Professor Camille Carroll
Profiles

Professor Camille Carroll

Professor of Clinical Neuroscience

Peninsula Medical School (Faculty of Health)

Professor Camille Carroll can be contacted through arrangement with our Press Office, to speak to the media on these areas of expertise.
  • Clinical trials
  • Parkinson's disease
  • NIHR/CRN
  • Neuroprotection
  • Remote care pathways
  • Neurodegenerative disease
  • Health technology
Biography

Biography

  • Honorary Consultant Neurologist, Plymouth Hospitals NHS Trust
  • National Specialty Lead for Neurodegenerative Diseases NIHR CRN
  • Parkinson’s Specialty Lead and Cluster 4 Clinical Research Lead South West Peninsula CRN
  • Integrated Clinical Academic Training Lead

Qualifications

Dr Carroll is an academic consultant neurologist. She undertook her preclinical medical training at the University of Manchester, where she also completed an intercalated PhD (1994) investigating NMDA receptor antagonists in models of Parkinson's disease (PD). She completed her clinical training at the University of Oxford in 1997 and undertook specialist neurology training in the South West and West Midlands. In 2007 Dr Carroll was awarded a Medical Research Council fellowship which allowed her to develop research interests investigating neuroprotective mechanisms in cell culture models of Parkinson's disease.

Roles on external bodies

Dr Carroll sits on the Grant Assessment Panel 1 for Parkinson's UK, the Research Committee for the Cure Parkinson's Trust and the Linked Clinical Trials Committee. She has previously chaired the Data Monitoring Committee for the GDNF trial in Parkinson's disease. She is regional representative on the Association of British Neurologists Research Committee. She is a member of the Examination Board and Question Writing Group for the Neurology SCE.

Research

Research

Research interests

Dr Carroll's current research focus is on clinical trials of neuroprotective interventions in Parkinson's disease, currently being the chief investigator of a multi-centre clinical trial of simvastatin as a potential neuroprotective therapy in PD (PD-STAT). She also has an interest in the use of technology (wearable sensors and apps) for early disease detection, personalising therapy and monitoring disease progression. She has overseen the development of a PD DNA bank (2700 samples) and a regional PD clinical research register. She was appointed National Specialty Lead for Neurodegenerative Disease in 2017. She has been PD Speciality Lead, South West Peninsula CRN since April 2014, previously being joint PD Research Director for SW DeNDRoN (2010-2014). She was Chair of the Peninsula Parkinson’s Excellence Network (PenPEN) (2015-2017).

Within University Hospitals Plymouth NHS Trust, Dr Carroll leads development of the Parkinson’s disease service, which won a Parkinson's Excellence Network Award in 2017. She also leads a successful trial delivery team, overseeing a mixed portfolio of Parkinson's clinical studies - commercial and non-commercial, interventional and observational. 

