Determining the effects of menopause on the oral microbiome and systemic health

Applications are invited for a three-year PhD studentship. The studentship will start on 1 October 2026.

Apply 

Due to funding restrictions, this studentship is only available to those candidates who meet the residency requirements for "Home" status.
To apply please use the online application form. Simply click on the online application link below for PhD Dental Studies
Within the research section of the application form, in the following field, please add: 
‘Proposed project title/studentship title’ add 26-01 PDS S1-P1 Wai Ling Kok.
When the application asks for a research proposal, please just upload a blank document. A research proposal is not needed for this programme as you are applying directly to a studentship project.

Application guidance 

It is important that you follow the instructions above or your application for this studentship may be missed and therefore will not be considered.
Before applying, please ensure you have read the Doctoral College’s general information on applying for a postgraduate research degree.
For more information on the admissions process please contact research.degree.admissions@plymouth.ac.uk.
Director of Studies (DoS): Dr Wai Ling Kok 
Applications are invited for a three-year PhD studentship. The studentship will start on 1 October 2026.

Project description 

Menopause is receiving increased scientific attention, including the oral microenvironment changes that occur with female ageing, which may be attributed to hormonal changes during menopause. The decline in oestrogen levels is associated with reduced salivary flow (dry mouth) and oral microbiome dysbiosis, which in turn increases the risk of dental caries and periodontal diseases. The aim of this project is to fully define changes in the oral microbiome during menopause in the context of oestrogen status and clinical oral health, followed by using a suitable preventative intervention to improve these outcomes.
The successful candidate will be trained to conduct a prospective observational and intervention clinical study, analysing metagenomics of the oral microbiome and performing various biochemical assays of the saliva and oral samples. The PhD will work closely with the dental team at the primary care dental clinics (PDSE), which is fully equipped for clinical trials research. They will gain experience and competency in conducting clinical research which will also have direct patient benefit. Therefore, this role is especially suitable for someone who is passionate about translational research and interested in the origin of hormone-driven microbial changes and potential therapeutic innovations in female ageing. It is not necessary to be a registered clinician, but the successful applicant must be highly professional and have strong communication skills, essential for recruitment, consenting and managing people with complex health conditions.  
If you wish to discuss this project further informally, please contact Dr Wai Ling Kok (wailing.kok@plymouth.ac.uk).

Eligibility

Applicants should have a first or upper second-class honours degree in an appropriate subject or a relevant Master’s qualification. 
Due to funding restrictions, this studentship is only available to those candidates who meet the residency requirements for "Home" status.
If your first language is not English, you will need to meet the minimum English requirements for the programme, IELTS Academic score of 6.5 (with no less than 5.5 in each component test area) or equivalent. 
The studentship is supported for 3 years and includes full Home tuition fees plus a stipend of £19,830 per annum 2026/27 rate. 
The studentship is supported for three years of the four-year registration period. The fourth year is a self-funded ‘writing-up’ year if the thesis extends beyond three years. 
Full-time jobs cannot be held alongside a full-time stipend.
How to apply
To apply, please click the ‘Online application’ link above. Please include the following documents with your application
  • CV / résumé
  • Personal Statement (outlining your academic interests, prior research experience and reasons for wishing to undertake the project).
  • Degree certificates and transcripts (please provide interim transcript if you are still studying). 
  • Contact information for two referees familiar with your academic work.
Please also see here for a list of supporting documents to upload with your application.
For more information on the admissions process generally, please visit our How to Apply for a Research Degree webpage or contact the Doctoral College.
The closing date for application is 30 June 2026. Shortlisted candidates will be invited for interview the week beginning 17 August. We regret that we may not be able to respond to all applications. Applicants who have not received a response within six weeks of the closing date should consider their application has been unsuccessful on this occasion.