Dr Tina Joshi
Profiles

Dr Tina Joshi

Lecturer in Molecular Microbiology

School of Biomedical Sciences (Faculty of Health)

Tina can be contacted through arrangement with our Press Office, to speak to the media on these areas of expertise.
  • Microbiology
  • Infectious disease
  • Molecular biology
  • Disinfection
  • Antibiotic resistance
  • Pathogens
  • Diagnostics
Biography

Biography

I am a Lecturer in Molecular Microbiology and Employability Coordinator within the School of Biomedical Sciences. I primarily teach Clinical Microbiology and Infectious Diseases across programmes within the School. My interdisciplinary research is focussed on Infection Prevention and Control and Molecular Pathogen Diagnostics (using novel technologies) to help tackle the Global Healthcare Challenge of AntiMicrobial Resistance (AMR). 

I am a recognised national expert in AntiMicrobial Resistance and my knowledge exchange and policy activities contribute to help policy makers and the wider public enhance their understanding of AMR. I am passionate about public engagement and I regularly provide expert commentary in the areas of Infectious Diseases, COVID19 transmission and AMR in local, national and international media.

Dr Joshi's professional YouTube Channel.

Lead for the Microbial Diagnostics and Infection Control Research Group.

Background: After obtaining my BSc in Microbiology in 2008 at Cardiff University, I completed my PhD in Molecular Microbiology and Biosensor Diagnostics at the Welsh School of Pharmacy, Cardiff University in 2012 and patented the findings. I subsequently undertook several multidisciplinary postdoctoral projects exploring commercial development and translation of these biosensor technologies in collaboration with microwave engineers at Cardiff School of Engineering and industry partners. I translated the technology to detect a wide range of clinical pathogens while gaining teaching experience. I joined the University of Plymouth in 2017 as a Lecturer in Molecular Microbiology where I have successfully built an independent research group and strong national and international collaborations focussing on Microbial Diagnostics for AMR and Infection Control. 

Awards:

In 2021 I was a Highly Commended Finalist for the 2021 Top 50 Women in Engineering: Engineering Heroes, Womens Engineering Society
In 2020 I was shortlisted as "Most Innovative Teacher of the Year" at the national Times Higher Education Awards (THE2020)
In 2019 I was nominated as an "Inspirational Woman in STEMM" at the regional Devon and Cornwall Venus Awards
In 2018 I was awarded the Hind Rattan "Jewel of India" Award from the Indian Government (Non-Resident Indian Welfare Society of India) for diasporal achievements in research and academia within the UK.

Qualifications

  • 2019: Postgraduate Certificate of Academic Practice with Distinction (PGCD)
  • 2019: Fellow of the Higher Education Academy
  • 2012: PhD Pharmacy "Pathogenicity and a bedside real-time detection assay for C. difficile in the faeces of hospitalised patients". Cardiff University
  • 2008: BSc Microbiology Hons. Cardiff University

Professional membership

Fellow of the Institute of Biomedical Sciences (FIBMS); Fellow Higher Education Academy (FHEA); Member of Royal Society of Biology (MRSB); Member of Society for Applied Microbiology; Member of Microbiology Society; Member of Antibiotic Research UK; Member of Healthcare Infection Society; Member of American Society for Microbiology, British Society for Antimicrobial Chemotherapy.

Roles on external bodies

External Committees

Microbiology Society:
 - Chair-Elect of Federation of Infection Societies (FIS) (National)
 - Impact and Influence Committee [Policy] (National)
 - AMR Advisory Group (National)
Antibiotic Research UK (ANTRUK): Science Committee (National)
Royal Society of BiologyDevon & Cornwall Branch Committee (Regional)

Internal Committees
University of Plymouth Public Engagement Champions Group
University of Plymouth Employability Advisory Group
Faculty of Health Early Career Researcher Group

Public Engagement:
SoapBox Science Plymouth Organiser (Annual)
Microbiology Society Champion- Plymouth

Journal Reviewer:
Journal of Applied Microbiology; Letters in Applied Microbiology; Applied & Environmental Microbiology (ASM); FEMS Microbiology Letters; BMC Microbiology; American Journal of Infection Control; Biosensors; Pathogens; Access Microbiology; Anaerobe; mSystems (ASM); Journal of Medical Microbiology.