Publications

Publications

Key publications

Key publications are highlighted

Journals
Articles
Gonzalez-Robles C, Weil RS, van Wamelen D, Bartlett M, Burnell M, Clarke CS, Hu MT, Huxford B, Jha A & Lambert C (2023) 'Outcome Measures for Disease-Modifying Trials in Parkinson’s Disease: Consensus Paper by the EJS ACT-PD Multi-Arm Multi-Stage Trial Initiative' Journal of Parkinson's Disease 13, (6) 1011-1033 , DOI
Martinez-Carrasco A, Real R, Lawton M, Iwaki H, Tan MMX, Wu L, Williams NM, Carroll C, Hu MTM & Grosset DG (2023) 'Genetic meta-analysis of levodopa induced dyskinesia in Parkinson’s disease' npj Parkinson's Disease 9, (1) , DOI
Aldred J, Freire-Alvarez E, Amelin AV, Antonini A, Bergmans B, Bergquist F, Bouchard M, Budur K, Carroll C & Chaudhuri KR (2023) 'Continuous Subcutaneous Foslevodopa/Foscarbidopa in Parkinson’s Disease: Safety and Efficacy Results From a 12-Month, Single-Arm, Open-Label, Phase 3 Study' Neurology and Therapy , DOI
Martínez Carrasco A, Real R, Lawton M, Hertfelder Reynolds R, Tan M, Wu L, Williams N, Carroll C, Corvol J-C & Hu M (2023) 'Genome-wide Analysis of Motor Progression in Parkinson Disease' Neurology Genetics 9, (5) e200092-e200092 , DOI
Sorrell L, Leta V, Barnett A, Stevens K, King A, Inches J, Kobylecki C, Walker R, Chaudhuri KR & Martin H (2023) 'Clinical features and outcomes of hospitalised patients with COVID-19 and Parkinsonian disorders: A multicentre UK-based study' PLOS ONE 18, (7) , DOI
Hall AM, Aroori S, Carroll CB, Meinert E & Allgar V (2023) 'Impact of digital technologies on self-efficacy in people with Parkinson’s: a scoping review protocol' BMJ Open 13, (3) , DOI
Foltynie T, Gandhi S, Gonzalez-Robles C, Zeissler M-L, Mills G, Barker R, Carpenter J, Schrag A, Schapira A & Bandmann O (2023) 'Towards a multi-arm multi-stage platform trial of disease modifying approaches in Parkinson’s disease' Brain 146, (7) 2717-2722 , DOI
Rochester L, Del Din S, Hu MT, Morgan C & Carroll C (2023) 'The challenges and opportunities for remotely evaluating movement disorders' 153-179 , DOI
Schrag A, Carroll C, Duncan G, Molloy S, Grover L, Hunter R, Brown R, Freemantle N, Whipps J & Serfaty MA (2022) 'Antidepressants Trial in Parkinson's Disease (ADepT-PD): protocol for a randomised placebo-controlled trial on the effectiveness of escitalopram and nortriptyline on depressive symptoms in Parkinson’s disease' BMC Neurology 22, (1) , DOI Open access
Stevens KN, Creanor S, Jeffery A, Whone A, Zajicek J, Foggo A, Jones B, Chapman R, Cocking L & Wilks J (2022) 'Evaluation of Simvastatin as a Disease-Modifying Treatment for Patients With Parkinson Disease' JAMA Neurology , DOI Open access
Carroll C (2022) 'Implications of research that excludes under-served populations' Nature Reviews Neurology , DOI
Day JO, Smith S, Noyce AJ, Alty J, Jeffery A, Chapman R & Carroll C (2022) 'Challenges of Incorporating Digital Health Technology Outcomes in a Clinical Trial: Experiences from PD STAT' Journal of Parkinson's Disease 1-5 , DOI Open access
Kehagia AA, North TK, Grose J, Jeffery AN, Cocking L, Chapman R & Carroll C (2022) 'Enhancing Trial Delivery in Parkinson’s Disease: Qualitative Insights from PD STAT' Journal of Parkinson's Disease 1-14 , DOI Open access
Schofield C, Chaudhuri KR, Carroll C, Sharma JC, Pavese N, Evans J, Foltynie T, Reichmann H, Zurowska L & Soares-da-Silva P (2022) 'Opicapone in UK clinical practice: effectiveness, safety and cost analysis in patients with Parkinson's disease' Neurodegenerative Disease Management 12, (2) 77-91 , DOI Open access
Masoli JAH, Down K, Nestor G, Hudson S, O’Brien JT, Williamson JD, Young CA & Carroll C (2021) 'A report from the NIHR UK working group on remote trial delivery for the COVID-19 pandemic and beyond' Trials 22, (1) , DOI Open access
van Wamelen DJ, Sringean J, Trivedi D, Carroll CB, Schrag AE, Odin P, Antonini A, Bloem BR, Bhidayasiri R & Chaudhuri KR (2021) 'Digital health technology for non-motor symptoms in people with Parkinson's disease: Futile or future?' Parkinsonism and Related Disorders , DOI Open access
Jost ST, Visser-Vandewalle V, Rizos A, Loehrer PA, Silverdale M, Evans J, Samuel M, Petry-Schmelzer JN, Sauerbier A & Gronostay A (2021) 'Non-motor predictors of 36-month quality of life after subthalamic stimulation in Parkinson disease' Parkinson's Disease 7, (1) , DOI Open access
Vijiaratnam N, Girges C, Auld G, Chau M, Maclagan K, King A, Skene S, Chowdhury K, Hibbert S & Morris H (2021) 'Exenatide once weekly over 2 years as a potential disease-modifying treatment for Parkinson’s disease: protocol for a multicentre, randomised, double blind, parallel group, placebo controlled, phase 3 trial: The ‘Exenatide-PD3’ study' BMJ Open 11, (5) e047993-e047993 , DOI Open access
