Medical Statistics: selected publications

2021

Parkash V, Ashwin H, Sadlova J, Vojtkova B, Jones G, Martin N, Greensted E, Allgar V, Kamhawi S, Valenzuela J.G, Layton A.M, Jaffe C.L, Volf P, Kaye P.M, Lacey C.J.N, 2021 'A clinical study to optimise a sand fly biting protocol for use in a controlled human infection model of cutaneous leishmaniasis (the FLYBITE study)' [version 1; peer review:awaiting peer review] Wellcome Open Research DOI

Plappert H, Hobson-Merrett C, Gibbons B, Baker E, Bevan S, Clark M, Creanor S, Davies L, Denyer R, Frost J, Gask L, Gibson J, Gill L, Gwernan-Jones R, Hardy P, Hosking J, Huxley P, Jeffrey A, Jones B, Marwaha S, Pinold V, Planner C, Rawcliffe T, Reilly S, Richards D, Williams L, Birchwood M, Byng R 2021 'Evaluation of a primary care-based collaborative care model (PARTNERS2) for people with diagnoses of schizophrenia, bipolar, or other psychoses: study protocol for a cluster randomised controlled trial' BJGP Open, DOI

Phillips H, Wright B, Allgar V, McConachie H, Sweetman J, Hargate R, Hodkinson R, Bland M, George H & Hughes A 2021 'Adapting and validating the Autism Diagnostic Observation Schedule Version 2 for use with deaf children and young people' Journal of Autism and Developmental Disorders, DOI

Jassam N, Barth JH, Allgar V, Glover S, Stevenson F, Lauber N, Houghton V, Hanif Z, Child J & Clark B 2021 'Evaluation of the MP Rapid 2019-NCOV IgM/IgG combo POCT test vs. an established platform-based method' Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 000456322199555-000456322199555, DOI

Ferguson D, Harwood P, Allgar V, Roy A, Foster P, Taylor M, Moulder E & Sharma H 2021 'The PINS Trial: a prospective randomized clinical trial comparing a traditional versus an emollient skincare regimen for the care of pin-sites in patients with circular frames' The Bone & Joint Journal 103-B, (2) 279-285, DOI

Clark J, Amoakwa E, Wright-Hughes A, Blenkinsopp J, Currow DC, Meads D, Farrin A, Allgar V, Macleod U & Johnson M 2021 'A cluster randomised trial of a Needs Assessment Tool for adult Cancer patients and their carers (NAT-C) in primary care: A feasibility study' PLOS ONE 16, (1) e0245647-e0245647, DOI

Wright N, Allgar V, Hankins F & Hearty P 2021 'Long-term Condition Management for Prisoners: exploring prevalence and compliance with national monitoring processes' Qeios, DOI

Husain SA, Husain SA, Khan OU, D’Cruz L & Allgar V 2021 'Review of hygiene adaptations among UK doctors in controlling the spread of SARS-CoV-2 infection' Clinical Medicine 21, (1) e20-e25, DOI

Tomlinson DR, Biscombe K, True J, Hosking J & Streeter AJ 2021 'Identification of deliberate catheter motion at the left atrial posterior wall during pulmonary vein isolation: Validity of respiratory motion adjustment' Journal of Cardiovascular Electrophysiology 32, (4) 994-1004, DOI

Redfern KM, Hollands HJ, Hosking J, Welch CR, Pinkney JH & Rees GA 2021 'The relationship between gestational weight gain, maternal upper-body subcutaneous fat changes and infant birth size: a pilot observational study amongst women with obesity' Early Human Development 154, (0) 105307-105307, DOI Open access

Reuben A, Appelboam A, Stevens KN, Vickery J, Ewings P, Ingram W, Jeffery AN, Body R, Hilton M & Coppell J 2021 'The Use of Tranexamic Acid to Reduce the Need for Nasal Packing in Epistaxis (NoPAC): Randomized Controlled Trial' Annals of Emergency Medicine, DOI Open access

Swords CE, Wong, BA JJ, Stevens KN, Psaltis AJ, Wormald PJ & Tan NC-W 2021 'The Use of Postoperative Antibiotics Following Endoscopic Sinus Surgery for Chronic Rhinosinusitis: A Systematic Review and Meta-analysis' American Journal of Rhinology & Allergy 194589242198914-194589242198914, DOI Open access

