Dr Chiara Boschetti
Profiles

Dr Chiara Boschetti

Lecturer in Biological Sciences

School of Biological and Marine Sciences (Faculty of Science and Engineering)

Role

Lecturer in Biological Sciences

Co-organiser of the School of Biological and Marine Sciences External Seminar Series

Organiser of the Molecular Breakfast and Bioinformatics Club internal series

Previous roles

Senior Research Associate, Department of Chemical Engineering and Biotechnology, University of Cambridge, UK & Head of Biology, Cambridge Infinitus Research Centre, University of Cambridge, UK

Post-Doctoral Research Associate, Department of Chemical Engineering and Biotechnology, University of Cambridge, UK

Research visitor, Department of Life Sciences, Imperial College London, UK

PhD in Animal Biology, Department of Biology, Università degli Studi di Milano, Italy

Professional membership

Fellow of Higher Education Academy

Roles on external bodies

Reviewer for various Journals including Science, PLoS ONE, Biological Journal of the Linnean Society, Comparative Biochemistry and Physiology, Evolution, Genome Biology and Evolution, Hydrobiologia, Gene.

Teaching interests

Main teaching interests: zoology, comparative genomics, evolution, physiology of stress resistance, cell and molecular biology, microscopy.

Research interests

Comparative genomics of stress resistant micro-metazoans (rotifers, tardigrades and nematodes).


Barbosa EGG, A Crisp, S Broadbent, M Carrillo, C Boschetti & A Tunnacliffe (2016). A functional difference between native and horizontally acquired genes in bdelloid rotifers. Gene 590: 186-191. doi: 10.1016/j.gene.2016.06.019.

Eyres I, C Boschetti, A Crisp, D Fontaneto, A Tunnacliffe & TG Barraclough (2015). Horizontal gene transfer in bdelloid rotifers is ancient, ongoing and more frequent in species from desiccating habitats. BMC Biol 13: 90. doi:10.1186/s12915-015-0202-9.

Lu M, C Boschetti & A Tunnacliffe (2015). Long term aggresome accumulation leads to DNA damage, p53-dependent cell cycle arrest, and steric interference in mitosis. J Biol Chem 290: 27986-28000. doi: 10.1074/jbc.M115.676437.

Crisp A, C Boschetti, M Perry, A Tunnacliffe & G Micklem (2015). Expression of multiple horizontally acquired genes is a hallmark of both vertebrate and invertebrate genomes. Gen Biol 16: 50. doi:10.1186/s13059-015-0607-3.

Lu M, N Williamson, C Boschetti, T Ellis, T Yoshimi & A Tunnacliffe (2015). Expression-level dependent perturbation of cell proteostasis and nuclear morphology by aggregation-prone polyglutamine proteins. Biotech Bioeng 112: 1883-1892. doi: 10.1002/bit.25606.

Szydlowski L, C Boschetti, A Crisp, EGG Barbosa, G Micklem & A Tunnacliffe (2015). Multiple horizontally acquired genes encode cellulose-digesting enzymes in the bdelloid rotifer Adineta ricciae. Gene 566: 125-137. doi:10.1016/j.gene.2015.04.007.

Boschetti C, A Crisp, G Micklem, MJ Wise & A Tunnacliffe (2013). Anhydrobiosis: the curious case of the bdelloid rotifer. Cryobiol Cryotechnol 59: 29-34.

Boschetti C, A Carr, A Crisp, I Eyres, Y Wang-Koh, E Lubzens, TG Barraclough, G Micklem & A Tunnacliffe (2012). Biochemical diversification through foreign gene expression in bdelloid rotifers. PLoS Gen 8(11): e1003035.

Eyres I, E Frangedakis, D Fontaneto, EA Herniou, C Boschetti, A Carr, G Micklem, A Tunnacliffe & TG Barraclough (2012). Multiple functionally divergent and conserved copies of alpha tubulin in bdelloid rotifers. BMC Evol Biol 12: 148. doi: 10.1186/1471-2148-12-148.

Tripathi R, C Boschetti, B McGee & A Tunnacliffe (2012). Trafficking of bdelloid rotifer late embryogenesis abundant proteins. J Exp Biol 215: 2786-2794. doi: 10.1242/jeb.071647.