Eke CS, Jammeh E, Li X, Carroll C, Pearson S & Ifeachor E (2021) 'Early Detection of Alzheimer's Disease with Blood Plasma Proteins Using Support Vector Machines' IEEE Journal of Biomedical and Health Informatics 25, (1) 218-226 , DOI Open access
Witham MD, Anderson E, Carroll C, Dark PM, Down K, Hall AS, Knee J, Maher ER, Maier RH & Mountain GA (2020) 'Ensuring that COVID-19 Research is Inclusive - guidance from the NIHR INCLUDE project' BMJ Open 10, (11) , DOI Open access
Dominey T, Kehagia AA, Gorst T, Pearson E, Murphy F, King E & Carroll C (2020) 'Introducing the Parkinson’s KinetiGraph into Routine Parkinson’s Disease Care: A 3-Year Single Centre Experience' Journal of Parkinson's Disease 10, (4) 1827-1832 , DOI Open access
Witham MD, Anderson E, Carroll C, Dark PM, Down K, Hall AS, Knee J, Maier RH, Mountain GA & Nestor G (2020) 'Developing a roadmap to improve trial delivery for underserved groups: results from a UK multi-stakeholder process' Trials , DOI Open access
Richardson SJ, Carroll C, Close J, Gordon AL, O'Brien J, Quinn TJ, Rochester L, Sayer AA, Shenkin SD & van der Velde N (2020) 'Research with older people in a world with COVID-19: identification of current and future priorities, challenges and opportunities' Age and Ageing , DOI Open access
Edwards E & Carroll C (2020) 'In reply to: Helmich and Bloem (2020) “The Impact of the COVID-19 Pandemic on Parkinson’s Disease: Hidden Sorrows and Emerging Opportunities”' Journal of Parkinson's Disease 1-2 , DOI Open access
Barker RA, Bjorklund A, Gash DM, Whone A, Van Laar A, Kordower JH, Bankiewicz K, Kieburtz K, Saarma M & Booms S (2020) 'GDNF and Parkinson’s Disease: Where Next? A Summary from a Recent Workshop' Journal of Parkinson's Disease 1-17 , DOI Open access
Zeissler M-L, Li V, Parmar MKB & Carroll CB (2020) 'Is It Possible to Conduct a Multi-Arm Multi-Stage Platform Trial in Parkinson’s Disease: Lessons Learned from Other Neurodegenerative Disorders and Cancer' Journal of Parkinson's Disease 10, (2) 413-428 , DOI Open access
Kelly J, Moyeed R, Carroll C, Luo S & Li X (2020) 'Genetic networks in Parkinson’s and Alzheimer’s disease' Aging , DOI Open access
Reichmann H, Lees A, Rocha J-F, Magalhães D & Soares-da-Silva P (2020) 'Effectiveness and safety of opicapone in Parkinson’s disease patients with motor fluctuations: the OPTIPARK open-label study' Translational Neurodegeneration 9, (1) , DOI Open access
Williams NM, Hubbard L, Sandor C, Webber C, Hendry H, Carroll C, Lawton M, Chaudhuri KR, Morris H & Hu MT (2020) 'Genome-wide association study of pain in Parkinson's disease implicates TRPM8 as a risk factor' Movement Disorders , DOI Open access
Soundy A, Collett J, Lawrie S, Coe S, Roberts H, Hu M, Bromley S, Harling P, Reed A & Coeberg J (2019) 'A qualitative study on the impact of First Steps- a peer-led, educational intervention for people newly diagnosed with Parkinson’s Disease' Behavioral Sciences , DOI Open access
Carroll C, Webb D, Stevens ??? KN, Vickery J, Eyre V, Ball S, Wyse R, Webber M, Foggo A & Zajicek J (2019) 'Simvastatin as a neuroprotective treatment for Parkinson’s disease (PD STAT): protocol for a double-blind, randomised, placebo-controlled futility study' BMJ Open , DOI Open access
Carroll C, Kobylecki C, Silverdale M & Thomas C (2019) 'Impact of Quantitative Assessment of Parkinson’s Disease-Associated Symptoms Using Wearable Technology on Treatment Decisions' Journal of Parkinson's Disease 9, (3) 601-601 , DOI Open access
Carroll CB, Wyse RKH & Grosset DG (2019) 'Statins and Parkinson's: A complex interaction' Movement Disorders 34, (7) 934-935 , DOI Open access
Trivedi DK, Sinclair E, Xu Y, Sarkar D, Walton-Doyle C, Liscio C, Banks P, Milne J, Silverdale M & Kunath T (2019) 'Discovery of Volatile Biomarkers of Parkinson’s Disease from Sebum' ACS Central Science 5, (4) 599-606 , DOI Open access
Kelly J, Moyeed R, Carroll C, Albani D & Li X (2019) 'Gene expression meta-analysis of Parkinson's disease and its relationship with Alzheimer's disease' Molecular Brain 12, (1) 0-0 , DOI Open access
Martinez-Martin P, Rizos AM, Wetmore JB, Antonini A, Odin P, Pal S, Sophia R, Carroll C, Martino D & Falup-Pecurariu C (2018) 'Relationship of Nocturnal Sleep Dysfunction and Pain Subtypes in Parkinson's Disease' Movement Disorders Clinical Practice , DOI Open access
Carroll CB, Fackrell R, Grosset D, Mohamed B, Reddy P, Parry M, Chaudhuri K & Foltynie T (2018) 'Noninvasive options for ‘wearing-off’ in Parkinson's disease: a clinical consensus from a panel of UK Parkinson's disease specialists' Neurodegenerative Disease Management Open access
