Concept 3d illustration of coronavirus COVID-19 disease

Trial status: closed to recruitment

ERASE-LC is funded by a research grant from Gilead Sciences for people with long COVID, sponsored by the University of Derby and managed by the University of Plymouth’s Peninsula Clinical Trials Unit (PenCTU) . Professor Mark Faghy (Professor in Clinical Exercise Science) is the Chief Investigator and will be leading the research.
One in ten people experience symptoms in the weeks, months and even years following a COVID-19 infection. These symptoms affect people in different ways and there is evidence that they impact physical and mental well-being and cognitive function. These collections of symptoms are called long COVID. Currently, there are no treatments available to address these issues, but anti-viral medications have been suggested as being potentially effective.
Remdesivir is an anti-viral medication used to treat people admitted to hospital with COVID-19. We don’t know if this works to reduce the symptoms of long COVID and before we conduct a large study to investigate this we need to see if a smaller number of participants are able to tolerate the study processes and the drug. The information gathered from this study will be used to inform the design of a larger future trial, which will determine whether Remdesivir can be used as a treatment for long COVID.
 
 

Study progress

  • 8 participants were recruited at Exeter in May and the final eleventh wave of Derby participants received their treatment w/c 12 May.
  • Derby closed to recruitment on 25 April 2025 with 53 recruits.
  • The first participant at Exeter and the tenth wave of Derby participants received their treatment w/c 28 April 2025.
  • University of Derby: https://www.derby.ac.uk/research/showcase/long-covid-research/
  • BBC News: https://www.bbc.co.uk/news/articles/ce822z9grjpo
  • 7 participants were recruited to the trial in April 2025, including the first patient at Exeter.
  • Exeter site opened to recruitment on 26 March 2025
  • 10 participants recruited at Derby in March 2025 (48 total)
  • The ninth wave of six participants received their treatment at Derby w/c 31 March 2025
  • Exeter site opened to recruitment on 26 March 2025
  • ITV News: 'Not forgotten': Fresh hope for long Covid sufferers, five years on from pandemic, March 2025
  • Expressions of interest for Derby paused on 11 March 2025
  • The sixth, seventh and eighth waves of 12 participants received their treatment in February 2025
  • The fifth wave of six participants received their treatment at Derby w/c 27 January 2025
  • The fourth wave of four participants received their treatment at Derby w/c 20 January 2025
  • 23 participants recruited at Derby between December 2024 – January 2025
  • The third wave of six participants received their treatment at Derby w/c 2 December 2024
  • The second wave of four participants received their treatment at Derby w/c 4 November 2024
  • Two participants recruited at Derby in November 2024
  • The first wave of four participants received their treatment at Derby w/c 28 October 2024
  • First 13 participants recruited at Derby in October 2024
 
 

PenCTU Staff