Professor Oliver Hanemann
Profiles

Professor Oliver Hanemann

Chair in Clinical Neurobiology

Peninsula Medical School (Faculty of Health)

Professor Oliver Hanemann can be contacted through arrangement with our Press Office, to speak to the media on these areas of expertise.
  • Cancer
  • Neurofibromatosis
  • Motor neurone disease
  • Oncology
  • Brain tumour
  • Neurology
  • Neuroscience
  • Clinical trials
  • Experimental methods
  • Laboratory methods
  • Medical/pathological research
  • Quantitative research
Biography

Biography

Chair of Clinical Neurobiology
Plymouth University Peninsula School of Medicine and Dentistry
Neurology Consultant
Plymouth Hospital NHS Trust 

Qualifications

I trained at Medical School in Hamburg, Glasgow, Johns Hopkins and Harvard. After a DFG research fellowship in molecular neurobiology, in which I cloned the myelin protein PMP22 together with P Spreyer, I was neurology registrar at Medical School in Duesseldorf with Prof Freund. During that period I participated in resolving gene-defect and pathogenesis of the most frequent hereditary neuropathy CMT1A, became lecturer for Neurology and Neurobiology and honorary consultant at that department in 1998 and started work on benign glial tumours. From 2000 I was consultant incl. clinical lead and senior lecturer at the medical school in Ulm with Prof Ludolph continuing my work on benign glia tumours and neuropathies focussing more on motor neuropathies. During that time I was also trained as a medical geneticist. In 2005 I became chair of clinical neurobiology at the Peninsula medical school establishing clinical neurobiology research and administering different independent researcher groups. I successfully bridge basic and clinical sciences. I have been Associate Medical Director for R&D Plymouth Hospital NHS Trust and and Academic lead department of Neurology PHNT

My new role at PU PSMD is Director of the Institute for Translational and Stratified Medicine where my remit is to champion research across traditional boundaries and focus on world-leading research.

Roles on external bodies

Nationally I am neurology lead in the Peninsula Neurooncology network, member NCRI brain tumour group and DeNDRON, (currently research director MND in the SW) member of scientific advisory boards (e.g. CTF, Lord Dowding Fund, Brain Research Trust), member of the council of the British Neuro-Oncology Society (BNOS). I am reviewer for more than 17 international journals including Brain, Cancer Res, Oncogene and Human Mol Gen, and reviewer for a variety of granting agencies incl Wellcome, MRC, CR-UK and DFG.

Key publications

Li W, You L, Cooper J, Schiavon G, Pepe-Caprio A, Zhou L, Ishii R, Giovannini M, Hanemann CO & Long SB (2010) 'Merlin/NF2 Suppresses Tumorigenesis by Inhibiting the E3 Ubiquitin Ligase CRL4(DCAF1) in the Nucleus' CELL 140, (4) 477-490 Author Site , DOI
Ammoun S, Flaiz C, Ristic N, Schuldt J & Hanemann CO (2008) 'Dissecting and targeting the growth factor-dependent and growth factor-independent extracellular signal-regulated kinase pathway in human schwannoma' Cancer Res 68, (13) 5236-5245 Author Site , DOI
Flaiz C, Utermark T, Parkinson DB, Poetsch A & Hanemann CO (2008) 'Impaired intercellular adhesion and immature adherens junctions in merlin-deficient human primary schwannoma cells' Glia 56, (5) 506-515 Author Site , DOI
Ammoun S, Schmid MC, Zhou L, Ristic N, Ercolano E, Hilton DA, Perks CM & Hanemann CO (2012) 'The role of insulin-like growth factors signaling in merlin-deficient human schwannomas. Ammoun S, Schmid MC, Ristic N, Zhou L, Hilton D, Ercolano E, Carroll C, Hanemann CO. Glia. 2012 Nov;60(11):1721-33. doi: 10.1002/glia.22391. Epub 2012 Jul 20' Glia
Ammoun S, Cunliffe CH, Allen J, Chiriboga L, Giancotti FG, Zagzag D, Hanemann CO & Karajannis MA (2010) 'ErbB/HER receptor activation and preclinical efficacy of lapatinib in vestibular schwannoma' Neuro Oncol. 8, (12) 834-43
Ammoun S, Cunliffe CH, Allen JC, Chiriboga L, Giancotti FG, Zagzag D, Hanemann CO & Karajannis MA (2010) 'ErbB/HER receptor activation and preclinical efficacy of lapatinib in vestibular schwannoma' Neuro Onc 12, 834-843
View all publications
Teaching

Teaching

Staff serving as external examiners

Involved in research SSU's, case units, lectures
External PhD examiner at: University of Exeter, University of Portsmouth, University Cardiff, Universit ät Jena, Universit ät Ulm

Research

Research

Research interests

My own focus is on neuromuscular disease esp. motor neuron disease and neurooncology. I supervised more than 15 PhD students quite a few finished with distinction and started a career in academia. Our current work on motor neuron disease is mainly clinical and includes genotype-phenotype analysis and clinical trials. In neurooncology we focus on cell biology studies to find and validate new therapeutic targets as there is a great medical need to find new treatments (summarized in Hanemann 2008, Ammoun and Hanemann 2011). Following our aim to work translational I also look after many patients with these diseases as a honorary consultant.

Research degrees awarded to supervised students

6 Phd's and 3 MD's finished successfully, 3 co-supervised successfully, 2 current

Grants & contracts

Over 2.1 Million £ previously excluding FEC. Currently Action Medical Research, Brain tumour charities, Dr Hadwen Trust and Samantha Dickson Brain Tumour Trust

Publications

Publications

Key publications

Li W, You L, Cooper J, Schiavon G, Pepe-Caprio A, Zhou L, Ishii R, Giovannini M, Hanemann CO & Long SB (2010) 'Merlin/NF2 Suppresses Tumorigenesis by Inhibiting the E3 Ubiquitin Ligase CRL4(DCAF1) in the Nucleus' CELL 140, (4) 477-490 Author Site , DOI
Ammoun S, Flaiz C, Ristic N, Schuldt J & Hanemann CO (2008) 'Dissecting and targeting the growth factor-dependent and growth factor-independent extracellular signal-regulated kinase pathway in human schwannoma' Cancer Res 68, (13) 5236-5245 Author Site , DOI
Flaiz C, Utermark T, Parkinson DB, Poetsch A & Hanemann CO (2008) 'Impaired intercellular adhesion and immature adherens junctions in merlin-deficient human primary schwannoma cells' Glia 56, (5) 506-515 Author Site , DOI
Ammoun S, Schmid MC, Zhou L, Ristic N, Ercolano E, Hilton DA, Perks CM & Hanemann CO (2012) 'The role of insulin-like growth factors signaling in merlin-deficient human schwannomas. Ammoun S, Schmid MC, Ristic N, Zhou L, Hilton D, Ercolano E, Carroll C, Hanemann CO. Glia. 2012 Nov;60(11):1721-33. doi: 10.1002/glia.22391. Epub 2012 Jul 20' Glia
Ammoun S, Cunliffe CH, Allen J, Chiriboga L, Giancotti FG, Zagzag D, Hanemann CO & Karajannis MA (2010) 'ErbB/HER receptor activation and preclinical efficacy of lapatinib in vestibular schwannoma' Neuro Oncol. 8, (12) 834-43
Ammoun S, Cunliffe CH, Allen JC, Chiriboga L, Giancotti FG, Zagzag D, Hanemann CO & Karajannis MA (2010) 'ErbB/HER receptor activation and preclinical efficacy of lapatinib in vestibular schwannoma' Neuro Onc 12, 834-843

