Dr Manuela Truebano

Dr Manuela Truebano

Lecturer in Marine Molecular Biology

School of Biological and Marine Sciences (Faculty of Science and Engineering)



I am a lecturer in Marine Biology and member of the Ecophysiology and Development Research group, in the Marine Biology and Ecology Research Centre. I graduated in BSc Marine Biology at the University of Liverpool, before completing a Masters degree in Shellfish Biology at Bangor University, and a PhD in Molecular Ecophysiology (thermal stress) at the British Antarctic Survey and Swansea University.

I teach across undergraduate and postgraduate Marine Biology programmes.


  • 2014. PG Cert Academic Practice, University of Plymouth.
  • 2010. PhD. Swansea University & British Antarctic Survey.
  • 2005. MSc Shellfish Biology, Fisheries and Culture. Bangor University.
  • 2003. BSc Hons. Marine Biology. University of Liverpool

Professional membership

  • Fellow of the Higher Education Academy (since 2015)
  • Member of:
    • Genetics Society
    • Cell Stress Society International
    • Society of Experimental Biology

Roles on external bodies

  • Senior editor: Cell Stress and Chaperones (official journal of the Cell Stress Society International, Springer-Nature)



Teaching interests

  • Marine Molecular Biology (module leader)
  • Ecophysiology of Marine Animals (module leader) 
  • Conservation Physiology 
  • Marine Biology field courses (module leader of stage 2 Experimental Marine Biology field course)
  • Truebano M. & C. Munn. 2015. An Evaluation of the Use of Video Tutorials as Supporting Tools for Teaching Laboratory Skills in Biology. Practice and Evidence of Scholarship of Teaching and Learning in Higher Education 10(2):121-135.

2015. SoMSE. Technology enhanced learning: Video tutorials as part of a blended approach to teaching practical skills. PI.



Research interests

I am a marine biologist with a broad interest in ecophysiology and evolution. My research integrates whole organismal physiology and -omic approaches to investigate the mechanisms underpinning physiological responses to changes in environmental drivers, mainly temperature and oxygen, over different timescales. Much of my research is therefore framed under the context of global climate change and addresses whether aquatic animals have the capacity to cope with and adapt to the current rapid changes in their environment.

Current postdoctoral researchers:

Current PhD students:

  • Caitlin McAndry (DoS) "Adapting to climate change: transgenerational acclimation as a mechanism of rapid evolution"
  • Ahmed Abbas (DoS) "The challenge of securing future food production for aquaculture species: maternal, developmental and adaptational responses to multistressors"
  • Chris Dwane (DoS) “Assessing the vulnerability of aquatic invertebrates to climate change”
  •  Ziad Ibbini (2nd supervisor) "Assessing Sensitivity to Fluctuating Temperatures in Marine Animals"
  • Eleanor Gilbert (2nd supervisor) "Characterising the function of the apical organ in the early diverging metazoan Nematostella vectensis"
  • Ali Noth (4th supervisor)  "Mitigating the impacts of climate change, emerging disease and invasive species on native amphibian populations in the UK"
  • Ellis Moloney (3rd supervisor) "Extremophiles in a changing world: the mechanistic bases of stress resistance in rotifers and tardigrades"

Other research

I have supervised >60 undergraduate and masters students. Examples of project supervision include the following topics:

  • Transgenerational plasticity and its role in responding to environmental change
  • Responses to thermal stress over different time scales
  • Ontogeny of the cellular stress response
  • Thermal adaptation across intertidal gradients
  • Mechanisms of cross-tolerance between stressors
  • Environmental factors influencing hybrid zone dynamics
  • The role of parental and developmental environments in transgenerational plasticity
  • Thermal adaptation across latitudes
  • Molecular mechanisms underpinning responses to moderate and severe stress

Research degrees awarded to supervised students

  • Michael Collins, PhD (2019). "Effect on temperature on hypoxia thresholds in aquatic invertebrates" 
  • George Mason, ResM (2021). "The role of environmental temperature in immunocompetence and disease susceptibility in bivalves"

Grants & contracts

 2021. A Pack Atmosphere Support System for Live Crabs/Shellfish Species During Road Transported and Air-freighted Distribution.  Centre for Environment, Fisheries and Aquaculture Science.  PI (contract).

2020.  Adapting to climate change: transgenerational acclimation as a mechanism of rapid evolution.  ARIES Doctoral Training Partnership. PI.  

2020. Understanding the function of the apical organ in early branching metazoans.  ARIES Doctoral Training Partnership. Co-PI. 