Eke CS, Jammeh E, Li X, Carroll C, Pearson S & Ifeachor E (2018) 'Identification of Optimum Panel of Blood-based Biomarkers for Alzheimer’s Disease Diagnosis Using Machine Learning' 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) , DOI Open access
Jammeh EA, Carroll CB, Pearson SW, Escudero J, Anastasiou A, Zhao P, Chenore T, Zajicek J & Ifeachor E (2018) 'Machine-learning based identification of undiagnosed dementia in primary care: a feasibility study' BJGP Open 2, (2) 0-0 , DOI Open access
Ramaswamy B, Jones J & Carroll C (2018) 'Exercise for people with Parkinson’s: a practical approach' Practical Neurology 18, (5) , DOI Open access
Martinez-Martin P, Rizos AM, Wetmore J, Antonini A, Odin P, Pal S, Sophia R, Carroll C, Martino D & Falup-Pecurariu C (2018) 'First comprehensive tool for screening pain in Parkinson's disease: The King's Parkinson's Disease Pain Questionnaire (KPPQ)' European Journal of Neurology 25, (10) 1255-1261 Author Site , DOI Open access
Carroll CB & Wyse RKH (2017) 'Simvastatin as a Potential Disease-Modifying Therapy for Patients with Parkinson’s Disease: Rationale for Clinical Trial, and Current Progress' Journal of Parkinson's Disease , DOI Open access
Lubbe SJ, Escott-Price V, Brice A, Gasser T, Pittman AM, Bras J, Hardy J, Heutink P, Wood NM & Singleton AB (2016) 'Rare variants analysis of cutaneous malignant melanoma genes in Parkinson's disease' Neurobiology of Aging 48, 222.e1-222.e7 , DOI Open access
Jammeh E, Zhao P, Carroll C, Pearson S & Ifeachor E (2016) 'Identification of blood biomarkers for use in point of care diagnosis tool for Alzheimer's disease' 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) , DOI Open access
Jammeh E, Zhao P, Carroll C, Pearson S & Ifeachor E (2016) 'Identification of blood biomarkers for use in point of care diagnosis tool for Alzheimer's disease' Annu Int Conf IEEE Eng Med Biol Soc 2016, 2415-2418 Author Site , DOI
Zeissler M-L, Eastwood J, McCorry K, Hanemann OC, Zajicek JP & Carroll CB (2016) 'Delta-9-tetrahydrocannabinol protects against MPP+ toxicity in SH-SY5Y cells by restoring proteins involved in mitochondrial biogenesis' Oncotarget , DOI Open access
Rizos A, Martinez-Martin P, Pal S, Carroll C, Martino D, Sophia R, Falup-Pecurariu C, Kessel B, Sauerbier A & Martin A (2016) 'The First Parkinson's Disease Pain Questionnaire (King's PD Pain Quest) – an interim analysis of a multicentre study of the patient's perspective' Parkinsonism & Related Disorders 22, e41-e41 , DOI
Chaudhuri KR, Rizos A, Trenkwalder C, Rascol O, Pal S, Martino D, Carroll C, Paviour D, Falup-Pecurariu C & Kessel B (2015) 'King's Parkinson's disease pain scale, the first scale for pain in PD: An international validation' Movement Disorders 30, (12) 1623-1631 , DOI Open access
Kamel Boulos MN, Ifeachor E, Escudero Rodriguez J, Zhao P, Carroll CB, Costa P, Doppler G, Carrasco L, Spiru L & Helga K (2015) 'LiveWell - Promoting Healthy Living and Wellbeing for Parkinson Patients Through Social Network and ICT Training: Lessons Learnt and Best Practices' International Journal of Healthcare Information Systems and Informatics
Cooke T, Carroll C, Zajicek J, Ellard S & Morrison K (2013) 'Molecular genetic studies of neurodegenerative disease' J Neurol Neurosurg Psychiatry 84, (11) Author Site , DOI Open access
Zeissler ML, Eastwood J, Oliver Hanemann C, Zajicek J & Carroll C (2013) 'Δ9-TETRAHYDROCANNABINOL IS PROTECTIVE THROUGH PPARγ DEPENDENT MITOCHONDRIAL BIOGENESIS IN A CELL CULTURE MODEL OF PARKINSON'S DISEASE' J Neurol Neurosurg Psychiatry 84, (11) Author Site , DOI Open access
Hilton D, Stephens M, Kirk L, Edwards P, Potter R, Zajicek J, Broughton E, Hagan H & Carroll C (2013) 'Accumulation of α-synuclein in the bowel of patients in the pre-clinical phase of Parkinson’s disease' Acta Neuropathologica 1-7 Author Site , DOI
Ammoun S, Schmid MC, Ristic N, Zhou L, Hilton D, Ercolano E, Carroll C & Hanemann CO (2012) 'The role of insulin-like growth factors signaling in merlin-deficient human schwannomas' Glia 60, (11) 1721-1733 Author Site , DOI Open access
Carroll CB, Zeissler M-L, Hanemann CO & Zajicek JP (2012) 'Δ<sup>9</sup>-tetrahydrocannabinol (Δ<sup>9</sup>-THC) exerts a direct neuroprotective effect in a human cell culture model of Parkinson's disease' Neuropathology and Applied Neurobiology 38, (6) 535-547 , DOI
Carroll C, Palmer A, Cosby C & Zajicek J (2012) 'Analysis and validation of a Parkinson's disease register as a recruitment tool for clinical studies' Clin Med (Lond) 12, (3) 210-215 Author Site , DOI Open access
