Dr Rob Clough

Biography

I manage the Analytical Research Facility and also the SoGEES ISO 9001 quality management system.

I train users in advanced analytical instrumentation, such as inductively coupled plasma mass spectrometry and inductively coupled plasma optical emission spectrometry and associated sample preparation techniques.

Qualifications

2000-2003, PhD in Analytical Chemistry with Drs Hywel Evans and Simon Belt, University of Plymouth.

1997-2000, BSc (hons) Environmental Science, University of Plymouth.

Professional membership

Member Royal Society Chemistry

Roles on external bodies

Chair, Atomic Spectrometry Updates Editorial Board

Treasurer, Western Region Analytical Division, Royal Society of Chemistry

Teaching

Teaching interests

My teaching is mainly practical based and covers several areas including analytical chemistry, environmental analytical chemistry, high accuracy analysis, advanced analytical instrumentation, data quality, chemical metrology and quality management systems at the undergraduate and postgraduate level for B.Sc. Chemistry, MChem,B.Sc.Environmental Science and MSc Environmental Geochemistry.

Research

Research interests

My main research area is analytical chemistry with a particular focus on three areas:

Chemical metrology, ensuring that analytical results are valid and fit for purpose with a current focus on micronutrients, such as Fe, in the open ocean.

Nanoparticle extraction from various matrices and measurements using single particle inductively coupled plasma mass spectrometry.

Elemental Speciation, the coupling of high performance liquid chromatography to inductively coupled plasma mass spectrometry with a focus on arsenic bioaccessibility.

Creative practice & artistic projects

Was once a backing drinker.

Publications

Key publications

Key publications are highlighted

Journals

Articles

Clough R, Harrington CF, Hill SJ, Madrid Y & Tyson JF (2023) 'Atomic spectrometry update: review of advances in elemental speciation' Journal of Analytical Atomic Spectrometry 38, (7) 1339-1371 , DOI

Clough R, Harrington CF, Hill SJ, Madrid Y & Tyson JF (2022) 'Atomic Spectrometry Update: review of advances in elemental speciation' Journal of Analytical Atomic Spectrometry 37, (7) 1387-1430 , DOI Open access

Carter S, Clough R, Fisher A, Gibson B & Russell B (2022) 'Atomic spectrometry update: review of advances in the analysis of metals, chemicals and materials' Journal of Analytical Atomic Spectrometry 37, (11) 2207-2281 , DOI Open access

Laycock A, Clark NJ, Clough R, Smith R & Handy RD (2022) 'Determination of metallic nanoparticles in biological samples by single particle ICP-MS: a systematic review from sample collection to analysis' Environmental Science: Nano , DOI Open access

Clough R, Harrington CF, Hill SJ, Madrid Y & Tyson JF (2021) 'Atomic Spectrometry Update: review of advances in elemental speciation' Journal of Analytical Atomic Spectrometry 36, (7) 1326-1373 , DOI Open access

Carter S, Clough R, Fisher A, Gibson B & Russell B (2021) 'Atomic spectrometry update: review of advances in the analysis of metals, chemicals and materials' Journal of Analytical Atomic Spectrometry 36, (11) 2241-2305 , DOI Open access

Clark NJ, Clough R, Boyle D & Handy RD (2021) 'Quantification of particulate Ag in rainbow trout organs following dietary exposure to silver nitrate, or two forms of engineered silver nanoparticles' Environmental Science: Nano , DOI Open access

Dhanda A, Atkinson S, Vergis N, Enki D, Fisher A, Clough R, Cramp M & Thursz M (2020) 'Trace element deficiency is highly prevalent and associated with infection and mortality in patients with alcoholic hepatitis' Alimentary Pharmacology & Therapeutics , DOI Open access

Hill S & Clough R (2020) 'Atomic spectrometry update: review of advances in elemental speciation' JAAS , DOI Open access

Tokalioglu S, Clough R, Foulkes M & Worsfold P (2020) 'Stability of Arsenic Species During Bioaccessibility Assessment Using the In Vitro UBM and HPLC-ICP-MS Detection' Biological Trace Element Research 198, (1) 332-338 , DOI Open access

Clough R, Harrington CF, Hill SJ, Madrid Y & Tyson JF (2020) 'Atomic spectrometry update: review of advances in elemental speciation' Journal of Analytical Atomic Spectrometry 35, (7) 1236-1278 , DOI Open access

Carter S, Clough R, Fisher A, Gibson B, Russell B & Waack J (2020) 'Atomic spectrometry update: review of advances in the analysis of metals, chemicals and materials' Journal of Analytical Atomic Spectrometry 35, (11) 2410-2474 , DOI Open access

