Dr Yinghui Wei
Profiles

Dr Yinghui Wei

Associate Professor of Statistics

School of Engineering, Computing and Mathematics (Faculty of Science and Engineering)

Dr Yinghui Wei can be contacted through arrangement with our Press Office, to speak to the media on these areas of expertise.
  • Applied statistics
  • Statistical methodology
  • Clinical trials
  • Observational studies
Biography

Biography

  • Associate Professor of Statistics
  • School Lead for Equality, Diversity and Inclusion

Qualifications

Academic qualifications:

  • PhD in Statistics, School of Mathematics, University of Manchester, UK, 2008
  • MSc in Statistics (with Distinction), School of Mathematics, University of Manchester, UK, 2004
  • BSc in Mathematics and Applied Mathematics, Northwest University, China, 2003
Professional qualifications:
  • Office of National Statistics Full Accredited Researcher under the Digital Economy Act, 2021
  • Fellow, Higher Education Academy, 2014
  • Postgraduate Certificate in Academic Practice, University of Plymouth, UK, 2014
Appointments:
  • Associate Professor of Statistics, University of Plymouth, UK, 2019 – Present
  • Lecturer in Statistics, University of Plymouth, UK, 2013 – 2019
  • Investigator Scientist, Medical Research Council, UK, 2009 – 2013
  • Research Fellow (Welcome Trust), University of Nottingham, UK, 2008 – 2009

Honorary Appointments:

  • Visiting Senior Research Fellow, Bristol Medical School, University of Bristol, 2021 – Present

Professional membership

  • Member of Cochrane Statistical Methods Group
  • Fellow of the Royal Statistical Society
  • Fellow of the Higher Education Academy
  • Member of the London Mathematical Society

Roles on external bodies

  • Statistical Editor, Cochrane Developmental Psychosocial Learning Problems Group
  • Chair, Royal Statistical Society South West Local Group

Teaching

Teaching

Teaching interests


I supervise UG projects in the Statistics in Context module as well as MSc projects in statistics and data analytics. Recent projects include the analysis of patient reported outcomes in multiple sclerosis, estimation of reproduction number for COVID19, as well as predictive analytics for social housing and telecommunication industry. 

I was Stage 1 Tutor for BSc (Hons) Mathematics programmes for three years (2018 – 2021).  

Staff serving as external examiners

2022 – , External Examiner, "MSc Data Science", "BSc Statistics", "BSc Data Science and Analytics", Department of Mathematical Sciences, University of Essex

2019, External PhD Examiner, Department of Health Data Science, University of Liverpool

Research

Research

Research interests

I recently hold an MRC fellowship grant to make use of big data from cohort studies and electronic health records within the Trusted Research Environments, such as the OpenSAFELY and UK Longitudinal Linkage Collaboration Secure e-Research Platform, to investigate COVID-19 epidemiology and its impact on public health.

My primary research interest is in developing statistical methodology and the substantive applications to medicine, clinical trials, observational studies and evidence synthesis. Specific areas include:

  • Bayesian inference
  • Clinical prediction models
  • Evidence synthesis and meta-analysis (including multiple outcomes, multiple treatments and diagnostic tests meta-analysis)
  • Modelling and analysis of infectious diseases epidemiology (including Cowpox virus, healthcare-associated infection, Zika virus and COVID-19) 
  • Survival analysis

I have a software package in Stata: ipdfc

Wei Y. and Royston P. IPDFC: Stata module to reconstruct individual participant data from a published Kaplan-Meier curve (link)

Other research

Big Data group

Centre for Mathematical Sciences

Research degrees awarded to supervised students

Dr Nicole Thomas (2022) Investigation of the effectiveness of an intervention to prevent oral disease in a highly vulnerable child population (co-supervisor)
Dr Jagriti Sethi (2022) Graphene based biosensors for detection of blood biomarkers of Alzheimer's disease (co-supervisor)
Dr Lexy Sorrell (2021) Statistical inference about bivariate semi-competing risk data using copulas (Director of Studies)
Dr Zainab Al-Kaabawi (2018) Bayesian Hierarchical Models for Linear Networks (Director of Studies)

Current PhD Students:
  • M. Howe: A probabilistic dental treatment risk index (co-supervisor) 
  • L. Zhang: Bayesian multi-level survival models (Director of Studies)
  • S. Riley: Using big data to develop and validate clinical prediction models for survival outcomes following kidney transplant (Director of Studies) 
Visiting PhD Students:
  • J. Li: Survival analysis (Overseas supervisor, Yunnan University)
  • Y. Zhou: Spatial-temporal modelling (Overseas supervisor, Yunnan University)

Grants & contracts

Externally funded projects:

01/02/2023 – 31/01/2027, Horizon Europe, Peripheral Biomarker Based Combinatorial Early Diagnostics for Dementia (CombiDiag), €2.8M;  Co-I; PI: G. Pan; T. Stefan.