Carroll CB, Palmer A, Cosby C & Zajicek JP (2011) 'Analysis and validation of a Parkinson's disease register as a recruitment tool for clinical studies' Trials 12 Suppl 1, , DOI
Carroll CB, Zeissler M-L, Chadborn N, Gibson K, Williams G, Zajicek JP, Morrison KE & Hanemann CO (2011) 'Changes in iron-regulatory gene expression occur in human cell culture models of Parkinson's disease' Neurochem Int 59, (1) 73-80 Author Site , DOI Open access
Carroll CB & Zajicek JP (2011) 'Designing clinical trials in older people' Maturitas 68, (4) 337-341 Author Site , DOI Open access
Carroll C, Krolikowski K, Mukonoweshuro W, Jones J & Hanemann CO (2010) 'Unilateral cerebral hemisphere oedema as a peri-ictal phenomenon' J Neurol 257, (12) 2094-2096 Author Site , DOI
Carroll CB, Zeissler ML, Chadborn N, Gibson K, Williams GJ, Morrison KE, Zajicek JP & Hanemann CO (2010) 'Changes in Iron-Regulatory Gene Expression Occur in Human Cell Culture Models of PD' MOVEMENT DISORDERS 25, S628-S628 Author Site Open access
Zeissler, Carroll CB & Zajicek J (2010) 'CBD & D9-THC - the two faces of cannabis' Cell Science 7, (1) Open access
Sinclair AJ, Carroll C & Davies B (2009) 'Cauda equina syndrome following a lumbar puncture' J Clin Neurosci 16, (5) 714-716 Author Site , DOI Open access
Katzenschlager R, Schrag A, Evans A, Manson A, Carroll CB, Ottaviani D, Lees AJ & Hobart J (2007) 'Quantifying the impact of dyskinesias in PD: the PDYS-26: a patient-based outcome measure' Neurology 69, (6) 555-563 Author Site , DOI
Carroll CB, Tengah DSNAP, Lawthom C & Venables G (2007) 'The feminisation of British neurology: implications for workforce planning' Clin Med (Lond) 7, (4) 339-342 Author Site , DOI Open access
Goodall EF, Greenway MJ, van Marion I, Carroll CB, Hardiman O & Morrison KE (2005) 'Association of the H63D polymorphism in the hemochromatosis gene with sporadic ALS' Neurology 65, (6) 934-937 Author Site , DOI
Liu XG, Carroll CB, Wang SY, Zajicek J & Bain PG (2005) 'Quantifying drug-induced dyskinesias in the arms using digitised spiral-drawing tasks' JOURNAL OF NEUROSCIENCE METHODS 144, (1) 47-52 Author Site , DOI Open access
Carroll CB, Hilton DA, Hamon M & Zajicek JP (2005) 'Muscle cramps and weakness secondary to graft versus host disease fasciitis' Eur J Neurol 12, (4) 320-322 Author Site , DOI Open access
McSherry JW, Carroll CB, Zajicek J, Teare L & Bain P (2005) 'Cannabis for dyskinesia in Parkinson disease: A randomized double-blind crossover study' Neurology 64, (6) 1100-1100 , DOI
Carroll CB, Bain PG, Teare L, Liu X, Joint C, Wroath C, Parkin SG, Fox P, Wright D & Hobart J (2004) 'Cannabis for dyskinesia in Parkinson disease: a randomized double-blind crossover study' Neurology 63, (7) 1245-1250 Author Site , DOI
Carroll CB & Zajicek JP (2004) 'The 'harlequin' sign in association with multiple sclerosis' JOURNAL OF NEUROLOGY 251, (9) 1145-1146 Author Site , DOI
Carroll CB & Bain PG (2004) 'Do on-off variations cause discrepancies in the historical items of the UPDRS?' MOVEMENT DISORDERS 19, (5) 605-605 Author Site , DOI Open access
Fox P, Bain PG, Glickman S, Carroll C & Zajicek J (2004) 'The effect of cannabis on tremor in patients with multiple sclerosis' Neurology 62, (7) 1105-1109 Author Site , DOI
Carroll C, Hobart J, Fox C, Teare L & Gibson J (2004) 'Stroke in Devon: knowledge was good, but action was poor' J Neurol Neurosurg Psychiatry 75, (4) 567-571 Author Site , DOI Open access
Carroll C & Zajicek J (2004) 'Provision of 24 hour acute neurology care by neurologists: manpower requirements in the UK' J Neurol Neurosurg Psychiatry 75, (3) 406-409 Author Site , DOI Open access
Carroll CB & Gardner-Thorpe C (2004) 'Charles Karsner Mills (1845-1931) and his syndrome' Some Aspects of History of Neuroscience 35-36
Hadjikoutis S, Carroll CB & Plant GTP (2004) 'Raised intracranial pressure presenting with spontaneous periorbital bruising: two case reports' Journal of Neurology, Neurosurgery and Psychiatry 75, (8) Open access
Weeks RA, Scaravilli F, Lees AJ, Carroll CB, Husain M & Rudge P (2002) 'Cerebral amyloid angiopathy and motor neurone disease presenting with a progressive supranuclear palsy-like syndrome' Movement Disorders 18, (3)
Faccenda KA & Finucane BT (2001) 'Complications of Regional Anaesthesia' Drug Safety 24, (6) 413-442 , DOI
Cooper AJ, Carroll CB & Mitchell IJ (1998) 'Glutamate antagonists for Parkinson's disease - Rationale for use and therapeutic implications' CNS DRUGS 9, (6) 421-429 Author Site , DOI
Scott R (1998) 'Neuropsychological, neurological and functional outcome following pallidotomy for Parkinson's disease. A consecutive series of eight simultaneous bilateral and twelve unilateral procedures' Brain 121, (4) 659-675 , DOI