Key publications are highlighted

Journals
Articles
Jungwirth G, Hanemann CO, Dunn IF & Herold-Mende C (2023) 'Preclinical Models of Meningioma' 199-211 , DOI
Albanese A, Ludolph AC, McDermott CJ, Corcia P, Van Damme P, Van den Berg LH, Hardiman O, Rinaldi G, Vanacore N & Dickie B (2022) 'Tauroursodeoxycholic acid in patients with amyotrophic lateral sclerosis: The TUDCA-ALS trial protocol' Frontiers in Neurology 13, , DOI Open access
Laraba L, Hillson L, de Guibert JG, Hewitt A, Jaques MR, Tang TT, Post L, Ercolano E, Rai G & Yang SM (2022) 'Inhibition of YAP/TAZ-driven TEAD activity prevents growth of NF2-null schwannoma and meningioma' Brain , DOI Open access
Abdelrahman A, Negroni C, Sahm F, Adams CL, Urbanic-Purkart T, Khalil M, Vergura R, Morelli C & Hanemann CO (2022) 'miR-497 and 219 in blood aid meningioma classification' Journal of Neuro-Oncology 160, (1) 137-147 , DOI
Plotkin SR, Messiaen L, Legius E, Pancza P, Avery RA, Blakeley JO, Babovic-Vuksanovic D, Ferner R, Fisher MJ & Friedman JM (2022) 'Updated diagnostic criteria and nomenclature for neurofibromatosis type 2 and schwannomatosis: An international consensus recommendation' Genetics in Medicine , DOI Open access
Millward CP, Armstrong TS, Barrington H, Bell S, Brodbelt AR, Bulbeck H, Crofton A, Dirven L, Georgious T & Grundy PL (2022) 'Development of ‘Core Outcome Sets’ for Meningioma in Clinical Studies (The COSMIC Project): protocol for two systematic literature reviews, eDelphi surveys and online consensus meetings' BMJ Open 12, (5) , DOI Open access
Young CA, Mills R, Langdon D, Sharrack B, Majeed T, Kalra S, Footitt D, Rog D, Harrower T & Nicholas R (2022) 'The four self-efficacy trajectories among people with multiple sclerosis: Clinical associations and implications' Journal of the Neurological Sciences 436, 120188-120188 , DOI
Kliest T, Van Eijk RPA, Al-Chalabi A, Albanese A, Andersen PM, Amador MDM, BrÅthen G, Brunaud-Danel V, Brylev L & Camu W (2022) 'Clinical trials in pediatric ALS: a TRICALS feasibility study' Amyotrophic lateral sclerosis & frontotemporal degeneration 1-8 , DOI Open access
Turner MR (2022) 'Diagnosing ALS: the Gold Coast criteria and the role of EMG' Practical Neurology , DOI
Maze EA, Agit B, Reeves S, Hilton DA, Parkinson DB, Laraba L, Ercolano E, Kurian KM, Hanemann CO & Belshaw RD (2021) 'Human endogenous retrovirus type K promotes proliferation and confers sensitivity to anti-retroviral drugs in Merlin-negative schwannoma and meningioma' Cancer Research , DOI Open access
Bettegowda C, Upadhayaya M, Evans DG, Kim A, Mathios D & Hanemann CO (2021) 'Genotype-Phenotype Correlations in Neurofibromatosis and Their Potential Clinical use' Neurology 10.1212/WNL.00000000-10.1212/WNL.00000000 , DOI Open access
Hanemann C (2021) 'REiNS: Genotype-Phenotype Correlations in Neurofibromatosis and Their Potential Clinical use' Neurology , DOI Open access
Sofela AA, McGavin L, Whitfield PC & Hanemann CO (2021) 'Biomarkers for differentiating grade II meningiomas from grade I: a systematic review' British Journal of Neurosurgery 1-7 , DOI Open access
Legius E, Messiaen L, Wolkenstein P, Pancza P, Avery RA, Berman Y, Blakeley J, Babovic-Vuksanovic D, Cunha KS & Ferner R (2021) 'Revised diagnostic criteria for neurofibromatosis type 1 and Legius syndrome: an international consensus recommendation' Genetics in Medicine 23, (8) 1506-1513 , DOI Open access
Cooper J, Xu Q, Zhou L, Pavlovic M, Ojeda V, Moulick K, de Stanchina E, Poirier JT, Zauderer M & Rudin CM (2021) 'Correction: Combined Inhibition of NEDD8-activating Enzyme and mTOR Suppresses NF2 Loss–driven Tumorigenesis' Molecular Cancer Therapeutics 20, (2) 450-450 , DOI
Young CA, McDermott CJ, Williams TL, Ealing J, Majeed T, Al-Chalabi A, Dick DJ, Talbot K, Harrower T & Pinto A (2021) 'Measuring coping in people with amyotrophic lateral sclerosis using the Coping Index-ALS: A patient derived, Rasch compliant scale' Journal of the Neurological Sciences 421, 117285-117285 , DOI Open access
Sofela AA, Hilton DA, Ammoun S, Baiz D, Adams CL, Ercolano E, Jenkinson MD, Kurian KM, Teo M & Whitfield PC (2021) 'Fibulin-2: A Novel Biomarker for Differentiating Grade II from Grade I Meningiomas' International Journal of Molecular Sciences 22, (2) 560-560 , DOI Open access
Dunn J, Lenis VP, Hilton DA, Warta R, Herold-Mende C, Hanemann CO & Futschik ME (2020) 'Integration and Comparison of Transcriptomic and Proteomic Data for Meningioma' Cancers 12, (11) 3270-3270 , DOI Open access
Negroni C, Hilton DA, Ercolano E, Adams CL, Kurian KM, Baiz D & Hanemann CO (2020) 'GATA-4, a potential novel therapeutic target for high-grade meningioma, regulates miR-497, a potential novel circulating biomarker for high-grade meningioma' EBioMedicine 59, 102941-102941 , DOI Open access
Bracher M, Pilkington GJ, Hanemann CO & Pilkington K (2020) 'A Systematic Approach to Review of in vitro Methods in Brain Tumour Research (SAToRI-BTR): Development of a Preliminary Checklist for Evaluating Quality and Human Relevance' Frontiers in Bioengineering and Biotechnology 8, , DOI Open access
Lyons Rimmer J, Ercolano E, Baiz D, Makhija M, Berger A, Sells T, Stroud S, Hilton D, Adams CL & Hanemann CO (2020) 'The Potential of MLN3651 in Combination with Selumetinib as a Treatment for Merlin-Deficient Meningioma' Cancers 12, (7) 1744-1744 , DOI Open access
Young CA, Mills R, Al-Chalabi A, Burke G, Chandran S, Dick DJ, Ealing J, Hanemann CO, Harrower T & Mcdermott CJ (2020) 'Measuring quality of life in ALS/MND: validation of the WHOQOL-BREF' Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 21, (5-6) 364-372 , DOI Open access
Palomo-Irigoyen M, Pérez-Andrés E, Iruarrizaga-Lejarreta M, Barreira-Manrique A, Tamayo-Caro M, Vila-Vecilla L, Moreno-Cugnon L, Beitia N, Medrano D & Fernández-Ramos D (2020) 'HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis' Journal of Clinical Investigation 130, (7) 3848-3864 , DOI Open access
Adams CL, Ercolano E, Ferluga S, Sofela A, Dave F, Negroni C, Kurian KM, Hilton DA & Hanemann CO (2020) 'A Rapid Robust Method for Subgrouping Non-NF2 Meningiomas According to Genotype and Detection of Lower Levels of M2 Macrophages in AKT1 E17K Mutated Tumours' International Journal of Molecular Sciences 21, (4) 1273-1273 , DOI Open access
Edge R, Mills R, Tennant A, Diggle PJ & Young CA (2020) 'Correction to: Do pain, anxiety and depression influence quality of life for people with amyotrophic lateral sclerosis/motor neuron disease? A national study reconciling previous conflicting literature' Journal of Neurology 267, (3) 616-617 , DOI Open access
Ferluga S, Baiz D, Hilton DA, Adams CL, Ercolano E, Dunn J, Bassiri K, Kurian KM & Hanemann CO (2020) 'Constitutive activation of the EGFR–STAT1 axis increases proliferation of meningioma tumor cells' Neuro-Oncology Advances 2, (1) , DOI Open access
Edge R, Mills R, Tennant A, Diggle PJ & Young CA (2019) 'Do pain, anxiety and depression influence quality of life for people with amyotrophic lateral sclerosis/motor neuron disease? A national study reconciling previous conflicting literature' Journal of Neurology 267, (3) 607-615 , DOI Open access
Nassiri F, Mamatjan Y, Suppiah S, Badhiwala JH, Mansouri S, Karimi S, Saarela O, Poisson L, Gepfner-Tuma I & Schittenhelm J (2019) 'DNA methylation profiling to predict recurrence risk in meningioma: development and validation of a nomogram to optimize clinical management' Neuro-Oncology 21, (7) 901-910 , DOI Open access
Young CA, Ealing J, McDermott C, Williams T, Al-Chalabi A, Majeed T, Burke G, Pinto A, Dick D & Talbot K (2019) 'The relationships between symptoms, disability, perceived health and quality of life in amyotrophic lateral sclerosis/motor neuron disease' Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 20, (5-6) 317-327 , DOI Open access
Shefner JM, Cudkowicz ME, Hardiman O, Cockroft BM, Lee JH, Malik FI, Meng L, Rudnicki SA, Wolff AA & Andrews JA (2019) 'A phase III trial of tirasemtiv as a potential treatment for amyotrophic lateral sclerosis' Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 20, (7-8) 584-594 , DOI Open access
Mills SJ, Radon MR, Baird RD, Hanemann CO, Keatley D, Lewis J, Pollock J, Sanghera P, Santarius T & Whitfield G (2019) 'Utilization of volumetric magnetic resonance imaging for baseline and surveillance imaging in Neuro-oncology' The British Journal of Radiology 20190059-20190059 , DOI Open access
Halliday D, Emmanouil B, Vassallo G, Lascelles K, Nicholson J, Chandratre S, Anand G, Wasik M, Pretorius P & Evans DG (2019) 'Trends in phenotype in the English paediatric neurofibromatosis type 2 cohort stratified by genetic severity' Clinical Genetics: an international journal of genetics and molecular medicine 96, (2) 151-162 , DOI Open access
Hanemann CO, Ammoun S, Evans G, Hilton DA, Streeter A & Hayward C (2019) 'Phase 0 trial investigating the intra-tumoural concentration and activity of Sorafenib in Neurofibromatosis type 2' Journal of Neurology, Neurosurgery and Psychiatry , DOI Open access
Brastianos PK, Galanis E, Butowski N, Chan JW, Dunn IF, Goldbrunner R, Herold-Mende C, Ippen FM, Mawrin C & McDermott MW (2019) 'Advances in multidisciplinary therapy for meningiomas' Neuro-Oncology 21, (Supplement_1) i18-i31 , DOI
Huang RY, Bi WL, Griffith B, Kaufmann TJ, la Fougère C, Schmidt NO, Tonn JC, Vogelbaum MA, Wen PY & Aldape K (2019) 'Imaging and diagnostic advances for intracranial meningiomas' Neuro-Oncology 21, (Supplement_1) i44-i61 , DOI
Nassiri F, Price B, Shehab A, Au K, Cusimano MD, Jenkinson MD, Jungk C, Mansouri A, Santarius T & Suppiah S (2019) 'Life after surgical resection of a meningioma: a prospective cross-sectional study evaluating health-related quality of life' Neuro-Oncology 21, (Supplement_1) i32-i43 , DOI
Suppiah S, Nassiri F, Bi WL, Dunn IF, Hanemann CO, Horbinski CM, Hashizume R, James CD, Mawrin C & Noushmehr H (2019) 'Molecular and translational advances in meningiomas' Neuro-Oncology 21, (Supplement_1) i4-i17 , DOI Open access
Dunn J, Ferluga S, Sharma V, Futschik M, Hilton DA, Adams CL, Lasonder E & Hanemann CO (2018) 'Proteomic analysis discovers the differential expression of novel proteins and phosphoproteins in meningioma including NEK9, HK2 and SET and deregulation of RNA metabolism' EBioMedicine Author Site , DOI Open access
Hanemann CO, Emmanouil B, Houston R, May A, Ramsden JD, Halliday D, Parry A & Mackeith S (2018) 'Progression of Hearing Loss in Neurofibromatosis Type 2 According to Genetic Severity' The Laryngoscope , DOI Open access
Collord G, Tarpey P, Kurbatova N, Martincorena I, Moran S, Castro M, Nagy T, Bignell G, Maura F & Young MD (2018) 'An integrated genomic analysis of anaplastic meningioma identifies prognostic molecular signatures' Scientific Reports 8, (1) 13537-13537 Author Site , DOI Open access
Baiz D, Negroni C, Ferluga S, Ercolano E, Adams C & Hanemann OC (2018) 'PO-511 High miR-9 levels represent a novel prognostic biomarker to predict development of malignant meningioma' ESMO Open 3, A430-A430 , DOI Open access
Milinis K, Tennant A, Mills RJ, Al-Chalabi A, Burke G, Dick DJ, Ealing J, Hanemann CO, Harrower T & McDermott CJ (2018) 'Development and validation of Spasticity Index-Amyotrophic Lateral Sclerosis' Acta Neurologica Scandinavica Author Site , DOI Open access
Stepanova DS, Semenova G, Kuo Y-M, Andrews AJ, Ammoun S, Hanemann CO & Chernoff J (2017) 'An essential role for the tumor suppressor Merlin in regulating fatty acid synthesis' Cancer Research Author Site , DOI Open access
Provenzano L, Ryan Y, Hilton DA, Lyons-Rimmer J, Dave F, Maze EA, Adams CL, Rigby-Jones R, Ammoun S & Hanemann CO (2017) 'Cellular prion protein (PrPC) in the development of Merlin-deficient tumours' Oncogene , DOI Open access
Button RW, Roberts SL, Willis TL, Hanemann CO & Luo S (2017) 'Accumulation of autophagosomes confers cytotoxicity' Journal of Biological Chemistry 13599-13614 , DOI Open access
