Publich health research

APHID

Title: A novel way to understand and communicate the burden of Antipsychotic Prescribing for Adults across Specialist Intellectual Disability Services in England and Wales
Chief Investigator: Professor Rohit Shankar, Faculty of Health, University of Plymouth
CycEDel-IC
Title: Does supine Cycle Ergometry delivered within 48 hours of mechanical ventilation, reduce the occurrence of Delirium in critICally ill patients and what is the optimal approach to implementing the intervention?
Chief Investigator: Jacqueline Bennion

D-PACT 2

Title: Realist informed mixed methods evaluation of the Dementia-Personalised Aligned Care Team intervention (D-PACT): a complex intervention for individuals with dementia and carers
Chief Investigator: Professor Richard Byng, Faculty of Health, University of Plymouth

ENRICH

Title: Randomised, Phase II open label study of Rituximab/Ibritinib vs Rituximab/Chemo in older patients with mantle cell lymphoma
Chief Investigator: Dr David Lewis, University Hospitals Plymouth NHS Trust
ERASE
Title: Evaluating the efficacy of Remdesivir for the improvement of lung function, perfusion, and symptom profile in long-covid patients.
Chief Investigator: Dr Mark Faghy, University of Derby

MCL Biobank

Title: Establishing a biobank and database as a national resource for characterising indolent and aggressive forms of mantle cell lymphoma.
Chief Investigator: Professor Simon Rule, University Hospitals Plymouth NHS Trust

MIRAGE

Title: Functional imagery training to reduce alcohol-related harm in patients with alcohol-related liver disease: a pilot randomised trial.
Chief Investigator: Dr Ashwin Dhanda, University Hospitals Plymouth NHS Trust

Oasis II

Title: A randomized phase II trial evaluating Ibrutinib plus CD20 Ab and Ibrutinib-Venetoclax plus CD20 Ab in patients with untreated mantle cell lymphoma.
Chief Investigator: Professor Steven Le Gouill, Institut Curie – Paris
Associate Coordinating Investigator: Dr David Lewis, University Hospitals Plymouth NHS Trust

OBtAIN-PD

Title: Developing an occupation-based complex intervention for living well with anxiety in Parkinson's.
Chief Investigator: Chris Lovegrove, Royal Devon & Exeter NHS Foundation Trust/ University of Plymouth

PD COVID-19

Title: To understand the outcome and mortality of hospital admission with COVID-19 in people with Parkinson’s disease and atypical parkinsonian syndromes (PD/APS), to inform patients and future design of health, social care and charity services.
Chief Investigator: Professor Camille Carroll, Faculty of Health, University of Plymouth

RECAP

Title: Older people with intellectual disabilities and epilepsy – recognising and correcting anticholinergic inducing polypharmacy
Chief Investigator: Professor Rohit Shankar, Faculty of Health, University of Plymouth

REFINE

Title: Neuropsychiatric Research Register for people with Intellectual Disabilities and Epilepsy
Chief Investigator: Professor Rohit Shankar, Faculty of Health, University of Plymouth

RESOLVE

Title: Reducing SteatOsis Prior to Liver Resection – A feasibility multi-centre randomised controlled trial to test if a pre-operative two-week very low-calorie diet with dietitian education and support reduces intra-operative blood loss and improves post-operative outcomes following liver surgery, compared with a control group
Chief Investigator: Mr Somaiah Aroori, Faculty of Health, University of Plymouth
RETREAT
Title: Repurposing anti-retroviral drugs to treat NF2 related tumours
Chief Investigator: Professor Oliver Hanemann, Faculty of Health, University of Plymouth

STEPS 2

Title: The Efficacy of Peroneal Nerve Functional Electrical STimulation (FES) for the Reduction of Bradykinesia in Parkinson’s DiSease: An Assessor Blinded Randomised Controlled Trial
Chief Investigator: Professor Paul Taylor, Salisbury NHS Foundation Trust