Gunn H, Stevens KN, Creanor S, Andrade J, Paul L, Miller L, Green C, Ewings P, Barton A & Berrow M 2021 'Balance Right in Multiple Sclerosis (BRiMS): a feasibility randomised controlled trial of a falls prevention programme' Pilot and Feasibility Studies 7, (1), DOI Open access

Tomlinson DR, Biscombe K, True J, Hosking J & Streeter AJ 2021 'Identification of deliberate catheter motion at the left atrial posterior wall during pulmonary vein isolation: Validity of respiratory motion adjustment' Journal of Cardiovascular Electrophysiology 32, (4) 994-1004, DOI

Rodgers LR, Streeter AJ, Lin N, Hamilton W & Henley WE 2021 'Impact of influenza vaccination on amoxicillin prescriptions in older adults: A retrospective cohort study using primary care data' PLOS ONE 16, (1) e0246156-e0246156, DOI

2020

Wright B, Phillips H, Le Couteur A, Sweetman J, Hodkinson R, Ralph-Lewis A, Hayward E, Brennan A, Mulloy J & Day N 2020 'Modifying and validating the social responsiveness scale edition 2 for use with deaf children and young people' PLOS ONE 15, (12) e0243162-e0243162, DOI

Beresford B, Mukherjee S, Mayhew E, Heavey E, Park A-L, Stuttard L, Allgar V & Knapp M 2020 'Evaluating specialist autism teams’ provision of care and support for autistic adults without learning disabilities: the SHAPE mixed-methods study' Health Services and Delivery Research 8, (48) 1-200, DOI

Van Der Feltz-Cornelis CM, Varley D, Allgar VL & de Beurs E 2020 'Workplace Stress, Presenteeism, Absenteeism, and Resilience Amongst University Staff and Students in the COVID-19 Lockdown' Frontiers in Psychiatry 11, DOI

Baldwin H, Biehal N, Allgar V, Cusworth L & Pickett K 2020 'Antenatal risk factors for child maltreatment: Linkage of data from a birth cohort study to child welfare records' Child Abuse & Neglect 107, 104605-104605, DOI

Wright B, Teige C, Watson J, Hodkinson R, Marshall D, Varley D, Allgar V, Mandefield L, Parrott S & Kingsley E 2020 'Autism Spectrum Social Stories In Schools Trial 2 (ASSSIST2): study protocol for a randomised controlled trial analysing clinical and cost-effectiveness of Social Stories™ in primary schools' BMC Psychology 8, (1), DOI

Jassam N, Hayden K, Dearman R, Allgar V & Barth JH 2020 'Prospective study comparing the outcome of a population-specific adjusted calcium equation to ionized calcium' Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 57, (4) 316-324, DOI

Wright B, Garside M, Allgar V, Hodkinson R & Thorpe H 2020 'A large population-based study of the mental health and wellbeing of children and young people in the North of England' Clinical Child Psychology and Psychiatry 25, (4) 877-890, DOI

White C, Noble S, Swan F, Watson M, Allgar V, Napier E, Nelson A & Johnson MJ 2020 '‘Hospice inpatient deep vein thrombosis detection (HIDDen) in advanced non-malignant diseases’: a longitudinal pilot study' BMJ Supportive & Palliative Care, DOI

Kemppinen A, Howell C, Allgar V, Dodd M, Gregson J, Knowles C, McLaughlin J, Pandya P, Whorwell P & Markaryan E 2020 'Randomised, double-blind, placebo controlled multi-centre study to assess the efficacy, tolerability and safety of Enterosgel® in the treatment of irritable bowel syndrome with diarrhoea (IBS-D) in adults' Trials 21, (1), DOI

Smith N, Abernethy C, Allgar V, Foster L, Martinson V & Stones E 2020 'An open‐label, randomised controlled trial on the effectiveness of the Orve + wrap ® versus Forced Air Warming in restoring normothermia in the postanaesthetic care unit' Journal of Clinical Nursing 29, (7-8) 1085-1093, DOI

Boland EG, Bennett MI, Allgar V & Boland JW 2020 'Cannabinoids for adult cancer-related pain: systematic review and meta-analysis' BMJ Supportive & Palliative Care 10, (1) 14-24, DOI