Key publications

Jones IA & Joshi LT (2021) 'Biocide Use in the Antimicrobial Era: A Review' Molecules 26, (8) 2276-2276 , DOI Open access
Dyer C, Hutt LP, Burky R & Joshi LT (2019) 'Biocide Resistance and Transmission of Clostridium difficile Spores Spiked onto Clinical Surfaces from an American Health Care Facility' Applied and Environmental Microbiology , DOI Open access
Joshi LT, Mali BL, Geddes CD & Baillie L (2014) 'Extraction and Sensitive Detection of Toxins A and B from the Human Pathogen Clostridium difficile in 40 Seconds Using Microwave-Accelerated Metal-Enhanced Fluorescence' PLoS ONE 9, (8) e104334-e104334 , DOI Open access
View all publications
Teaching

Teaching

Teaching interests

I teach infectious diseases, clinical microbiology, molecular diagnosis of microbial infections, infection control and bacterial genomics at UG and PG level in the School of Biomedical Sciences. I achieved Fellowship of the Higher Education Academy in 2019 and the Post Graduate Certificate in Academic Practice with Distinction (PGCD). I encourage an open and relaxed learning environment where students feel able and comfortable to ask questions and enjoy learning.


Winner of "Inspirational Teaching Award" and "Most Effective Feedback" Awards for the Faculty of Health at the UPSU SSTAR awards in 2020.

Shortlisted as "Most Innovative Teacher of the Year" at The Times Higher Education (THE) Awards 2020.

Module Leader (Infection Sciences):
BHCS001 Infection, Immunity & Therapeutics
BHCS2006 Infection, Immunity & Disease
BHCS3003 Clinical Microbiology

Research Project Supervisor:
BIOM5006 MSc Biomedical Sciences Research Projects (Biosensor and Molecular Microbiology focused)
BHCS3021 Research Project in Healthcare Sciences
BHCS3001 Research Projects in Molecular Microbiology & Infection Control

Other Teaching Involvement:
BHCS1011 Study Skills and personal development
BHCS1006 Infection & Immunity
BHCS2001 Biology of Disease
BHCS2027 Placements & Employability
BHCS3031 Personal Development & Employability
BHCS3016 Public Health Infection Sciences (Biodefense and Clinical Bacteriology)
BHCS5008 Infection & Immunity

Research

Research

Research interests

Lead for the Microbial Diagnostics and Infection Control Research Group.

Rapid point of care detection of Antimicrobial Resistant (AMR) bacteria

Tina is an expert in the development of novel ultra-rapid point-of-care diagnostics for detection of infections (featured on BBC One's "The Truth about Antibiotics"). She is developing an international reputation of excellence within this area. Tina's wealth of multidisciplinary experience (<12 years) lies specifically in the areas of novel microwave-enhanced rapid diagnostics for microbial detection and DNA extraction, combined with the newest developments in molecular biology. She has honed these multidisciplinary skills during her Ph.D placement at the Institute of Fluorescence at the University of Maryland, Baltimore Country, USA with global experts in novel rapid diagnostics. Areas of expertise include: Clostridioides difficile, Bacillus anthracis; AMR pathogens; Field effect transistors, thin-film transistors, application of Microwave engineering to molecular biology, aptamer design, aptamer-functionalisation of nanoparticles, microwave-accelerated metal enhanced fluorescence, microbial bioinformatics and biosensor development. 

Infection Prevention and Control & Microbicides

Tina has a strong interest in infection control and this research looks to understand how biocide use can affect the genomic and phenotypic properties of viruses, bacteria and spores. A key theme is Clostridioides difficile spore persistence and transfer across fomites and clinical environments. Recently her research into Clostridium difficile spore resistance to chlorine and persistence on hospital gowns has made UK and international news. The paper has been published in Applied and Environmental Microbiology (2019). Areas of expertise: Category 2 and 3 pathogens, biocide testing, molecular microbiology, DNA sequencing, industry collaborations. Tina also provides expert consultancy in these areas.

Community Engagement

Tina is passionate about public engagement and knowledge mobilisation. To this end she is collaborating with local Plymouth charities to produce Infection Control and hygiene learning resources for adults with learning difficulties. She is also working with the School of Psychology to examine impacts and public opinions of AMR and COVID19.

Research degrees awarded to supervised students

Tina has successfully and independently supervised both undergraduate and postgraduate students. Applications for PhD research in Tina's areas of expertise are welcomed. Please email: tina.joshi@plymouth.ac.uk

Current PhD students (Director of Studies)
Alexandra Gartshore (2019-2022) The molecular effects of microwave irradiation upon antibiotic resistant bacterial pathogens

Current Group Members 
Katherine Silver - Research Assistant
Imogen Anne Jones - UG Placement student

Current PhD students (Co-Supervisor):
Justyna Lopatecka - Establishment and characterization of human alveolar macrophage like cell lines (Co-supervisor with Dr Gyuri Fejer

Current ResM students (Co-Supervisor):
Caitlin Pink (ResM Candidate - Co-supervisor with Professor Mathew Upton)
Sanduni Thanthi Hewage Peiris (ResM Candidate - Co-supervisor with Dr Gyuri Fejer)

Past Group Members:
Dianne Antonio (UG Student)
Shannon Waterfield (UG Student)
Nellie Dalpadoruge Fernando (UG Student)
Humaira Ahmed (UG student)

Grants & contracts

Tina is developing a strong track record in obtaining research funding. 