Cooper J, Xu Q, Zhou L, Pavlovic M, Ojeda V, Moulick K, de Stanchina E, Poirier JT, Zauderer M & Rudin CM (2017) 'Combined Inhibition of NEDD8-Activating Enzyme and mTOR Suppresses NF2 Loss-Driven Tumorigenesis' Molecular Cancer Therapeutics molcanther.0821.2016-molcanther.0821.2016 , DOI Open access
Bassiri K, Ferluga S, Sharma V, Syed N, Adams CL, Lasonder E & Hanemann CO (2017) 'Global Proteome and Phospho-proteome Analysis of Merlin-deficient Meningioma and Schwannoma Identifies PDLIM2 as a Novel Therapeutic Target' EBioMedicine , DOI Open access
McGeachan AJ, Hobson EV, Al-Chalabi A, Stephenson J, Chandran S, Crawley F, Dick D, Donaghy C, Ellis CM & Gorrie G (2016) 'A multicentre evaluation of oropharyngeal secretion management practices in amyotrophic lateral sclerosis' Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 18, (1-2) 1-9 , DOI
Hanemann CO, Blakeley JO, Nunes FP, Robertson K, Stemmer-Rachamimov A, Mautner V, Kurtz A, Ferguson M, Widemann BC & Evans DG (2016) 'Current status and recommendations for biomarkers and biobanking in neurofibromatosis' Neurology 87, (7 Supplement 1) S40-S48 , DOI Open access
Ahlawat S, Fayad LM, Khan MS, Bredella MA, Harris GJ, Evans DG, Farschtschi S, Jacobs MA, Chhabra A & Salamon JM (2016) 'Current whole-body MRI applications in the neurofibromatoses' Neurology 87, (7 Supplement 1) S31-S39 , DOI Open access
Walsh KS, Janusz J, Wolters PL, Martin S, Klein-Tasman BP, Toledo-Tamula MA, Thompson HL, Payne JM, Hardy KK & de Blank P (2016) 'Neurocognitive outcomes in neurofibromatosis clinical trials' Neurology 87, (7 Supplement 1) S21-S30 , DOI Open access
Plotkin SR, Davis SD, Robertson KA, Akshintala S, Allen J, Fisher MJ, Blakeley JO, Widemann BC, Ferner RE & Marcus CL (2016) 'Sleep and pulmonary outcomes for clinical trials of airway plexiform neurofibromas in NF1' Neurology 87, (7 Supplement 1) S13-S20 , DOI Open access
Hanemann CO, Wolters PL, Martin S, Merker VL, Tonsgard JH, Soloman SE, Baldwin A, Bergner AL, Walsh K & Thompson HL (2016) 'Patient-reported outcomes of pain and physical functioning in neurofibromatosis clinical trials' Neurology 87, (7 Suppl 1) S4-S12 , DOI Open access
Zeissler M-L, Eastwood J, McCorry K, Hanemann OC, Zajicek JP & Carroll CB (2016) 'Delta-9-tetrahydrocannabinol protects against MPP+ toxicity in SH-SY5Y cells by restoring proteins involved in mitochondrial biogenesis' Oncotarget , DOI Open access
McDermott CJ, Bradburn MJ, Maguire C, Cooper CL, Baird WO, Baxter SK, Cohen J, Cantrill H, Dixon S & Ackroyd R (2016) 'DiPALS: Diaphragm Pacing in patients with Amyotrophic Lateral Sclerosis – a randomised controlled trial' Health Technology Assessment 20, (45) 1-186 , DOI Open access
Hilton DA, Shivane A, Kirk L, Bassiri K, Enki DG & Hanemann CO (2015) 'Activation of multiple growth factor signalling pathways is frequent in meningiomas' Neuropathology 36, (3) 250-261 , DOI Open access
Zhou L, Lyons-Rimmer J, Ammoun S, Müller J, Lasonder E, Sharma V, Ercolano E, Hilton D, Taiwo I & Barczyk M (2015) 'The scaffold protein KSR1, a novel therapeutic target for the treatment of Merlin-deficient tumors' Oncogene 35, (26) 3443-3453 , DOI Open access
Hilton DA, Shivane A, Kirk L, Bassiri K & Hanemann CO (2015) 'PO76GROWTH FACTOR SIGNALLING PATHWAYS IN MENINGIOMAS IS COMMON AND PARTLY DEPENDS ON SUBTYPE ALLOWING FOR STRATIFICATION' Neuro-Oncology 17, (suppl 8) viii14.1-viii14 , DOI
(2015) 'Safety and efficacy of diaphragm pacing in patients with respiratory insufficiency due to amyotrophic lateral sclerosis (DiPALS): a multicentre, open-label, randomised controlled trial' The Lancet Neurology 14, (9) 883-892 , DOI Open access
Hexter A, Jones A, Joe H, Heap L, Smith MJ, Wallace AJ, Halliday D, Parry A, Taylor A & Raymond L (2015) 'Clinical and molecular predictors of mortality in neurofibromatosis 2: a UK national analysis of 1192 patients' Journal of Medical Genetics 52, (10) 699-705 , DOI
(2015) 'Gastrostomy in patients with amyotrophic lateral sclerosis (ProGas): a prospective cohort study' The Lancet Neurology 14, (7) 702-709 , DOI Open access
Rauen KA, Huson SM, Burkitt-Wright E, Evans DG, Farschtschi S, Ferner RE, Gutmann DH, Hanemann CO, Kerr B & Legius E (2015) 'Recent Developments in Neurofibromatoses and RASopathies: Management, Diagnosis and Current and Future Therapeutic Avenues' AMERICAN JOURNAL OF MEDICAL GENETICS PART A 167, (1) 1-10 Author Site , DOI
Ammoun S, Schmid MC, Zhou L, Hilton DA, Barczyk M & Hanemann CO (2015) 'The p53/mouse double minute 2 homolog complex deregulation in merlin-deficient tumours' Mol Oncol 9, (1) 236-248 Author Site , DOI
Ammoun S, Provenzano L, Zhou L, Schmid MC & Hanemann CO (2014) 'IDENTIFICATION AND TARGETING PATHWAYS INVOLVED IN THE DEVELOPMENT OF MERLIN-DEFICIENT TUMOURS' ANTICANCER RESEARCH 34, (10) 5805-5805 Author Site
Provenzano L, Ammoun S & Hanemann CO (2014) 'THE ROLE OF CELLULAR PRION PROTEIN IN SCHWANNOMA AND OTHER MERLIN-DEFICIENT TUMOURS' ANTICANCER RESEARCH 34, (10) 6123-6123 Author Site
Button RW, Lin F, Ercolano E, Vincent JH, Hu B, Hanemann CO & Luo S (2014) 'Artesunate induces necrotic cell death in schwannoma cells' Cell Death Dis 5, (10) Author Site , DOI Open access
Hanemann CO, Hilton D, Shivane A & Turner L (2014) 'P06.02 * ACTIVATION OF MULTIPLE GROWTH FACTOR SIGNALLING PATHWAYS IS FREQUENT IN MENINGIOMAS' Neuro-Oncology 16, (suppl 2) ii45-ii45 , DOI
Li W, Cooper J, Zhou L, Yang C, Erdjument-Bromage H, Zagzag D, Snuderl M, Ladanyi M, Hanemann CO & Zhou P (2014) 'Merlin/NF2 loss-driven tumorigenesis linked to CRL4(DCAF1)-mediated inhibition of the hippo pathway kinases Lats1 and 2 in the nucleus' Cancer Cell 26, (1) 48-60 Author Site , DOI
Ferner RE, Shaw A, Evans DG, McAleer D, Halliday D, Parry A, Raymond FL, Durie-Gair J, Hanemann CO & Hornigold R (2014) 'Longitudinal evaluation of quality of life in 288 patients with neurofibromatosis 2' JOURNAL OF NEUROLOGY 261, (5) 963-969 Author Site , DOI Open access
Hilton DA & Hanemann CO (2014) 'Schwannomas and Their Pathogenesis' BRAIN PATHOLOGY 24, (3) 205-220 Author Site , DOI
Hilton DA & Hanemann CO (2014) 'Schwannomas and their pathogenesis' Brain Pathol 24, (3) 205-220 Author Site , DOI
Widemann BC, Acosta MT, Ammoun S, Belzberg AJ, Bernards A, Blakeley J, Bretscher A, Cichowski K, Clapp DW & Dombi E (2014) 'CTF Meeting 2012: Translation of the Basic Understanding of the Biology and Genetics of NF1, NF2, and Schwannomatosis Toward the Development of Effective Therapies' AMERICAN JOURNAL OF MEDICAL GENETICS PART A 164, (3) 563-578 Author Site , DOI
Ammoun S, Provenzano L, Zhou L, Barczyk M, Evans K, Hilton DA, Hafizi S & Hanemann CO (2014) 'Axl/Gas6/NFκB signalling in schwannoma pathological proliferation, adhesion and survival' Oncogene 33, (3) 336-346 Author Site , DOI Open access
Hobson EV, McGeachan A, Al-Chalabi A, Chandran S, Crawley F, Dick D, Donaghy C, Ealing J, Ellis CM & Gorrie G (2013) 'Management of sialorrhoea in motor neuron disease: A survey of current UK practice' AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION 14, (7-8) 521-527 Author Site , DOI
Plotkin SR, Blakeley JO, Dombi E, Fisher MJ, Hanemann CO, Walsh KS, Wolters PL & Widemann BC (2013) 'Achieving consensus for clinical trials The REiNS International Collaboration' NEUROLOGY 81, (21) S1-S5 Author Site , DOI
Plotkin SR, Blakeley JO, Dombi E, Fisher MJ, Hanemann CO, Walsh KS, Wolters PL & Widemann BC (2013) 'Achieving consensus for clinical trials: the REiNS International Collaboration' Neurology 81, (21 Suppl 1) S1-S5 Author Site , DOI
Widemann BC, Blakeley JO, Dombi E, Fisher MJ, Hanemann CO, Walsh KS, Wolters PL & Plotkin SR (2013) 'Conclusions and future directions for the REiNS International Collaboration' NEUROLOGY 81, (21) S41-S44 Author Site , DOI
Widemann BC, Blakeley JO, Dombi E, Fisher MJ, Hanemann CO, Walsh KS, Wolters PL & Plotkin SR (2013) 'Conclusions and future directions for the REiNS International Collaboration' Neurology 81, (21 Suppl 1) S41-S44 Author Site , DOI
Plotkin SR, Blakeley JO, Dombi E, Fisher MJ, Hanemann CO, Walsh KS, Wolters PL & Widemann BC (2013) 'Achieving consensus for clinical trials: the REiNS International Collaboration' Neurology 81, (21) S1-S5 , DOI
Zeissler ML, Eastwood J, Oliver Hanemann C, Zajicek J & Carroll C (2013) 'Δ9-TETRAHYDROCANNABINOL IS PROTECTIVE THROUGH PPARγ DEPENDENT MITOCHONDRIAL BIOGENESIS IN A CELL CULTURE MODEL OF PARKINSON'S DISEASE' J Neurol Neurosurg Psychiatry 84, (11) Author Site , DOI Open access
Rankin J, Short J, Turnpenny P, Castle B & Hanemann CO (2013) 'Medulloblastoma in a Patient With the PTPN11 p.Thr468Met Mutation' AMERICAN JOURNAL OF MEDICAL GENETICS PART A 161, (8) 2027-2029 Author Site , DOI
Allen C, Counsell C, Farrin A, Al-Chalabi A, Dickie B, Leigh PN, Murphy CL, Payan C, Reynolds G & Shaw P (2013) 'Lithium in patients with amyotrophic lateral sclerosis (LiCALS): a phase 3 multicentre, randomised, double-blind, placebo-controlled trial' LANCET NEUROLOGY 12, (4) 339-345 Author Site , DOI
Schulz A, Baader SL, Niwa-Kawakita M, Jung MJ, Bauer R, Garcia C, Zoch A, Schacke S, Hagel C & Mautner V-F (2013) 'Merlin isoform 2 in neurofibromatosis type 2-associated polyneuropathy' NATURE NEUROSCIENCE 16, (4) 426-U86 Author Site , DOI
Shivane A, Parkinson DB, Ammoun S & Hanemann CO (2013) 'Expression of c-Jun and Sox-2 in human schwannomas and traumatic neuromas' HISTOPATHOLOGY 62, (4) 651-656 Author Site , DOI
Plotkin SR, Blakeley JO, Evans DG, Hanemann CO, Hulsebos TJM, Hunter-Schaedle K, Kalpana GV, Korf B, Messiaen L & Papi L (2013) 'Update from the 2011 International Schwannomatosis Workshop: From genetics to diagnostic criteria' AMERICAN JOURNAL OF MEDICAL GENETICS PART A 161A, (3) 405-416 Author Site , DOI
Doddrell RDS, Dun X-P, Shivane A, Feltri ML, Wrabetz L, Wegner M, Sock E, Hanemann CO & Parkinson DB (2013) 'Loss of SOX10 function contributes to the phenotype of human Merlin-null schwannoma cells' Brain 136, (Pt 2) 549-563 Author Site , DOI Open access
Widemann BC, Blakeley JO, Dombi E, Fisher MJ, Hanemann CO, Walsh KS, Wolters PL & Plotkin SR (2013) 'Conclusions and future directions for the REiNS International Collaboration' Neurology 81, (21 Suppl 1) , DOI
Ammoun S, Schmid MC, Ristic N, Zhou L, Hilton D, Ercolano E, Carroll C & Hanemann CO (2012) 'The role of insulin-like growth factors signaling in merlin-deficient human schwannomas' Glia 60, (11) 1721-1733 Author Site , DOI Open access
Carroll CB, Zeissler M-L, Hanemann CO & Zajicek JP (2012) 'Δ<sup>9</sup>-tetrahydrocannabinol (Δ<sup>9</sup>-THC) exerts a direct neuroprotective effect in a human cell culture model of Parkinson's disease' Neuropathology and Applied Neurobiology 38, (6) 535-547 , DOI
Ammoun S, Schmid MC, Zhou L, Ristic N, Ercolano E, Hilton DA, Perks CM & Hanemann CO (2012) 'The role of insulin-like growth factors signaling in merlin-deficient human schwannomas. Ammoun S, Schmid MC, Ristic N, Zhou L, Hilton D, Ercolano E, Carroll C, Hanemann CO. Glia. 2012 Nov;60(11):1721-33. doi: 10.1002/glia.22391. Epub 2012 Jul 20' Glia
Zhou L & Hanemann CO (2012) 'Merlin, a multi-suppressor from cell membrane to the nucleus' FEBS Lett 586, (10) 1403-1408 Author Site , DOI
Ammoun S, Schmid MC, Zhou L, Ristic N, Ercolano E, Hilton DA, Perks CM & Hanemann CO (2012) 'Insulin-like growth factor-binding protein-1 (IGFBP-1) regulates human schwannoma proliferation, adhesion and survival' Oncogene 31, (13) 1710-1722 Author Site , DOI
Kalamarides M, Acosta MT, Babovic-Vuksanovic D, Carpen O, Cichowski K, Evans DG, Giancotti F, Hanemann CO, Ingram D & Lloyd AC (2012) 'Neurofibromatosis 2011: a report of the Children's Tumor Foundation annual meeting' Acta Neuropathol 123, (3) 369-380 Author Site , DOI Open access
Blakeley JO, Evans DG, Adler J, Brackmann D, Chen R, Ferner RE, Hanemann CO, Harris G, Huson SM & Jacob A (2012) 'Consensus recommendations for current treatments and accelerating clinical trials for patients with neurofibromatosis type 2' Am J Med Genet A 158A, (1) 24-41 Author Site , DOI
