FDA approval.
Marie Bryce and colleagues have identified critical challenges presented by the implementation of medical revalidation, including doctors’ difficulties in collecting supporting information and variation in local requirements and decision-making processes. In response to these findings, the General Medical Council clarified its requirements and made changes to its guidance documents.
Matthew Cramp’s work has influenced NICE guidelines for the treatment of Hepatitis C by showing that specific anti-virals cure Hepatitis C infection in over 95% of cases.
Judy Edworthy has led work on the development and testing of new alarms that meet global medical device safety standards in order to combat ‘alarm fatigue’, a problem recognized throughout clinical care as a safety issue relevant to both staff and patients, as well as an important issue for the multi-billion dollar medical device industry.
Jennifer Freeman’s development of an innovative pelvic orthotic product for pelvic girdle dysfunction has enhanced sporting performance, for example in medal winning Paralympian sports as diverse as athletics, paracycling and canoeing. The product has also improved pain control for pregnant women.
Jeremy Hobart's research programme focuses on the development of Patient Reported Outcome measures (PROs) for clinical research, trials and drug licensing. The scales he has developed for assessing Multiple Sclerosis (MS) are among a limited number contained in the United States Food and Drugs Administration (FDA) compendium of Clinical Outcomes Assessments. Since 2014 Hobart has developed new scales in MS and Stroke and worked as part of the LORA group to support scale development in dermatology (hyperhidrosis), urology (nocturia) and haematology (sickle cell symptom severity).
The Severe Asthma Questionnaire (SAQ) developed by Rupert Jones, Michael Hyland, Joseph Lanario and colleagues has become a key measure of quality of life in leading severe asthma services across Europe. It is also included in the International Severe Asthma Registry (ISAR) which receives data from over 22 countries and creates a data platform that is used in a range of commercially sponsored studies.
The Empowerment of Parents in the Intensive Care (EMPATHIC) outcome measures led by Jos Latour has international recognition; the EMPATHIC instruments in neonatal intensive care have been listed as the gold standard in the European Standards of Care in Newborn Health presented to the European Commission (2018). The EMPATHIC instruments have been translated and validated in several languages (Chinese, French, Spanish, Portuguese, Greek, Turkish, Arabic) and are used in over 40 countries where in some cases they are the national standard quality indicator in paediatric critical care medicine.
Helen Lloyd has led a team the development of a model, toolkit, and guidance to implement Person Centred Care through a programme of mixed methods research and collaboration within NHS settings. Within this model, patients are viewed as people with capabilities that can be harnessed through personalised goal setting to improve self-management and self-efficacy. Goals are then used to drive a coordinated service response. This is a radical shift from the traditional view of patients as passive recipients of care. Lloyd’s work on co-ordinated, person-centered healthcare has led to changes in government policy and health service practice
Mona Nasser identifies and evaluates methods to ensure resources are allocated to research projects that are relevant to stakeholders, meet high scientific quality standards and avoid wasteful investment. These innovative methods have been incorporated into guidelines of the World Health Organisation and Cochrane.
Carl Roobottom’s work has led to NICE recommending Cardiac Computed Tomographic Angiography as the primary diagnostic tool for all chest-pain patients in the UK, 340,000 patients per annum.
Simon Rule has shown that specific novel therapies for Mantle Cell lymphoma double mean life expectancy, leading to international licensing (90 countries worldwide) with over 200,000 patients worldwide treated.