Carroll CB, Scott R, Davies LE & Aziz T (1998) 'The pallidotomy debate' British Journal of Neurosurgery 2, (12)
B. CARROLL C, SCOTT R, DAVIES LE & AZIZ T (1998) 'The pallidotomy debate' British Journal of Neurosurgery 12, (2) 146-150 , DOI
Biousse V, Newman NJ, Carroll CB, Mewes K, Vitek JL, Bakay RAE, Baron MS & DeLong MR (1998) 'Visual fields in patients with posterior GPi pallidotomy'
Mitchell IJ & Carroll CB (1997) 'Reversal of parkinsonian symptoms in primates by antagonism of excitatory amino acid transmission: potential mechanisms of action' Neurosci Biobehav Rev 21, (4) 469-475 Author Site , DOI Open access
MITCHELL IJ, HUGHES N, CARROLL CB & BROTCHIE JM (1995) 'REVERSAL OF PARKINSONIAN SYMPTOMS BY INTRASTRIATAL AND SYSTEMIC MANIPULATIONS OF EXCITATORY AMINO-ACID AND DOPAMINE TRANSMISSION IN THE BILATERAL 6-OHDA LESIONED MARMOSET' BEHAVIOURAL PHARMACOLOGY 6, (5-6) 492-507 Author Site
CARROLL CB, HOLLOWAY V, BROTCHIE JM & MITCHELL IJ (1995) 'NEUROCHEMICAL AND BEHAVIORAL INVESTIGATIONS OF THE NMDA RECEPTOR-ASSOCIATED GLYCINE SITE IN THE RAT STRIATUM - FUNCTIONAL IMPLICATIONS FOR TREATMENT OF PARKINSONIAN SYMPTOMS' PSYCHOPHARMACOLOGY 119, (1) 55-65 Author Site , DOI
Brotchie JM, Crossman ARC, Mitchell IJ, Duty S, Carroll CB, Cooper AJC, Henry B, Hughes N & Maneuf Y (1993) 'Chemical signalling in the globus pallidus in parkinsonism' Progress in Brain Research (99) 125-139
Chapters
Langley J, Partridge R, Ankeny U, Wheeler G & Carroll C (2022) 'Co-designing Resources for Knowledge-Based Self-reflection for People Living with Parkinson’s Disease to Better Enable Independent Living' Springer Series in Design and Innovation Springer International Publishing 237-251 , DOI
Kelly J, Moyeed R, Carroll C, Albani D & Li X (2020) 'Gene Expression Meta-Analysis of Parkinson’s disease and its Relationship with Alzheimer’s disease' Prime Archives in Molecular Biology Vide Leaf, Hyderabad , DOI
Conference Papers
Pujara P, Rideout J & Carroll C (2016) 'IMPROVING PROVISION OF PARKINSON'S DISEASE EXERCISE CLASSES' BMJ e1.14-e1 , DOI
Blight B, Davis J, Evans V, Hawkes N & Carroll C (2016) 'IMPROVING THE EXPERIENCE OF DIAGNOSIS IN PARKINSON'S DISEASE' BMJ e1.234-e1 , DOI
Dominey T, Newman C, Carroll C, Noad R, Appleyard B, Deeprose C & Hall S (2016) 'PD-TAP: AN OBJECTIVE AND AUTOMATED MEASURE OF PARKINSON'S DISEASE SEVERITY' BMJ e1.237-e1 , DOI
Stamford J, Isaacs T & Carroll C (2015) 'People with Parkinson's design clinical trials charter to improve communication about, recruitment to and retention in Parkinson's clinical trials' Springer Science and Business Media LLC , DOI
Creanor S, Vickery J, Eyre V, Zajicek J, Ball S, Elm J & Carroll C (2015) 'Two-arm randomised futility trials: PD-stat - a futility trial of a potential neuroprotective treatment in people with Parkinson's disease' Springer Science and Business Media LLC , DOI
Noad R, Newman C, Carroll C & Zajicek J (2015) 'iPAD-BASED ASSESSMENT IN PARKINSON'S DISEASE' BMJ e4.189-e4 , DOI
Koopman H, Jackson S, Anichtchik O & Carroll C (2015) 'LPS INDUCES AGGREGATION OF α-SYNUCLEIN IN MONOCYTES' BMJ e4.188-e4 , DOI
Jammeh E, Carroll C, Pearson S, Escudero J, Anastasiou A, Zajicek J & Ifeachor E (2015) 'USING NHS PRIMARY CARE DATA TO IDENTIFY UNDIAGNOSED DEMENTIA' BMJ e4.134-e4 , DOI
Hilton DA, Stephens M, Zajicek J, Broughton E, Hagan H, Edwards P & Carroll C (2013) 'Accumulation of alpha synuclein in the bowel in preclinical Parkinson's disease' 11-11
Hilton DA, Zeissler ML, Zhang H, Zajicek J, Hicks J, Eastwood J & Carroll C (2013) 'Cannabinoid receptor expression in Parkinson's disease' 34-35
Zeissler M, Hanemann CO, Zajicek JP & Carroll CB (2012) 'FAAH INHIBITION IS PROTECTIVE IN A CELL CULTURE MODEL OF PARKINSON'S DISEASE' , DOI
Salter E, Zeissler ML, Alexander SPH, Hanemann CO, Zajicek JP & Carroll CB (2012) 'ENDOCANNABINOID TOXICITY IN A CELL CULTURE MODEL OF PARKINSON'S DISEASE' BMJ A13.4-A14 , DOI
Zeissler ML, Hanemann O, Zajicek JP & Carroll CB (2012) 'Delta(9)-THC is protective in a cell culture model of Parkinson's disease through a PPAR gamma mediated mechanism resulting in increased expression of PGC1-alpha' S39-S39
Zeissler M, Carroll CB, Hanemann CO & Zajieck JP (2012) '108 Investigating the neuroprotective properties of Δ9-THC in a cell culture model of Parkinson's disease' BMJ e1.58-e1 , DOI
Carroll C, Zajicek JP, Hanemann CO, Stone V & Zeissler M (2010) 'CANNABINOIDS ARE NEUROPROTECTIVE IN A HUMAN CELL CULTURE MODEL OF PARKINSON'S DISEASE' E60-E60 , DOI
Carroll C, Williams GJ, Chadborn NH, Hanemann CO, Zajicek JP, Morrison KE, Gibson K & Zeissler M (2010) 'CHANGES IN IRON-REGULATORY GENE EXPRESSION OCCUR IN HUMAN CELL CULTURE MODELS OF PARKINSON'S DISEASE' E29-E29 , DOI