Zhou L, Ercolano E, Ammoun S, Schmid MC, Barczyk MA & Hanemann CO (2011) 'Merlin-deficient human tumors show loss of contact inhibition and activation of Wnt/β-catenin signaling linked to the PDGFR/Src and Rac/PAK pathways' Neoplasia 13, (12) 1101-1112 Author Site , DOI
Al-Chalabi A, Shaw PJ, Young CA, Morrison KE, Murphy C, Thornhill M, Kelly J, Steen IN, Leigh PN & UKMND-LiCALS (2011) 'Protocol for a double-blind randomised placebo-controlled trial of lithium carbonate in patients with amyotrophic lateral sclerosis (LiCALS) [Eudract number: 2008-006891-31]' BMC Neurol 11, Author Site , DOI Open access
Zhang H, Hilton DA, Hanemann CO & Zajicek J (2011) 'Cannabinoid receptor and N-acyl phosphatidylethanolamine phospholipase D--evidence for altered expression in multiple sclerosis' Brain Pathol 21, (5) 544-557 Author Site , DOI
Carroll CB, Zeissler M-L, Chadborn N, Gibson K, Williams G, Zajicek JP, Morrison KE & Hanemann CO (2011) 'Changes in iron-regulatory gene expression occur in human cell culture models of Parkinson's disease' Neurochem Int 59, (1) 73-80 Author Site , DOI Open access
Ammoun S, Schmid MC, Triner J, Manley P & Hanemann CO (2011) 'Nilotinib alone or in combination with selumetinib is a drug candidate for neurofibromatosis type 2' Neuro Oncol 13, (7) 759-766 Author Site , DOI
Ammoun S & Hanemann CO (2011) 'Emerging therapeutic targets in schwannomas and other merlin-deficient tumors' Nat Rev Neurol 7, (7) 392-399 Author Site , DOI
Zhang H, Hilton DA, Hanemann CO & Zajicek J (2011) 'Cannabinoid Receptor and N-acyl Phosphatidylethanolamine Phospholipase D-Evidence for Altered Expression in Multiple Sclerosis' Brain Pathol 5, 544-557
Carroll CB, Zeissler ML, Chadborn N, Gibson K, William G, Zajicek JP, Morrison KE & Hanemann CO (2011) 'Changes in iron-regulatory gene expression occur in human cell culture models of Parkinson's disease' Neurochem Int 59, 73-80
Cooper J, Li W, Schiavon, Pepe-Caprio A, Zhou L, Ishii A, Hanemann CO, Long SB, Erdjument-Bromage H & Zhou P (2011) 'Merlin/NF2 Functions Upstream of the Nuclear E3 Ubiquitin Ligase CRL4DCAF1 to Suppress Oncogenic Gene Expression' Scinece Siganlling 4,
Carroll C, Krolikowski K, Mukonoweshuro W, Jones J & Hanemann CO (2010) 'Unilateral cerebral hemisphere oedema as a peri-ictal phenomenon' J Neurol 257, (12) 2094-2096 Author Site , DOI
Carroll CB, Zeissler ML, Chadborn N, Gibson K, Williams GJ, Morrison KE, Zajicek JP & Hanemann CO (2010) 'Changes in Iron-Regulatory Gene Expression Occur in Human Cell Culture Models of PD' MOVEMENT DISORDERS 25, S628-S628 Author Site Open access
Ammoun S, Cunliffe CH, Allen J, Chiriboga L, Giancotti FG, Zagzag D, Hanemann CO & Karajannis MA (2010) 'ErbB/HER receptor activation and preclinical efficacy of lapatinib in vestibular schwannoma' Neuro Oncol. 8, (12) 834-43
Ammoun S, Cunliffe CH, Allen JC, Chiriboga L, Giancotti FG, Zagzag D, Hanemann CO & Karajannis MA (2010) 'ErbB/HER receptor activation and preclinical efficacy of lapatinib in vestibular schwannoma' Neuro Oncol 12, (8) 834-843 Author Site , DOI
Li W, You L, Cooper J, Schiavon G, Pepe-Caprio A, Zhou L, Ishii R, Giovannini M, Hanemann CO & Long SB (2010) 'Merlin/NF2 Suppresses Tumorigenesis by Inhibiting the E3 Ubiquitin Ligase CRL4(DCAF1) in the Nucleus' CELL 140, (4) 477-490 Author Site , DOI
George JS, Harikrishnan S, Ali I, Baresi R & Hanemann CO (2010) 'Acquired rippling muscle disease in association with myasthenia gravis' JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY 81, (1) 125-126 Author Site , DOI
Ammoun S, Ristic N, Matthies C, Hilton DA & Hanemann CO (2010) 'Targeting ERK1/2 activation and proliferation in human primary schwannoma cells with MEK1/2 inhibitor AZD6244' Neurobiol Dis 37, (1) 141-146 Author Site , DOI
Imam I, Ball S, Wright D & Hanemann CO (2010) 'The epidemiology of motor neurone disease in two counties in the southwest of England' Journal of Neurology Publisher Site
Ammoun S, Cunliffe CH, Allen JC, Chiriboga L, Giancotti FG, Zagzag D, Hanemann CO & Karajannis MA (2010) 'ErbB/HER receptor activation and preclinical efficacy of lapatinib in vestibular schwannoma' Neuro Onc 12, 834-843
Hilton DA, Ristic N & Hanemann CO (2009) 'Activation of ERK, AKT and JNK signalling pathways in human schwannomas in situ' Histopathology 55, (6) 744-749 Author Site , DOI
Imam I, Edwards S & Hanemann CO (2009) 'Aquired neuromyotonia following upper respiratory tract infection' Case J 2, 7952-7952 Open access
Imam I, Edwards S & Hanemann CO (2009) 'Acquired neuromyotonia following upper respiratory tract infection: a case report' Cases J 2, Author Site , DOI Open access
Imam I, Edwards S & Hanemann CO (2009) 'Acquired neuromyotonia following upper respiratory tract infection: A case report' Cases Journal 2, (9) , DOI
Flaiz C, Chernoff J, Ammoun S, Peterson JR & Hanemann CO (2009) 'PAK kinase regulates Rac GTPase and is a potential target in human schwannomas' Exp Neurol 218, (1) 137-144 Author Site , DOI
Flaiz C, Ammoun S, Biebl A & Hanemann CO (2009) 'Altered adhesive structures and their relation to RhoGTPase activation in merlin-deficient Schwannoma' Brain Pathol 19, (1) 27-38 Author Site , DOI
Widmer M, Hanemann CO & Zajicek J (2008) 'High concentrations of cannabinoids activate apoptosis in human U373MG glioma cells' J Neurosci Res 86, (14) 3212-3220 Author Site , DOI
Ammoun S, Flaiz C, Ristic N, Schuldt J & Hanemann CO (2008) 'Dissecting and targeting the growth factor-dependent and growth factor-independent extracellular signal-regulated kinase pathway in human schwannoma' Cancer Res 68, (13) 5236-5245 Author Site , DOI
Flaiz C, Utermark T, Parkinson DB, Poetsch A & Hanemann CO (2008) 'Impaired intercellular adhesion and immature adherens junctions in merlin-deficient human primary schwannoma cells' Glia 56, (5) 506-515 Author Site , DOI
Hanemann CO (2008) 'Magic but treatable? Tumours due to loss of Merlin' BRAIN 131, 606-615 Author Site , DOI
Hanemann CO (2008) 'Function of Merlin in Genesis of Tumours and Other Symptoms of NF2' 167-176 , DOI
Hanemann CO, Hayward C & Hilton DA (2007) 'Neurofibromatosis type 1 with involvement of the enteric nerves' J Neurol Neurosurg Psychiatry 78, (10) 1163-1164 Author Site , DOI
Flaiz C, Kaempchen K, Matthies C & Hanemann CO (2007) 'Actin-rich protrusions and nonlocalized GTPase activation in Merlin-deficient schwannornas' JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 66, (7) 608-616 Author Site , DOI
Gdynia HJ, Sperfeld A-D & Hanemann CO (2007) 'Central core myopathy. A juvenile and adult disease' NERVENARZT 78, (4) 387-+ Author Site , DOI
Hanemann O, Diebold R & Kaufmann D (2007) 'Role of NF2 Haploinsufficiency in NF2-associated Polyneuropathy' Brain Pathology 0, (0) 371-376 , DOI
Gdynia HJ, Sperfeld AD, Knirsch U, Homberg V, Rosenbohm A, Müller-Höcker J & Hanemann CO (2007) 'Axonale Neuropathie und Auffälligkeiten der mitochondrialen tRNA bei einem Patienten mit benigner symmetrischer Lipomatose' Klinische Neurophysiologie 38, (01) , DOI
Flaiz C & Hanemann CO (2007) 'Actin-rich protrusions and non-localised GTPase activation in merlin-deficient schwannomas' NEURON GLIA BIOLOGY 2, S123-S123 Author Site
Flaiz C, Kaempchen K, Matthies C & Hanemann CO (2007) 'Actin-rich protrusions and nonlocalized GTPase activation in Merlin-deficient schwannornas' Journal of Neuropathology and Experimental Neurology 66, (7) 608-616
Gdynia HJ, Sperfeld AD & Hanemann CO (2007) 'Central core myopathy. A juvenile and adult disease' Nervenarzt 78, (4) 387-+
Flaiz C & Hanemann OC (2007) 'Like to move it? Actin-rich protrusions, migration and adhesion in schwannoma, a benign tumour of the nervous system' Neuropathology and Applied Neurobiology 33, (2) 259-259
Hanemann CO, Hayward C & Hilton DA (2007) 'Neurofibromatosis type 1 with involvement of the enteric nerves' Journal of Neurology Neurosurgery and Psychiatry 78, (10) 1163-1164
Hanemann CO (2007) 'Pathobiology of schwannomas' Journal of Neurology Neurosurgery and Psychiatry 78, (2)
Ammoun S & Hanemann O (2007) 'Strong and long-lasting activation of ERK in human schwannoma cells' Neuropathology and Applied Neurobiology 33, (2) 258-259
Flaiz C & Hanemann CO (2007) 'Actin-rich protrusions and non-localised GTPase activation in merlin-deficient schwannomas' Neuron Glia Biology 2, S123-S123
Hanemann CO, Diebold R & Kaufmann D (2007) 'Role of NF2 haploinsufficiency in NF2-associated polyneuropathy' Brain Pathology 17, (4) 371-376
Titley G (2007) 'Electronic signatures for copyright in the UK: a solution to the "holy grail" of document delivery' Interlending and Document Supply 35, (1) 15-20 , DOI Open access
Gdynia H-J, Sperfeld A-D, Knirsch U, Homberg V, Rosenbohm A, Müller-Höcker J, Ludolph AC & Hanemann CO (2006) 'Benign symmetric lipomatosis with axonal neuropathy and abnormalities in specific mitochondrial tRNA regions' Eur J Med Res 11, (12) 545-546 Author Site
Hanemann CO, Bartelt-Kirbach B, Diebold R, Kaempchen K, Langmesser S & Utermark T (2006) 'Differential gene expression between human schwannoma and control Schwann cells' NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY 32, (6) 605-614 Author Site , DOI
Hanemann CO & Evans DG (2006) 'News on the genetics, epidemiology, medical care and translational research of Schwannomas' JOURNAL OF NEUROLOGY 253, (12) 1533-1541 Author Site , DOI
Gronholm M, Muranen T, Toby GG, Utermark T, Hanemann CO, Golemis EA & Carpen O (2006) 'A functional association between merlin and HEI10, a cell cycle regulator' ONCOGENE 25, (32) 4389-4398 Author Site , DOI
Hanemann CO (2006) 'Demyelinating Neuropathies: Hereditary' , DOI
Hanemann CO (2006) 'Insights from the development of Schwann cell tumours' Neuromuscular Disorders 16, S105-S106
Hanemann CO & Evans DG (2006) 'News on the genetics, epidemiology, medical care and translational research of Schwannomas' Journal of Neurology 253, (12) 1533-1541
Titley G (2006) 'Practical Issues: Copyright for Clinical Teachers' The Clinical Teacher 3, (1) 60-64 Publisher Site
Hanemann CO & Ludolph AC (2005) 'Motor protein diseases of the nervous system' AMYOTROPHIC LATERAL SCLEROSIS AND OTHER MOTOR NEURON DISORDERS 6, (4) 197-201 Author Site , DOI
Munch C, Rosenbohm A, Sperfeld AD, Uttner I, Reske S, Krause BJ, Sedlmeier R, Meyer T, Hanemann CO & Stumm G (2005) 'Heterozygous R1101K mutation of the DCTN1 gene in a family with ALS and FTD' ANNALS OF NEUROLOGY 58, (5) 777-780 Author Site , DOI
Biebl A, Kaempchen KE, Utermark T, Maruta H & Hanemann CO (2005) 'Die Rolle von PAK in der Pathophysiologie humaner Schwannome: ein zukünftiges therapeutisches Target?' Aktuelle Neurologie 32, (S 4) , DOI
Gdynia HJ, Kassubek J, Hanemann CO, Ludolph AC & Sperfeld AD (2005) 'Laryngospasmus bei x-chromosomaler Spinobulbärer Muskelatrophie (Kennedy-Syndrom)' Aktuelle Neurologie 32, (S 4) , DOI
Muench C, Rosenbohm A, Sperfeld AD, Uttner I, Meyer T, Hanemann CO, Stumm G & Ludolph AC (2005) 'Heterozygous R1101K mutation of the DCTN1 gene in a family with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD)' EUROPEAN JOURNAL OF NEUROLOGY 12, 27-27 Author Site
Hanemann CO, Kaempchen KE, Kaufmann D & Krause BJ (2005) 'Fludeoxyglucose F 18 positron emission tomography and computed tomography of a giant retroperitoneal schwannoma occurring in a patient with neurofibromatosis type 2' ARCHIVES OF NEUROLOGY 62, (4) 674-675 Author Site , DOI
Hirokowa Y, Nakajima H, Hanemann CO, Kurtz A, Frahm S, Mautner V & Maruta H (2005) 'Signal therapy of NF1-deficient tumor xenograft in mice by the anti-PAK1 drug FK228' CANCER BIOLOGY & THERAPY 4, (4) 379-381 Author Site
Sperfeld AD, Hanemann CO, Ludolph AC & Kassubek J (2005) 'Laryngospasm: An underdiagnosed symptom of X-linked spinobulbar muscular atrophy' NEUROLOGY 64, (4) 753-754 Author Site , DOI
