Profiles
Dr Victoria Haunton
Honorary Associate Professor
Peninsula Medical School (Faculty of Health)
Biography
Biography
I am an academic geriatrician working at both the University of Plymouth and University Hospital Plymouth NHS Trust. My research expertise is in cerebral haemodynamics, specifically cerebral autoregulation, vasomotor reactivity, and neurovascular coupling, in healthy ageing and neurodegenerative diseases. I have broader research interests and expertise in Parkinson’s disease, blood pressure, frailty, and vascular disease.
I am the lead for the NIHR Clinical Academic Training Programme in Plymouth.
My current grants include awards from the NIHR HTA programme and Parkinson’s UK. I was a previous regional lead for the NIHR Ageing National Specialty group, and have extensive experience as a PI. I sit on several data monitoring and trial steering committees.
Clinically at UHP, I co-lead the Parkinson's service and have a specialist Parkinson's outpatient clinic. I also work on the frailty SDEC unit, and on geriatric medicine wards within the acute hospital.
Qualifications
2004 Bachelor of Medicine (Pass with Distinction), University of Southampton, England, UK
2008 RCP (London) Diploma in Geriatric Medicine
2008 Membership of the Royal College of Physicians (UK)
2010 RCP Speciality Certificate Examination in Geriatric Medicine
2014 Doctor of Medicine (MD), University of Leicester
2019 Fellowship of the Royal College of Physicians (London)
Professional membership
Royal College of Physicians, London
Roles on external bodies
2017-Current Associate Editor, Age and Ageing
2022-Current Chair, British Geriatrics Society Movement Disorders Section (previously trainee rep, research member, and vice-chair).
2023-Current Stakeholder member, UK Parkinson's disease Clinical Studies Group
Key publications
(2022) 'The Cognition and Flow Study (CogFlowS): A Mixed Method Evaluation of a Randomized Feasibility Trial of Cognitive Training in Dementia' Journal of Alzheimer's Disease 87, (3) 1013-1031 , DOI
(2022) 'Cerebrovascular responses to somatomotor stimulation in Parkinson’s disease: A multivariate analysis' Journal of Cerebral Blood Flow & Metabolism 42, (8) 1547-1558 , DOI
(2021) 'Associations of Clinical Frailty with Severity of Limb Threat and Outcomes in Chronic Limb-threatening Ischaemia' Annals of Vascular Surgery 76, 406-416 , DOI
(2021) 'Using complexity–entropy planes to detect Parkinson’s disease from short segments of haemodynamic signals' Physiological Measurement 42, (8) 084002-084002 , DOI
(2021) 'Prevalence of Cognitive Impairment in Individuals with Vascular Surgical Pathology: a Systematic Review and Meta-Analysis' European Journal of Vascular and Endovascular Surgery 61, (4) 664-674 , DOI
Teaching
Teaching
Teaching interests
I am the lead for the NIHR Clinical Academic Training Programme in Plymouth.
Staff serving as external examiners
External Examiner, Clinical Geriatrics MSc, University of Cardiff
Publications
Publications
Key publications
(2022) 'The Cognition and Flow Study (CogFlowS): A Mixed Method Evaluation of a Randomized Feasibility Trial of Cognitive Training in Dementia' Journal of Alzheimer's Disease 87, (3) 1013-1031 , DOI
(2022) 'Cerebrovascular responses to somatomotor stimulation in Parkinson’s disease: A multivariate analysis' Journal of Cerebral Blood Flow & Metabolism 42, (8) 1547-1558 , DOI
(2021) 'Associations of Clinical Frailty with Severity of Limb Threat and Outcomes in Chronic Limb-threatening Ischaemia' Annals of Vascular Surgery 76, 406-416 , DOI
(2021) 'Using complexity–entropy planes to detect Parkinson’s disease from short segments of haemodynamic signals' Physiological Measurement 42, (8) 084002-084002 , DOI
(2021) 'Prevalence of Cognitive Impairment in Individuals with Vascular Surgical Pathology: a Systematic Review and Meta-Analysis' European Journal of Vascular and Endovascular Surgery 61, (4) 664-674 , DOI