Boschetti C, F Leasi & C Ricci (2011). Developmental stages in diapausing eggs: an investigation across monogonont rotifer species. Hydrobiol 662: 149-155. doi:10.1007/s10750-010-0490-6.

Boschetti C, N Pouchkina-Stantcheva, P Hoffmann & A Tunnacliffe (2011). Foreign genes and novel hydrophilic protein genes participate in the desiccation response of the bdelloid rotifer Adineta ricciae. J Exp Biol 214: 59-68. doi: 10.1242/jeb.050328.

Wang X, C Boschetti, MJ Ruedas-Rama, A Tunnacliffe & EAH Hall (2010). Ratiometric pH-dot ANSors. Analyst 135: 1585-1591. doi: 10.1039/b922751b.

Fontaneto D, C Boschetti & C Ricci (2008). Cryptic diversification in ancient asexuals: evidence from the bdelloid rotifer Philodina flaviceps. J Evol Biol 21: 580-587. doi: 10.1111/j.1420-9101.2007.01472.x.

Pouchkina-Stantcheva NN, BM McGee, C Boschetti, D Tolleter, S Chakrabortee, AV Popova, F Meersman, D Macherel, DK Hincha & A Tunnacliffe (2007). Functional divergence of former alleles in an ancient asexual invertebrate. Science 318: 268-271. doi: 10.1126/science.1144363.

Fontaneto D, EA Herniou, C Boschetti, M Caprioli, G Melone, C Ricci & TG Barraclough (2007). Independently evolving species in asexual bdelloid rotifers. PLoS Biol 5(4): e87. doi: 10.1371/journal.pbio.0050087.

Chakrabortee S, C Boschetti, LJ Walton, S Sarkar, DC Rubinsztein & A Tunnacliffe (2007). Hydrophilic protein associated with desiccation tolerance exhibits broad protein stabilization function. Proc Natl Acad Sci U S A 104: 18073-18078. doi: 10.1073/pnas.0706964104.

Ricci C, M Caprioli, C Boschetti & N Santo (2005). Macrotrachela quadricornifera featured in a space experiment. Hydrobiol 534: 239-244. doi: 10.1007/s10750-004-1509-7.

Boschetti C, C Ricci, C Sotgia & U Fascio (2005). The development of a bdelloid egg: a contribution after 100 years. Hydrobiol 546: 323-331. doi: 10.1007/1-4020-4408-9_33.

Ricci C & C Boschetti (2003). Bdelloid rotifers as model system to study developmental biology in space. Adv Space Biol Med 9: 25-39.