2019. Is fine-scale, local adaptation linked to thermal stress physiology? A test using insitu transplant experiments. Association of European Marine Biological Laboratories Transnational Access Fund. Co-PI.

2019.  Mitigating the effects of climate change, emerging disease and invasive species on native amphibian populations in the UK.  ARIES Doctoral Training Partnership. Co-PI

2018. Epigenetic control of developmental robustness via endoplasmic reticulum chaperones.  Royal Society.  IEC\R3\170091.  PI. 

2015.  The role of additive and non-additive genetic effects during animal contests in the beadlet sea anemone Actinia equina.  Biotechnology and Biological Sciences Research Council. BB/M019772/1. Co-PI. 

2014.  The effect of in situ acclimatization to chronic hypoxia on the metabolome of the commercially important shrimp Pandalus borealis. Natural Environment Research Council. NBAF867. PI.

2013.  Transcriptome analysis of developmental stages in the amphipod Gammarus chevreuxi.  Natural Environment Research Council. NBAF622. Co- PI

2013. The Effect of in situ Acclimatization to Hypoxia on the Physiological and Molecular Plasticity of the Commercially Important Shrimp Pandalus borealis. Association of European Marine Biological Laboratories Transnational Access Fund. PI.



Key publications

Key publications are highlighted



Dwane C, Rezende EL, Tills O, Galindo J, Rolán-Alvarez E, Rundle S & Truebano M (2022) 'Thermodynamic effects drive countergradient responses in the thermal performance of Littorina saxatilis across latitude' Science of The Total Environment 863, 160877-160877 , DOI Open access
Tills O, Holmes LA, Quinn E, Everett T, Truebano M & Spicer JI (2022) 'Phenomics enables measurement of complex responses of developing animals to global environmental drivers' Science of the Total Environment , DOI Open access
Ibbini Z, Spicer JI, Truebano M, Bishop J & Tills O (2022) 'HeartCV: a tool for transferrable, automated measurement of heart rate and heart rate variability in transparent animals' Journal of Experimental Biology 225, (19) , DOI Open access
Collins M, Truebano M & Spicer JI (2022) 'Consequences of thermal plasticity for hypoxic performance in coastal amphipods' Marine Environmental Research 177, , DOI Open access
McAndry C, Collins M, Tills O, Spicer JI & Truebano M (2022) 'Regulation of gene expression during ontogeny of physiological function in the brackishwater amphipod Gammarus chevreuxi' Marine Genomics 63, , DOI Open access
Dwane C, Rundle SD, Tills O, Rezende EL, Galindo J, Rolán-Alvarez E & Truebano M (2021) 'Divergence in Thermal Physiology Could Contribute to Vertical Segregation in Intertidal Ecotypes of Littorina saxatilis' Physiological and Biochemical Zoology 94, (6) 353-365 , DOI Open access
Collins M, Truebano M, Verberk WCEP & Spicer JI (2021) 'Do aquatic ectotherms perform better under hypoxia after warm acclimation?' The Journal of Experimental Biology 224, (3) jeb232512-jeb232512 Publisher Site , DOI Open access
Collins M, Clark MS, Spicer JI & Truebano M (2020) 'Transcriptional frontloading contributes to cross‐tolerance between stressors' Evolutionary Applications , DOI Open access
Lane SM, Briffa M, Wilson AJ, Truebano M & Foster NL (2020) 'Evidence of fostering in an internally brooding sea anemone' Ethology 126, (12) 1141-1147 , DOI Open access
Truebano M, Robertson SD, Houston SJS & Spicer JI (2020) 'Ontogeny of osmoregulation in the brackishwater amphipod Gammarus chevreuxi' Journal of Experimental Marine Biology and Ecology 524, 151312-151312 , DOI Open access
Tolman D, Wood HL, Skibinski DOF & Truebano M (2019) 'Differential immunity as a factor influencing mussel hybrid zone structure' Marine Biology 166, (12) , DOI Open access
Collins M, Tills O, Turner LM, Clark MS, Spicer JI & Truebano M (2019) 'Moderate reductions in dissolved oxygen may compromise performance in an ecologically-important estuarine invertebrate' Science of the Total Environment 693, 133444-133444 , DOI Open access