01/09/2022 – 31/08/2024, NIHR (302739), "Risk factors for adverse health outcomes following kidney transplantation", £89,205, Primary Supervisor; Pre-Doctoral Fellow Gray J.

01/08/2022 – 31/07/2023, EPSRC IAA, "Using data and analytical approaches to improve healthcare services for patient and public benefit", £5,000, PI.

01/04/2022– 1/10/2023, Royal Academy of Engineering Diversity Impact Programme, "Embedding Systemic Inclusion for Neurodiverse and Disabled Engineering Students", Co-I, £93,667, PI Khan A. 

1/10/2021 – 30/09/2022, MRC Fellowship (MR/W021358/1): "Using data to improve public health: COVID-19 secondment", PI, £117,805. This fellowship is part of the COVID-19 Longitudinal Health and Wellbeing National Core Study award. 

03/2021, London Mathematical Society (WiM 20-21 04): Women in Mathematics Day, Lead Applicant, £1,600.

2020 – 2023, China Scholarship Council: Joint Training of Doctoral Students in Statistical Science with Yunnan University, Host Supervisor.

1/10/2020 – 30/09/2024, University Hospitals Plymouth NHS Trust (Ref: 1374) and EPSRC DTP (Ref: EP/T518153/1: 2432390): "Using big data to develop and validate clinical prediction models for survival outcomes in kidney transplant", Project PI, £84,786 (with £34,000 from NHS).

04/2019 – 12/2020, GlaxoSmithKline (Ref: 8894): “An assessment of the sensitivity to change of a scale to measure quality of life in patients with severe asthma”, awarded in 2018, Co-I, £55,754.

04/2019 – 04/2020, GlaxoSmithKline (Ref: 8893): “Further validation of a scale to measure quality of life in patients with severe asthma”, awarded in 2018, Co-I, £44,503.

07/2016 – 01/2018, NIHR RfPB (PB-PG-0215-36117): “A systematic review of physical activity for alcohol and substance use disorders: evidence synthesis with stakeholder engagement to formulate practical recommendations”, awarded in 2015, Co-I, £154,528, PI Thompson T. 

