Profiles
Dr Liyam Laraba
Research Fellow
Peninsula Medical School (Faculty of Health)
Biography
Biography
I am an early-career researcher in neuro-oncology with a focus on NF2-deficient tumours of the nervous system.
Since completing my undergraduate and master's degree in biochemistry at the University of Birmingham, I came to the lab of Prof David Parkinson at the University of Plymouth for my PhD.
I am now developing as an independent researcher within NF2-related tumour biology whilst developing broader interests such as teaching.
Qualifications
MSc Biochemistry - University of Birmingham, 2016.
PhD Neuro-oncology - University of Plymouth, 2021.
Research
Research
Research interests
I am interested in the role of dysregulated Hippo signalling in NF2-null tumours of the nervous system.
We use both primary human meningioma and schwannoma cell cultures as well as relevant mouse models to test drugs which target aberrant tumour cell activity.
Grants & contracts
Children's Tumor Foundation Young Investigator Award - 2020-2022
Publications
Publications
Key publications
Key publications are highlighted
Journals
· Marta Palomo-Irigoyen,1 Encarni Pérez-Andrés,1 Marta Iruarrizaga-Lejarreta,1 Adrián Barreira-Manrique,1 Miguel Tamayo-Caro,1 Laura Vila-Vecilla,1 Leire Moreno-Cugnon,1 Nagore Beitia,1 Daniela Medrano,1 David Fernández-Ramos,1,2 Juan José Lozano,3 Satoshi Okawa,4,5 José L. Lavín,1 Natalia Martín-Martín,1,6 James D. Sutherland,1 Virginia Guitiérez de Juan,1,2 Monika Gonzalez-Lopez,1 Nuria Macías-Cámara,1,2 David Mosén-Ansorena,1 Liyam Laraba,7 C. Oliver Hanemann,7 Emanuela Ercolano,7 David B. Parkinson,7 Christopher W. Schultz,8 Marcos J. Araúzo-Bravo,9,10 Alex M. Ascensión,9 Daniela Gerovska,9 Haizea Iribar,11 Ander Izeta,11 Peter Pytel,12 Philipp Krastel,13 Alessandro Provenzani,14 Pierfausto Seneci,15 Ruben D. Carrasco,16 Antonio Del Sol,1,4,10,17 María Luz Martinez-Chantar,1,2 Rosa Barrio,1 Eduard Serra,6,18 Conxi Lazaro,6,19,20 Adrienne M. Flanagan,21,22 Myriam Gorospe,23 Nancy Ratner,24 Ana M. Aransay,1,2 Arkaitz Carracedo,1,6,10,25 Marta Varela-Rey,1,2 and Ashwin Woodhoo1,10. (2020) HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis. J Clin Invest. 2020;130(7): 3848-3864. https://doi.org/10.1172/JCI130379.
· Emmanuel A. Maze2†, Bora Agit1†, Shona Reeves1, David A. Hilton1, David B. Parkinson1, Liyam Laraba1, Emanuela Ercolano1, Kathreena M. Kurian4, C. Oliver Hanemann1+, Robert Belshaw 2,3+* and Sylwia Ammoun1+* Human Endogenous Retrovirus Type K promotes proliferation of Merlin-negative schwannoma and meningioma which can be inhibited by anti-retroviral and anti-TEAD drugs. Cancer Res. 2021; accepted, online ahead of print. https://doi.org/10.1158/0008-5472.CAN-20-3857
Personal
Personal
Other academic activities
· Children’s Tumour Foundation Meeting – November 2018
Poster Presentation.
· British Neuropathological Society – March 2019
Oral presentation.
· Berlin Brain Tumour Meeting – May 2019
Poster Presentation.
· AACR Virtual meeting – March 2020
Poster Presentation.
· Children’s Tumour Foundation Virtual Meeting – June 2021
Oral Presentation.