Key publications are highlighted
Journals
Articles
(2023) 'Detection of Blood CO2 Influences on Cerebral Hemodynamics Using Transfer Entropy' Entropy 26, (1) 23-23 , DOI
(2023) 'Clinimetrics of performance-based functional outcome measures for vascular amputees: A systematic review' Annals of Physical and Rehabilitation Medicine 66, (6) 101756-101756 , DOI
(2023) 'Relationship of the Wound, Ischemia, and Foot Infection Stage With Frailty, Disability, and Quality of Life at Baseline, and 1-year Outcomes in All-comers With Chronic Limb-threatening Ischemia' Journal of Vascular Surgery 77, (6) e81-e82 , DOI
(2023) 'Cognitive testing following transient ischaemic attack: A systematic review of clinical assessment tools' Cogent Psychology 10, (1) , DOI
(2022) 'Directional sensitivity of dynamic cerebral autoregulation during spontaneous fluctuations in arterial blood pressure at rest' Journal of Cerebral Blood Flow & Metabolism 43, (4) 552-564 , DOI
(2022) 'Antihypertensives in dementia: Good or bad for the brain?' Journal of Cerebral Blood Flow & Metabolism , DOI Open access
(2022) 'Dynamics of the cerebral autoregulatory response to paced hyperventilation assessed using subcomponent and time-varying analyses' Journal of Applied Physiology 133, (2) 311-319 , DOI
(2022) 'The Cognition and Flow Study (CogFlowS): A Mixed Method Evaluation of a Randomized Feasibility Trial of Cognitive Training in Dementia' Journal of Alzheimer's Disease 87, (3) 1013-1031 , DOI
(2022) 'The role of the autonomic nervous system in cerebral blood flow regulation in dementia: A review' Autonomic Neuroscience 240, 102985-102985 , DOI
(2022) 'Cerebrovascular responses to somatomotor stimulation in Parkinson’s disease: A multivariate analysis' Journal of Cerebral Blood Flow & Metabolism 42, (8) 1547-1558 , DOI
(2022) 'Measuring physical performance in the vascular amputee population: A systematic review' Physiotherapy 114, e188-e189 , DOI
(2022) 'Driving and Parkinson’s Disease: A Survey of the Patient’s Perspective' Journal of Parkinson's Disease 12, (1) 465-471 , DOI
(2021) 'The Interaction of Dynamic Cerebral Autoregulation and Neurovascular
Coupling in Cognitive Impairment' Current Alzheimer Research 18, (14) 1067-1076 , DOI
(2021) 'Investigating the association between depression and cerebral haemodynamics—A systematic review and meta-analysis' Journal of Affective Disorders 299, 144-158 , DOI
(2021) 'Extremes of cerebral blood flow during hypercapnic squat‐stand maneuvers' Physiological Reports 9, (19) , DOI
(2021) 'Qualitative Analysis of the Cognition and Flow (CoGFlowS) Study: An Individualized Approach to Cognitive Training for Dementia Is Needed' Journal of Alzheimer's Disease 83, (1) 209-225 , DOI
(2021) 'Using complexity–entropy planes to detect Parkinson’s disease from short segments of haemodynamic signals' Physiological Measurement 42, (8) 084002-084002 , DOI
(2021) 'Cerebral blood flow response rate to task-activation using a novel method can discriminate cognitive impairment from healthy aging' Physiological Measurement 42, (7) 074006-074006 , DOI
(2021) 'Age-related differences in cerebrovascular responses to cognitive stimulation using a novel method' Aging, Neuropsychology, and Cognition 29, (6) 929-942 , DOI
(2021) 'Investigating the association between depressive disorders and cerebral haemodynamics' BJPsych Open 7, (S1) S243-S244 , DOI
(2021) 'Associations of Clinical Frailty with Severity of Limb Threat and Outcomes in Chronic Limb-threatening Ischaemia' Annals of Vascular Surgery 76, 406-416 , DOI
(2021) 'The Cognition and Flow Study: A Feasibility Randomized Controlled Trial of the Effects of Cognitive Training on Cerebral Blood Flow' Journal of Alzheimer's Disease 80, (4) 1567-1581 , DOI
(2021) 'Cerebral critical closing pressure and resistance-area product: the influence of dynamic cerebral autoregulation, age and sex' Journal of Cerebral Blood Flow & Metabolism 41, (9) 2456-2469 , DOI