Publications

Publications

Key publications

Other Publications

Google Scholar   Research Gate  

Key publications are highlighted

Journals
Articles
Riley S, Zhang Q, Tse W-Y, Connor A & Wei Y (2022) 'Using information available at the time of donor offer to predict kidney transplant survival outcomes: a systematic review of prediction models' Transplant International 35, , DOI Open access
Prestige E, Stander J & Wei Y (2022) 'Covid lockdowns in the UK: Estimating their effects on transmission' Significance 19, (2) 14-18 , DOI Open access
Sorrell A, Wei Y, Wojtys M & Rowe P (2021) 'Estimating the correlation between semi-competing risk survival endpoints' Biometrical Journal: journal of mathematical methods in biosciences , DOI Open access
Sethi J, Suhail A, Safarzadeh M, Sattar A, Wei Y & Pan G (2021) 'NH2 linker for femtomolar label-free detection with reduced graphene oxide screen-printed electrodes' Carbon 179, 514-522 , DOI Open access
Hernandez-Vaquero D, Vigil-Escalera C, Pérez-Méndez I, Gutiérrez A, Avanzas P, Wei Y, Diaz R, Silva J, Moris C & Pascual I (2021) 'Survival After Thoracoscopic Surgery or Open Lobectomy: Systematic Review and Meta-Analysis' The Annals of Thoracic Surgery 111, (1) 302-313 , DOI
Al-kaabawi Z, Wei Y & Moyeed R (2020) 'Bayesian hierarchical models for linear networks' Journal of Applied Statistics 1-28 , DOI Open access
Thompson TP, Horrell J, Taylor AH, Wanner A, Husk K, Wei Y, Creanor S, Kandiyali R, Neale J & Sinclair J (2020) 'Physical activity and the prevention, reduction, and treatment of alcohol and other drug use across the lifespan (The PHASE review): A systematic review' Mental Health and Physical Activity 0-0 Author Site , DOI Open access
Wei Y (2020) 'The Zika Virus Individual Participant Data Consortium: A Global Initiative to Estimate the Effects of Exposure to Zika Virus during Pregnancy on Adverse Fetal, Infant, and Child Health Outcomes' Tropical Medicine and Infectious Disease 5, (4) 152-152 , DOI Open access
Horrell J, Thompson TP, Taylor AH, Neale J, Husk K, Wanner A, Creanor S, Wei Y, Kandiyali R & Sinclair J (2020) 'Qualitative systematic review of the acceptability, feasibility, barriers, facilitators and perceived utility of using physical activity in the reduction of and abstinence from alcohol and other drug use' Mental Health and Physical Activity 100355-100355 Author Site , DOI Open access
Lanario JW, Hyland ME, Wei Y, Jones RC & Masoli M (2020) 'Comparison of the effects of pulmonary and extra-pulmonary symptoms on health-related quality of life in patients with severe asthma' Respiratory Medicine 162, 105870-105870 , DOI Open access
O'Hara L, Smith ER, Barlow J, Livingstone N, Herath NINS, Wei Y, Spreckelsen TF & Macdonald G (2019) 'Video feedback for parental sensitivity and attachment security in children under five years' Cochrane Database of Systematic Reviews 2019, (11) , DOI
Jones R, Lanario J, Hyland M, Wei Y & Masoli M (2019) 'Evidence for similarity in symptoms and mechanism: the extra-pulmonary symptoms of severe asthma and polysymptomatic presentation of fibromyalgia' Immunity, Inflammation & Disease , DOI Open access
Wilder-Smith A, Wei Y, Araújo TVBD, VanKerkhove M, Turchi Martelli CM, Turchi MD, Teixeira M, Tami A, Souza J & Sousa P (2019) 'Understanding the relation between Zika virus infection during pregnancy and adverse fetal, infant and child outcomes: a protocol for a systematic review and individual participant data meta-analysis of longitudinal studies of pregnant women and their infants and children' BMJ Open 9, (6) e026092-e026092 , DOI Open access
van Kampen SC, Jones R, Kisembo H, Houben RMGJ, Wei Y, Mugabe FR, Rutebemberwa E & Kirenga B (2018) 'Chronic respiratory symptoms and lung abnormalities among people with a history of tuberculosis in Uganda: a national survey' Clinical Infectious Diseases Author Site , DOI Open access
Dalla Valle L, Stander J, Gresty K, Eales J & Wei Y (2018) 'Stakeholder Perspectives on Graphical Tools for Visualising Student Assessment and Feedback Data' Research in Learning Technology , DOI Open access
De Crescenzo F, Ziganshina LE, Yudina EV, Kaplan YC, Ciabattini M, Wei Y & Hoyle CHV (2018) 'Noradrenaline reuptake inhibitors (NRIs) for attention deficit hyperactivity disorder (ADHD) in adults' Cochrane Database of Systematic Reviews , DOI
Barlow J, Herath NINS, Bartram Torrance C, Bennett C & Wei Y (2018) 'The Neonatal Behavioral Assessment Scale (NBAS) and Newborn Behavioral Observations (NBO) system for supporting caregivers and improving outcomes in caregivers and their infants' Cochrane Database of Systematic Reviews 2018, (3) , DOI
Pang CL, Pilkington N, Wei Y, Peters J, Roobottom C & Hyde C (2018) 'A methodology review on the incremental prognostic value of computed tomography biomarkers in addition to Framingham risk score in predicting cardiovascular disease: the use of association, discrimination and reclassification' BMC Cardiovascular Disorders 18, (1) 39-39 Author Site , DOI Open access
