Mammal tissue under a microscope
Environmental hepatology is a rapidly emerging discipline that examines how the environments we live in – our air, water, soil, diet, and consumer products – influence liver health across the lifespan. At Plymouth, we are pioneering this field by investigating how real-world environmental exposures, including pollutants such as micro- and nanoplastics (MNPs), interact with the liver alongside established contributors to disease (including alcohol, metabolic dysfunction, dietary factors, carcinogens, viral hepatitis, and autoimmune processes) to drive inflammation, fibrosis, metabolic impairment, and cancer.
The Centre of Environmental Hepatology (CEH) brings together scientists, clinicians and environmental researchers to generate mechanistic, clinically grounded evidence that can inform prevention, improve patient outcomes, and support policies that reduce harmful exposures. Our mission is to transform understanding of liver health in a changing world and to ensure that research translates into meaningful impact for patients, communities, and future generations.

Environmental hepatology recognises that liver disease emerges from the interplay between biology, behaviour and the environments that surround us.

By bringing these dimensions together, our work aims to generate evidence that improves prevention, informs policy and ultimately protects liver health by uncovering the effects of modern environmental exposures in a rapidly changing world.

Shilpa ChokshiProfessor Shilpa Chokshi
Professor of Experimental Hepatology and Director of Centre of Environmental Hepatology

 
 

Research team

 
 
 

In the news

About half of those living with alcohol-related liver disease are obese, and the combination of alcohol consumption and obesity can speed up liver damage and death
Could weight loss drug benefit patients living with alcohol addiction, liver disease and obesity?

A four-year £2.7million research project will investigate whether Semaglutide could become the first treatment to address these problems together

20 August 2026
 
 

Centre achievements

 
 
 
 
 
 
 
 
 
 

Related courses

Studentship open to applications

Project SHIELD: Systematic assessment of Hepatic micro- and nanoplastIc accumulatIon and clEarance in Liver Disease

The studentships will start on: 1 January 2027
The deadline for applications is: 16 October 2026, 12 midday (UK time)
This fully funded competitively awarded PhD project will define the burden, characteristics and hepatobiliary fate of MNPs across the spectrum of metabolic dysfunction-associated steatotic liver disease (MASLD) while developing urgently needed biological reference materials to standardise MNP detection.
Hepatocyte with nanoplastic accumulation
 
 

Vacancy: Post-Doctoral Research Fellow

Application deadline: 11 October 2026, 12 midnight (UK time)
Help uncover how plastic pollution may be contributing to the global rise in liver disease and join a pioneering research team at the forefront of environmental hepatology.
We are seeking a talented and motivated Postdoctoral Research Fellow to join the Centre for Environmental Hepatology. This fully funded two-year position offers a unique opportunity to contribute to internationally significant research exploring how environmental pollutants, particularly micro- and nanoplastics, impact liver health and disease.
 
 

Get involved

Student opportunities
Research placements, dissertation projects and volunteering roles are available for students in medicine, biomedical sciences and environmental sciences.
Seminars and events
All are welcome to attend our monthly CEH Seminar Series featuring national and international speakers.
Take part in research
We periodically recruit volunteers for studies on environmental exposures and liver health. 
Collaborate with us
We welcome collaborations with researchers, clinicians, industry partners, policymakers and environmental organisations.
Training and careers
Information on PhD studentships, fellowships and research posts will be posted as opportunities arise.
Please register your interest if you would like to be contacted about any of these opportunities.
Medical students using the Anatomage room