Professor David Bristow
Profiles

Professor David Bristow

Head of Peninsula School of Medicine

Peninsula Medical School (Plymouth University Peninsula Schools of Medicine and Dentistry)

Role

As Head of Peninsula School of Medicine, I provide strategic leadership to the undergraduate and postgraduate medical programmes to ensure the delivery of the highest quality of educational provision.  Throughout my career in higher education I have been interested in the processes of teaching and learning, and am especially motivated to develop  evidence-based curricula  that produce excellent doctors and scientists. I am committed to support students and staff to achieve their full potential.  My research is investigating  the reliability and validity of medical student selection ,   faculty and staffing structure and professional identity ,  the best ways of teaching safe and effective prescribing,  and the effectiveness of integrated medical sciences curricula.

Key publications are highlighted

Journals
Articles
Lambe P, Kay E & Bristow D 2016 'Exploring uses of the UK Clinical Aptitude Test-situational judgement test in a dental student selection process' European Journal of Dental Education , DOI PEARL
Lambe P, Waters C & Bristow D 2013 'Do differentials in the support and advice available at UK schools and colleges influence candidate performance in the medical school admissions interview? A survey of direct school leaver applicants to a UK medical school' Med Teach 35, (9) 731-739 Author Site , DOI
Lambe P, Waters C & Bristow D 2012 'The UK Clinical Aptitude Test: is it a fair test for selecting medical students?' Med Teach 34, (8) e557-e565 Author Site , DOI
Lambe P & Bristow D 2011 'Predicting medical student performance from attributes at entry: a latent class analysis' MEDICAL EDUCATION 45, (3) 308-316 Author Site , DOI
Harding S, Britten N & Bristow D 2010 'The performance of junior doctors in applying clinical pharmacology knowledge and prescribing skills to standardized clinical cases' Br J Clin Pharmacol 69, (6) 598-606 Author Site , DOI
Lambe P & Bristow D 2010 'What are the most important non-academic attributes of good doctors? A Delphi survey of clinicians' MEDICAL TEACHER 32, (8) E347-E354 Author Site , DOI
Hudson JN & Bristow DR 2006 'Formative assessment can be fun as well as educational' Advances in Physiology Education 30, (1) 33-37
Hudson JN & Bristow DR 2006 'Formative assessment can be fun as well as educational' ADVANCES IN PHYSIOLOGY EDUCATION 30, (1) 33-37 Author Site , DOI
Zamani MR, Leeson AH, Nash J & Bristow DR 2002 'Histamine induces the phosphorylation of a 58 kDa protein in GT1-7 neuronal cells' NEUROSCIENCE RESEARCH COMMUNICATIONS 31, (1) 11-18 Author Site , DOI
Leeson AH, Zamani MR & Bristow DR 1999 'Acute histamine exposure induced the phosphorylation of a 58 KDa protein in mouse hypothalamic GT1-7 neuronal cells' BRITISH JOURNAL OF PHARMACOLOGY 127, U32-U32 Author Site
Savidge JR, Sturgess NC, Bristow DR & Lock EA 1999 'Characterisation of kainate receptor mediated whole-cell currents in rat cultured cerebellar granule cells' Neuropharmacology 38, (3) 375-382 Author Site
Savidge JR & Bristow DR 1998 'Ca2+ permeability and joro spider toxin sensitivity of AMPA and kainate receptors on cerebellar granule cells' Eur J Pharmacol 351, (1) 131-138 Author Site
Savidge JR, Sturgess NC, Bristow DR & Lock EA 1998 'Discrimination of whole-cell currents mediated by AMPA- and kainate-type glutamate receptors in rat cultured cerebellar granule cells' BRITISH JOURNAL OF PHARMACOLOGY 124, U70-U70 Author Site
Johnston JD, Price SA & Bristow DR 1998 'Flunitrazepam rapidly reduces GABA(A) receptor subunit protein expression via a protein kinase C-dependent mechanism' Br J Pharmacol 124, (7) 1338-1340 Author Site , DOI
Brown MJ, Wood MD, Coldwell MC & Bristow DR 1998 'Gamma-aminobutyric acidA receptor function is desensitised in rat cultured cerebellar granule cells following chronic flunitrazepam treatment' J Neurochem 71, (3) 1232-1240 Author Site