Marincowitz C, Lecky FE, Allgar V, Hutchinson P, Elbeltagi H, Johnson F, Quinn E, Tarantino S, Townend W & Kolias AG 2020 'Development of a Clinical Decision Rule for the Early Safe Discharge of Patients with Mild Traumatic Brain Injury and Findings on Computed Tomography Brain Scan: A Retrospective Cohort Study' Journal of Neurotrauma 37, (2) 324-333, DOI

Gadoud A, Kane E, Oliver SE, Johnson MJ, Macleod U & Allgar V 2020 'Palliative care for non-cancer conditions in primary care: a time trend analysis in the UK (2009–2014)' BMJ Supportive & Palliative Care, DOI

Bhandari S, Allgar V, Lamplugh A, Macdougall IC & Kalra PA 2020 'Protocol and Baseline Data of a Multicentre Prospective Double-Blinded Randomized Study of Intravenous Iron on Functional Status in Patients with Chronic Kidney Disease' American Journal of Nephrology 51, (6) 493-500, DOI

McKenzie R, Dallos R, Stedmon J, Hancocks H, Vickery PJ, Barton A, Vassallo T, Myhill C, Chynoweth J & Ewings P 2020 'SAFE, a new therapeutic intervention for families of children with autism: a randomised controlled feasibility trial' BMJ Open 10, (12) e038411-e038411 Publisher Site, DOI Open access

Taylor A, Thompson TP, Ussher M, Aveyard P, Murray RL, Harris T, Creanor S, Green C, Streeter AJ & Chynoweth J 2020 'Randomised controlled trial of tailored support to increase physical activity and reduce smoking in smokers not immediately ready to quit: protocol for the Trial of physical Activity-assisted Reduction of Smoking (TARS) Study' BMJ OPEN 10, (12) Author Site Publisher Site, DOI Open access

Chynoweth J, Hosking J, Jeffery A & Pinkney J 2020 'Contrasting impact of androgens on male and female adiposity, fat distribution and insulin resistance in childhood and adolescence (EarlyBird 75)' Pediatric Obesity 15, (12) 0-0, DOI Open access

Cominetti O, Hosking J, Jeffery A, Pinkney J & Martin F-P 2020 'Contributions of Fat and Carbohydrate Metabolism to Glucose Homeostasis in Childhood Change With Age and Puberty: A 12-Years Cohort Study (EARLYBIRD 77)' Frontiers in Nutrition 7, 0-0, DOI

Dennett R, Madsen LT, Connolly L, Hosking J, Dalgas U & Freeman J 2020 'Adherence and drop-out in randomized controlled trials of exercise interventions in people with multiple sclerosis: A systematic review and meta-analyses' Multiple Sclerosis and Related Disorders 43, 102169-102169, DOI Open access

Mullin S, Smith L, Lee K, D’Souza G, Woodgate P, Elflein J, Hällqvist J, Toffoli M, Streeter A & Hosking J 2020 'Ambroxol for the Treatment of Patients With Parkinson Disease With and Without Glucocerebrosidase Gene Mutations' JAMA Neurology, DOI Open access

Carayol J, Hosking J, Pinkney J, Marquis J, Charpagne A, Metairon S, Jeffery A, Hager J & Martin F-P 2020 'Genetic Susceptibility Determines β-Cell Function and Fasting Glycemia Trajectories Throughout Childhood: A 12-Year Cohort Study (EarlyBird 76)' Diabetes Care 43, (3) 653-660, DOI Open access

Cottey L, Roberts T, Graham B, Horner D, Stevens K, Enki D, Lyttle MD & Latour J 2020 'Need for recovery amongst emergency physicians in the UK and Ireland: a cross-sectional survey' BMJ Open 0-0, DOI Open access

Taylor A, Taylor RS, Ingram W, Dean SG, Jolly K, Mutrie N, Lambert J, Yardley L, Streeter A & Greaves C 2020 'Randomised controlled trial of an augmented exercise referral scheme using web-based behavioural support for inactive adults with chronic health conditions: the e-coachER trial' Br J Sports Med Author Site Publisher Site Open access

