- C415, Portland Square, Drake Circus, Plymouth, PL4 8AA
- +44 1752 586754
- david.bristow@plymouth.ac.uk
Profiles
Professor David Bristow
Emeritus Professor
Peninsula Medical School (Faculty of Health)
Biography
Biography
As Head of Peninsula School of Medicine, I provide strategic leadership to the undergraduate and postgraduate medical programmes to ensure the delivery of the highest quality of educational provision. Throughout my career in higher education I have been interested in the processes of teaching and learning, and am especially motivated to develop evidence-based curricula that produce excellent doctors and scientists. I am committed to support students and staff to achieve their full potential. My research is investigating the reliability and validity of medical student selection , faculty and staffing structure and professional identity , the best ways of teaching safe and effective prescribing, and the effectiveness of integrated medical sciences curricula.
Publications
Publications
Key publications
Key publications are highlighted
Journals
Articles
(2016) 'Exploring uses of the UK Clinical Aptitude Test-situational judgement test in a dental student selection process' European Journal of Dental Education , DOI Open access
(2013) 'Do differentials in the support and advice available at UK schools and colleges influence candidate performance in the medical school admissions interview? A survey of direct school leaver applicants to a UK medical school' Med Teach 35, (9) 731-739 , DOI
(2012) 'The UK Clinical Aptitude Test: is it a fair test for selecting medical students?' Med Teach 34, (8) e557-e565 , DOI
(2011) 'Predicting medical student performance from attributes at entry: a latent class analysis' MEDICAL EDUCATION 45, (3) 308-316 , DOI
(2010) 'The performance of junior doctors in applying clinical pharmacology knowledge and prescribing skills to standardized clinical cases' Br J Clin Pharmacol 69, (6) 598-606 , DOI
(2010) 'What are the most important non-academic attributes of good doctors? A Delphi survey of clinicians' MEDICAL TEACHER 32, (8) E347-E354 , DOI
(2006) 'GABAB Receptor-Mediated Enhancement of Vasoactive Intestinal Peptide-Stimulated Cyclic AMP Production in Slices of Rat Cerebral Cortex' Journal of Neurochemistry 46, (6) 1755-1762 , DOI
(2006) 'Formative assessment can be fun as well as educational' ADVANCES IN PHYSIOLOGY EDUCATION 30, (1) 33-37 , DOI
(2006) 'Formative assessment can be fun as well as educational' Advances in Physiology Education 30, (1) 33-37
(2002) 'γ-Aminobutyric AcidA Receptor Function Is Desensitised in Rat Cultured Cerebellar Granule Cells Following Chronic Flunitrazepam Treatment' Journal of Neurochemistry 71, (3) 1232-1240 , DOI
(2002) 'Histamine induces the phosphorylation of a 58 kDa protein in GT1-7 neuronal cells' NEUROSCIENCE RESEARCH COMMUNICATIONS 31, (1) 11-18 , DOI
(1999) 'Acute histamine exposure induced the phosphorylation of a 58 KDa protein in mouse hypothalamic GT1-7 neuronal cells' BRITISH JOURNAL OF PHARMACOLOGY 127, U32-U32
(1999) 'Characterisation of kainate receptor mediated whole-cell currents in rat cultured cerebellar granule cells' Neuropharmacology 38, (3) 375-382 , DOI
(1998) 'Gamma-aminobutyric acidA receptor function is desensitised in rat cultured cerebellar granule cells following chronic flunitrazepam treatment' J Neurochem 71, (3) 1232-1240 , DOI
(1998) 'Role of group III metabotropic glutamate receptors in excitotoxin-induced cerebellar granule cell death' J Neurochem 71, (3) 1280-1288 , DOI
(1998) 'Flunitrazepam rapidly reduces GABA(A) receptor subunit protein expression via a protein kinase C-dependent mechanism' Br J Pharmacol 124, (7) 1338-1340 , DOI
(1998) 'Discrimination of whole-cell currents mediated by AMPA- and kainate-type glutamate receptors in rat cultured cerebellar granule cells' BRITISH JOURNAL OF PHARMACOLOGY 124, U70-U70
(1998) 'Ca2+ permeability and joro spider toxin sensitivity of AMPA and kainate receptors on cerebellar granule cells' Eur J Pharmacol 351, (1) 131-138 , DOI
(1998) 'Regulation of GABA(A) receptor alpha1 protein is a sensitive indicator of benzodiazepine agonist efficacy' Eur J Pharmacol 348, (2-3) 321-324 , DOI
(1998) 'N-methyl-D-aspartate receptor desensitisation is neuroprotective by inhibiting glutamate-induced apoptotic-like death' J Neurochem 70, (2) 677-687 , DOI
(1997) 'Identification of kainate receptor-mediated intracellular calcium increases in cultured rat cerebellar granule cells' J Neurochem 69, (4) 1763-1766 , DOI
(1997) 'The dietary excitotoxins beta-N-methylamino-L-alanine and beta-N-oxalylamino-L-alanine induce necrotic- and apoptotic-like death of rat cerebellar granule cells' J Neurochem 69, (4) 1508-1518 , DOI
(1997) 'Media composition modulates excitatory amino acid-induced death of rat cerebellar granule cells' Hum Exp Toxicol 16, (7) 350-355 , DOI