(2021) 'Prevalence of Cognitive Impairment in Individuals with Vascular Surgical Pathology: a Systematic Review and Meta-Analysis' European Journal of Vascular and Endovascular Surgery 61, (4) 664-674 , DOI
(2021) 'Age and frailty are independently associated with increased COVID-19 mortality and increased care needs in survivors: results of an international multi-centre study' Age and Ageing 50, (3) 617-630 , DOI
(2021) 'Determinants of cerebral blood flow velocity change during squat-stand maneuvers' American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 320, (4) R452-R466 , DOI
(2021) 'Vascular and haemodynamic issues of brain ageing' Pflügers Archiv - European Journal of Physiology 473, (5) 735-751 , DOI
(2021) 'There is no need to reinvent the wheel in assessment of ambulatory function in chronic limb threatening ischemia' Journal of Vascular Surgery 73, (1) 350-351 , DOI
(2020) 'Increasing Blood Pressure Variability Predicts Poor Functional Outcome Following Acute Stroke' Journal of Stroke and Cerebrovascular Diseases 30, (1) 105466-105466 , DOI
(2020) 'The effect of head positioning on cerebral hemodynamics: Experiences in mild ischemic stroke' Journal of the Neurological Sciences 419, 117201-117201 , DOI
(2020) 'Cerebral hemodynamics in stroke thrombolysis (CHiST) study' PLOS ONE 15, (9) e0238620-e0238620 , DOI
(2020) 'Neuroimaging Outcomes in Studies of Cognitive Training in Mild Cognitive Impairment and Early Alzheimer’s Disease: A Systematic Review' Current Alzheimer Research 17, (5) 472-486 , DOI
(2020) 'Does depth of squat‐stand maneuver affect estimates of dynamic cerebral autoregulation?' Physiological Reports 8, (16) , DOI
(2020) 'Driving in Parkinson’s disease: a retrospective study of driving and mobility assessments' Age and Ageing 49, (6) 1097-1101 , DOI
(2020) 'An objective method to identify non-responders in neurovascular coupling testing' Journal of Neuroscience Methods 341, 108779-108779 , DOI
(2020) 'Chasing the evidence: the influence of data segmentation on estimates of dynamic cerebral autoregulation' Physiological Measurement 41, (3) 035006-035006 , DOI
(2019) 'Addenbrooke’s Cognitive Examination III (ACE-III) and mini-ACE for the detection of dementia and mild cognitive impairment' Cochrane Database of Systematic Reviews 2019, (12) Publisher Site , DOI
(2019) 'Frailty and Sarcopenia in Vascular Surgery Patients: A Systematic Review and Meta-analysis of Patient Factors and Outcomes' European Journal of Vascular and Endovascular Surgery 58, (6) e722-e722 , DOI
(2019) 'Can we assess dynamic cerebral autoregulation in stroke patients with high rates of cardiac ectopicity?' Medical & Biological Engineering & Computing 57, (12) 2731-2739 , DOI
(2019) 'Frailty Factors and Outcomes in Vascular Surgery Patients' Annals of Surgery 272, (2) 266-276 , DOI
(2019) 'Can we use short recordings for assessment of dynamic cerebral autoregulation? A sensitivity analysis study in acute ischaemic stroke and healthy subjects' Physiological Measurement 40, (8) 085002-085002 , DOI
(2019) 'Leg ischaemia management collaboration (LIMb): study protocol for a prospective cohort study at a single UK centre' BMJ Open 9, (9) e031257-e031257 , DOI
(2019) 'Assessment of cerebral autoregulation in stroke: A systematic review and meta-analysis of studies at rest' Journal of Cerebral Blood Flow & Metabolism 39, (11) 2105-2116 , DOI
(2019) 'Alternative representation of neural activation in multivariate models of neurovascular coupling in humans' Journal of Neurophysiology 122, (2) 833-843 , DOI
(2019) 'Determining differences between critical closing pressure and resistance-area product: responses of the healthy young and old to hypocapnia' Pflügers Archiv - European Journal of Physiology 471, (8) 1117-1126 , DOI
(2019) 'Effects of brain training on brain blood flow (The Cognition and Flow Study—CogFlowS): protocol for a feasibility randomised controlled trial of cognitive training in dementia' BMJ Open 9, (5) e027817-e027817 , DOI
