- Open Aera, Davy Building, Drake Circus, Plymouth, PL4 8AA
- +44 1752 584593
- lee.hutt@plymouth.ac.uk

Profiles
Dr Lee Hutt
Lecturer in Biomedical Sciences
School of Biomedical Sciences (Faculty of Health)
Biography
Biography
Lecturer in Biomedical Sciences
Qualifications
Teaching
Teaching
Teaching interests
Module Leader:
BHCS002 Current Developments in Human Biology and Biomedical Sciences
Teaching Involvement:
FMD001 Molecules to Cells
BHCS001 Infection, Immunity and Therapeutics
BHCS1003 Human Metabolism
BHCS1004 Introduction to Human Pathology
BHCS1005 Human Disease
BHCS1006 Infection and Immunity
BHCS2004 Cell Biology in Health and Disease
BHCS2006 Infection, Immunity and Disease
BHCS3003 Clinical Microbiology
BIOM5003 Contemporary Science of Infection and Immunity
BIOM5005 Project Design and Development
BHCS5010 Contemporary Applications in Cancer Biology and Therapeutics
Research
Research
Research interests
Biodiversity and anti-microbial potential of the Roman Baths, Bath
It is estimated that as many as 10 million people a year will die due to anti-microbial resistance (AMR) and cost the global economy 100 trillion US dollars per year by 2050. In order to tackle this threat scientists have started looking into novel compounds with anti-microbial activity from more "unusual" environments. The Roman Baths (Bath) is the only ‘warm’ hot spring in the UK and is rich in microbiological diversity, several species of which I worked on during my Ph.D. I am conducting research into both the microbial diversity of the Roman Baths and attempting to isolate bacterial strains producing novel compounds with anti-microbial activity.
Biology and Novel Treatments for eukaryotic parasites
Intestinal parasites, such as Giardia intestinalis, infect millions of people globally every year. The World Health Organisation (WHO) considers Giardiasis (the disease caused be Giardia) as one of the World's most neglected diseases, with approximately 1 billion people in developing parts of the world at risk of infection every year. The disease is relatively easy to treat with common types of antibiotics; however, there is increasing evidence of anti-microbial resistance (AMR) in this parasite. I am interested in identifying novel therapeutics/prophylactic treatments for Giardiasis and mechanisms by which Giardia becomes resistant to anti-microbials. Understanding the biology of this unusual Eukaryote organism is key to our treatment of the disease it causes.
Please contact me if you wish to discuss my areas of research further.Publications
Publications
Hutt, L. P., Harper, G. M., Moody, A. J. & Boden, R. (2020) Insights into growth kinetics and roles of enzymes of Krebs’ cycle and sulfur oxidation during exochemolithoheterotrophic growth of Achromobacter aegrifaciens NCCB 38021 on succinate with thiosulfate as the auxiliary electron donor. Archives of Microbiology, https://doi.org/10.1007/s00203-020-02028-1.
Dyer, C., Hutt, L. P., Burky, R. & Joshi, L. T. (2019) Biocide resistance and transmission of Clostridium difficile spores spiked onto clinical surfaces from an American healthcare facility. Applied and Environmental Microbiology, 85 (17) doi: 10.1128/AEM.01090-19.
Boden, R. & Hutt, L. P. (2019) Acidithiobacillus. In: Bergey’s Manual of Systematics of Archaea and Bacteria. John Wiley & Sons, Inc.
Boden, R. & Hutt, L. P. (2019) Annwoodia. In: Bergey’s Manual of Systematics of Archaea and Bacteria. John Wiley & Sons, Inc.
Boden, R. & Hutt, L. P. (2019) Hydrogenophilalia. In: Bergey’s Manual of Systematics of Archaea and Bacteria. John Wiley & Sons, Inc.
Boden, R. & Hutt, L. P. (2019) Thermithiobacillus. In: Bergey’s Manual of Systematics of Archaea and Bacteria. John Wiley & Sons, Inc.
Boden, R. & Hutt, L. P. (2019) Thiobacillus. In: Bergey’s Manual of Systematics of Archaea and Bacteria. John Wiley & Sons, Inc.
Boden, R. & Hutt, L. P. (2018) Aerobic Bacterial Catabolism of Dimethylsulfoniopropionate. In: Rojo F (Ed) Aerobic utilization of hydrocarbon and lipid microbiology. Cham, Switzerland: Springer. 1-27.
Boden, R. & Hutt, L. P. (2018) Bacterial Metabolism of C1 Sulfur Compounds. In: Rojo F (Ed) Aerobic utilization of hydrocarbon and lipid microbiology. Cham, Switzerland: Springer. 1-43.
Boden, R. & Hutt, L. P. (2018) Determination of kinetic parameters and metabolic modes using the chemostat. In: Consequences of microbial interactions with hydrocarbons, oils, and lipids: Biodegradation and bioremediation. Cham, Switzerland: Springer. 1-42.
Boden, R. & Hutt, L. P. (2018) Chemolithoheterotrophy: Means to higher growth yields from this widespread metabolic trait. In: Rojo F (Ed) Aerobic utilization of hydrocarbon and lipid microbiology. Cham, Switzerland: Springer. 1-25.