Key publications are highlighted

Journals
Articles
Nowell R, Almeida P, Wilson C, Smith T, Fontaneto D, Crisp A, Micklem G, Tunnacliffe A, Boschetti C & Barraclough T 2018 'Comparative genomics of bdelloid rotifers: insights from desiccating and non-desiccating species' PLoS Biology , DOI PEARL
Barbosa EGG, Crisp A, Broadbent SE, Carrillo M, Boschetti C & Tunnacliffe A 2016 'A functional difference between native and horizontally acquired genes in bdelloid rotifers' Gene 590, (1) 186-191 , DOI
Eyres I, Boschetti C, Crisp A, Smith TP, Fontaneto D, Tunnacliffe A & Barraclough TG 2015 'Horizontal gene transfer in bdelloid rotifers is ancient, ongoing and more frequent in species from desiccating habitats' BMC Biology 13, (1) , DOI PEARL
Lu M, Boschetti C & Tunnacliffe A 2015 'Long Term Aggresome Accumulation Leads to DNA Damage, p53-dependent Cell Cycle Arrest, and Steric Interference in Mitosis' Journal of Biological Chemistry 290, (46) 27986-28000 , DOI PEARL
Szydlowski L, Boschetti C, Crisp A, Barbosa EGG & Tunnacliffe A 2015 'Multiple horizontally acquired genes from fungal and prokaryotic donors encode cellulolytic enzymes in the bdelloid rotifer Adineta ricciae' Gene 566, (2) 125-137 , DOI
Lu M, Williamson N, Boschetti C, Ellis T, Yoshimi T & Tunnacliffe A 2015 'Expression-level dependent perturbation of cell proteostasis and nuclear morphology by aggregation-prone polyglutamine proteins' Biotechnology and Bioengineering 112, (9) 1883-1892 , DOI
Crisp A, Boschetti C, Perry M, Tunnacliffe A & Micklem G 2015 'Expression of multiple horizontally acquired genes is a hallmark of both vertebrate and invertebrate genomes' Genome Biology 16, (1) , DOI PEARL
Boschetti C, Carr A, Crisp A, Eyres I, Wang-Koh Y, Lubzens E, Barraclough TG, Micklem G & Tunnacliffe A 2012 'Biochemical Diversification through Foreign Gene Expression in Bdelloid Rotifers' PLoS Genetics 8, (11) e1003035-e1003035 , DOI
Tripathi R, Boschetti C, McGee B & Tunnacliffe A 2012 'Trafficking of bdelloid rotifer late embryogenesis abundant proteins' Journal of Experimental Biology 215, (16) 2786-2794 , DOI
Eyres I, Frangedakis E, Fontaneto D, Herniou EA, Boschetti C, Carr A, Micklem G, Tunnacliffe A & Barraclough TG 2012 'Multiple functionally divergent and conserved copies of alpha tubulin in bdelloid rotifers' BMC Evolutionary Biology 12, (1) 148-148 , DOI
Boschetti C, Pouchkina-Stantcheva N, Hoffmann P & Tunnacliffe A 2010 'Foreign genes and novel hydrophilic protein genes participate in the desiccation response of the bdelloid rotifer Adineta ricciae' Journal of Experimental Biology 214, (1) 59-68 , DOI
Boschetti C, Leasi F & Ricci C 2010 'Developmental stages in diapausing eggs: an investigation across monogonont rotifer species' Hydrobiologia 662, (1) 149-155 , DOI
Wang X, Boschetti C, Ruedas-Rama MJ, Tunnacliffe A & Hall EAH 2010 'Ratiometric pH-dot ANSors' The Analyst 135, (7) 1585-1585 , DOI
FONTANETO D, BOSCHETTI C & RICCI C 2008 'Cryptic diversification in ancient asexuals: evidence from the bdelloid rotifer Philodina flaviceps' Journal of Evolutionary Biology 21, (2) 580-587 , DOI
Chakrabortee S, Boschetti C, Walton LJ, Sarkar S, Rubinsztein DC & Tunnacliffe A 2007 'Hydrophilic protein associated with desiccation tolerance exhibits broad protein stabilization function' Proceedings of the National Academy of Sciences 104, (46) 18073-18078 , DOI
Pouchkina-Stantcheva NN, McGee BM, Boschetti C, Tolleter D, Chakrabortee S, Popova AV, Meersman F, Macherel D, Hincha DK & Tunnacliffe A 2007 'Functional Divergence of Former Alleles in an Ancient Asexual Invertebrate' Science 318, (5848) 268-271 , DOI
Fontaneto D, Herniou EA, Boschetti C, Caprioli M, Melone G, Ricci C & Barraclough TG 2007 'Independently Evolving Species in Asexual Bdelloid Rotifers' PLoS Biology 5, (4) e87-e87 , DOI
Boschetti C, Ricci C, Sotgia C & Fascio U 2005 'The Development of a Bdelloid Egg: A Contribution after 100 years' Hydrobiologia 546, (1) 323-331 , DOI
Ricci C, Caprioli M, Boschetti C & Santo N 2005 'Macrotrachela quadricornifera featured in a space experiment' Hydrobiologia 534, (1-3) 239-244 , DOI
Ricci C & Boschetti C 2003 'Bdelloid Rotifers as Model System to Study Developmental Biology in Space' 25-39 , DOI

Reports & invited lectures

Selected invited talks

Invited seminar, Stokes Society, Pembroke College, University of Cambridge (2019)

Invited plenary talk, International Congress on Invertebrate Pathology and Microbial Control and the 49th Annual Meeting of the Society for Invertebrate Pathology, Tours, France (2016)

Invited plenary talk, XIII International Symposium on Tardigrada, Modena, Italy (2015)

Selected seminar, Evolutionary Genetics & Genomics Symposium, University of Cambridge (2015)

Invited seminar, Crossing the Barriers lecture series - Evolution, University of Cambridge (2015)

Invited seminar, Department of Zoology, University of Cambridge (2015)