Carroll CB, Chadborn N, Hanemann O & Zajicek J (2009) 'CANNABINOIDS ARE NEUROPROTECTIVE IN A CELL CULTURE MODEL OF PARKINSON'S DISEASE' , DOI
Sinclair AJ, Carroll C & Davies MB (2007) 'A rare complication of a common procedure: Acute cauda equina syndrome following a lumbar puncture' 218-218
Carroll CB, Majumdar D, Winer JB & Davies NP (2005) 'Childhood onset demyelinating neuropathy and cataracts: A potentially treatable disorder' 1323-1324
Carroll CB & Zajicek JP (2005) 'Clinical viral encephalitis in adults: A 10 year retrospective study' 157-158
Carroll CB & Zajicek JZ (2003) 'Meeting the Association of British Neurologists guidelines: Provision of 24 hour acute neurology care by neurologists' 1453-1453
Carroll C, Hobart J, Fox C, Teare L & Gibson J (2003) 'Stroke in Devon: The need to translate knowledge into action' 1176-1177
Carroll C & Gardner-Thorpe C (2003) 'Charles Karsner Mills (1845-1931) and his syndrome' 406-406
Presentations and posters
Carroll CB, Zeissler ML, Stone V, Hanemann CO & Zajicek JP Carroll CB, Zeissler ML, Stone V, Hanemann CO & Zajicek JP 'Cannabinoids Are Neuroprotective in a Human Cell Culture Model of Parkinson's Disease' Author Site Open access
Aldred J, Amelin A, Antonini A, Bergmans B, Bergquist F, Bouchard M, Budur K, Carroll C, Chaudhuri K & Criswell S Aldred J, Amelin A, Antonini A, Bergmans B, Bergquist F, Bouchard M, Budur K, Carroll C, Chaudhuri K & Criswell S 'Continuous Subcutaneous Foslevodopa/Foscarbidopa in Advanced Parkinson's Disease: Results From a 12-Month Phase 3 Study' Author Site , DOI
Isaacson S, Di Lorenzo G, Facheris M, Fung V, Henriksen T, Ikenaka K, Jia J, Kern D, Kukreja P & Santos Garcia D Isaacson S, Di Lorenzo G, Facheris M, Fung V, Henriksen T, Ikenaka K, Jia J, Kern D, Kukreja P & Santos Garcia D 'Subcutaneous Foslevodopa/Foscarbidopa in Parkinson's Disease: Results by Age, Disease Duration, and Baseline "Off" Time' Author Site , DOI
Mueller M, Cosman J, Adams JL, Badawy R, Bhatnagar R, Bloem B, Carroll C, Cooray N, Dam T & Dexter DT Mueller M, Cosman J, Adams JL, Badawy R, Bhatnagar R, Bloem B, Carroll C, Cooray N, Dam T & Dexter DT 'Interaction with Regulatory Agencies Worldwide to Advance the Use of Digital Health Technology in Parkinson's Disease Clinical Research: the Critical Path for Parkinson's Pre-Competitive 3DT Initiative' , DOI
Carroll C, Lees A, Ferreira J, Fonseca M, Magalhães D, Rocha J & Soares-Da-Silva P Carroll C, Lees A, Ferreira J, Fonseca M, Magalhães D, Rocha J & Soares-Da-Silva P 'Impact of 3-month earlier versus later initiation of opicapone versus entacapone in levodopa-treated patients with Parkinson's disease and motor fluctuations' , DOI
Carroll C, Lees A, Ferreira J, Fonseca M, Magalhaes D, Rocha J-F & Soares-da-Silva P Carroll C, Lees A, Ferreira J, Fonseca M, Magalhaes D, Rocha J-F & Soares-da-Silva P 'Impact of 3-month early versus postponed initiation of opicapone vs entacapone in Parkinson's levodopa-treated patients' Author Site , DOI
Carroll C, Lees A, Reichmann H, Martins D, Magalhaes D, Rocha J & Soares-da-Silva P Carroll C, Lees A, Reichmann H, Martins D, Magalhaes D, Rocha J & Soares-da-Silva P 'Influence of levodopa daily dose in Opicapone effectiveness in Parkinson's: the real-world OPTIPARK study' Author Site , DOI
Gorst T, Dominey T, Whipps J, Whipps S, Cooke J, Mullin S, Maramba I, Edwards E & Carroll C Gorst T, Dominey T, Whipps J, Whipps S, Cooke J, Mullin S, Maramba I, Edwards E & Carroll C 'Not so simple: the challenge of developing a non-motor symptoms app (NMS Assist) for people with Parkinson's (PwP)' Author Site Open access
Dominey T, Mullin S, Edwards E, Whipps J, Whipps S & Carroll C Dominey T, Mullin S, Edwards E, Whipps J, Whipps S & Carroll C '137 Usability testing of a non-motor symptom app in PD' , DOI Open access
King E, Inches J, Edwards E, Rideout J, Whipps S, Holley M, Gorst T & Carroll C King E, Inches J, Edwards E, Rideout J, Whipps S, Holley M, Gorst T & Carroll C '023  Evaluating a home-based care pathway for people with Parkinson’s disease' , DOI
Zeissler M-L, McFarthing K, Gonzalez-Robles C, Chapman R, Mills G, Foltynie T & Carroll C Zeissler M-L, McFarthing K, Gonzalez-Robles C, Chapman R, Mills G, Foltynie T & Carroll C '109 Embedding patient voice in trial design: the EJS ACT-PD experience' , DOI
Zeissler M-L, Dominey T, Morris H, Bandmann O, Schrag A, Foltynie T & Carroll C Zeissler M-L, Dominey T, Morris H, Bandmann O, Schrag A, Foltynie T & Carroll C '233  Working towards an adaptive trial platform for Parkinson’s disease' , DOI