Wood AM & Bristow DR 1998 'N-methyl-D-aspartate receptor desensitisation is neuroprotective by inhibiting glutamate-induced apoptotic-like death' J Neurochem 70, (2) 677-687 Author Site
Johnston JD & Bristow DR 1998 'Regulation of GABAA receptor α1 protein is a sensitive indicator of benzodiazepine agonist efficacy' European Journal of Pharmacology 348, (2-3) 321-324 , DOI
Staton PC & Bristow DR 1998 'Role of group III metabotropic glutamate receptors in excitotoxin-induced cerebellar granule cell death' J Neurochem 71, (3) 1280-1288 Author Site
Brown MJ, Wood MD, Coldwell MC & Bristow DR 1998 'γ-Aminobutyric AcidA Receptor Function Is Desensitised in Rat Cultured Cerebellar Granule Cells Following Chronic Flunitrazepam Treatment' Journal of Neurochemistry 71, (3) 1232-1240 , DOI
Savidge JR & Bristow DR 1997 'Distribution of Ca2+-permeable AMPA receptors among cultured rat cerebellar granule cells' NeuroReport 8, (8) 1877-1882 , DOI
Savidge JR, Bleakman D & Bristow DR 1997 'Identification of kainate receptor-mediated intracellular calcium increases in cultured rat cerebellar granule cells' J Neurochem 69, (4) 1763-1766 Author Site
Brown MJ, Wood MD, Coldwell MC & Bristow DR 1997 'Measurement of GABAA receptor function in rat cultured cerebellar granule cells by the Cytosensor microphysiometer' Br J Pharmacol 121, (1) 71-76 Author Site , DOI
Wood AM, Tiwari P & Bristow DR 1997 'Media composition modulates excitatory amino acid-induced death of rat cerebellar granule cells' Hum Exp Toxicol 16, (7) 350-355 Author Site , DOI
Savidge JR & Bristow DR 1997 'Routes of NMDA- and K+-stimulated calcium entry in rat cerebellar granule cells' Neuroscience Letters 229, (2) 109-112 , DOI
Staton PC & Bristow DR 1997 'The Dietary Excitotoxins β-N-Methylamino-l-Alanine and β-N-Oxalylamino-l-Alanine Induce Necrotic- and Apoptotic-Like Death of Rat Cerebellar Granule Cells' Journal of Neurochemistry 69, (4) 1508-1518 , DOI
Savidge JR & Bristow DR 1996 'Agonist regulation of N-methyl-D-aspartate (NMDA)-induced intracellular calcium elevations in rat cerebellar granule cells' BRITISH JOURNAL OF PHARMACOLOGY 119, P251-P251 Author Site
Staton PC & Bristow DR 1996 'Mechanisms of beta-methylamino-L-alanine (BMAA)- and beta-oxalylamino-L-alanine (BOAA)-induced death in rat cerebellar granule cells' BRITISH JOURNAL OF PHARMACOLOGY 117, P189-P189 Author Site
Brown MJ & Bristow DR 1996 'Molecular mechanisms of benzodiazepine-induced down-regulation of GABAA receptor α1 subunit protein in rat cerebellar granule cells' British Journal of Pharmacology 118, (5) 1103-1110 , DOI
Platt KP, Zwartjes RE & Bristow DR 1996 'The effect of GABA stimulation on GABAA receptor subunit protein and mRNA expression in rat cultured cerebellar granule cells' Br J Pharmacol 119, (7) 1393-1400 Author Site
Zamani MR & Bristow DR 1996 'The histamine H1 receptor in GT1-7 neuronal cells is regulated by calcium influx and KN-62, a putative inhibitor of calcium/calmodulin protein kinase II' Br J Pharmacol 118, (5) 1119-1126 Author Site
Spencer DC & Bristow DR 1995 'Effect of chronic agonist treatment on the expression of the GABAA receptor in rat cerebellar granule cells' Behavioural Pharmacology 6, (SUPPLEMENT 1) 113-113 , DOI
Platt KP & Bristow DR 1995 'Excitatory amino acid-induced neuronal cell death in rat cerebellar granule cell cultures' Biochem Soc Trans 23, (4) Author Site
Wood AM & Bristow DR 1995 'Media composition modulates glutamate-induced cell death in rat cerebellar granule cells' Biochem Soc Trans 23, (4) Author Site
Zamani MR, Dupere JR & Bristow DR 1995 'Receptor-mediated desensitisation of histamine H1 receptor-stimulated inositol phosphate production and calcium mobilisation in GT1-7 neuronal cells is independent of protein kinase C' J Neurochem 65, (1) 160-169 Author Site
