Dr Holly Roy

Dr Holly Roy

Honorary University Fellow

Faculty of Health


Academic clinical fellow in neurosurgery



Research interests

My research is based in David Parkinson's group. One of the main aims of the group is to characterise the factors which drive the regenerative capacity of the peripheral nervous system. The focus of my project is investigating the role of the Hippo signalling pathway on gene expression in Schwann cells following injury.

Key publications are highlighted


1.  The Central Autonomic Network and Regulation of Bladder Function. Roy HA, Green AL. Frontiers in Autonomic Neuroscience (in press)

2.  Investigation of lower urinary tract symptoms in Parkinson’s disease utilising structural MRI techniques. Roy HA, Griffiths DJ, Aziz TZ, Green AL, Menke RAL. Neurourology & Urodynamics 2019; 38 (4): 1168-1175

3.  Thalamic deep brain stimulation relieves breathlessness in COPD. Green AL, Debrah E, Roy HA, Moosavi SH. Brain stimulation 2019; 12 (3):827-828

4.  The pedunculopontine region and breathing in Parkinson’s disease. Hyam J, Wang S, Roy HA, Moosavi SH, Martin S, Brittain JS, Coyne T, Silburn P, Aziz TZ Annals of Clinical and Translational Neurology (in press)

5.  Understanding cauda equina syndrome: protocol for a UK multicentre prospective observational study: protocol for a UK multicentre prospective observational study. Woodfield J, Hoeritzauer I, Jamjoom AAB, Pronin S, Srikandarajah N, Poon M, Roy H, Demetriades AK, Sell P, Eames N, Statham, PFX & British Neurosurgical Research Collaborative. BMJ Open 2018; 8 (12): e025230

6.  Neuromodulation for Pelvic and Urogenital Pain. Roy H, Offiah I & Dua A. Brain Sci 2018; 8(10): 180

7.  Beta Oscillations and Urinary Voiding in Parkinson’s Disease. Roy HA, Aziz TZ, FitzGerald JJ, Green AL. Neurology 2018 24;90:e1530-1534

8.  The management of traumatic brain injury. Roy HA, Richards PGR. Paediatrics and child health

9.  Effects of Pedunculopontine Nucleus Stimulation on Human Bladder Function. Roy HA, Roy C, Pond D, Forrow B, Zrinzo L, Foltynie T, Akram H, Fitzgerald JJ, Aziz TZ, Green AL. Neurourology and urodynamics 2017 Jun 12. doi: 10.1002/nau.23321.

10. State of the art: novel applications for deep brain stimulation. Roy HA, Green AL, Aziz TZ. Neuromodulation. 2017 May 17. doi: 10.1111/ner.12604

11. Deep brain stimulation and multiple sclerosis: Therapeutic applications. Roy HA, Aziz TZ. Multiple sclerosis and related disorders (2014) 3: 431-439

12. Sub-aponeurotic fluid collection in a neonate associated with fetal scalp electrode monitoring: a brief communication. Roy HA, Magdum S. Eur J Obstet Gynaecol Reprod Biol 2014; 181: 343-4

13. Dyspnoea as a side effect of subthalamic nucleus deep brain stimulation for Parkinson’s disease. Chalif JI, Sitsapesan HA, Pattinson KTS, Herigstad M, Aziz TZ, Green AL. Respiratory Physiology and Neurobiology 2014; 192:128-33

14. Deep brain stimulation for tremor resulting from acquired brain injury. Sitsapesan HA, Holland P, Oliphant Z, De Pennington N, Brittain JS, Jenkinson N, Joint C, Aziz TZ, Green AL. Journal of Neurology, Neurosurgery and Psychiatry 2014; 85(7):811-5

15. The periaqueductal grey area and control of blood pressure in neurodegeneration. Sitsapesan HAGreen AL, Aziz TZ, Pereira EAC. Clin Auton Res 2013;23: 215-219

16. Neurotrauma outside the high income setting: a review of audit and data collection strategies. Sitsapesan HA, Lawrence TP, Sweasey C, Wester K. World Neurosurg 2013; 79:568-75

17. The Management of Traumatic Brain Injury. Sitsapesan HA, Richards PGR. Paediatrics and Child Health

18. Idiopathic Normal Pressure Hydrocephalus: An Important Differential Diagnosis. Paranathala M, Sitsapesan HA, Green AL, Cadoux-Hudson T & Pereira EA. British Journal of Hospital Medicine 2013; 74:564-70

19. Switching off micturition using deep brain stimulation at midbrain sites. Green AL, Stone E, Sitsapesan HA, Turney BW, Coote JH, Aziz TZ, Hyam JA, Lovick TA. Ann Neurol 2012; 72:144-7

20. Effect of volatile anaesthetics on the calcium release channel in the heart. Laver DR, Quail T, Sitsapesan H, van Helden DF. Biophysical Journal 2009; 96: 113a