Diebold R, Bartelt-Kirbach B, Evans DG, Kaufmann D & Hanemann CO (2005) 'Sensitive detection of deletions of one or more exons in the neurofibromatosis type 2 (NF2) gene by multiplexed gene dosage polymerase chain reaction' JOURNAL OF MOLECULAR DIAGNOSTICS 7, (1) 97-104 Author Site , DOI
Hanemann CO, Kaempchen KE, Kaufmann D & Krause BJ (2005) 'Fludeoxyglucose F 18 positron emission tomography and computed tomography of a giant retroperitoneal schwannoma occurring in a patient with neurofibromatosis type 2' Archives of Neurology 62, (4) 674-675
Munch C, Rosenbohm A, Sperfeld AD, Uttner I, Reske S, Krause BJ, Sedlmeier R, Meyer T, Hanemann CO & Stumm G (2005) 'Heterozygous R1101K mutation of the DCTN1 gene in a family with ALS and FTD' Annals of Neurology 58, (5) 777-780
Muench C, Rosenbohm A, Sperfeld AD, Uttner I, Meyer T, Hanemann CO, Stumm G & Ludolph AC (2005) 'Heterozygous R1101K mutation of the DCTN1 gene in a family with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD)' European Journal of Neurology 12, 27-27
Sperfeld AD, Hanemann CO, Ludolph AC & Kassubek J (2005) 'Laryngospasm: An underdiagnosed symptom of X-linked spinobulbar muscular atrophy' Neurology 64, (4) 753-754
Hanemann CO & Ludolph AC (2005) 'Motor protein diseases of the nervous system' Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders 6, (4) 197-201
Sperfeld AD, Bretschneider V, Flaith L, Unrath A, Hanemann CO, Ludolph AC & Kassubek J (2005) 'MR-Pathologic comparison of the upper spinal cord in different motor neuron diseases' EUROPEAN NEUROLOGY 53, (2) 74-77 Author Site , DOI
Sperfeld AD, Bretschneider V, Flaith L, Unrath A, Hanemann CO, Ludolph AC & Kassubek J (2005) 'MR-Pathologic comparison of the upper spinal cord in different motor neuron diseases' European Neurology 53, (2) 74-77
Utermark T, Schubert SJA & Hanemann CO (2005) 'Rearrangements of the intermediate filament GFAP in primary human schwannoma cells' NEUROBIOLOGY OF DISEASE 19, (1-2) 1-9 Author Site , DOI
Utermark T, Schubert SJA & Hanemann CO (2005) 'Rearrangements of the intermediate filament GFAP in primary human schwannoma cells' Neurobiology of Disease 19, (1-2) 1-9
Utermark T, Kaempchen K, Antoniadis G & Hanemann CO (2005) 'Reduced apoptosis rates in human schwannomas' BRAIN PATHOLOGY 15, (1) 17-22 Author Site
Utermark T, Kaempchen K, Antoniadis G & Hanemann CO (2005) 'Reduced apoptosis rates in human schwannomas' Brain Pathology 15, (1) 17-22
Diebold R, Bartelt-Kirbach B, Evans DG, Kaufmann D & Hanemann CO (2005) 'Sensitive detection of deletions of one or more exons in the neurofibromatosis type 2 (NF2) gene by multiplexed gene dosage polymerase chain reaction' Journal of Molecular Diagnostics 7, (1) 97-104
Hirokowa Y, Nakajima H, Hanemann CO, Kurtz A, Frahm S, Mautner V & Maruta H (2005) 'Signal therapy of NF1-deficient tumor xenograft in mice by the anti-PAK1 drug FK228' Cancer Biology & Therapy 4, (4) 379-381
Munch C, Rosenbohm A, Sperfeld AD, Uttner I, Reske S, Meyer T, Hanemann CO, Stumm G & Ludolph AC (2005) 'Heterozygous R1101K mutation of the DCTN1 gene in a family with amyotrophic lateral sclerosis and frontotemporal dementia' Journal of Neurology 252, 18-18
Sperfeld AD, Kassubek J, Crosby AH, Winner B, Ludolph AC, Uttner I & Hanemann CO (2004) 'Complicated hereditary spastic paraplegia with thin corpus callosum: Variation of phenotypic expression over time' JOURNAL OF NEUROLOGY 251, (10) 1285-1287 Author Site , DOI
Munch C, Sedlmeier R, Meyer T, Homberg V, Sperfeld AD, Kurt A, Prudlo J, Peraus G, Hanemann CO & Stumm G (2004) 'Point mutations of the p150 subunit of dynactin (DCTN1) gene in ALS' NEUROLOGY 63, (4) 724-726 Author Site , DOI
Walter MC, Petersen JA, Stucka R, Fischer D, Schroder R, Vorgerd M, Schroers A, Schreiber H, Hanemann CO & Knirsch U (2004) 'FKRP (826C > A) frequently causes limb-girdle muscular dystrophy in German patients' JOURNAL OF MEDICAL GENETICS 41, (4) Author Site , DOI
Paparounas K (2004) 'Kennedy Disease: Insights and Questions' Archives of Neurology 61, (4) 603-603 , DOI
Paparounas K (2004) 'Kennedy disease: insights and questions' Arch Neurol 61, (4) Author Site , DOI
Sperfeld A-D & Hanemann CO (2004) 'Kennedy Disease: Insights and Questions—Reply' Archives of Neurology 61, (4) 603-603 , DOI
Hirokawa Y, Tikoo A, Huynh J, Utermark T, Hanemann CO, Giovannini M, Xiao GH, Testa JR, Wood J & Maruta H (2004) 'A clue to the therapy of neurofibromatosis type 2: NF2/Merlin is a PAK1 inhibitor' CANCER JOURNAL 10, (1) 20-26 Author Site , DOI
Hirokawa Y, Tikoo A, Huynh J, Utermark T, Hanemann CO, Giovannini M, Xiao GH, Testa JR, Wood J & Maruta H (2004) 'A clue to the therapy of neurofibromatosis type 2: NF2/Merlin is a PAK1 inhibitor' Cancer Journal 10, (1) 20-26
Walter MC, Petersen JA, Stucka R, Fischer D, Schroder R, Vorgerd M, Schroers A, Schreiber H, Hanemann CO & Knirsch U (2004) 'FKRP (826C > A) frequently causes limb-girdle muscular dystrophy in German patients' Journal of Medical Genetics 41, (4)
Munch C, Sedlmeier R, Meyer T, Homberg V, Sperfeld AD, Kurt A, Prudlo J, Peraus G, Hanemann CO & Stumm G (2004) 'Point mutations of the p150 subunit of dynactin (DCTN1) gene in ALS' Neurology 63, (4) 724-726
Muench C, Sedlmeier R, Meyer T, Homberg V, Sperfeld AD, Kurt A, Prudlo J, Peraus G, Hanemann CO & Stumm G (2004) 'Point mutations of the p150 subunit of dynactin (DCTN1) gene in amyotrophic lateral sclerosis' Annals of Neurology 56, S30-S30
Sperfeld AD, Kassubek J, Crosby AH, Winner B, Ludolph AC, Uttner I & Hanemann CO (2004) 'Complicated hereditary spastic paraplegia with thin corpus callosum: Variation of phenotypic expression over time' Journal of Neurology 251, (10) 1285-1287
Walter MC, Petersen JA, Stucka R, Fischer D, Schroder R, Vorgerd M, Schroers A, Schreiber H, Hanemann CO & Knirsch U (2004) 'FKRP (826C > A) frequently causes limb-girdle muscular dystrophy in German patients' Journal of Neurology 251, 15-15
Munch C, Sperfeld AD, Meyer T, Prudlo J, Hanemann CO, Stumm G & Ludolph AC (2004) 'Point mutations of the p150 subunit of dynactin (DCTN1) and absence of mutations in the cytoplasmic dynein heavy chain (DNCHC1) gene in amyotrophic lateral sclerosis' Journal of Neurology 251, 33-33
Sedlmeier R, Meyer T, Sperfeld AD, Kurt A, Homberg V, Prudlo J, Peraus G, Hanemann CO, Stumm G & Ludolph AC (2004) 'Heterozygote Punktmutationen in der p150 Untereinheit des Dynactin-Gens bei der amyotrophen Lateralsklerose' Aktuelle Neurologie 31, (S 1) , DOI
Sperfeld AD, Hanemann CO, Uttner I, Unrath A & Kassubek J (2004) 'Klinische und kernspintomographische Verlaufsuntersuchung bei Patienten mit einer komplizierten hereditären spastischen Paraparese und dünnem Corpus callosum' Aktuelle Neurologie 31, (S 1) , DOI
Kämpchen K, Utermark T, Diebold R & Hanemann CO (2004) 'Neurofibromatose Typ 2: Charakterisierung einer hereditären Tumorerkrankung' Aktuelle Neurologie 31, (S 1) , DOI
Zuchner S, Sperfeld AD, Senderek J, Sellhaus B, Hanemann CO & Schroder JM (2003) 'A novel nonsense mutation in the ABC1 gene causes a severe syringomyelia-like phenotype of Tangier disease (vol 126, pg 920, 2003)' BRAIN 126, 2115-2115 Author Site
(2003) 'Erratum' Brain 126, (9) 2115-2115 , DOI
Utermark T, Kaempchen K & Hanemann CO (2003) 'Pathological adhesion of primary human schwannoma cells is dependent on altered expression of integrins' BRAIN PATHOLOGY 13, (3) 352-363 Author Site
Hanemann CO & Ludolph AC (2003) 'ALS/MND meeting of the European AlS/MND group Reisensburg Castle 30 January - 1 February 2003' Amyotroph Lateral Scler Other Motor Neuron Disord 4, (2) 121-122 Author Site , DOI
Hanemann CO & Ludolph AC (2003) 'ALS/MND meeting of the European ALS/MND group Reisensburg Castle 30 January - 1 February 2003' Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders 4, (2) 121-122 , DOI
Utermark T, Alekov A, Lerche H, Abramowski V, Giovannini M & Hanemann CO (2003) 'Quinidine impairs proliferation of neurofibromatosis type 2-deficient human malignant mesothelioma cells' CANCER 97, (8) 1955-1962 Author Site , DOI
Zuchner S, Sperfeld AD, Senderek J, Sellhaus B, Hanemann CO & Schroder JM (2003) 'A novel nonsense mutation in the ABC1 gene causes a severe syringomyelia-like phenotype of Tangier disease' BRAIN 126, 920-927 Author Site , DOI
Hanemann CO, Bergmann C, Senderek J, Zerres K & Sperfeld AD (2003) 'Transient, recurrent, white matter lesions in x-linked Charcot-Marie-Tooth disease with novel connexin 32 mutation' ARCHIVES OF NEUROLOGY 60, (4) 605-609 Author Site , DOI
Hanemann O, Kaempchen K, Mielke K & Utermark T (2003) 'Upregulation of the Rac1/JNK signaling pathway in primary human schwannoma cells' Human Molecular Genetics 12, (11) 1211-1221 , DOI
Zuchner S, Sperfeld AD, Senderek J, Sellhaus B, Hanemann CO & Schroder JM (2003) 'A novel nonsense mutation in the ABC1 gene causes a severe syringomyelia-like phenotype of Tangier disease' Brain 126, 920-927
Utermark T, Kaempchen K & Hanemann CO (2003) 'Pathological adhesion of primary human schwannoma cells is dependent on altered expression of integrins' Brain Pathology 13, (3) 352-363
Utermark T, Alekov A, Lerche H, Abramowski V, Giovannini M & Hanemann CO (2003) 'Quinidine impairs proliferation of neurofibromatosis type 2-deficient human malignant mesothelioma cells' Cancer 97, (8) 1955-1962
Chtarto A, Bender HU, Hanemann CO, Kemp T, Lehtonen E, Levivier M, Brotchi J, Velu T & Tenenbaum L (2003) 'Tetracycline-inducible transgene expression mediated by a single AAV vector' Gene Therapy 10, (1) 84-94
Chtarto A, Bender HU, Hanemann CO, Kemp T, Lehtonen E, Levivier M, Brotchi J, Velu T & Tenenbaum L (2003) 'Tetracycline-inducible transgene expression mediated by a single AAV vector' GENE THERAPY 10, (1) 84-94 Author Site , DOI
Hanemann CO, Bergmann C, Senderek J, Zerres K & Sperfeld AD (2003) 'Transient, recurrent, white matter lesions in x-linked Charcot-Marie-Tooth disease with novel connexin 32 mutation' Archives of Neurology 60, (4) 605-609
Kaempchen K, Mielke K, Utermark T, Langmesser S & Hanemann CO (2003) 'Upregulation of the Rac1/JNK signaling pathway in primary human schwannoma cells' Human Molecular Genetics 12, (11) 1211-1221
Sperfeld AD, Karitzky J, Brummer D, Schreiber H, Haussler J, Ludolph AC & Hanemann CO (2002) 'X-linked bulbospinal neuronopathy - Kennedy disease' ARCHIVES OF NEUROLOGY 59, (12) 1921-1926 Author Site , DOI
Hanemann CO & Ludolph AC (2002) 'Hereditary motor neuropathies and motor neuron diseases: which is which' Amyotroph Lateral Scler Other Motor Neuron Disord 3, (4) 186-189 Author Site , DOI
Hanemann CO & Gabreels-Festen AAWM (2002) 'Secondary axon atrophy and neurological dysfunction in demyelinating neuropathies' CURRENT OPINION IN NEUROLOGY 15, (5) 611-615 Author Site , DOI
Hanemann CO, Gabreels-Festen AAWM & De Jonghe P (2002) 'Axon damage in CMT due to mutation in myelin protein P0 (vol 11, pg 753, 2001)' NEUROMUSCULAR DISORDERS 12, (4) 432-432 Author Site , DOI
Utermark T, McLaughlin K & Hanemann CO (2002) 'Enhanced adhesion of Schwannoma cells is dependent on an increased expression of the integrin alpha 6, beta 1 and beta 4 chains in vitro' GLIA S31-S31 Author Site
Hanemann O, Hein C, Schroder M & Sperfeld A (2002) 'Occurrence and characterization of  peripheral nerve involvement in neurofibromatosis type 2' Brain 125, (5) 996-1004 , DOI
Hanemann O, Hanenberg H, Muller H & Schulze K (2002) 'Transduction of wild-type merlin into human schwannoma cells decreases schwannoma cell growth and induces apoptosis' Human Molecular Genetics 11, (1) 69-76 , DOI
Hanemann CO, Gabreels-Festen AAWM & De Jonghe P (2002) 'Axon damage in CMT due to mutation in myelin protein P0 (vol 11, pg 753, 2001)' Neuromuscular Disorders 12, (4) 432-432
Zuchner S, Sperfeld A, Hanemann CO & Schroder JM (2002) 'Novel point mutation of the ABC1 gene in Tangier disease with severe syringomyelia-like phenotype and unique endoneurial sclerosis' Journal of the Neurological Sciences 199,