Recent funding includes:

Faculty of Health Pump-Prime Fund, University of Plymouth. Bacteriology & Neurobiology. April 2021- July 2021, Internal Competition. £8,500. Co- Investigator with Dr Konstantin Glebov (PI) & Prof Edgar Kramer

Finsen Technologies Ltd. Efficacy of UV-C technologies to decontaminate clinical environments. March 2021 - ongoing. £14,005. Principal Investigator.

R & D Solutions Fund, University of Plymouth. Efficacy of UV-C technologies to decontaminate PPE (Personal Protective Equipment) and surfaces from pathogenic microorganisms. February 2021- ongoing, Internal Competition. £15,805. Principal Investigator.

Higher Education Innovation Fund (HEIF), University of Plymouth. COVID19: Empowering Creativity & Community. January 2021- ongoing. Internal competition. £7994. Principal Investigator collaborating with Plymouth charity Well Connected, Millfields Inspired and iMayflower in Faculty of Arts and Humanities. 

Finsen Technologies Ltd. Efficacy of UVC technologies to decontaminate clinical gowns (PPE) and surfaces. October 2020 - ongoing. £12,500. Principal Investigator.

Royal Society of Biology Travel Grant. Clostridium difficile spore biology in hospital infection control research at Universidad de Andres Bello; Santiago, Chile. £500. May 2019 - September 2019. Principal Investigator. 

Harry Smith Vacation Studentship: Microbiology Society. Efficacy of point-of-care microwave technologies to release DNA from AMR microorganisms present in Urinary Tract infections. £1475. April 2019 - June 2019. Principal Investigator.

Research Impact & Innovation Fund, University of Plymouth. Exploring the Impact of a hand held ultra-rapid Point of Care diagnostic (5 minutes) which targets antibiotic resistance genes. Internal Competition. £17,500. July 2018 - June 2019. Principal Investigator.

Healthcare Infection Society (HIS) Travel Grant. HIS International Conference, Liverpool, November 2018. £750. Oral Presentation.

Dr. Robert Burky & Rideout Hospital, California, USA. Adherence of C. difficile spores to surgical gowns. £5943. May 2016 - June 2018. Principal Investigator.  

Society for Applied Microbiology Students into Work Grant. Persistence of antimicrobial resistant bacteria on Clinical isolation gowns. £2490. May 2018. Principal Investigator.

Previous Grants:

Welsh Government Life Sciences Bridging Fund, Cardiff University & Cotton Mouton Diagnostics. Rapid detection of Clostridioides difficile using magneto-optical diagnostics. £50,000. April 2016- March 2017. Co-Investigator.

Wellcome Trust ISSF & Cardiff University.  Rapid microwave-enhanced detection of Clostridium difficile. £69,356. June 2014 - July 2015. Co-Investigator with Cardiff School of Engineering.

EPSRC Impact Acceleration Award & Cardiff University. Rapid microwave-enhanced detection of Clostridium difficile. £48,000. June 2013 - June 2014. Co-Investigator with Cardiff School of Engineering.

Publications

Publications

Key publications

Jones IA & Joshi LT (2021) 'Biocide Use in the Antimicrobial Era: A Review' Molecules 26, (8) 2276-2276 , DOI Open access
Dyer C, Hutt LP, Burky R & Joshi LT (2019) 'Biocide Resistance and Transmission of Clostridium difficile Spores Spiked onto Clinical Surfaces from an American Health Care Facility' Applied and Environmental Microbiology , DOI Open access
Joshi LT, Mali BL, Geddes CD & Baillie L (2014) 'Extraction and Sensitive Detection of Toxins A and B from the Human Pathogen Clostridium difficile in 40 Seconds Using Microwave-Accelerated Metal-Enhanced Fluorescence' PLoS ONE 9, (8) e104334-e104334 , DOI Open access