(2019) 'Increased blood pressure variability following acute stroke is associated with poor long-term outcomes' Blood Pressure Monitoring 24, (2) 67-73 , DOI
(2019) 'Addenbrooke’s Cognitive Examination III (ACE-III) and mini-ACE for the detection of dementia and mild cognitive impairment' Cochrane Database of Systematic Reviews , DOI
(2019) 'Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial' The Lancet 393, (10174) 877-888 , DOI
(2018) 'Inter-subject analysis of transfer function coherence in studies of dynamic cerebral autoregulation' Physiological Measurement 39, (12) 125006-125006 , DOI
(2018) 'Dynamic cerebral autoregulation measurement using rapid changes in head positioning: experiences in acute ischemic stroke and healthy control populations' American Journal of Physiology-Heart and Circulatory Physiology 316, (3) H673-H683 , DOI
(2018) 'The Effects of Healthy Ageing on Cerebral Blood Flow Responses to Cognitive Testing' Current Aging Science 11, (4) 226-235 , DOI
(2018) 'NIHSS cut point for predicting outcome in supra- vs infratentorial acute ischemic stroke' Neurology 91, (18) Publisher Site , DOI
(2018) 'The Assessment of Cerebrovascular Response to a Language Task from the Addenbrooke’s Cognitive Examination in Cognitive Impairment: A Feasibility Functional Transcranial Doppler Ultrasonography Study' Journal of Alzheimer's Disease Reports 2, (1) 153-164 , DOI
(2018) 'How many squat–stand manoeuvres to assess dynamic cerebral autoregulation?' European Journal of Applied Physiology 118, (11) 2377-2384 , DOI
(2018) 'Directional sensitivity of dynamic cerebral autoregulation in squat-stand maneuvers' American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 315, (4) R730-R740 , DOI
(2018) 'Neurovascular coupling response to cognitive examination in healthy controls: a multivariate analysis' Physiological Reports 6, (14) e13803-e13803 , DOI
(2018) 'Does gradual change in head positioning affect cerebrovascular physiology?' Physiological Reports 6, (3) e13603-e13603 , DOI
(2017) 'The assessment of neurovascular coupling with the Addenbrooke’s Cognitive Examination: a functional transcranial Doppler ultrasonographic study' Journal of Neurophysiology 119, (3) 1084-1094 , DOI
(2017) 'Cerebral autoregulation in cardiopulmonary bypass surgery: a systematic review' Interactive CardioVascular and Thoracic Surgery 26, (3) 494-503 , DOI
(2017) 'The cerebrocardiovascular response to periodic squat-stand maneuvers in healthy subjects: a time-domain analysis' American Journal of Physiology-Heart and Circulatory Physiology 313, (6) H1240-H1248 , DOI
(2017) 'Reproducibility of task activation using the Addenbrooke’s cognitive examination in healthy controls: A functional Transcranial Doppler ultrasonography study' Journal of Neuroscience Methods 291, 131-140 , DOI
(2017) 'Cerebral Hemodynamics in Mild Cognitive Impairment: A Systematic Review' Journal of Alzheimer's Disease 59, (1) 369-385 , DOI
(2017) 'Random squat/stand maneuvers: a novel approach for assessment of dynamic cerebral autoregulation?' Journal of Applied Physiology 123, (3) 558-566 , DOI
(2017) 'Transcranial Doppler ultrasonography in the assessment of neurovascular coupling responses to cognitive examination in healthy controls: A feasibility study' Journal of Neuroscience Methods 284, 57-62 , DOI
(2017) 'Intracerebral hemorrhage location and outcome among INTERACT2 participants' Neurology 88, (15) 1408-1414 Publisher Site , DOI
(2017) 'Is cerebral vasomotor reactivity impaired in Parkinson disease?' Clinical Autonomic Research 27, (2) 107-111 , DOI
(2016) 'Cerebral blood flow autoregulation in ischemic heart failure' American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 312, (1) R108-R113 , DOI
(2016) 'The Leicester cerebral haemodynamics database: normative values and the influence of age and sex' Physiological Measurement 37, (9) 1485-1498 , DOI