Hanemann CO, Sperfeld AD, Hein C, Schroder JM & Ludolph AC (2002) 'Occurrence and characterisation of peripheral nerve involvement in neurofibromatosis type 2' Journal of the Neurological Sciences 199,
Sperfeld AD, Hein C, Schroder JM, Ludolph AC & Hanemann CO (2002) 'Occurrence and characterization of peripheral nerve involvement in neurofibromatosis type 2' Brain 125, 996-1004
Hanemann CO & Gabreels-Festen AAWM (2002) 'Secondary axon atrophy and neurological dysfunction in demyelinating neuropathies' Current Opinion in Neurology 15, (5) 611-615
Schulze KMM, Hanemann CO, Muller HW & Hanenberg H (2002) 'Transduction of wild-type merlin into human schwannoma cells decreases schwannoma cell growth and induces apoptosis' Human Molecular Genetics 11, (1) 69-76
Sperfeld AD, Karitzky J, Brummer D, Schreiber H, Haussler J, Ludolph AC & Hanemann CO (2002) 'X-linked bulbospinal neuronopathy - Kennedy disease' Archives of Neurology 59, (12) 1921-1926
Hanemann CO, Sperfeld AD, Karitzky J, Schreiber H, Brummer D, Haussler J & Ludolph AC (2002) 'X-linked bulbospinal neuronopathy Kennedy: Presence of known and unknown clinical features and electrophysiological investigation in 34 cases' Journal of the Neurological Sciences 199,
Utermark T, McLaughlin K & Hanemann CO (2002) 'Enhanced adhesion of Schwannoma cells is dependent on an increased expression of the integrin alpha 6, beta 1 and beta 4 chains in vitro' Glia S31-S31
Kaufmann D, Muller R, Bartelt B, Wolf M, Kunzi-Rapp K, Hanemann CO, Fahsold R, Hein C, Vogel W & Assum G (2001) 'Spinal neurofibromatosis without cafe-au-lait macules in two families with null mutations of the NF1 gene' AMERICAN JOURNAL OF HUMAN GENETICS 69, (6) 1395-1400 Author Site , DOI
Hanemann CO, Gabreels-Festen AAWM & De Jonghe P (2001) 'Axon damage in CMT due to mutation in myelin protein P0' NEUROMUSCULAR DISORDERS 11, (8) 753-756 Author Site , DOI
Hanemann CO (2001) 'Hereditary demyelinating neuropathies: from gene to disease' NEUROGENETICS 3, (2) 53-57 Author Site , DOI
Rosenbaum C, Kamleiter M, Grafe P, Kluwe L, Mautner V-F, Müller HW & Hanemann CO (2001) 'Enhanced Proliferation and Potassium Conductance of Schwann Cells Isolated from NF2 Schwannomas Can Be Reduced by Quinidine' Neurobiology of Disease 8, (1) 181-181 , DOI
Hanemann CO, Gabreels-Festen AAWM & De Jonghe P (2001) 'Axon damage in CMT due to mutation in myelin protein P0' Neuromuscular Disorders 11, (8) 753-756
Hanemann CO (2001) 'Hereditary demyelinating neuropathies: from gene to disease' Neurogenetics 3, (2) 53-57
Kaufmann D, Muller R, Bartelt B, Wolf M, Kunzi-Rapp K, Hanemann CO, Fahsold R, Hein C, Vogel W & Assum G (2001) 'Spinal neurofibromatosis without cafe-au-lait macules in two families with null mutations of the NF1 gene' American Journal of Human Genetics 69, (6) 1395-1400
Rosenbaum C, Kamleiter M, Grafe P, Kluwe L, Mautner V-F, Müller HW & Hanemann CO (2000) 'Enhanced Proliferation and Potassium Conductance of Schwann Cells Isolated from NF2 Schwannomas Can Be Reduced by Quinidine' Neurobiology of Disease 7, (6) 691-691 , DOI
Hanemann C, D'urso D, Gabreels-Festen A & Muller H (2000) 'MUTATION-DEPENDENT ALTERATION IN CELLULAR DISTRIBUTION OF PERIPHERAL MYELIN PROTEIN 22 IN NERVE BIOPSIES FROM CHARCOT-MARIE-TOOTH TYPE 1A' Journal of the Peripheral Nervous System 5, (4) 251-251 , DOI
Hanemann C, D'urso D, Gabreels-Festen A & Muller H (2000) 'MUTATION‐DEPENDENT ALTERATION IN CELLULAR DISTRIBUTION OF PERIPHERAL MYELIN PROTEIN 22 IN NERVE BIOPSIES FROM CHARCOT‐MARIE‐TOOTH TYPE 1A' Journal of the Peripheral Nervous System 5, (4) 251-251 , DOI
Rosenbaum T, Rosenbaum C, Winner U, Muller HW, Lenard HG & Hanemann CO (2000) 'Long-term culture and characterization of human neurofibroma-derived Schwann cells' JOURNAL OF NEUROSCIENCE RESEARCH 61, (5) 524-532 Author Site , DOI
Rosenbaum C, Kamleiter M, Grafe P, Kluwe L, Mautner VF, Muller HW & Hanemann CO (2000) 'Enhanced proliferation and potassium conductance of schwann cells isolated from NF2 schwannomas can be reduced by quinidine' NEUROBIOLOGY OF DISEASE 7, (4) 483-491 Author Site , DOI
Jamar M, Hanemann C, Gaillez S & Herens C (2000) 'Autosomal aneuploidy rate in spermatozoa: a comparison between normospermic and oligospermic males, using a double-color FISH' Immuno-analyse &amp; Biologie Spécialisée 15, (4) 262-266 , DOI
Hanemann CO, D'Urso D, Gabreels-Festen AAWM & Muller HW (2000) 'Mutation-dependent alteration in cellular distribution of peripheral myelin protein 22 in nerve biopsies from Charcot-Marie-Tooth type 1A' BRAIN 123, 1001-1006 Author Site , DOI
Rosenbaum T, Rosenbaum C, Winner U, M?ller HW, Lenard H-G & Hanemann CO (2000) 'Long-term culture and characterization of human neurofibroma-derived Schwann cells' Journal of Neuroscience Research 61, (5) 524-532 , DOI
Hanemann CO & Neuen-Jacob E (1999) 'Muscle injury in Guillain-Barre syndrome: a case report' JOURNAL OF NEUROLOGY 246, (12) 1207-1208 Author Site , DOI
Tenenbaum L, Hamdane M, Pouzet M, Avalosse B, Stathopoulos A, Jurysta F, Rosenbaum C, Hanemann CO, Levivier M & Velu T (1999) 'Cellular contaminants of adeno-associated virus vector stocks can enhance transduction' GENE THERAPY 6, (6) 1045-1053 Author Site , DOI
Mayer C, Kamleiter M, Sanchez-Brandelik R, Rosenbaum C, Kluwe L, Hanemann CO & Grafe P (1999) 'Neuroligand-mediated calcium signaling in cultured human schwannoma cells' JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM 4, (2) 99-105 Author Site
Kappos L, European Study Group on Interferon ß-1b in Secondary Progressive MS & Hanemann CO (1998) 'Placebo-controlled multicentre randomised trial of interferon ß-1b in treatment of secondary progressive multiple sclerosis' The Lancet 352, (9139) 1491-1497 , DOI
Stoll G, Gabreels-Festen AAWM, Jander S, Muller HW & Hanemann CO (1998) 'Major histocompatibility complex class II expression and macrophage responses in genetically proven Charcot-Marie-Tooth type 1 and hereditary neuropathy with liability to pressure palsies' MUSCLE & NERVE 21, (11) 1419-1427 Author Site , DOI
Kamleiter M, Hanemann CO, Kluwe L, Rosenbaum C, Wosch S, Mautner VF, Muller HW & Grafe P (1998) 'Voltage-dependent membrane currents of cultured human neurofibromatosis type 2 Schwann cells' GLIA 24, (3) 313-322 Author Site , DOI
Kamleiter M, Hanemann CO, Kluwe L, Rosenbaum C, Wosch S, Mautner VF, Werner M?ller H & Grafe P (1998) 'Voltage-dependent membrane currents of cultured human neurofibromatosis type 2 Schwann cells' Glia 24, (3) 313-322 , DOI
Stoll G, Gabreels-Festen AAWM, Jander S, Muller HW & Hanemann CO (1998) 'Major histocompatibility complex class II expression and macrophage responses in genetically proven Charcot-Marie-Tooth type 1 and hereditary neuropathy with liability to pressure palsies' Muscle and Nerve 21, (11) 1419-1427 , DOI
Rosenbaum C, Kluwe L, Mautner VF, Friedrich RE, Muller HW & Hanemann CO (1998) 'Isolation and characterization of Schwann cells from neurofibromatosis type 2 patients' NEUROBIOLOGY OF DISEASE 5, (1) 55-64 Author Site , DOI
Hanemann CO & Muller HW (1998) 'Pathogenesis of Charcot-Marie-Tooth IA (CMTIA) neuropathy' TRENDS IN NEUROSCIENCES 21, (7) 282-286 Author Site , DOI
Hanemann CO, Rosenbaum C, Kupfer S, Wosch S, Stoegbauer F & Muller HW (1998) 'Improved culture methods to expand schwann cells with altered growth behaviour from CMT1A patients' GLIA 23, (2) 89-98 Author Site , DOI
Hanemann CO, Rosenbaum C, Kupfer S, Wosch S, Stoegbauer F & Müller HW (1998) 'Improved culture methods to expand schwann cells with altered growth behaviour from CMT1a patients' GLIA 23, (2) 89-98 , DOI
Hermanns S, Wunderlich G, Rosenbaum C, Hanemann CO, Muller HW & Stichel CC (1997) 'Lack of immune responses to immediate or delayed implanted allogeneic and xenogeneic Schwann cell suspensions' GLIA 21, (3) 299-314 Author Site
Hermanns S, Wunderlich G, Rosenbaum C, Hanemann CO, M?ller HW & Stichel CC (1997) 'Lack of immune responses to immediate or delayed implanted allogeneic and xenogeneic Schwann cell suspensions' Glia 21, (3) 299-314 , DOI
Hermanns S, Wunderlich G, Rosenbaum C, Hanemann CO, Müller HW & Stichel CC (1997) 'Lack of immune responses to immediate or delayed implanted allogeneic and xenogeneic Schwann cell suspensions' Glia 21, (3) 299-314 , DOI
Hanemann CO, GabreelsFesten AAWM, Stoll G & Muller HW (1997) 'Schwann cell differentiation in Charcot-Marie-Tooth disease type 1A (CMT1A): normal number of myelinating Schwann cells in young CMT1A patients and neural cell adhesion molecule expression in onion bulbs' ACTA NEUROPATHOLOGICA 94, (4) 310-315 Author Site , DOI
Korinthenberg R, Sauer M, Ketelsen UP, Hanemann CO, Stoll G, Graf M, Baborie A, Volk B, Wirth B & RudnikSchoneborn S (1997) 'Congenital axonal neuropathy caused by deletions in the spinal muscular atrophy region' ANNALS OF NEUROLOGY 42, (3) 364-368 Author Site , DOI
Muller HW, DUrso D, Zoidl G & Hanemann CO (1997) 'Peripheral myelin protein 22kD (PMP22): Structure, function and role in demyelinating hereditary neuropathies' JOURNAL OF NEUROCHEMISTRY 69, S94-S94 Author Site
Müller HW, Suter U, Van Broeckhoven C, Hanemann CO, Nelis E, Timmerman V, Sancho S, Barrio L, Bolhuis P & Dermietzel R (1997) 'Advances in Charcot-Marie-Tooth disease research: cellular function of CMT-related proteins, transgenic animal models, and pathomechanisms. The European CMT Consortium' Neurobiol Dis 4, (3-4) 215-220 Author Site , DOI
Hanemann CO, GabreelsFesten AAWM, Muller HW & Stoll G (1996) 'Low affinity NGF receptor expression in CMT1A nerve biopsies of different disease stages' BRAIN 119, 1461-1469 Author Site , DOI
Hanemann CO, Hefter H, Schlaug G, Seitz RJ, Freund HJ & Benecke R (1996) 'Characterization of basal ganglia dysfunction in Leber 'plus' disease' JOURNAL OF NEUROLOGY 243, (3) 297-300 Author Site , DOI
Nelis E & Van Broeckhoven C (1996) 'Estimation of the Mutation Frequencies in Charcot-Marie-Tooth Disease Type 1 and Hereditary Neuropathy with Liability to Pressure Palsies: A European Collaborative Study' European Journal of Human Genetics 4, (1) 25-33 , DOI
HANEMANN CO, STOLL G & MULLER HW (1995) 'PMP22 EXPRESSION IN CMT1A NEUROPATHY' ANNALS OF NEUROLOGY 37, (1) 136-136 Author Site , DOI
HANEMANN CO, STOLL G, DURSO D, FRICKE W, MARTIN JJ, VAN BROECKHOVEN C, MANCARDI GL, BARTKE I & MULLER HW (1994) 'PERIPHERAL MYELIN PROTEIN-22 EXPRESSION IN CHARCOT-MARIE-TOOTH DISEASE TYPE 1A SURAL NERVE BIOPSIES' JOURNAL OF NEUROSCIENCE RESEARCH 37, (5) 654-659 Author Site , DOI
HANEMANN CO, KLEINSCHMIDT A, REIFENBERGER G, FREUND HJ & SEITZ RJ (1993) 'BALO CONCENTRIC SCLEROSIS FOLLOWED BY MRI AND POSITRON EMISSION TOMOGRAPHY' NEURORADIOLOGY 35, (8) 578-580 Author Site , DOI
HANEMANN CO, KUHN G, LIE A, GILLEN C, BOSSE F, SPREYER P & MULLER HW (1993) 'EXPRESSION OF DECORIN MESSENGER-RNA IN THE NERVOUS-SYSTEM OF RAT' JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 41, (9) 1383-1391 Author Site , DOI
Hanemann CO, Kleinschmidt A, Reifenberger G, Freund HJ & Seitz RJ (1993) 'Balo's concentric sclerosis followed by MRI and positron emission tomography' Neuroradiology 35, (8) 578-580 Author Site , DOI
HANEMANN CO, MULLER HW & FREUND HJ (1992) 'MOLECULAR UNDERSTANDING AND DNA TEST FOR CHARCOT-MARIE-TOOTH DISEASE IN SIGHT' AKTUELLE NEUROLOGIE 19, (6) 182-184 Author Site , DOI
MATSUNAMI N, SMITH B, BALLARD L, LENSCH MW, ROBERTSON M, ALBERTSEN H, HANEMANN CO, MULLER HW, BIRD TD & WHITE R (1992) 'PERIPHERAL MYELIN PROTEIN-22 GENE MAPS IN THE DUPLICATION IN CHROMOSOME-17P11.2 ASSOCIATED WITH CHARCOT-MARIE-TOOTH-1A' NATURE GENETICS 1, (3) 176-179 Author Site , DOI
TIMMERMAN V, NELIS E, VANHUL W, NIEUWENHUIJSEN BW, CHEN KL, WANG S, OTHMAN KB, CULLEN B, LEACH RJ & HANEMANN CO (1992) 'THE PERIPHERAL MYELIN PROTEIN GENE PMP-22 IS CONTAINED WITHIN THE CHARCOT-MARIE-TOOTH DISEASE TYPE-1A DUPLICATION' NATURE GENETICS 1, (3) 171-175 Author Site , DOI