(1997) 'Routes of NMDA- and K(+)-stimulated calcium entry in rat cerebellar granule cells' Neurosci Lett 229, (2) 109-112 , DOI
(1997) 'Distribution of Ca(2+)-permeable AMPA receptors among cultured rat cerebellar granule cells' Neuroreport 8, (8) 1877-1882 , DOI
(1997) 'Measurement of GABAA receptor function in rat cultured cerebellar granule cells by the Cytosensor microphysiometer' Br J Pharmacol 121, (1) 71-76 , DOI
(1996) 'The effect of GABA stimulation on GABAA receptor subunit protein and mRNA expression in rat cultured cerebellar granule cells' Br J Pharmacol 119, (7) 1393-1400 , DOI
(1996) 'Agonist regulation of N-methyl-D-aspartate (NMDA)-induced intracellular calcium elevations in rat cerebellar granule cells' BRITISH JOURNAL OF PHARMACOLOGY 119, P251-P251
(1996) 'Molecular mechanisms of benzodiazepine-induced down-regulation of GABAA receptor alpha 1 subunit protein in rat cerebellar granule cells' Br J Pharmacol 118, (5) 1103-1110 , DOI
(1996) 'The histamine H1 receptor in GT1-7 neuronal cells is regulated by calcium influx and KN-62, a putative inhibitor of calcium/calmodulin protein kinase II' Br J Pharmacol 118, (5) 1119-1126 , DOI
(1996) 'Mechanisms of beta-methylamino-L-alanine (BMAA)- and beta-oxalylamino-L-alanine (BOAA)-induced death in rat cerebellar granule cells' BRITISH JOURNAL OF PHARMACOLOGY 117, P189-P189
(1995) 'Excitatory amino acid-induced neuronal cell death in rat cerebellar granule cell cultures' Biochem Soc Trans 23, (4) , DOI
(1995) 'Media composition modulates glutamate-induced cell death in rat cerebellar granule cells' Biochem Soc Trans 23, (4) , DOI
(1995) 'Receptor-mediated desensitisation of histamine H1 receptor-stimulated inositol phosphate production and calcium mobilisation in GT1-7 neuronal cells is independent of protein kinase C' J Neurochem 65, (1) 160-169 , DOI
(1995) 'Effect of chronic agonist treatment on the expression of the GABA(A) receptor in rat cerebellar granule cells' BEHAVIOURAL PHARMACOLOGY 6, 113-114 , DOI
(1995) 'The effect of chronic benzodiazepine on GABA(A) receptor subunit protein expression in rat cerebellar granule cells' BEHAVIOURAL PHARMACOLOGY 6, 104-105 , DOI
(1995) 'THE EFFECT OF CHRONIC AGONIST STIMULATION ON THE EXPRESSION OF GABA(A) RECEPTORS IN RAT CEREBELLAR GRANULE CELLS' BRITISH JOURNAL OF PHARMACOLOGY 114, P297-P297
(1995) 'THE EFFECT OF CHRONIC BENZODIAZEPINE TREATMENT ON GABA(A) RECEPTOR SUBUNIT PROTEIN EXPRESSION IN RAT CEREBELLAR GRANULE CELLS' BRITISH JOURNAL OF PHARMACOLOGY 114, P298-P298
(1994) 'An immortalised murine hypothalamic neuronal cell, GT1-7, expresses functional histamine H1 receptors' Neurosci Lett 178, (1) 159-162 , DOI
(1993) 'Desensitisation of histamine H1 receptor-mediated calcium mobilisation in HeLa cells: the role of protein kinase C' Biochem Soc Trans 21, (4) , DOI
(1993) 'Desensitization of histamine H1 receptor-mediated inositol phosphate accumulation in guinea pig cerebral cortex slices' Br J Pharmacol 110, (1) 269-274 , DOI
(1993) 'Desensitization of histamine H1 receptor-mediated inositol phosphate production in HeLa cells' Br J Pharmacol 109, (2) 353-359 , DOI
(1991) 'Histamine-induced inositol phosphate accumulation in HeLa cells: lithium sensitivity' British Journal of Pharmacology 104, (3) 677-684 , DOI
(1991) 'Characteristics of Histamine-Induced Inositol Phospholipid Hydrolysis in Hela Cells' 387-392 , DOI
(1990) 'Flunitrazepam increases the affinity of the GABAA receptor in cryostat-cut rat brain sections' European Journal of Pharmacology 184, (2-3) 339-340 , DOI
(1990) 'Biochemical Characterization of an Isolated and Functionally Reconstituted ?-Aminobutyric Acid/Benzodiazepine Receptor' Journal of Neurochemistry 54, (3) 751-761 , DOI
(1989) 'GABA preincubation of rat brain sections increases [3H]GABA binding to the GABAA receptor and compromises the modulatory interactions' European Journal of Pharmacology 173, (1) 65-73 , DOI
(1988) 'Light microscopic autoradiographic localisation in rat brain of the binding sites for the GABAA receptor antagonist [3H]SR 95531: Comparison with the [3H]GABAA receptor distribution' European Journal of Pharmacology 148, (2) 283-288 , DOI
(1987) 'Solubilisation of the ?-Aminobutyric Acid/Benzodiazepine Receptor from Rat Cerebellum: Optimal Preservation of the Modulatory Responses by Natural Brain Lipids' Journal of Neurochemistry 49, (5) 1386-1393 , DOI
(1987) 'Solubilisation of the Benzodiazepine Receptor from Rat Cerebellum by the Detergent n-Octylpentaoxyethylene' Journal of Neurochemistry 48, (5) 1537-1540 , DOI
(1987) 'Effects of tachykinins on inositol phospholipid hydrolysis in slices of hamster urinary bladder' British Journal of Pharmacology 90, (1) 211-217 , DOI
(1986) 'Light microscopic autoradiographic localisation of [3H]glycine and [3H]strychnine binding sites in rat brain' European Journal of Pharmacology 126, (3) 303-307 , DOI