(2016) 'Prognostic Significance of Hyponatremia in Acute Intracerebral Hemorrhage: Pooled Analysis of the Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial Studies*' Critical Care Medicine 44, (7) 1388-1394 Publisher Site , DOI
(2016) 'Is dynamic cerebral autoregulation measurement using transcranial Doppler ultrasound reproducible in the presence of high concentration oxygen and carbon dioxide?' Physiological Measurement 37, (5) 673-682 , DOI
(2016) 'Statistical criteria for estimation of the cerebral autoregulation index (ARI) at rest' Physiological Measurement 37, (5) 661-672 , DOI
(2016) 'Estimated GFR and the Effect of Intensive Blood Pressure Lowering After Acute Intracerebral Hemorrhage' American Journal of Kidney Diseases 68, (1) 94-102 , DOI
(2016) 'Low Ambient Temperature and Intracerebral Hemorrhage: The INTERACT2 Study' PLOS ONE 11, (2) e0149040-e0149040 Publisher Site , DOI
(2015) 'Determinants and Prognostic Significance of Hematoma Sedimentation Levels in Acute Intracerebral Hemorrhage' Cerebrovascular Diseases 41, (1-2) 80-86 Publisher Site , DOI
(2015) 'Optimal achieved blood pressure in acute intracerebral hemorrhage' Neurology 84, (5) 464-471 Publisher Site , DOI
(2015) 'Higher mortality in patients with right hemispheric intracerebral haemorrhage: INTERACT1 and 2' Journal of Neurology, Neurosurgery & Psychiatry 86, (12) 1319-1323 Publisher Site , DOI
(2015) 'Off-Hour Admission and Outcomes in Patients with Acute Intracerebral Hemorrhage in the INTERACT2 Trial' Cerebrovascular Diseases 40, (3-4) 114-120 Publisher Site , DOI
(2014) 'Interventions for improving modifiable risk factor control in the secondary prevention of stroke' Cochrane Database of Systematic Reviews , DOI
(2014) 'Focus on: transient ischaemic attack' British Journal of Neuroscience Nursing 10, (Sup2) 6-11 , DOI
(2014) 'A review of current guidance and evidence on driving in older age' CME Journal Geriatric Medicine 15, (2) 43-52
(2013) 'Rapid Blood-Pressure Lowering in Patients with Acute Intracerebral Hemorrhage' New England Journal of Medicine 368, (25) 2355-2365 Publisher Site , DOI
(2013) 'A systematic review of cerebral hemodynamic responses to neural activation following stroke' Journal of Neurology 260, (11) 2715-2721 , DOI
(2012) 'The face arm speech test: does it encourage rapid recognition of important stroke warning symptoms?' Emergency Medicine Journal 30, (6) 467-471 , DOI
(2011) 'Impulse control disorders and Parkinson's disease: A clinical review' CME Journal Geriatric Medicine 13, (1) 21-24
Chapters
Brazier D, Scourfield L, Lyell V, Haunton V, Henderson E. Falls and Bone health in Parkinson’s in Parkinson’s Disease: A Multidisciplinary Guide to Management, 1st Edition. Elsevier. 2021 ISBN: 9780702082610
Haunton V, Sett A, Mistri AK, Fotherby M. Stroke in Diagnosis and Treatment in Internal Medicine. OUP. 2018 ISBN: 9780199568741
Haunton V, Robinson T. Modern management of TIA and stroke in Oxford Textbook of Vascular Surgery. OUP. 2016 ISBN: 9780199658220
Haunton V, Lo N. Parkinson’s plus syndromes. Oxford Desk Reference: Geriatric Medicine. OUP. 2012. ISBN: 9780199592340
(2016) 'Modern medical management of TIA and stroke' Oxford Textbook of Vascular Surgery Oxford University Press 388-398 , DOI
Presentations and posters
'Associations and One-year Trends of Frailty, Cognition, Disability, and Quality of Life in Individuals with Chronic Limb-threatening Ischemia' , DOI
'O058 Association and one-year trends of frailty, cognition, disability, and quality of life in individuals with chronic limb-threatening ischaemia' , DOI
'407 QUALITATIVE ASSESSMENT OF COGNITIVE TRAINING FOR PEOPLE LIVING WITH DEMENTIA: AN INDIVIDUALISED APPROACH IS NEEDED AUTHORS' , DOI
'100 Prevalence of Cognitive Impairment in Vascular Surgery Patients: Preliminary Results of A Systematic Review and Meta-Analysis' , DOI