Edwards E, Triscott K, Ankeny U, Langley J, Partridge R, Swabey M, Rideout J, Whipps S, Whipps J & Carroll C Edwards E, Triscott K, Ankeny U, Langley J, Partridge R, Swabey M, Rideout J, Whipps S, Whipps J & Carroll C '237  Designing and implementing a home based care pathway for people with Parkinson’s disease' , DOI
Thomas C, Mohammed B, Abdelgadir E, Silverdale MA, Kobylecki C, Osborne L, Smith M, Hulejczuk A, Saha AR & Bain PG Thomas C, Mohammed B, Abdelgadir E, Silverdale MA, Kobylecki C, Osborne L, Smith M, Hulejczuk A, Saha AR & Bain PG 'Can implementation of technology transform the management of Parkinson's? Lessons learnt from the Parkinson's KinetiGraph (TM) (PKG (TM)) service evaluation project' Author Site Open access
Chloe TLY, Dominey T, Pearson E, Murphy F & Carroll C Chloe TLY, Dominey T, Pearson E, Murphy F & Carroll C 'Designing a care pathway for high risk parkinson’s patients' , DOI Open access
Courtman M, Mullin S, Ifeachor E, Sun L, Carroll C, McGavin L & Thurston M Courtman M, Mullin S, Ifeachor E, Sun L, Carroll C, McGavin L & Thurston M 'Artificial Intelligence based detection of Parkinson’s disease in magnetic resonance imaging brain scans'
Cheesman A, Blackburn D, Carroll C, Cohen A, Coebergh J, Sokhi D, Wong SH & Woolmore J Cheesman A, Blackburn D, Carroll C, Cohen A, Coebergh J, Sokhi D, Wong SH & Woolmore J '11.39 Association of british neurologists sustainability special interest group (ABN sustainability SIG): formation, objectives and invitation' , DOI Open access
Hutchinson L, Dominey T, Pearson E, Murphy F, Bell L & Carroll C Hutchinson L, Dominey T, Pearson E, Murphy F, Bell L & Carroll C 'Evaluating the clinical utility of the parkinson’s kinetigraph (PKG)' , DOI Open access
Edwards E, Partridge R, Ankeny U, Langley J, Whipps S, Whipps J, Rideout J, Evans A, Bentley S & Swabey M Edwards E, Partridge R, Ankeny U, Langley J, Whipps S, Whipps J, Rideout J, Evans A, Bentley S & Swabey M 'Home Based Care: A care pathway innovation for Parkinson's disease' Author Site Open access
Palin M, Rideout J, Carroll C & Evans V Palin M, Rideout J, Carroll C & Evans V 'Improving community exercise provision in Parkinson’s' , DOI Open access
Abdelgadir E, Patel D, O’Gara M, Leach O, Masri OA, Bhattacharjee S, Shah A, Talbot J, Zafar H & Carroll C Abdelgadir E, Patel D, O’Gara M, Leach O, Masri OA, Bhattacharjee S, Shah A, Talbot J, Zafar H & Carroll C 'PO001 Successful neurology trainee research network collaborative audit' , DOI Open access
Robinson A, Pearson E, Murphy F, Davis J & Carroll C Robinson A, Pearson E, Murphy F, Davis J & Carroll C 'PO077 Evaluating a nurse-led diagnosis pathway in parkinson’s disease' , DOI Open access
Abdelgadir E, Patel D, O’Gara M, Leach O, Masri OA, Bhattacharjee S, Shah A, Talbot J, Zafar H & Carroll C Abdelgadir E, Patel D, O’Gara M, Leach O, Masri OA, Bhattacharjee S, Shah A, Talbot J, Zafar H & Carroll C 'PO213 Sonar identifies research training needs in a clinical training program' , DOI Open access
Shaw N, Evans V, Rideout J & Carroll C Shaw N, Evans V, Rideout J & Carroll C 'PO219 Guidelines for pd patient involvement in service development' , DOI Open access
Abdelgadir E, Almasri O, Bhattacharjee S, Leach O, O'gara M, Patel D, Shah A, Talbot J, Zafar H & Carroll C Abdelgadir E, Almasri O, Bhattacharjee S, Leach O, O'gara M, Patel D, Shah A, Talbot J, Zafar H & Carroll C 'SONAR identifies registrar research training needs in a clinical training program' Author Site
Abdelgadir E, Almasri O, Bhattacharjee S, Patel D, O'gara M, Leach O, Shah A, Talbot J, Zafar H & Carroll C Abdelgadir E, Almasri O, Bhattacharjee S, Patel D, O'gara M, Leach O, Shah A, Talbot J, Zafar H & Carroll C 'Successful neurology trainee research network collaborative audit' Author Site
Zeissler M, Windle R, McFarthing K, Raphael K, Rafaloff G & Carroll C Zeissler M, Windle R, McFarthing K, Raphael K, Rafaloff G & Carroll C 'Using a Delphi process to inform the design of disease modifying trials in Parkinson's disease' Author Site Open access
Sorrell L, King A, Inches J, Rideout J, Sneyd JR, Kobylecki C, Chaudhuri R, Walker R, Martin H & Carroll C Sorrell L, King A, Inches J, Rideout J, Sneyd JR, Kobylecki C, Chaudhuri R, Walker R, Martin H & Carroll C 'Outcome and mortality of hospital admission with COVID-19 for individuals with parkinsonian syndromes' , DOI
Carroll C, Lees A, Reichmann H, Martins D, Magalhães D, Rocha J & Soares-Da-Silva P Carroll C, Lees A, Reichmann H, Martins D, Magalhães D, Rocha J & Soares-Da-Silva P 'Influence of levodopa daily dose on the effectiveness of opicapone in Parkinson's disease patients with motor fluctuations: Findings from the real-world OPTIPARK study' , DOI