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Dr Matt Banton

Research Fellow

School of Biomedical Sciences (Faculty of Health)



2020 - Research Fellow in Bioinformatics

Previous Roles

2012 - Post-doctoral Research associate (University of Cambridge) in the molecular characterisation of rare genetic variants associated with obesity.

2010 - Post-doctoral Research associate (University of Cambridge) on the intracellular trafficking of the inhibitory T-cell receptor, CTLA-4.


MPhil in Computational Biology (University of Cambridge).

PhD in Molecular Biology (University of Cambridge).

BSc (Hons) in Molecular Biology (University of Sheffield).



Teaching interests

I am interested in all aspects of Molecular Biology and Bioinformatics especially on the biological mechanisms that lead to disease. I teach on various modules including on the MSc Biomedical Science and BSc Biomedical Sciences. I also supervise 3rd year Bioinformatics research projects.



Research interests

I have a strong background in molecular and cell biology in the Biomedical sciences and became interested in bioinformatics while working as a Post-doc. I therefore decided to do a masters in Computational Biology to develop my bioinformatics skills. Since joining the University of Plymouth I have worked in collaboration with several groups based in the School of Biomedical Sciences and the Peninsula Medical School on various themes including cancer, peripheral nerve cell profiling by single cell RNA-seq, vaccine development and infection and immunity.

I am keen to collaborate on different projects with various groups, if you would like to discuss future bioinformatics projects with me or how I might be able to help with current projects please do get in touch.



Key publications

Key publications are highlighted

Li M, Min Q, Banton MC & Dun X (2021) 'Single-Cell Regulatory Network Inference and Clustering Identifies Cell-Type Specific Expression Pattern of Transcription Factors in Mouse Sciatic Nerve' Frontiers in Cellular Neuroscience 15, , DOI Open access
Li M, Banton MC, Min Q, Parkinson DB & Dun X (2021) 'Meta-Analysis Reveals Transcription Factor Upregulation in Cells of Injured Mouse Sciatic Nerve' Frontiers in Cellular Neuroscience 15, , DOI Open access
Chen B, Banton MC, Singh L, Parkinson DB & Dun X-P (2021) 'Single Cell Transcriptome Data Analysis Defines the Heterogeneity of Peripheral Nerve Cells in Homeostasis and Regeneration' Frontiers in Cellular Neuroscience 15, , DOI Open access
Yang Y, van der Klaauw AA, Zhu L, Cacciottolo TM, He Y, Stadler LKJ, Wang C, Xu P, Saito K & Hinton A (2019) 'Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis' Nature Communications 10, (1) , DOI Open access
van der Klaauw AA, Croizier S, Mendes de Oliveira E, Stadler LKJ, Park S, Kong Y, Banton MC, Tandon P, Hendricks AE & Keogh JM (2019) 'Human Semaphorin 3 Variants Link Melanocortin Circuit Development and Energy Balance' Cell 176, (4) 729-742.e18 , DOI Open access
Banton MC, Inder KL, Valk E, Rudd CE & Schneider H (2014) 'Rab8 Binding to Immune Cell-Specific Adaptor LAX Facilitates Formation of <i>trans</i> -Golgi Network-Proximal CTLA-4 Vesicles for Surface Expression' Molecular and Cellular Biology 34, (8) 1486-1499 , DOI Open access
Pearce LR, Atanassova N, Banton MC, Bottomley B, van der Klaauw AA, Revelli J-P, Hendricks A, Keogh JM, Henning E & Doree D (2013) 'KSR2 Mutations Are Associated with Obesity, Insulin Resistance, and Impaired Cellular Fuel Oxidation' Cell 155, (4) 765-777 , DOI
Banton MC & Tunnacliffe A (2012) 'MAPK phosphorylation is implicated in the adaptation to desiccation stress in nematodes' Journal of Experimental Biology , DOI
Huang Z, Banton MC & Tunnacliffe A (2010) 'Modeling anhydrobiosis: activation of the mitogen-activated protein kinase ERK by dehydration in both human cells and nematodes' Journal of Experimental Zoology Part A: Ecological Genetics and Physiology 313A, (10) 660-670 , DOI
Reardon W, Chakrabortee S, Pereira TC, Tyson T, Banton MC, Dolan KM, Culleton BA, Wise MJ, Burnell AM & Tunnacliffe A (2010) 'Expression profiling and cross-species RNA interference (RNAi) of desiccation-induced transcripts in the anhydrobiotic nematode Aphelenchus avenae' BMC Molecular Biology 11, (1) , DOI Open access
Presentations and posters
Akther Y, Adams C, Sharma V, Barros C, Banton M & Hanemann O Akther Y, Adams C, Sharma V, Barros C, Banton M & Hanemann O 'Proteomic analysis of genetically stratified low-grade meningioma' , DOI