Clough R, Lohan MC, Ussher SJ, Nimmo M & Worsfold PJ (2019) 'Uncertainty associated with the leaching of aerosol filters for the determination of metals in aerosol particulate matter using collision/reaction cell ICP-MS detection' Talanta 199, 425-430 , DOI Open access

Worsfold P, Achterberg E, Birchill A, Clough R, Leito I, Lohan M, Milne A & Ussher S (2019) 'Estimating Uncertainties in Oceanographic Trace Element Measurements' Frontiers in Marine Science , DOI Open access

Clough R, Harrington CF, Hill SJ, Madrid Y & Tyson JF (2019) 'Atomic spectrometry update: review of advances in elemental speciation' Journal of Analytical Atomic Spectrometry 34, (7) 1306-1350 , DOI Open access

Carter S, Clough R, Fisher A, Gibson B, Russell B & Waack J (2019) 'Atomic spectrometry update: review of advances in the analysis of metals, chemicals and materials' Journal of Analytical Atomic Spectrometry 34, (11) 2159-2216 , DOI Open access

Clark NJ, Clough R, Boyle D & Handy RD (2019) 'Development of a suitable detection method for silver nanoparticles in fish tissue using single particle ICP-MS' Environmental Science: Nano 6, (11) 3388-3400 , DOI Open access

Clough R, Harrington CF, Hill SJ, Madrid Y & Tyson JF (2018) 'Atomic Spectrometry Update: review of advances in elemental speciation' Journal of Analytical Atomic Spectrometry 33, (7) 1103-1149 , DOI Open access

Carter S, Clough R, Fisher A, Gibson B, Russell B & Waack J (2018) 'Atomic spectrometry update: review of advances in the analysis of metals, chemicals and materials' Journal of Analytical Atomic Spectrometry 33, (11) 1802-1848 , DOI Open access

Clough R, Harrington CF, Hill SJ, Madrid Y & Tyson JF (2017) 'Atomic spectrometry update: review of advances in elemental speciation' Journal of Analytical Atomic Spectrometry 32, (7) 1239-1282 , DOI Open access

Browne MA, Brooks PR, Clough R, Fisher AS, Mayer Pinto M & Crowe TP (2016) 'Simulating regimes of chemical disturbance and testing impacts in the ecosystem using a novel programmable dosing system' Methods in Ecology and Evolution 7, (5) 609-618 , DOI Open access

Clough R, Harrington CF, Hill SJ, Madrid Y & Tyson JF (2016) 'Atomic Spectrometry Update: review of advances in elemental speciation' Journal of Analytical Atomic Spectrometry 31, (7) 1330-1373 , DOI Open access

Butler OT, Clough R, Cook JM, Evans EH, Fisher AS, Hill SJ, Taylor A & West M (2016) 'Current trends: a perspective from 30 years of Atomic Spectrometry Updates' Journal of Analytical Atomic Spectrometry 31, (1) 32-34 , DOI

Clough R, Floor GH, Quétel CR, Milne A, Lohan MC & Worsfold PJ (2016) 'Measurement uncertainty associated with shipboard sample collection and filtration for the determination of the concentration of iron in seawater' Anal. Methods 8, (37) 6711-6719 , DOI Open access

Floor GH, Clough R, Lohan MC, Ussher SJ, Worsfold PJ & Quetel CR (2015) 'Combined uncertainty estimation for the determination of the dissolved iron amount content in seawater using flow injection with chemiluminescence detection' LIMNOLOGY AND OCEANOGRAPHY-METHODS 13, (12) 673-686 Author Site , DOI Open access

Harrington CF, Clough R, Hill SJ, Madrid Y & Tyson JF (2015) 'Atomic Spectrometry Update: review of advances in elemental speciation' JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY 30, (7) 1427-1468 Author Site , DOI

Clough R, Sela H, Milne A, Lohan MC, Tokalioglu S & Worsfold PJ (2014) 'Uncertainty contributions to the measurement of dissolved Co, Fe, Pb and V in seawater using flow injection with solid phase preconcentration and detection by collision/reaction cell-quadrupole ICP-MS' Talanta 133, 162-169 Author Site , DOI Open access

Clough R, Harrington CF, Hill SJ, Madrid Y & Tyson JF (2014) 'Atomic spectrometry updates. Review of advances in elemental speciation' JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY 29, (7) 1158-1196 Author Site , DOI Open access

Tokalioglu S, Clough R, Foulkes M & Worsfold P (2013) 'Bioaccessibility of Cr, Cu, Fe, Mg, Mn, Mo, Se and Zn from nutritional supplements by the unified BARGE method' Food Chem 150, 321-327 Author Site , DOI Open access

Worsfold PJ, Clough R, Lohan MC, Monbet P, Ellis PS, Quétel CR, Floor GH & McKelvie ID (2013) 'Flow injection analysis as a tool for enhancing oceanographic nutrient measurements--a review' Anal Chim Acta 803, 15-40 Author Site , DOI