SPREYER P, KUHN G, HANEMANN CO, GILLEN C, SCHAAL H, KUHN R, LEMKE G & MULLER HW (1991) 'AXON-REGULATED EXPRESSION OF A SCHWANN-CELL TRANSCRIPT THAT IS HOMOLOGOUS TO A GROWTH ARREST-SPECIFIC GENE' EMBO JOURNAL 10, (12) 3661-3668 Author Site , DOI
Bullock R, Hanemann CO, Murray L & Teasdale GM (1990) 'Recurrent hematomas following craniotomy for traumatic intracranial mass' J Neurosurg 72, (1) 9-14 Author Site , DOI
Ammoun S, Cunliffe CH, Allen JC, Chiriboga L, Giancotti FG, Zagzag D, Hanemann CO & Karajannis MA 'ErbB/HER receptor activation and preclinical efficacy of lapatinib in vestibular schwannoma' Neuro-oncology Publisher Site , DOI Open access
Letters
Sher I, Hanemann CO, Karplus PA & Bretscher A (2012) 'The tumor suppressor merlin controls growth in its open state, and phosphorylation converts it to a less-active more-closed state' Dev Cell 22, (4) 703-705 Author Site , DOI
Chapters
Oliver Hanemann C & Ammoun S (2010) 'Receptor Tyrosine Kinases in Human Schwannoma' Angiogenesis &amp;amp Therapeutic Targets In Cancer BENTHAM SCIENCE PUBLISHERS 90-98 , DOI
Froehlich SJ, Lackerbauer CA, Rudolph G, Rémi J, Noachtar S, Heppt WJ, Cryer A, Zenner H-P, Niller HH & Schwarzmann F (2009) 'Neuropathies, Inherited Peripheral' Encyclopedia of Molecular Mechanisms of Disease Springer Berlin Heidelberg 1461-1467 , DOI
Beniac DR, Ridsdale RA, Luckevich MD, Tompkins TA, Harauz G, Sedzik J, Hjertén S, Brekkan E, Lundahl P & Tropak MB (1997) 'Abstracts' Cell Biology and Pathology of Myelin Springer US 365-386 , DOI
Eckert C & Kutsch O 'Steuerung von Finanznetzwerken' Business Engineering Springer Berlin Heidelberg 129-165 , DOI
Conference Papers
Baiz D, Negroni C, Ferluga S, Ercolano E, Adams C & Hanemann CO (2018) 'High miR-9 levels represent a novel prognostic biomarker to predict development of malignant meningioma' 25th Biennial Congress of the European Association for Cancer Research (EACR25) Amsterdam 6-/-0/20187-/-0/2018Open access
Hanemann CO, Ferluga S, Dunn J, Bassiri K, Sharma V & Lasonder E (2016) 'ANALYSIS OF THE PROTEOM AND PHOSHOPROTEOM OF MENINGIOMAS' 68-68
Dunn J, Ferluga S, Sharma V, Hilton DA, Bassiri K & Hanemann CO (2016) 'Identification of novel molecular targets in stratified meningiomas using a proteomic approach' 20-20
Hilton DA, Shivane A, Kirk L, Bassiri K & Hanemann CO (2015) 'GROWTH FACTOR SIGNALLING PATHWAYS IN MENINGIOMAS IS COMMON AND PARTLY DEPENDS ON SUBTYPE ALLOWING FOR STRATIFICATION' 14-14
Hanemann CO, Zhou L, Ammoun S, Lasonder E, Sharma V, Muller J & Ercolano E (2015) 'Abstract 704: Scaffold protein KSR1 is negatively regulated by merlin and promotes tumor development in merlin deficient tumors' American Association for Cancer Research (AACR) 704-704 , DOI
Sittampalam M & Hanemann O (2014) 'CLINICAL MORVAN'S AND ELECTRICAL MND' , DOI
Hanemann CO, Ammoun S, Schmid MC & Zhou L (2014) 'Abstract 2609: The role of focal adhesion kinase (FAK), PI3K/AKT and p53/mouse double minute 2 homologue (MDM2) complex in the pathobiology of Merlin-deficient tumors' American Association for Cancer Research (AACR) 2609-2609 , DOI
Hanemann CO, Hilton D, Shivane A & Turner L (2014) 'ACTIVATION OF MULTIPLE GROWTH FACTOR SIGNALLING PATHWAYS IS FREQUENT IN MENINGIOMAS'
Hilton D, Shivane A, Kirk L, Ammoun S & Hanemann CO (2014) 'Growth factor signaling pathway activation in meningiomas' 101-101
Schulz A, Baader S, Niwa-Kawakita M, Bauer R, Jung J, Zoch A, Schacke S, Hagel C, Mautner V & Hanemann O (2013) 'THE ROLE OF MERLIN ISOFORM 2 IN NEUROFIBROMATOSIS TYPE 2-ASSOCIATED POLYNEUROPATHY' S104-S104
Barczyk M, Zhou L, Avent N & Hanemann O (2013) 'Tumour suppressor merlin regulates thrombospondin 1 signalling via CD47' 381-381
Hilton DA, Shivane A, Turner L, Ammoun S & Hanemann O (2013) 'Activation of multiple signalling pathways in meningiomas is unrelated to NF2 gene status' 35-35
Salter E, Zeissler ML, Alexander SPH, Hanemann CO, Zajicek JP & Carroll CB (2012) 'ENDOCANNABINOID TOXICITY IN A CELL CULTURE MODEL OF PARKINSON'S DISEASE' BMJ A13.4-A14 , DOI
Zeissler M, Hanemann CO, Zajicek JP & Carroll CB (2012) 'FAAH INHIBITION IS PROTECTIVE IN A CELL CULTURE MODEL OF PARKINSON'S DISEASE' , DOI
Barczyk M, Zhou L, Avent N & Hanemann O (2012) 'Tumour Suppressor Merlin Regulates Thrombospondin 1 Signalling Via CD47' 162-162 , DOI
Shivane A, Ammoun S, Parkinson DB & Hanemann CO (2012) 'EXPRESSION OF C-JUN & SOX-2 IN HUMAN SCHWANNOMAS AND TRAUMATIC NEUROMAS' 9-10
Zhou L, Ercolano E, Ammoun S, Schmid MC, Barczyk M & Hanemann CO (2012) 'MERLIN DEFICIENT HUMAN TUMOURS SHOW LOSS OF CONTACT INHIBITION, ACTIVATION OF WNT/beta-CATENIN SIGNALING LINKED TO THE PDGFR/SRC AND RAC/PAK PATHWAYS' 5-6
Zeissler ML, Hanemann O, Zajicek JP & Carroll CB (2012) 'Delta(9)-THC is protective in a cell culture model of Parkinson's disease through a PPAR gamma mediated mechanism resulting in increased expression of PGC1-alpha' S39-S39
Zeissler M, Carroll CB, Hanemann CO & Zajieck JP (2012) '108 Investigating the neuroprotective properties of Δ9-THC in a cell culture model of Parkinson's disease' BMJ e1.58-e1 , DOI
Hanemann CO, Ammoun S & Zhou L (2012) 'Emerging Therapeutic Targets in Merlin-Deficient Tumors' S18-S18
Shivane A, Hilton DA & Hanemann CO (2011) 'Acquired rippling muscle disease-report of two cases' 29-29
Ammoun S, Zhou L, Barczyk M, Hilton D, Hafizi S & Hanemann CO (2011) 'GAS6/AXL-FAMILY RECEPTORS IN SCHWANNOMA PATHOLOGICAL PROLIFERATION, ADHESION AND SURVIVAL' 1-1
Carroll C, Zajicek JP, Hanemann CO, Stone V & Zeissler M (2010) 'CANNABINOIDS ARE NEUROPROTECTIVE IN A HUMAN CELL CULTURE MODEL OF PARKINSON'S DISEASE' E60-E60 , DOI
Carroll C, Williams GJ, Chadborn NH, Hanemann CO, Zajicek JP, Morrison KE, Gibson K & Zeissler M (2010) 'CHANGES IN IRON-REGULATORY GENE EXPRESSION OCCUR IN HUMAN CELL CULTURE MODELS OF PARKINSON'S DISEASE' E29-E29 , DOI
Schmid MC, Zhou L, Ammoun S & Hanemann CO (2010) 'Targeting focal adhesion kinase (FAK) in primary human schwannoma' 42-42 , DOI
Krolikowski K, Hanemann O & Jones J (2010) 'TREACHEROUS TRIANGLE OF TUMOUR, SEIZURE AND STROKE' E39-E39 , DOI
Hanemann CO, Ammoun S, Schmid MC, Ristic N, Ercolano E & Zhou L (2010) 'IGF/IGFBP SIGNALING IN MERLIN-DEFICIENT TUMORS' 22-22
Ammoun S, Schmid MC & Hanemann CO (2009) 'Abstract C164: Targeting receptor tyrosine kinases and their downstream signaling pathways in human schwannoma' American Association for Cancer Research (AACR) C164-C164 , DOI
Carroll CB, Chadborn N, Hanemann O & Zajicek J (2009) 'CANNABINOIDS ARE NEUROPROTECTIVE IN A CELL CULTURE MODEL OF PARKINSON'S DISEASE' , DOI
Hanemann CO & Ammoun S (2009) 'MERLIN'S TUMOURS: FROM BENCH TO BEDSIDE' , DOI
George JS, Harikrishnan S, Ali I, Baresi R & Hanemann CO (2009) 'RIPPLING MUSCLE DISEASE IN ASSOCIATION WITH MYASTHENIA GRAVIS' , DOI
Imam I, Ball S, Wright D, Hanemann O & Zajicek J (2009) 'THE EPIDEMIOLOGY OF MOTOR NEURONE DISEASE IN TWO COUNTIES IN THE SOUTH WEST OF ENGLAND' , DOI
Doddrell R, Hanemann CO & Parkinson DB (2009) 'REGULATION OF CELL DIFFERENTIATION IN MERLIN NULL TUMOURS' S170-S170
Ammoun S, Cunliffe C, Allen JC, Zagzag D, Hanemann O & Karajannis M (2009) 'EGF RECEPTOR FAMILY ACTIVATION AND LAPATINIB IN VESTIBULAR SCHWANNOMA' 577-578
Zhang H, Hanemann O, Widmer M, Hosking R, Chadborn N, Zajicek J & Hilton DA (2009) 'Cannabinoid receptors expression in multiple sclerosis' 17-17
Ammoun S & Hanemann O (2007) 'Strong and long-lasting activation of ERK in human schwannoma cells' 258-259
Hanemann CO (2007) 'Pathobiology of schwannomas' 214-214
Flaiz C, Hanemann CO & Medimond (2007) 'Non-localised Rac1 and Cdc42 activation and protrusive activity in schwannoma, a benign tumour of the nervous system' 107-112
Flaiz C & Hanemann CO (2007) 'Non-localised Rac1 and Cdc42 activation and protrusive activity in schwannoma, a benign tumour of the nervous system' Proceedings of the Viii European Meeting on Glial Cells in Health and Disease 107-112
Munch C, Rosenbohm A, Sperfeld A, Meyer T, Hanemann O & Ludolph A (2006) 'Heterozygous R1101K mutation of the DCTN1 gene in a family with frontotemporal dementia and amyotrophic lateral sclerosis' S64-S64
Hanemann CO (2006) 'Insights from the development of Schwann cell tumours' S105-S106
Munch C, Rosenbohm A, Sperfeld AD, Uttner I, Reske S, Meyer T, Hanemann CO, Stumm G & Ludolph AC (2005) 'Heterozygous R1101K mutation of the DCTN1 gene in a family with amyotrophic lateral sclerosis and frontotemporal dementia' 18-18
Walter MC, Petersen JA, Stucka R, Fischer D, Schroder R, Vorgerd M, Schroers A, Schreiber H, Hanemann CO & Knirsch U (2004) 'FKRP (826C > A) frequently causes limb-girdle muscular dystrophy in German patients' 15-15
Munch C, Sperfeld AD, Meyer T, Prudlo J, Hanemann CO, Stumm G & Ludolph AC (2004) 'Point mutations of the p150 subunit of dynactin (DCTN1) and absence of mutations in the cytoplasmic dynein heavy chain (DNCHC1) gene in amyotrophic lateral sclerosis' 33-33
Hanemann CO & Ludolph AC (2003) 'ALS/MND meeting of the European ALS/MND group Reisenburg Castle 30 January - 1 February 2003' 121-122 , DOI
Zuchner S, Sperfeld AD, Senderek J, Sellhaus B, Hanemann CO & Schroder JM (2002) 'A novel nonsense mutation in the ABC1 gene causes a severe syringomyelia-like phenotype of Tangier disease' 577-578
Hanemann CO, Sperfeld AD, Hein C, Schroder JM & Ludolph AC (2002) 'Occurrence and characterisation of peripheral nerve involvement in neurofibromatosis type 2' S60-S60
Hanemann CO, Sperfeld AD, Karitzky J, Schreiber H, Brummer D, Haussler J & Ludolph AC (2002) 'X-linked bulbospinal neuronopathy Kennedy: Presence of known and unknown clinical features and electrophysiological investigation in 34 cases' S76-S77
Presentations and posters
Carroll CB, Zeissler ML, Stone V, Hanemann CO & Zajicek JP Carroll CB, Zeissler ML, Stone V, Hanemann CO & Zajicek JP 'Cannabinoids Are Neuroprotective in a Human Cell Culture Model of Parkinson's Disease' Author Site Open access
Ammoun S, Maze EA, Agit B, Belshaw R & Hanemann CO Ammoun S, Maze EA, Agit B, Belshaw R & Hanemann CO 'Abstract 1164: Human endogenous retrovirus type K promotes proliferation of Merlin negative schwannoma and meningioma which can be inhibited by anti-retroviral and anti-TEAD drugs' , DOI
Dave F, Ammoun S & Hanemann CO Dave F, Ammoun S & Hanemann CO 'Abstract 941: TAM receptors as potential therapeutic targets in NF2-related schwannomas and meningiomas' , DOI
Hanemann CO, Abdelrahman A, Adams C, Sahm F, Urbanic-Purkart T, Khalil M, Vergura R & Morelli C Hanemann CO, Abdelrahman A, Adams C, Sahm F, Urbanic-Purkart T, Khalil M, Vergura R & Morelli C 'BIOM-56. MIR-497 AND 219 IN BLOOD AID MENINGIOMA CLASSIFICATIONMIR-497 AND 219 IN BLOOD AID MENINGIOMA CLASSIFICATION' , DOI
Baiz D, Negroni C, Ferluga S, Ercolano E, Adams C & Hanemann CO Baiz D, Negroni C, Ferluga S, Ercolano E, Adams C & Hanemann CO 'Circulating miR-9 levels as a novel prognostic biomarker for highergrade meningioma' Open access
Akther Y, Dunn J, Adams C, Sharma V, Banton M & Hanemann C Akther Y, Dunn J, Adams C, Sharma V, Banton M & Hanemann C 'CSIG-27. PROTEOMIC ANALYSIS OF GENETICALLY STRATIFIED MENINGIOMA' , DOI
Hanemann CO & Na J Hanemann CO & Na J 'EXTH-90. HDAC INHIBITOR, CAY10603, IS A POTENT RADIOSENSITIZER IN MENINGIOMAS' , DOI
Negroni C, Ercolano E, Adams C, Baiz D, Kurian KM, Hilton D & Hanemann CO Negroni C, Ercolano E, Adams C, Baiz D, Kurian KM, Hilton D & Hanemann CO 'HIGH LEVELS OF GATA-4 IN MALIGNANT MENINGIOMA LEAD TO LOWER miR-497 similar to 195 CLUSTER EXPRESSION IN TISSUE AND BLOOD' Author Site
Hanemann CO, Maze E, Agit B, Reeves S, Hilton D, Parkinson DB, Laraba L, Ercolano E, Kurian K & Belshaw R Hanemann CO, Maze E, Agit B, Reeves S, Hilton D, Parkinson DB, Laraba L, Ercolano E, Kurian K & Belshaw R 'Human Endogenous Retrovirus Type K promotes proliferation of Merlin-negative schwannoma and meningioma which can be inhibited by anti-retroviral and anti-TEAD drugs' , DOI Open access