Taylor AH, Taylor RS, Ingram WM, Anokye N, Dean S, Jolly K, Mutrie N, Lambert J, Yardley L & Greaves C 2020 'Adding web-based behavioural support to exercise referral schemes for inactive adults with chronic health conditions: the e-coachER RCT' Health Technology Assessment 24, (63) 1-106, DOI Open access

2019

Boland JW, Allgar V, Boland EG, Bennett MI, Kaasa S, Hjermstad MJ & Johnson M 2019 'The relationship between pain, analgesics and survival in patients with advanced cancer; a secondary data analysis of the international European palliative care Cancer symptom study' European Journal of Clinical Pharmacology 76, (3) 393-402, DOI

Wright B, Tindall L, Hargate R, Allgar V, Trépel D & Ali S 2019 'Computerised cognitive–behavioural therapy for depression in adolescents: 12-month outcomes of a UK randomised controlled trial pilot study' BJPsych Open 6, (1), DOI

Sheridan R, Oliver SE, Hall G, Allgar V, Melling P, Bolton E, Atkin K, Denton D, Forbes S & Green T 2019 'Patient non-attendance at urgent referral appointments for suspected cancer and its links to cancer diagnosis and one year mortality: A cohort study of patients referred on the Two Week Wait pathway' Cancer Epidemiology 63, 101588-101588, DOI

Jefferson L, Atkin K, Sheridan R, Oliver S, Macleod U, Hall G, Forbes S, Green T, Allgar V & Knapp P 2019 'Non-attendance at urgent referral appointments for suspected cancer: a qualitative study to gain understanding from patients and GPs' Br J Gen Pract Author Site, DOI

Leese HJ, Sathyapalan T, Allgar V, Brison DR & Sturmey R 2019 'Going to extremes: the Goldilocks/Lagom principle and data distribution' BMJ Open 9, (11) e027767-e027767, DOI

Hodiamont F, Allgar V, Currow DC & Johnson MJ 2019 'Mental wellbeing in bereaved carers: A Health Survey for England population study' BMJ Supportive & Palliative Care, DOI

Johnson MJ, Cockayne S, Currow DC, Bell K, Hicks K, Fairhurst C, Gabe R, Torgerson D, Jefferson L & Oxberry S 2019 'Oral modified release morphine for breathlessness in chronic heart failure: a randomized placebo‐controlled trial' ESC Heart Failure 6, (6) 1149-1160, DOI

Swan F, English A, Allgar V, Hart SP & Johnson MJ 2019 'Authors' Response' Journal of Pain and Symptom Management 58, (2) e2-e3, DOI

Gilbert C, Allgar V & Doran T 2019 'Workload impact of the Quality and Outcomes Framework for patients with diabetes: an interrupted time series in general practice' British Journal of General Practice 69, (685) e570-e577, DOI

Barbetta C, Allgar V, Maddocks M, Ribeiro C, Wilcock A, Currow DC, Phillips J & Johnson MJ 2019 'Australia-modified Karnofsky Performance Scale and physical activity in COPD and lung cancer: an exploratory pooled data analysis' BMJ Supportive & Palliative Care, DOI

Kirby N, Wright B & Allgar V 2019 'Child mental health and resilience in the context of socioeconomic disadvantage: results from the Born in Bradford cohort study' European Child & Adolescent Psychiatry 29, (4) 467-477, DOI

Swan F, English A, Allgar V, Hart SP & Johnson MJ 2019 'The Hand-Held Fan and the Calming Hand for People With Chronic Breathlessness: A Feasibility Trial' Journal of Pain and Symptom Management 57, (6) 1051-1061.e1, DOI

Marincowitz C, Lecky F, Allgar V & Sheldon T 2019 'Evaluation of the impact of the NICE head injury guidelines on inpatient mortality from traumatic brain injury: an interrupted time series analysis' BMJ Open 9, (6) e028912-e028912, DOI

Wright NMJ, Hearty P & Allgar V 2019 'Prison primary care and non-communicable diseases: a data-linkage survey of prevalence and associated risk factors' BJGP Open 3, (2) bjgpopen19X101643-bjgpopen19X101643, DOI

Barnes-Harris M, Allgar V, Booth S, Currow D, Hart S, Phillips J, Swan F & Johnson MJ 2019 'Battery operated fan and chronic breathlessness: does it help?' BMJ Supportive & Palliative Care, DOI

