Peninsula Clinical Trials Unit: Study Portfolio

Title: A novel way to understand and communicate the burden of Antipsychotic Prescribing for Adults across Specialist Intellectual Disability Services in England and Wales

Chief Investigator: Professor Rohit Shankar, Faculty of Health, University of Plymouth

Title: D-PACT: Dementia PersonAlised Care Team 

Chief Investigator: Professor Richard Byng, Faculty of Health, University of Plymouth

Title: Realist informed mixed methods evaluation of the Dementia-Personalised Aligned Care Team intervention (D-PACT): a complex intervention for individuals with dementia and carers

Chief Investigator: Professor Richard Byng, Faculty of Health, University of Plymouth

Title: EMaPP - Evaluating the Management of chronic Pelvic girdle Pain following pregnancy: A randomised controlled feasibility trialP trial  

Chief Investigator: Professor Jenny Freeman, Faculty of Health, University of Plymouth

Title: Randomised, Phase II open label study of Rituximab/Ibritinib vs Rituximab/Chemo in older patients with mantle cell lymphoma

Chief Investigator: Dr David Lewis, University Hospitals Plymouth NHS Trust

CRUK  ISRCTN11038174

Title: Establishing a biobank and database as a national resource for characterising indolent and aggressive forms of mantle cell lymphoma.

Chief Investigator: Professor Simon Rule, University Hospitals Plymouth NHS Trust

Title: Functional imagery training to reduce alcohol-related harm in patients with alcohol-related liver disease: a pilot randomised trial.

Chief Investigator: Dr Ashwin Dhanda, University Hospitals Plymouth NHS Trust

Title: A randomized phase II trial evaluating Ibrutinib plus CD20 Ab and Ibrutinib-Venetoclax plus CD20 Ab in patients with untreated mantle cell lymphoma.

Chief Investigator: Professor Steven Le Gouill, Institut Curie – Paris

Associate Coordinating Investigator: Dr David Lewis, University Hospitals Plymouth NHS Trust

Title: Developing an occupation-based complex intervention for living well with anxiety in Parkinson's.

Chief Investigator: Chris Lovegrove, Royal Devon & Exeter NHS Foundation Trust/ University of Plymouth

Title: To understand the outcome and mortality of hospital admission with COVID-19 in people with Parkinson’s disease and atypical parkinsonian syndromes (PD/APS), to inform patients and future design of health, social care and charity services.

Chief Investigator: Professor Camille Carroll, Faculty of Health, University of Plymouth

Title: How are treatment outcomes for people with severe obesity ImPROved by GROUP-based behavioural intervention? 

Chief Investigator: Professor Jonathan Pinkney, Faculty of Health, University of Plymouth

Title: Older people with intellectual disabilities and epilepsy – recognising and correcting anticholinergic inducing polypharmacy

Chief Investigator: Professor Rohit Shankar, Faculty of Health, University of Plymouth

Title: Neuropsychiatric Research Register for people with Intellectual Disabilities and Epilepsy

Chief Investigator: Professor Rohit Shankar, Faculty of Health, University of Plymouth

Title: Reducing SteatOsis Prior to Liver Resection – A feasibility multi-centre randomised controlled trial to test if a pre-operative two-week very low-calorie diet with dietitian education and support reduces intra-operative blood loss and improves post-operative outcomes following liver surgery, compared with a control group

Chief Investigator: Mr Somaiah Aroori, Faculty of Health, University of Plymouth

Title: The Efficacy of Peroneal Nerve Functional Electrical STimulation (FES) for the Reduction of Bradykinesia in Parkinson’s DiSease: An Assessor Blinded Randomised Controlled Trial

Chief Investigator: Professor Paul Taylor, Salisbury NHS Foundation Trust

Title: The South West Impact of Multiple Sclerosis (SWIMS) project – a patient-orientated longitudinal study of the impact of multiple sclerosis in South West England.

Chief Investigator: Professor Jeremy Hobart, Faculty of Health, University of Plymouth

This unit receives National Institute for Health and Care Research CTU Support Funding. This funding has been awarded to support the unit in developing and supporting NIHR trials.