The hepatology research group (HRG) is an integral part of the Institute of Translational and Stratified Medicine (ITSMed). We utilise state of the art laboratory facilities based in the John Bull Building, and the world class clinical research strengths of PUPSMD and Plymouth Hospitals NHS Trust (PHNT).
We work in unison with the South West Liver Unit, at Plymouth Hospitals NHS Trust, providing a full range and secondary, tertiary and community Hepatology services to the South West region, including assessment for liver transplantation, TIPS and liver cancer therapy.
The research team run several commercially sponsored clinical trials in hepatitis C therapy, non-alcoholic steatohepatitis (NASH), primary biliary cholangiopathy (PBC), alcoholic liver disease and liver failure amongst others, through the clinical research facilities of The Lind Research Centre at Derriford Hospital.
The broad themes of the hepatology research group are:
- Protection from hepatitis C virus infection – PI Professor Matthew Cramp
- Lipid metabolism and the pathogenesis & treatment of non-alcoholic steatohepatitis – PI Dr David Sheridan
- Alcoholic hepatitis – PI Ashwin Dhanda
- Molecular virology of hepatitis C and other hepatitis viruses – PI Dr Dan Felmlee