Dr Camille Carroll

Research interests

I have experience of behavioural pharmacology in animal models of Parkinson’s disease, and more recently have developed an interest in mechanisms of cell death and neuroprotective strategies. I have established a PD cell culture model which we utilize to investigate the neuroprotective effects of cannabinoids and endocannabinoid modulators, focusing on the intracellular downstream mechanisms mediating their effects. I have active collaborations locally and nationally investigating other aspects of PD pathogenesis including pre-symptomatic bowel alpha-synuclein expression, lysosomal pathways in Drosphila and verifying our cell culture findings in an in vivo mouse model. I currently co-supervise 2 PhD students and several placement students. I have previously contributed to studies of surgical intervention in Parkinson’s disease (PD), both in the UK and in the US, and planned and managed a clinical trial of cannabinoids for symptomatic therapy in PD. I am currently part of the NIHR-funded team investigating clinical trial methodology in neurodegenerative diseases, investigating outcome measures of various parameters in PD. I am joint PD research director for SW DeNDRoN and as such have responsibility for overseeing clinical research capability in the Peninsula and the development of a balanced clinical trial portfolio. I am PI on a number of clinical studies and have overseen the development of a PD DNA bank (1500 samples) and PD clinical research register.

Research groups

• Clinical Neuroscience