Allgar VL, Oliver SE, Chen H, Oviasu O, Johnson MJ & Macleod U 2019 'Time intervals from first symptom to diagnosis for head and neck cancers: An analysis of linked patient reports and medical records from the UK' Cancer Epidemiology 59, 37-45, DOI

Howell CA, Markaryan E, Allgar V, Kemppinen A, Khovanov A, Pandya P & Arasaradnam R 2019 'Enterosgel for the treatment of adults with acute diarrhoea in a primary care setting: a randomised controlled trial' BMJ Open Gastroenterology 6, (1) e000287-e000287, DOI

Swan F, Newey A, Bland M, Allgar V, Booth S, Bausewein C, Yorke J & Johnson M 2019 'Airflow relieves chronic breathlessness in people with advanced disease: An exploratory systematic review and meta-analyses' Palliative Medicine 33, (6) 618-633, DOI

Thornton L, Ormsby N, Allgar V & Thomas G 2019 'Can C-Reactive Protein Be Used to Predict Acute Septic Arthritis in the Adult Population?' Southern Medical Journal 112, (2) 108-111, DOI

Baldwin H, Biehal N, Cusworth L, Wade J, Allgar V & Vostanis P 2019 'Disentangling the effect of out-of-home care on child mental health' Child Abuse & Neglect 88, 189-200, DOI

White C, Noble SIR, Watson M, Swan F, Allgar VL, Napier E, Nelson A, McAuley J, Doherty J & Lee B 2019 'Prevalence, symptom burden, and natural history of deep vein thrombosis in people with advanced cancer in specialist palliative care units (HIDDen): a prospective longitudinal observational study' The Lancet Haematology 6, (2) e79-e88, DOI

Cunningham TK, Allgar V, Dargham SR, Kilpatrick E, Sathyapalan T, Maguiness S, Mokhtar Rudin HR, Abdul Ghani NM, Latiff A & Atkin SL 2019 'Association of Vitamin D Metabolites With Embryo Development and Fertilization in Women With and Without PCOS Undergoing Subfertility Treatment' Frontiers in Endocrinology 10, DOI

Hosking J, Pinkney J, Jeffery A, Cominetti O, Da Silva L, Collino S, Kussmann M, Hager J & Martin F 2019 'Insulin Resistance during normal child growth and development is associated with a distinct blood metabolic phenotype (Earlybird 72)' Pediatric Diabetes 20, (7) 832-841, DOI Open access

Carroll CB, Webb D, Stevens KN, Vickery J, Eyre V, Ball S, Wyse R, Webber M, Foggo A & Zajicek J 2019 'Simvastatin as a neuroprotective treatment for Parkinson’s disease (PD STAT): protocol for a double-blind, randomised, placebo-controlled futility study' BMJ Open 9, (10) e029740-e029740, DOI Open access

Bhake R, Russell GM, Kershaw Y, Stevens K, Zaccardi F, Warburton VEC, Linthorst ACE & Lightman SL 2019 'Continuous Free Cortisol Profiles in Healthy Men' The Journal of Clinical Endocrinology & Metabolism 105, (4) e1749-e1761, DOI Open access

Bhake R, Kluckner V, Stassen H, Russell GM, Leendertz J, Stevens K, Linthorst ACE & Lightman SL 2019 'Continuous Free Cortisol Profiles – Circadian Rhythms in Healthy Men' The Journal of Clinical Endocrinology & Metabolism, DOI Open access

Lyndon H, Latour JM, Marsden J, Campbell S, Stevens K & Kent B 2019 'The Holistic Assessment and care Planning in Partnership Intervention Study [HAPPI]: A Protocol for a feasibility, cluster randomised controlled trial' Journal of Advanced Nursing, DOI Open access

Gunn H, Andrade J, Paul L, Miller L, Creanor E, Stevens K, Green C, Ewings P, barton A & Berrow M 2019 'A self-management programme to reduce falls and improve safe mobility in people with secondary progressive MS: the BRiMS feasibility RCT' Health Technology Assessment 23, (27), DOI Open access

