Dr Amiya Patra
Profiles

Dr Amiya Patra

Lecturer in Cancer Immunity

Peninsula Medical School (Faculty of Medicine and Dentistry)

Role

Research

Teaching
Supervision

Qualifications

Ph. D.


Immunology

Professional membership

International Society for Interferon and Cytokine Research (ISICR)

International Cytokine Society (ICS)
German Society for Immunology (DGFI)
European Association for Cancer Research (EACR)

Research interests

Haematopoietic stem cell maintenance and lineage differentiation

Lymphocyte development
Erythropoiesis and anemia
Cancer
Cytokine signaling

Grants & contracts

1. PostDocPlus Funding, 2014, University of Wuerzburg, Wuerzburg, Germany.

2. German Jose Carreras Leukemia Foundation (DJCLS), 2015.

Key publications are highlighted

Journals
Articles
Giampaolo S, Wójcik G, Klein-Hessling S, Serfling E & Patra AK 2018 'B cell development is critically dependent on NFATc1 activity' Cellular & Molecular Immunology , DOI PEARL
Giampaolo S, Wójcik G, Klein-Hessling S, Serfling E & Patra AK 2018 'NFAT-mediated defects in erythropoiesis cause anemia in Il2-/- mice' Oncotarget 9, (11) 9632-9644 Author Site , DOI PEARL
Klein-Hessling S, Muhammad K, Klein M, Pusch T, Rudolf R, Flöter J, Qureischi M, Beilhack A, Vaeth M & Kummerow C 2017 'NFATc1 controls the cytotoxicity of CD8+ T cells' Nature Communications 8, (1) , DOI PEARL
Giampaolo S, Wójcik G, Serfling E & Patra AK 2017 'Interleukin-2-regulatory T cell axis critically regulates maintenance of hematopoietic stem cells' Oncotarget , DOI PEARL
Alrefai H, Muhammad K, Rudolf R, Pham DAT, Klein-Hessling S, Patra AK, Avots A, Bukur V, Sahin U & Tenzer S 2016 'Corrigendum: NFATc1 supports imiquimod-induced skin inflammation by suppressing IL-10 synthesis in B cells' Nature Communications 7, 12421-12421 , DOI PEARL
Patra AK 2016 'A threshold level of NFATc1 activity facilitates thymocyte differentiation and opposes notch-driven leukaemia development' Nature Communications , DOI PEARL
Alrefai H, Muhammad K, Rudolf R, Pham DAT, Klein-Hessling S, Patra AK, Avots A, Bukur V, Sahin U & Tenzer S 2016 'NFATc1 supports imiquimod-induced skin inflammation by suppressing IL-10 synthesis in B cells' Nature Communications 7, 11724-11724 , DOI PEARL
Busch R, Murti K, Liu J, Patra AK, Muhammad K, Knobeloch K-P, Lichtinger M, Bonifer C, Wörtge S & Waisman A 2016 'NFATc1 releases BCL6-dependent repression of CCR2 agonist expression in peritoneal macrophages from Saccharomyces cerevisiae infected mice' European Journal of Immunology 46, (3) 634-646 , DOI
Chopra M, Langenhorst D, Beilhack A, Serfling E & Patra AK 2015 'Interleukin-2 critically regulates bone marrow erythropoiesis and prevents anemia development' European Journal of Immunology 45, (12) 3362-3374 , DOI
Muhammad K, Alrefai H, Marienfeld R, Pham DAT, Murti K, Patra AK, Avots A, Bukur V, Sahin U & Kondo E 2014 'NF-κB factors control the induction of NFATc1 in B lymphocytes' European Journal of Immunology 44, (11) 3392-3402 , DOI
Rudolf R, Busch R, Patra AK, Muhammad K, Avots A, Andrau J-C, Klein-Hessling S & Serfling E 2014 'Architecture and Expression of the Nfatc1 Gene in Lymphocytes' Frontiers in Immunology 5, , DOI PEARL
Hock M, Vaeth M, Rudolf R, Patra AK, Pham DAT, Muhammad K, Pusch T, Bopp T, Schmitt E & Rost R 2013 'NFATc1 Induction in Peripheral T and B Lymphocytes' The Journal of Immunology 190, (5) 2345-2353 , DOI
Patra AK, Avots A, Zahedi RP, Schüler T, Sickmann A, Bommhardt U & Serfling E 2012 'An alternative NFAT-activation pathway mediated by IL-7 is critical for early thymocyte development' Nature Immunology 14, (2) 127-135 , DOI
Bhattacharyya S, Deb J, Patra AK, Thuy Pham DA, Chen W, Vaeth M, Berberich-Siebelt F, Klein-Hessling S, Lamperti ED & Reifenberg K 2011 'NFATc1 affects mouse splenic B cell function by controlling the calcineurin–NFAT signaling network' The Journal of Experimental Medicine 208, (4) 823-839 , DOI PEARL
Patra AK, Drewes T, Engelmann S, Chuvpilo S, Kishi H, Hunig T, Serfling E & Bommhardt UH 2006 'PKB Rescues Calcineurin/NFAT-Induced Arrest of Rag Expression and Pre-T Cell Differentiation' The Journal of Immunology 177, (7) 4567-4576 , DOI
Patra AK, Na S-Y & Bommhardt U 2004 'Active Protein Kinase B Regulates TCR Responsiveness by Modulating Cytoplasmic-Nuclear Localization of NFAT and NF- B Proteins' The Journal of Immunology 172, (8) 4812-4820 , DOI
Patra AK 2003 'Constitutively active protein kinase B enhances Lck and Erk activities and influences thymocyte selection and activation' Journal of Immunology PEARL
Conference Papers
Kerstan A, Alrefai H, Muhammad K, Rudolf R, Pham DA, Klein-Hessling S, Patra AK, Avots A, Bukur V & Sahin U 2016 'NFATc1 promotes imiquimod-induced skin inflammation by negatively controlling IL-10 production in B cells' E26-E26
Patra AK, Avots A, Zahedi RP, Schueler T, Sickmann A, Bommhardt U & Serfling E 2013 'Interleukin-7-mediated NFAT activation sets the threshold for T cell development' 289-289 , DOI