Thompson TP, Taylor AH, Wanner A, Husk K, Wei Y, Creanor S, Kandiyali R, Neale J, Sinclair J & Nasser M (2018) 'Physical activity and the prevention, reduction, and treatment of alcohol and/or substance use across the lifespan (The PHASE review): protocol for a systematic review' Systematic Reviews 7, (1) Author Site , DOI Open access
Wei Y & Royston P (2017) 'Reconstructing time-to-event data from published Kaplan–Meier curves' Stata Journal 17, (4) 786-802 Publisher Site , DOI Open access
Barlow J, Bennett C, Midgley N, Larkin SK & Wei Y (2017) 'Parent–infant psychotherapy for improving parental and infant mental health' BJPsych Advances 23, (4) 216-216 , DOI
Barlow J, Bennett C, Midgley N, Larkin SK & Wei Y (2016) 'Parent–infant psychotherapy: a systematic review of the evidence for improving parental and infant mental health' Journal of Reproductive and Infant Psychology 34, (5) 464-482 , DOI
Barlow J, Bergman H, Kornør H, Wei Y & Bennett C (2016) 'Group-based parent training programmes for improving emotional and behavioural adjustment in young children' Cochrane Database of Systematic Reviews , DOI
Wei Y, Kypraios T, O’Neill PD, Huang SS, Rifas-Shiman SL & Cooper BS (2016) 'Evaluating hospital infection control measures for antimicrobial-resistant pathogens using stochastic transmission models: Application to vancomycin-resistant enterococci in intensive care units' Statistical Methods in Medical Research 27, (1) 269-285 , DOI Open access
Wei Y, Royston P, Tierney JF & Parmar MKB (2015) 'Meta-analysis of time-to-event outcomes from randomized trials using restricted mean survival time: application to individual participant data' Statistics in Medicine 34, (21) 2881-2898 , DOI
Hollands GJ, Shemilt I, Marteau TM, Jebb SA, Lewis HB, Wei Y, Higgins JPT & Ogilvie D (2015) 'Portion, package or tableware size for changing selection and consumption of food, alcohol and tobacco' Cochrane Database of Systematic Reviews 2018, (11) , DOI
Mantzari E, Vogt F, Shemilt I, Wei Y, Higgins JPT & Marteau TM (2015) 'Personal financial incentives for changing habitual health-related behaviors: A systematic review and meta-analysis' Preventive Medicine 75, 75-85 , DOI
Barlow J, Bennett C, Midgley N, Larkin SK & Wei Y (2015) 'Parent-infant psychotherapy for improving parental and infant mental health' Cochrane Database of Systematic Reviews 2015, (1) , DOI
Barlow J, Bennett C, Midgley N, Larkin SK & Wei Y (2015) 'Parent‐infant Psychotherapy for Improving Parental and Infant Mental Health: A Systematic Review' Campbell Systematic Reviews 11, (1) 1-223 , DOI
Turner RM, Jackson D, Wei Y, Thompson SG & Higgins JPT (2014) 'Predictive distributions for between‐study heterogeneity and simple methods for their application in Bayesian meta‐analysis' Statistics in Medicine 34, (6) 984-998 , DOI Open access
Xiong T, Turner RM, Wei Y, Neal DE, Lyratzopoulos G & Higgins JPT (2014) 'Comparative efficacy and safety of treatments for localised prostate cancer: an application of network meta-analysis' BMJ Open 4, (5) e004285-e004285 , DOI Open access
Hollands GJ, Shemilt I, Marteau TM, Jebb SA, Lewis HB, Wei Y, Higgins JPT & Ogilvie D (2014) 'Portion, package or tableware size for changing selection and consumption of food, alcohol and tobacco' , DOI
Royston P, Wei Y, Tierney J & Parmar M (2013) 'Analysis of survival data from trials with non-proportional hazards: an empirical comparison of methods' Trials 14, (S1) , DOI
Wei Y & Higgins JPT (2013) 'Bayesian multivariate meta-analysis with multiple outcomes' Statistics in Medicine 32, (17) 2911-2934 , DOI
Wei Y & Higgins JPT (2012) 'Estimating within‐study covariances in multivariate meta‐analysis with multiple outcomes' Statistics in Medicine 32, (7) 1191-1205 , DOI
Wei Y, Neal P, Telfer S & Begon M (2012) 'Statistical analysis of an endemic disease from a capture–recapture experiment' Journal of Applied Statistics 39, (12) 2759-2773 , DOI
Wright CF, Wei Y, Higgins JPT & Sagoo GS (2012) 'Non-invasive prenatal diagnostic test accuracy for fetal sex using cell-free DNA a review and meta-analysis' BMC Research Notes 5, (1) , DOI Open access
Books
James G, Dyke P, Searl J, Craven M & Wei Y (2020) Modern Engineering Mathematics. 6th Ed. Pearson Publisher Site
Presentations and posters
Lanario J, Hyland M, Wei Y, Jones R & Masoli M Lanario J, Hyland M, Wei Y, Jones R & Masoli M 'P167 The contribution of extra-pulmonary symptoms of quality of life in severe asthma are important and may be overlooked' , DOI
Jones R, Lanario J, Wei Y, Hyland M & Masoli M Jones R, Lanario J, Wei Y, Hyland M & Masoli M 'Non-Respiratory Symptoms Are as Important as Respiratory Symptoms in Their Impact on Quality of Life in Severe Asthma' , DOI
Personal

