no image available
Profiles

Dr Matt Banton

Research Fellow

School of Biomedical Sciences (Faculty of Health)

2020 - Research Fellow in Bioinformatics

Previous Roles

2012 - Post-doctoral Research associate (University of Cambridge) in the molecular characterisation of rare genetic variants associated with obesity.

2010 - Post-doctoral Research associate (University of Cambridge) on the intracellular trafficking of the inhibitory T-cell receptor, CTLA-4.

Qualifications

MPhil in Computational Biology (University of Cambridge).

PhD in Molecular Biology (University of Cambridge).

BSc (Hons) in Molecular Biology (University of Sheffield).

Teaching interests

I am interested in all aspects of Molecular Biology and Bioinformatics especially on the biological mechanisms that lead to disease. I have recently joined the School of Biomedical Science and will be teaching on various modules including on the MSc Biomedical Science.

Research interests

I have a strong background in Molecular and Cell biology in the Biomedical sciences and became interested in Bioinformatics while working as a Post-doc. I therefore decided to do a Masters in Computational Biology to develop my Bioinformatics skills and have been working on several Bioinformatics projects since, including on single cell RNA-seq. 

I am keen to collaborate on different projects with various groups, if you would like to discuss future projects with me or how I might be able to help with current projects please do get in touch.

Key publications

Key publications are highlighted

Journals
Articles
Chen B, Banton MC, Singh L, Parkinson DB & Dun X-P 2021 'Single Cell Transcriptome Data Analysis Defines the Heterogeneity of Peripheral Nerve Cells in Homeostasis and Regeneration' Frontiers in Cellular Neuroscience 15, , DOI Open access
Yang Y, van der Klaauw AA, Zhu L, Cacciottolo TM, He Y, Stadler LKJ, Wang C, Xu P, Saito K & Hinton A 2019 'Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis' Nature Communications 10, (1) , DOI Open access
van der Klaauw AA, Croizier S, Mendes de Oliveira E, Stadler LKJ, Park S, Kong Y, Banton MC, Tandon P, Hendricks AE & Keogh JM 2019 'Human Semaphorin 3 Variants Link Melanocortin Circuit Development and Energy Balance' Cell 176, (4) 729-742.e18 , DOI Open access
Banton MC, Inder KL, Valk E, Rudd CE & Schneider H 2014 'Rab8 Binding to Immune Cell-Specific Adaptor LAX Facilitates Formation of trans-Golgi Network-Proximal CTLA-4 Vesicles for Surface Expression' Molecular and Cellular Biology 34, (8) 1486-1499 , DOI Open access
Pearce LR, Atanassova N, Banton MC, Bottomley B, van der Klaauw AA, Revelli J-P, Hendricks A, Keogh JM, Henning E & Doree D 2013 'KSR2 Mutations Are Associated with Obesity, Insulin Resistance, and Impaired Cellular Fuel Oxidation' Cell 155, (4) 765-777 , DOI
Banton MC & Tunnacliffe A 2012 'MAPK phosphorylation is implicated in the adaptation to desiccation stress in nematodes' Journal of Experimental Biology 215, (24) 4288-4298 , DOI
Huang Z, Banton MC & Tunnacliffe A 2010 'Modeling anhydrobiosis: activation of the mitogen-activated protein kinase ERK by dehydration in both human cells and nematodes' Journal of Experimental Zoology Part A: Ecological Genetics and Physiology 313A, (10) 660-670 , DOI
Reardon W, Chakrabortee S, Pereira T, Tyson T, Banton MC, Dolan KM, Culleton BA, Wise MJ, Burnell AM & Tunnacliffe A 2010 'Expression profiling and cross-species RNA interference (RNAi) of desiccation-induced transcripts in the anhydrobiotic nematode Aphelenchus avenae' BMC Molecular Biology 11, (1) 6-6 , DOI Open access