Centre of Environmental Hepatology
Investigating how environmental exposures drive liver disease
Environmental hepatology recognises that liver disease emerges from the interplay between biology, behaviour and the environments that surround us.
Professor Shilpa Chokshi
Professor of Experimental Hepatology and Director of Centre of Environmental Hepatology
The BOOST trial will assess whether the HMB supplement can benefit some of the 60,000 people living with the liver condition in the UK
Collaboration between University and Trust hopes to make it easier to predict worst cases
xEstablished a dedicated environmental hepatology laboratory fully equipped to support mechanistic, toxicological and translational liver research
SBuilt a fully operational clinical research pipeline that enables access to patient samples and liver tissue and supports environmentally focused studies within NHS pathways
ËRecruited a multidisciplinary research team including postdoctoral scientists, clinical fellows and PhD students contributing expertise across hepatology, environmental science and analytical methodologies
1Secured competitive funding from the Peninsula Medical Foundation to accelerate early-stage research, capability development and infrastructure growth
ÊLaunched cross-disciplinary collaborations with colleagues in environmental science, analytical chemistry, microbiology and clinical hepatology across the University of Plymouth and University Hospitals Plymouth
BDeveloped advanced human-relevant experimental platforms including precision cut liver slices, liver organoids and multimodal imaging workflows for studying real-world exposures
ÆCreated a seminar and training programme to support skills development, knowledge exchange and capacity building in environmental hepatology
<Strengthened national and international partnerships contributing to the global scientific effort investigating micro- and nanoplastics and their effects on liver health
,Laid the foundations for major external funding applications to UK and European research bodies to advance mechanistic and translational environmental hepatology