SPENCER DC & BRISTOW DR 1995 'THE EFFECT OF CHRONIC AGONIST STIMULATION ON THE EXPRESSION OF GABA(A) RECEPTORS IN RAT CEREBELLAR GRANULE CELLS' BRITISH JOURNAL OF PHARMACOLOGY 114, P297-P297 Author Site
Brown MJ & Bristow DR 1995 'The effect of chronic benzodiazepine on GABAA receptor subunit protein expression in rat cerebellar granule cells' Behavioural Pharmacology 6, (SUPPLEMENT 1) 104-104 , DOI
BROWN MJ & BRISTOW DR 1995 'THE EFFECT OF CHRONIC BENZODIAZEPINE TREATMENT ON GABA(A) RECEPTOR SUBUNIT PROTEIN EXPRESSION IN RAT CEREBELLAR GRANULE CELLS' BRITISH JOURNAL OF PHARMACOLOGY 114, P298-P298 Author Site
Zamani MR, Dupere JR & Bristow DR 1994 'An immortalised murine hypothalamic neuronal cell, GT1-7, expresses functional histamine H1 receptors' Neurosci Lett 178, (1) 159-162 Author Site
Zamani R & Bristow DR 1993 'Desensitisation of histamine H1 receptor-mediated calcium mobilisation in HeLa cells: the role of protein kinase C' Biochem Soc Trans 21, (4) Author Site
Bristow DR, Banford PC, Bajusz I, Vedat A & Young JM 1993 'Desensitization of histamine H1 receptor-mediated inositol phosphate accumulation in guinea pig cerebral cortex slices' Br J Pharmacol 110, (1) 269-274 Author Site
Bristow DR & Zamani MR 1993 'Desensitization of histamine H1 receptor-mediated inositol phosphate production in HeLa cells' Br J Pharmacol 109, (2) 353-359 Author Site
Bristow DR & Young JM 1991 'Characteristics of histamine-induced inositol phospholipid hydrolysis in HeLa cells' Agents Actions Suppl 33, 387-392 Author Site
Bristow DR, Arias-Montaño JA & Young JM 1991 'Histamine-induced inositol phosphate accumulation in HeLa cells: lithium sensitivity' British Journal of Pharmacology 104, (3) 677-684 , DOI
Bristow DR & Martin IL 1990 'Biochemical Characterization of an Isolated and Functionally Reconstituted ?-Aminobutyric Acid/Benzodiazepine Receptor' Journal of Neurochemistry 54, (3) 751-761 , DOI
Bristow DR, Moratalla R & Martin IL 1990 'Flunitrazepam increases the affinity of the GABAA receptor in cryostat-cut rat brain sections' European Journal of Pharmacology 184, (2-3) 339-340 , DOI
Bristow DR & Martin IL 1989 'GABA preincubation of rat brain sections increases [3H]GABA binding to the GABAA receptor and compromises the modulatory interactions' European Journal of Pharmacology 173, (1) 65-73 , DOI
Bristow DR & Martin IL 1988 'Light microscopic autoradiographic localisation in rat brain of the binding sites for the GABAA receptor antagonist [3H]SR 95531: Comparison with the [3H]GABAA receptor distribution' European Journal of Pharmacology 148, (2) 283-288 , DOI
Bristow DR, Curtis NR, Suman-Chauhan N, Watling KJ & Williams BJ 1987 'Effects of tachykinins on inositol phospholipid hydrolysis in slices of hamster urinary bladder' British Journal of Pharmacology 90, (1) 211-217 , DOI
Bristow DR & Martin IL 1987 'Solubilisation of the ?-Aminobutyric Acid/Benzodiazepine Receptor from Rat Cerebellum: Optimal Preservation of the Modulatory Responses by Natural Brain Lipids' Journal of Neurochemistry 49, (5) 1386-1393 , DOI
Bristow DR & Martin IL 1987 'Solubilisation of the Benzodiazepine Receptor from Rat Cerebellum by the Detergent n-Octylpentaoxyethylene' Journal of Neurochemistry 48, (5) 1537-1540 , DOI
Watling KJ & Bristow DR 1986 'GABAB Receptor-Mediated Enhancement of Vasoactive Intestinal Peptide-Stimulated Cyclic AMP Production in Slices of Rat Cerebral Cortex' Journal of Neurochemistry 46, (6) 1755-1762 , DOI
Bristow DR, Bowery NG & Woodruff GN 1986 'Light microscopic autoradiographic localisation of [3H]glycine and [3H]strychnine binding sites in rat brain' European Journal of Pharmacology 126, (3) 303-307 , DOI
Conference Papers
Platt KP & Bristow DR 1995 'Excitatory amino acid-induced neuronal cell death in rat cerebellar granule cell cultures' S599-S599
Wood AM & Bristow DR 1995 'Media composition modulates glutamate-induced cell death in rat cerebellar granule cells' S596-S596