Tills O, Truebano M, Feldmeyer B, Pfenninger M, Morgenroth H, Schell T & Rundle SD (2018) 'Transcriptomic responses to predator kairomones in embryos of the aquatic snail Radix balthica' Ecology and Evolution 8, (22) 11071-11082 Author Site , DOI Open access
Truebano M, Fenner P, Tills O, Rundle SD & Rezende EL (2018) 'Thermal strategies vary with life history stage' Journal of Experimental Biology 221, (Pt 8) Author Site , DOI Open access
Truebano M, Tills O, Collins M, Clarke C, Shipsides E, Wheatley C & Spicer JI (2018) 'Short-term acclimation in adults does not predict offspring acclimation potential to hypoxia' Scientific Reports 8, (1) 0-0 , DOI Open access
Schell T, Feldmeyer B, Schmidt H, Greshake B, Tills O, Truebano M, Rundle SD, Paule J, Ebersberger I & Pfenninger M (2017) 'An Annotated Draft Genome for Radix auricularia (Gastropoda, Mollusca)' Genome Biology and Evolution 9, (3) 585-592 , DOI Open access
Collins M, Tills O, Spicer JI & Truebano M (2017) 'De novo transcriptome assembly of the amphipod Gammarus chevreuxi exposed to chronic hypoxia' Marine Genomics 33, 17-19 , DOI Open access
Truebano M, Tills O & Spicer JI (2016) 'Embryonic transcriptome of the brackishwater amphipod Gammarus chevreuxi' Marine Genomics 28, 5-6 , DOI
Tills O, Truebano M & Rundle S (2015) 'An embryonic transcriptome of the pulmonate snail Radix balthica' Marine Genomics 24, 259-260 , DOI
Obermüller BE, Truebano M, Peck LS, Eastman JT & Morley SA (2013) 'Reduced seasonality in elemental CHN composition of Antarctic marine benthic predators and scavengers' Journal of Experimental Marine Biology and Ecology 446, 328-333 , DOI
Truebano M, Diz AP, Thorne MAS, Clark MS & Skibinski DOF (2013) 'Proteome response to heat stress in the Antarctic clam Laternula elliptica' Journal of Integrated OMICS 3, (1) , DOI
Calosi P, Turner LM, Hawkins M, Bertolini C, Nightingale G, Truebano M & Spicer JI (2013) 'Multiple Physiological Responses to Multiple Environmental Challenges: An Individual Approach' Integrative and Comparative Biology 53, (4) 660-670 , DOI
Clark MS, Husmann G, Thorne MAS, Burns G, Truebano M, Peck LS, Abele D & Philipp EER (2013) 'Hypoxia impacts large adults first: consequences in a warming world' Global Change Biology 19, (7) 2251-2263 , DOI
Truebano M, Burns G, Thorne MAS, Hillyard G, Peck LS, Skibinski DOF & Clark MS (2010) 'Transcriptional response to heat stress in the Antarctic bivalve Laternula elliptica' Journal of Experimental Marine Biology and Ecology 391, (1-2) 65-72 , DOI
Diz AP, Truebano M & Skibinski DOF (2009) 'The consequences of sample pooling in proteomics: An empirical study' ELECTROPHORESIS 30, (17) 2967-2975 , DOI
Beaumont A, Truebano Garcia M, Hönig S & Low P (2006) 'Genetics of Scottish populations of the native oyster,<i>Ostrea edulis</i>: gene flow, human intervention and conservation' Aquatic Living Resources 19, (4) 389-402 , DOI
Spicer JI, Tills OA, Truebano M & Rundle SD (2018) 'Developmental Plasticity and Heterokairy' in Burggren W; Dubanksy B Development and Environment , DOI
Conference Papers
Calosi P, Turner LM, Hawkins M, Nightingale G, Bertolini C, Truebano-Garcia M, Ford A & Spicer JI (2013) 'The effect of exposure to multiple environmental challenges on multiple physiological responses: an inter-individual approach' E28-E28


Reports & invited lectures

  • Responses to environmental stress across timescales: an ecophysiology approach. British Ecological Society Aquatic Ecology group meeting, September 2021.

Conferences organised

  • Session in International Conference. Technology enabled approaches in ecophysiology. Society of Experimental Biology. 29 June-8 July, virtual conference. 
  • Session in International Conference. The ecology-physiology-life-history nexus: integrating ecophysiology in evolving life history syndromes. BES/NECOV/GFO/EEF joint annual meeting: Ecology across borders. 11-14 December 2017, Ghent, Belgium.
  • Session in International Conference. Change and aquatic life: effects of multiple drivers, from molecules to ecosystems. Society of Experimental Biology Conference. 3-6 July 2017. Gothenburg, Sweden.