Personal

Reports & invited lectures

Reports:
  • Wei Y., Broomhead N., Christopher C. and Robertz D. (2021) "Report: LMS Women in Mathematics Day 2021", London Mathematical Society Newsletter, Issue 495, July 2021, 19-20.
  • Wei Y. (2019) "South West local group meeting: Network Time Series".
  • Wei Y. (2019) “South West local group meeting: Modelling numbers of births” .
  • Wei Y. (2018) “South West local group meeting: Evidence synthesis in health” .

Selected Seminars/Talks/Posters:
  • 2022: Poster: "Risk factors for long COVID: big data analytics using OpenSAFELY", Royal Statistical Society International Conference, Aberdeen
  • 2022: Contributed talk: "Bivariate copula regression models for semi-competing risks", Royal Statistical Society International Conference, Aberdeen
  • 2022: Invited talk: "Using data to improve public health: COVID secondment - Overview of Experience", COVID-19 Longitudinal Health and Wellbeing National Core Study Workshop, UCL
  • 2022: Invited talk: "Risk factors for long COVID", COVID-19 Longitudinal Health and Wellbeing National Core Study Workshop, UCL
  • 2020: Invited talk, "The arts and techniques of online teaching for mathematics and statistics", Shanghai Polytechnic University
  • 2019: Contributed talk, "Estimating the correlation between bivariate survival endpoints", Royal Statistical Society International Conference, Belfast
  • 2019: Invited talk, "Statistical Applications in Medical Sciences", INSPIRE Interdisciplinary Meeting, Plymouth.
  • 2018: Invited talk, "Survival analysis of patients following kidney transplantation" (with Lexy Sorrell), South West Transplant Centre Annual Transplant Day, Totnes.
  • 2018: Invited talk, "Survival analysis: from individual level data to aggregate data", Yunnan University, China.
  • 2018: Invited talk, "Survival analysis: from individual level data to aggregate data", AUFE, China.
  • 2017: Invited talk, "Restricted mean survival time: from individual level data to aggregate data", CMStatistics 2017, University of London, London.
  • 2017: Session chair, "Recent Advances in Research Synthesis Methods", CMStatistics 2017, University of London, London.
  • 2017: Contributed talk, "Using published Kaplan-Meier curves to reconstruct time-to-event data for secondary analyses", Royal Statistical Society International Conference, Glasgow. 
  • 2017: Contributed poster, "Hierarchical Bayesian models for road traffic accidents", Royal Statistical Society International Conference, Glasgow. 
  • 2016: Invited lecture, "Introduction to Design and Analysis of Clinical Trials", postgraduate summer school, University of Electronic Science and Technology of China, Chengdu.
  • 2015: Invited seminar, "The use of restricted mean survival time in meta-analysis of clinical trials with time-to-event outcomes". University of Exeter, Exeter.
  • 2014: Invited seminar, "Meta-analysis of survival data using restricted mean survival time", University of Essex, Colchester.
  • 2013: Contributed talk, "Analysis of survival data from trials with non-proportional hazards". Clinical Trials Methodology Conference: Methodology Matters, Edinburgh. 
  • 2013: Contributed talk, "Network Meta-analysis", Methodology Theme Meeting, MRC Clinical Trials Unit, London.
  • 2012: Contributed poster, "Bayesian multivariate meta-analysis with many outcomes", 33rd Annual Conference of International Society for Clinical Biostatistics, Bergen.
  • 2011: Contributed talk, "Bayesian multivariate meta-analysis with many outcomes", Methods in Meta-analysis Meeting, Royal Statistical Society, London.
  • 2010: Internal Seminar, "Multivariate meta-analysis with multiple outcomes", MRC Biostatistics Unit, Cambridge. 
  • 2010: Invited lecture, "Introduction to Meta-analysis", Shanghai Nottingham Systematic Review Course, Shanghai Jiao Tong University, Shanghai. 
  • 2007: Poster presentation, "An epidemic model for discrete data in dynamic population", Manchester Research Student Conference in Statistics and Probability, University of Manchester.
  • 2007: Contributed talk, "Statistical inference about epidemics in dynamic population", Research Student Conference in Statistics and Probability, Durham, UK.

Conferences organised

Sept 2022: Health Data Science for COVID-19 Research, Invited Session, Royal Statistical Society International Conference
March 2021: LMS Women in Mathematics Day
October 2020: Joint RSS South West Local Group - Impact Lab event: Early Career Researchers' Health Data Science Symposium.
2018 – 2022: RSS South West Local Group Meeting Programmes.