Tomlinson DR, Myles M, Stevens KN & Streeter A 2019 'Transmural unipolar electrogram change occurs within 7s at the left atrial posterior wall during pulmonary vein isolation' Pacing and Clinical Electrophysiology, DOI Open access

Mehta N, Stevens K, Smith ME, Williams RJ, Ellis M, Hardman JC & Hopkins C 2019 'National prospective observational study of inpatient management of adults with epistaxis – a National Trainee Research Collaborative delivered investigation' Rhinology journal, DOI Open access

Hanemann CO, Ammoun S, Evans G, Hilton DA, Streeter A & Hayward C 2019 'Phase 0 trial investigating the intra-tumoural concentration and activity of Sorafenib in Neurofibromatosis type 2' Journal of Neurology, Neurosurgery and Psychiatry, DOI Open access

2018

Marincowitz C, Lecky FE, Morris E, Allgar V & Sheldon TA 2018 'Impact of the SIGN head injury guidelines and NHS 4-hour emergency target on hospital admissions for head injury in Scotland: an interrupted times series' BMJ Open 8, (12) e022279-e022279, DOI

Nunn TR, Etsub M, Tilahun T, Gardner ROE, Allgar V, Wainwright AM & Lavy CBD 2018 'Development and validation of a delayed presenting clubfoot score to predict the response to Ponseti casting for children aged 2–10' Strategies in Trauma and Limb Reconstruction 13, (3) 171-177, DOI

Boland JW, Allgar V, Boland EG, Kaasa S, Hjermstad MJ & Johnson MJ 2018 'Predictors and trajectory of performance status in patients with advanced cancer: A secondary data analysis of the international European Palliative Care Cancer Symptom study' Palliative Medicine 33, (2) 206-212, DOI

Allgar VL, Chen H, Richfield E, Currow D, Macleod U & Johnson MJ 2018 'Psychometric Properties of the Needs Assessment Tool—Progressive Disease Cancer in U.K. Primary Care' Journal of Pain and Symptom Management 56, (4) 602-612, DOI

Jones D, Friend C, Dreher A, Allgar V & Macleod U 2018 'The diagnostic test accuracy of rectal examination for prostate cancer diagnosis in symptomatic patients: a systematic review' BMC Family Practice 19, (1), DOI

Biehal N, Baldwin H, Cusworth L, Wade J & Allgar V 2018 'In-home support or out of home care? Thresholds for intervention with abused and neglected children' Children and Youth Services Review 89, 263-271, DOI

Hussain J, Allgar V & Oliver D 2018 'Palliative care triggers in progressive neurodegenerative conditions: An evaluation using a multi-centre retrospective case record review and principal component analysis' Palliative Medicine 32, (4) 716-725, DOI

INTEGRATE 2018 'Epistaxis and mortality' The Journal of Laryngology & Otology 132, (12) 1061-1066, DOI

Wyatt K, LLoyd J, Creanor ES, Green C, Dean SG, Hillsdon M, Abraham C, Tomlinson R, Pearson V, Taylor RS, Ryan E, Streeter A, McHugh C, Hurst A, Price L, Crathorne L, Krägeloh C, Siegert R, Logan S. 2018. Cluster randomised controlled trial and economic and process evaluation to determine the effectiveness and cost-effectiveness of a novel intervention [Healthy Lifestyles Programme (HeLP)] to prevent obesity in school children Doi: – Public Health Research 6 Open access

Lauria M, Persico M, Dordevic N, Cominetti O, Matone A, Hosking J, Jeffery A, Pinkney J, Da Silva L, Priami C, Montoliu I, Martin F-P. 2018. Consensus Clustering of temporal profiles for the identification of metabolic markers of pre-diabetes in childhood (EarlyBird 73) Scientific ReportsDoi: 10.1038/s41598-017-19059-2

Sorrell L, Mcardle N, Becque T, Payne H, Stuart B, Turner S, Wyatt J. Influence of external peer reviewer scores for funding applications on funding board decisions: a retrospective analysis of 1561 reviews. BMJ Open 2018;8:e022547. doi: 10.1136/bmjopen-2018-022547

Attwood D, Stevens K, Jones L, Harris L & Roberts F 2018 'Home visits: A new screening tool for frailty? A retrospective exploratory study' J Family Med Prim Care 7, (5) 1007-1011 Author Site, DOI Open access