Ammoun S, Dave F, Hilton D, Adams C, Elcorano E, Hafizi S & Hanemann CO Ammoun S, Dave F, Hilton D, Adams C, Elcorano E, Hafizi S & Hanemann CO 'INVESTIGATING THE ROLE OF TAM FAMILY RECEPTORS IN MERLIN DEFICIENT TUMOURS' Author Site
Dunn J, Ferluga S, Lasonder E & Hanemann O Dunn J, Ferluga S, Lasonder E & Hanemann O 'GLOBAL PROTEOME AND PHOSPHOPROTEOME ANALYSIS OF MENINGIOMAS' Author Site , DOI Open access
Ferluga S, Baiz D, Dunn J, Hilton DA, Bassiri K, Sharma V, Adams C, Lasonder E & Hanemann C Ferluga S, Baiz D, Dunn J, Hilton DA, Bassiri K, Sharma V, Adams C, Lasonder E & Hanemann C 'PROTEOME AND PHOSPHOPROTEOME ANALYSIS IDENTIFIES STAT1 AS A NOVEL TARGET IN DIFFERENT GRADE MENINGIOMAS' Author Site , DOI Open access
di Bonaventura R, Young A, Zakaria R, Champeaux C, Foo A, Tonn J-C, McMurran C, Yeo TT, Kirsch M & Afshari F di Bonaventura R, Young A, Zakaria R, Champeaux C, Foo A, Tonn J-C, McMurran C, Yeo TT, Kirsch M & Afshari F 'MNGI-07. THE ANAPLASTIC MENINGIOMA INTERNATIONAL CONSORTIUM (AMICo) RETROSPECTIVE STUDY OF TREATMENT AND OUTCOME OF PATIENTS WITH ANAPLASTIC MENINGIOMAS' , DOI
Baiz D, Negroni C, Ercolano E, L Adams C, Kurian KM, A Hilton D & Hanemann OC Baiz D, Negroni C, Ercolano E, L Adams C, Kurian KM, A Hilton D & Hanemann OC 'A pilot study to establish non-invasive biomarkers for higher-grade meningioma' , DOI
Sofela AB & Hanemann O Sofela AB & Hanemann O 'Identifying novel molecular differences between WHO grade I and II meningiomas' , DOI
Akther Y, Adams C, Sharma V, Barros C, Banton M & Hanemann O Akther Y, Adams C, Sharma V, Barros C, Banton M & Hanemann O 'OPTC-1. Proteomic analysis of genetically stratified low-grade meningioma' , DOI
Hanemann CO, Dunn J, Akther Y, Ercolano E, Adams C, Banton M, Sharma V & Hilton D Hanemann CO, Dunn J, Akther Y, Ercolano E, Adams C, Banton M, Sharma V & Hilton D 'OS08.5.A Proteomic analysis of meningioma' , DOI
Hanemann CO, Dunn J, Ferluga S, Sharma V, Futschik M, Hilton D, Adams C & Lasonder E Hanemann CO, Dunn J, Ferluga S, Sharma V, Futschik M, Hilton D, Adams C & Lasonder E 'P02.09 Proteomic analysis of meningioma discovers new pathways and their activation including NEK9 and AKT' , DOI
Hanemann CO & Ferluga S Hanemann CO & Ferluga S 'P11.12 Analysis of the proteom and phoshoproteom of meningiomas' , DOI
Hanemann CO, Ferluga S, Baiz D, Sharma V, Adams CL, Bassiri K, Dunn J, Ercolano E, Kurian K & Hilton DA Hanemann CO, Ferluga S, Baiz D, Sharma V, Adams CL, Bassiri K, Dunn J, Ercolano E, Kurian K & Hilton DA 'P09.07 Constitutive activation of the EGFR-STAT1 axis increases proliferation of meningioma tumour cells' , DOI
Ferluga S, Baiz D, Dunn J, Hilton DA, Bassiri K, Sharma V, Adams C, Lasonder E & Hanemann C Ferluga S, Baiz D, Dunn J, Hilton DA, Bassiri K, Sharma V, Adams C, Lasonder E & Hanemann C 'P12.08 Proteome and phosphoproteome analysis identifies STAT1 as a novel target in different grade meningiomas' , DOI
Negroni C, Ercolano E, Adams C, Hilton D, Baiz D & Hanemann CO Negroni C, Ercolano E, Adams C, Hilton D, Baiz D & Hanemann CO 'PO-162 The transcription factor GATA4 is overexpressed in malignant meningioma enhancing proliferation via downregulation of miR-15 family members' , DOI
Dunn J, Hanemann O, Ferluga S, Lasonder E, Sharma V, Hilton D, Adams C & Futschik M Dunn J, Hanemann O, Ferluga S, Lasonder E, Sharma V, Hilton D, Adams C & Futschik M 'PO-522 Global proteome and phosphoprotein profiling of meningiomas reveals novel potential therapeutic targets and biomarkers' , DOI
Ferluga S, Dunn J, Lasonder E, Sharma V, Hilton DA, Adams C & Hanemann CO Ferluga S, Dunn J, Lasonder E, Sharma V, Hilton DA, Adams C & Hanemann CO 'Proteome and phosphoproteome analysis of stratified meningiomas' , DOI Open access
Akther Y, Adams C, Sharma V, Barros C, Banton M & Hanemann O Akther Y, Adams C, Sharma V, Barros C, Banton M & Hanemann O 'Proteomic analysis of genetically stratified low-grade meningioma' , DOI
Hanemann CO, Akther Y, Adams C, Sharma V & Banton M Hanemann CO, Akther Y, Adams C, Sharma V & Banton M 'Proteomic analysis of genetically stratified meningioma' , DOI
Hanemann CO, Dunn J, Ferluga S, Sharma V, Futschik M, Hilton D, Adams C & Lasonder E Hanemann CO, Dunn J, Ferluga S, Sharma V, Futschik M, Hilton D, Adams C & Lasonder E 'PROTEOMIC ANALYSIS OF MENINGIOMA DISCOVERS NEW PATHWAYS AND THEIR ACTIVATION INCLUDING NEK9 AND AKT' Author Site
Ferluga S, Baiz D, Ercolano E, Sharma V, Dunn J, Kurian KM, Hilton D & Hanemann CO Ferluga S, Baiz D, Ercolano E, Sharma V, Dunn J, Kurian KM, Hilton D & Hanemann CO 'TARGETING CONSTITUTIVE ACTIVATION OF THE EGFR-STAT1 AXIS DECREASES PROLIFERATION OF MENINGIOMA TUMOUR CELLS' Author Site
di Bonaventura R, Young A, Zakaria R, Champeaux C, Foo A, Tonn J-C, McMurran C, Yeo TT, Kirsch M & Afshari F di Bonaventura R, Young A, Zakaria R, Champeaux C, Foo A, Tonn J-C, McMurran C, Yeo TT, Kirsch M & Afshari F 'THE ANAPLASTIC MENINGIOMA INTERNATIONAL CONSORTIUM (AMICo) RETROSPECTIVE STUDY OF TREATMENT AND OUTCOME OF PATIENTS WITH ANAPLASTIC MENINGIOMAS' Author Site
Laraba L, Ferluga S, Ercolano E, Adams C, Shivane A, Edwards P, Futschik M, Lenis V, de Guibert JG & Moller S Laraba L, Ferluga S, Ercolano E, Adams C, Shivane A, Edwards P, Futschik M, Lenis V, de Guibert JG & Moller S 'The cancer stem cell marker ALDH1A1 is upregulated and drives proliferation in merlin null meningioma and schwannoma' Author Site
Rimmer JL, Baiz D, Ercolano E & Hanemann O Rimmer JL, Baiz D, Ercolano E & Hanemann O 'The potential of CRL4DCAF1 and KSR1 as therapeutic targets in merlin-deficient meningioma' , DOI Open access
Negroni C, Ercolano E, Adams C, Hilton D, Baiz D & Hanemann CO Negroni C, Ercolano E, Adams C, Hilton D, Baiz D & Hanemann CO 'The transcription factor GATA4 is overexpressed in malignant meningioma enhancing proliferation via downregulation of miR-15 family members' Open access
Other Publications
Maze EA, Agit B, Reeves S, Hilton DA, Parkinson DB, Laraba L, Ercolano E, Kurian KM, Hanemann CO & Belshaw RD Data from Human Endogenous Retrovirus Type K Promotes Proliferation and Confers Sensitivity to Antiretroviral Drugs in Merlin-Negative Schwannoma and Meningioma. , DOI
Maze EA, Agit B, Reeves S, Hilton DA, Parkinson DB, Laraba L, Ercolano E, Kurian KM, Hanemann CO & Belshaw RD Figure S1 from Human Endogenous Retrovirus Type K Promotes Proliferation and Confers Sensitivity to Antiretroviral Drugs in Merlin-Negative Schwannoma and Meningioma. , DOI
Maze EA, Agit B, Reeves S, Hilton DA, Parkinson DB, Laraba L, Ercolano E, Kurian KM, Hanemann CO & Belshaw RD Figure S1 from Human Endogenous Retrovirus Type K Promotes Proliferation and Confers Sensitivity to Antiretroviral Drugs in Merlin-Negative Schwannoma and Meningioma. , DOI
Maze EA, Agit B, Reeves S, Hilton DA, Parkinson DB, Laraba L, Ercolano E, Kurian KM, Hanemann CO & Belshaw RD Figure S2 from Human Endogenous Retrovirus Type K Promotes Proliferation and Confers Sensitivity to Antiretroviral Drugs in Merlin-Negative Schwannoma and Meningioma. , DOI
Maze EA, Agit B, Reeves S, Hilton DA, Parkinson DB, Laraba L, Ercolano E, Kurian KM, Hanemann CO & Belshaw RD Figure S2 from Human Endogenous Retrovirus Type K Promotes Proliferation and Confers Sensitivity to Antiretroviral Drugs in Merlin-Negative Schwannoma and Meningioma. , DOI
Maze EA, Agit B, Reeves S, Hilton DA, Parkinson DB, Laraba L, Ercolano E, Kurian KM, Hanemann CO & Belshaw RD Figure S3 from Human Endogenous Retrovirus Type K Promotes Proliferation and Confers Sensitivity to Antiretroviral Drugs in Merlin-Negative Schwannoma and Meningioma. , DOI
Maze EA, Agit B, Reeves S, Hilton DA, Parkinson DB, Laraba L, Ercolano E, Kurian KM, Hanemann CO & Belshaw RD Figure S3 from Human Endogenous Retrovirus Type K Promotes Proliferation and Confers Sensitivity to Antiretroviral Drugs in Merlin-Negative Schwannoma and Meningioma. , DOI
Maze EA, Agit B, Reeves S, Hilton DA, Parkinson DB, Laraba L, Ercolano E, Kurian KM, Hanemann CO & Belshaw RD Figure S4 from Human Endogenous Retrovirus Type K Promotes Proliferation and Confers Sensitivity to Antiretroviral Drugs in Merlin-Negative Schwannoma and Meningioma. , DOI
Maze EA, Agit B, Reeves S, Hilton DA, Parkinson DB, Laraba L, Ercolano E, Kurian KM, Hanemann CO & Belshaw RD Figure S4 from Human Endogenous Retrovirus Type K Promotes Proliferation and Confers Sensitivity to Antiretroviral Drugs in Merlin-Negative Schwannoma and Meningioma. , DOI
Maze EA, Agit B, Reeves S, Hilton DA, Parkinson DB, Laraba L, Ercolano E, Kurian KM, Hanemann CO & Belshaw RD Figure S5 from Human Endogenous Retrovirus Type K Promotes Proliferation and Confers Sensitivity to Antiretroviral Drugs in Merlin-Negative Schwannoma and Meningioma. , DOI
Maze EA, Agit B, Reeves S, Hilton DA, Parkinson DB, Laraba L, Ercolano E, Kurian KM, Hanemann CO & Belshaw RD Figure S5 from Human Endogenous Retrovirus Type K Promotes Proliferation and Confers Sensitivity to Antiretroviral Drugs in Merlin-Negative Schwannoma and Meningioma. , DOI
Maze EA, Agit B, Reeves S, Hilton DA, Parkinson DB, Laraba L, Ercolano E, Kurian KM, Hanemann CO & Belshaw RD Figure S6 from Human Endogenous Retrovirus Type K Promotes Proliferation and Confers Sensitivity to Antiretroviral Drugs in Merlin-Negative Schwannoma and Meningioma. , DOI
Maze EA, Agit B, Reeves S, Hilton DA, Parkinson DB, Laraba L, Ercolano E, Kurian KM, Hanemann CO & Belshaw RD Figure S6 from Human Endogenous Retrovirus Type K Promotes Proliferation and Confers Sensitivity to Antiretroviral Drugs in Merlin-Negative Schwannoma and Meningioma. , DOI
Maze EA, Agit B, Reeves S, Hilton DA, Parkinson DB, Laraba L, Ercolano E, Kurian KM, Hanemann CO & Belshaw RD Figure S7 from Human Endogenous Retrovirus Type K Promotes Proliferation and Confers Sensitivity to Antiretroviral Drugs in Merlin-Negative Schwannoma and Meningioma. , DOI
Maze EA, Agit B, Reeves S, Hilton DA, Parkinson DB, Laraba L, Ercolano E, Kurian KM, Hanemann CO & Belshaw RD Figure S7 from Human Endogenous Retrovirus Type K Promotes Proliferation and Confers Sensitivity to Antiretroviral Drugs in Merlin-Negative Schwannoma and Meningioma. , DOI
Maze EA, Agit B, Reeves S, Hilton DA, Parkinson DB, Laraba L, Ercolano E, Kurian KM, Hanemann CO & Belshaw RD Supplementary Table 1 from Human Endogenous Retrovirus Type K Promotes Proliferation and Confers Sensitivity to Antiretroviral Drugs in Merlin-Negative Schwannoma and Meningioma. , DOI
Maze EA, Agit B, Reeves S, Hilton DA, Parkinson DB, Laraba L, Ercolano E, Kurian KM, Hanemann CO & Belshaw RD Supplementary Table 1 from Human Endogenous Retrovirus Type K Promotes Proliferation and Confers Sensitivity to Antiretroviral Drugs in Merlin-Negative Schwannoma and Meningioma. , DOI
Maze EA, Agit B, Reeves S, Hilton DA, Parkinson DB, Laraba L, Ercolano E, Kurian KM, Hanemann CO & Belshaw RD Supplementary Table 2 from Human Endogenous Retrovirus Type K Promotes Proliferation and Confers Sensitivity to Antiretroviral Drugs in Merlin-Negative Schwannoma and Meningioma. , DOI
Maze EA, Agit B, Reeves S, Hilton DA, Parkinson DB, Laraba L, Ercolano E, Kurian KM, Hanemann CO & Belshaw RD Supplementary Table 2 from Human Endogenous Retrovirus Type K Promotes Proliferation and Confers Sensitivity to Antiretroviral Drugs in Merlin-Negative Schwannoma and Meningioma. , DOI
Maze EA, Agit B, Reeves S, Hilton DA, Parkinson DB, Laraba L, Ercolano E, Kurian KM, Hanemann CO & Belshaw RD Supplementary Table 3 from Human Endogenous Retrovirus Type K Promotes Proliferation and Confers Sensitivity to Antiretroviral Drugs in Merlin-Negative Schwannoma and Meningioma. , DOI
Maze EA, Agit B, Reeves S, Hilton DA, Parkinson DB, Laraba L, Ercolano E, Kurian KM, Hanemann CO & Belshaw RD Supplementary Table 3 from Human Endogenous Retrovirus Type K Promotes Proliferation and Confers Sensitivity to Antiretroviral Drugs in Merlin-Negative Schwannoma and Meningioma. , DOI