Key publications are highlighted

Journals
Articles
Jones IA & Joshi LT (2021) 'Biocide Use in the Antimicrobial Era: A Review' Molecules 26, (8) 2276-2276 , DOI Open access
Gartshore A, Kidd M & Joshi LT (2021) 'Applications of Microwave Energy in Medicine' Biosensors 11, (4) 96-96 , DOI Open access
McKracken M, Garner C & Joshi LT (2020) 'COVID-19 and antibiotic resistance – The calm before the storm' AMRC Open Research , DOI Open access
Dyer C, Hutt LP, Burky R & Joshi LT (2019) 'Biocide Resistance and Transmission of Clostridium difficile Spores Spiked onto Clinical Surfaces from an American Health Care Facility' Applied and Environmental Microbiology , DOI Open access
Joshi LT, Welsch A, Hawkins J & Baillie L (2017) 'The effect of hospital biocide sodium dichloroisocyanurate on the viability and properties of Clostridium difficile spores' Lett Appl Microbiol 65, (3) 199-205 Author Site , DOI Open access
Imtiaz A, Lees J, Choi H & Joshi LT (2015) 'An Integrated Continuous Class-${\rm F} ^{-1}$ Mode Power Amplifier Design Approach for Microwave Enhanced Portable Diagnostic Applications' IEEE Transactions on Microwave Theory and Techniques 63, (10) 3007-3015 , DOI Open access
Joshi LT, Mali BL, Geddes CD & Baillie L (2014) 'Extraction and Sensitive Detection of Toxins A and B from the Human Pathogen Clostridium difficile in 40 Seconds Using Microwave-Accelerated Metal-Enhanced Fluorescence' PLoS ONE 9, (8) e104334-e104334 , DOI Open access
Joshi LT, Phillips DS, Williams CF, Alyousef A & Baillie L (2012) 'Contribution of Spores to the Ability of Clostridium difficile To Adhere to Surfaces' Applied and Environmental Microbiology 78, (21) 7671-7679 , DOI Open access
Drevinek P, Baldwin A, Lindenburg L, Joshi LT, Marchbank A, Vosahlikova S, Dowson CG & Mahenthiralingam E (2010) 'Oxidative Stress of Burkholderia cenocepacia Induces Insertion Sequence-Mediated Genomic Rearrangements That Interfere with Macrorestriction-Based Genotyping' Journal of Clinical Microbiology 48, (1) 34-40 , DOI Open access
Posters
Waterfield S, Hutt L, Burky R & Joshi LT Waterfield S, Hutt L, Burky R & Joshi LT 'Isolation and characterization of Clostridioides difficile spores from contaminated single-used surgical gowns' , DOI Open access
Personal

Personal

Reports & invited lectures

“Rise of Superbugs & COVID19” – Plymouth Probus Group. May 2020.

"Development of rapid diagnostics for infections" at University of Surrey Exploiting the Potential of Rapid Diagnostic Test Technology and Mobile Connectivity conference, 29 - 30 May 2019. 

"Rise of Superbugs" at Swansea University, Institute of Life Science, November 2019.

"Rise of Superbugs" at Plymouth Athenaeum, Plymouth October 2019.

"Antibiotic Resistance: Tackling an emerging problem". British Society of Dental Hygiene & Therapy South West. March 2019.

“Antimicrobial Resistance: Why is it important?” Invited Expert Panel Member, London School of Hygiene and Tropical Medicine, Oct 2018.

"Science and the Assembly- Antimicrobial Resistance". Invited Expert Panel. Detection of Antimicrobial Resistance. Now and the Future. National Assembly of Wales, Royal Society of Chemistry, June 2017.

Conferences organised

Soapbox Science Plymouth - Yearly (Organising Committee)

Other academic activities

Media & Public Engagement:

I have strong engagement with Media in promoting understanding of Antimicrobial Resistance and understanding of COVID19. This includes newspaper articles, blogs, online social media, radio and national television. 

I regularly provide expert commentary on BBC Spotlight, BBC Radio Devon and BBC Radio Cornwall.


Reports:

A Sustainable Future- Antimicrobial Resistance Policy Report” 2020 Microbiology Society (AMR Advisory Group contributor)

Patents Granted:

Baillie, L & Joshi L.T. EP2847348B1 A screening method for the detection of Clostridium difficile.

Additional information

I am a strong advocate for promoting STEM with the aim of encouraging interest in studying these subjects. 
I am part of "Inspiring the Future" and am a STEM Ambassador. I continue to mentor students with their prospective scientific career choices and am heavily involved in varying Women in Science mentorship schemes. I am interested in advancing equality across HE, specifically with regard to Race Equality (Race Equality Charter) and Gender Equality through the Athena Swan Charter at the University of Plymouth. I also work with Charity Well Connected to promote general hygiene and antibiotic awareness.

Links

PLymouth ANtimicrobial EngagemenT (PLANET) Initiative: Highlighting the issue of antimicrobial and antibiotic resistance