Clough R, Harrington CF, Hill SJ, Madrid Y & Tyson JF (2013) 'Atomic spectrometry update. Elemental speciation review' JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY 28, (8) 1153-1195 Author Site , DOI

Clough R, Drennan-Harris LR, Harrington CF, Hill SJ & Tyson JF (2012) 'Atomic spectrometry update. Elemental speciation' JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY 27, (8) 1185-1224 Author Site , DOI

Scarlett AG, Clough R, West CE, Lewis CA, Booth AM & Rowland SJ (2011) 'Alkylnaphthalenes: priority pollutants or minor contributors to the poor health of marine communities?' Environmental Science and Technology 45, (14) 6160-6166 , DOI

Harrington CF, Clough R, Drennan-Harris LR, Hill SJ & Tyson JF (2011) 'Atomic spectrometry update. Elemental speciation' JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY 26, (8) 1561-1595 Author Site , DOI

Rider SA, Davies SJ, Jha AN, Clough R & Sweetman JW (2010) 'Bioavailability of co-supplemented organic and inorganic zinc and selenium sources in a white fishmeal-based rainbow trout (Oncorhynchus mykiss) diet' J Anim Physiol Anim Nutr (Berl) 94, (1) 99-110 Author Site , DOI

Harrington CF, Clough R, Hansen HR, Hill SJ & Tyson JF (2010) 'Atomic spectrometry update. Elemental speciation' JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY 25, (8) 1185-1216 Author Site , DOI

Dissanayake A, Clough R, Spicer JI & Jones MB (2010) 'Effects of hypercapnia on acid-base balance and osmo-/iono-regulation in prawns (Decapoda: Palaemonidae)' AQUATIC BIOLOGY 11, (1) 27-36 Author Site , DOI

Marshall WA, Clough R & Gehrels WR (2009) 'The isotopic record of atmospheric lead fall-out on an Icelandic salt marsh since AD 50' Sci Total Environ 407, (8) 2734-2748 Author Site , DOI

Harrington CF, Clough R, Hansen HR, Hill SJ, Pergantis SA & Tyson JF (2009) 'Atomic Spectrometry Update. Elemental speciation' JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY 24, (8) 999-1025 Author Site , DOI

Clough R, Evans P, Catterick T & Evans EH (2006) 'Delta34S measurements of sulfur by multicollector inductively coupled plasma mass spectrometry' Anal Chem 78, (17) 6126-6132 Author Site , DOI

Clough R, Belt ST, Fairman B, Catterick T & Evans EH (2005) 'Uncertainty contributions to single and double isotope dilution mass spectrometry with HPLC-CV-MC-ICP-MS for the determination of methylmercury in fish tissue' Journal of Analytical Atomic Spectrometry 20, (10) 1072-1075

Clough R, Truscatt J, Belt ST, Evans EH, Fairman B & Catterick T (2003) 'Isotope dilution ICP-MS for speciation studies' Applied Spectroscopy Reviews 38, (1) 101-132

Clough R, Belt ST, Evans EH, Sutton P, Fairman B & Catterick T (2003) 'Uncertainty contributions to species specific isotope dilution analysis. Part 1. Characterisation and stability of Hg-199 and C-13 isotopically enriched methylmercury by H-1 NMR' Journal of Analytical Atomic Spectrometry 18, (9) 1033-1038

Clough R, Belt ST, Evans EH, Fairman B & Catterick T (2003) 'Uncertainty contributions to species specific isotope dilution analysis. Part 2. Determination of methylmercury by HPLC coupled with quadrupole and multicollector ICP-MS' Journal of Analytical Atomic Spectrometry 18, (9) 1039-1046

Clough R, Belt ST, Evans EH, Fairman B & Catterick T (2003) 'Investigation of equilibration and uncertainty contributions for the determination of inorganic mercury and methylmercury by isotope dilution inductively coupled plasma mass spectrometry' Analytica Chimica Acta 500, (1-2) 155-170

Letters

Rowland SJ, Clough R, West CE, Scarlett AG, Jones D & Thompson S (2011) 'Synthesis and mass spectrometry of some tri- and tetracyclic naphthenic acids' Rapid Communications in Mass Spectrometry 25, 2573-2578

Chapters

Evans EH & Clough R (2005) 'ISOTOPE DILUTION ANALYSIS' Encyclopedia of Analytical Science Elsevier 545-553 , DOI

Other Publications

Wu B, Wiekenkamp I, Sun Y, Fisher AS, Clough R, Gottselig N, Bogena H, Pütz T, Brüggemann N & Vereecken H A Dataset for Three-Dimensional Distribution of 39 Elements Including Plant Nutrients and Other Metals and Metalloids in the Soils of a Forested Headwater Catchment. Open access

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