Mathew Upton

Academic profile

Professor Mathew Upton

Professor of Medical Microbiology
School of Biomedical Sciences (Faculty of Health)

The Global Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Mathew's work contributes towards the following SDG(s):

Goal 03: SDG 3 - Good Health and Well-beingGoal 09: SDG 9 - Industry, Innovation, and Infrastructure

About Mathew

August 2018 – Professor of Medical Microbiology, University of Plymouth

June 2018 – Founder and Chief Scientific Officer at Amprologix Ltd (@amprologix)

April 2014 – July 2022 Co-founder and Director at Spectromics Ltd (http://www.spectromics.com/)

May 2013 – Reader in Medical Microbiology, University of Plymouth

June 2011 – Senior Lecturer in Medical Microbiology, University of Manchester

June 2001 – Lecturer in Medical Microbiology, University of Manchester

Following BSc and PhD studies in Newcastle, I completed a number of postdoc projects in Aberdeen, Antarctica, Bristol, Liverpool and New Zealand, before taking up a lectureship in Manchester.

Lead for  Antibiotic Resistant Pathogens Research Group

Current lab members:

  • Dr Grant January (PDRA) – Newton Fund/MRC/SAMRC – South Africa-UK Antibiotic Accelerator
  • Dr Katie Muddiman - Senior Technician in AMR
  • Sophie Tauber (PhD candidate, 2023-2027) - Developing a novel vaccine for Group B Streptococcus
  • Sean Kelly (PhD candidate, 2021-2027) - Emerging human respiratory pathogens
  • Tj Marnoch (ResM candidate) - The oral microbiome as a source of novel antimicrobials
  • Darshana Srivastava (PhD candidate 2023-2027) - co-supervision with Dr Phil Warburton) 
  • Josie Prole (PhD candidate 2024-2028) - co-supervision with Dr Lee Hutt)
  • Trudie McComb (PhD candidate 2024-2028) - co-supervision with Dr Matt Banton)

Supervised Research Degrees

I have supervised nearly 30 PhD students and over 70 MSc research projects. These projects have all been in the field of medical microbiology and have involved collaborators at UK universities, UKHSA (formerly Public Health England & HPA) and NHS Trusts.

Recent PhD Graduates (Director of studies)

  • Neil Powell (2020-2024) - Penicillin allergy patient classification
  • Jack Kay (2020-2023) - Discovery and design of of novel antimicrobial peptides
  • Matthew Koch (2017-2021) - SfAM PhD Studentship Discovery of novel antimicrobials from deep sea sponges
  • Abdu Aldarhami (2015-2019) - Novel antimicrobials for therapy of Gram positive infections
  • Nizar Saeedi (2014-2018) - Pathogenenesis of ST127 uropathogenic E coli
  • Rob O'Hara (2015-2018) - Epidemiology of ST127 uropathogenic E coli


Recent PhD Graduates (co-supervisor)

  • Jazmin Conway (2021-2024) - Marine biodiscovery for AMR
  • Kudzai Hwengwere (2021-2025) - Antarctic marine microbial ecology and natural product discovery
  • James Butler (2018-2022) - Novel antimicrobial surfaces to reduce healthcare associated infections
  • Poppy Best (2017-2021) - Bioactivity and ecology of bacteria from deep sea sponges
  • Sam Gould (2015-2018) - 3D models to study oral infections
  • Connor Wood (2015-2018) - Superinfection of influenza virus
  • Barbara Durante (2015-2018) - Immunological effects of antimicrobial peptides

Teaching

Areas of teaching interest relate to medical microbiology, bacterial genomics and antibiotic resistance.
MSc Biomedical Sciences
Contributing to modules BIOM5003 (Contemporary Aspects of Infection and Immunity), BIOM5005 (Project Design and Development), BIOM5006 (Research Project), BIOM5008 (Clinical Microbiology), BIOM5010 (Personalised Medicine).
BSc Biomedical Sciences.
Contributing to Modules BIOM3001, BIOM3003, BIOM3015, BIOM3016.