Articles
Dun X-P, Carr L, Woodley PK, Barry RW, Drake LK, Mindos T, Roberts SL, Lloyd AC & Parkinson DB (2023) 'Retraction Notice to: Macrophage-Derived Slit3 Controls Cell Migration and Axon Pathfinding in the Peripheral Nerve Bridge' Cell Reports 42, (5) 112517-112517 ,
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Laraba L, Hillson L, de Guibert JG, Hewitt A, Jaques MR, Tang TT, Post L, Ercolano E, Rai G & Yang SM (2022) 'Inhibition of YAP/TAZ-driven TEAD activity prevents growth of NF2-null schwannoma and meningioma' Brain ,
DOI Open access
Parkinson D (2022) 'Inhibition of YAP/TAZ-driven TEAD activity prevents growth of NF2-null schwannoma and meningioma' Brain ,
DOI Open access
Maze EA, Agit B, Reeves S, Hilton DA, Parkinson DB, Laraba L, Ercolano E, Kurian KM, Hanemann CO & Belshaw RD (2021) 'Human endogenous retrovirus type K promotes proliferation and confers sensitivity to anti-retroviral drugs in Merlin-negative schwannoma and meningioma' Cancer Research ,
DOI Open access
Li M, Banton MC, Min Q, Parkinson DB & Dun X (2021) 'Meta-Analysis Reveals Transcription Factor Upregulation in Cells of Injured Mouse Sciatic Nerve' Frontiers in Cellular Neuroscience 15, ,
DOI Open access
Chen B, Banton MC, Singh L, Parkinson DB & Dun X-P (2021) 'Single Cell Transcriptome Data Analysis Defines the Heterogeneity of Peripheral Nerve Cells in Homeostasis and Regeneration' Frontiers in Cellular Neuroscience 15, ,
DOI Open access
Rafipay A, Dun X, Parkinson DB, Erskine L & Vargesson N (2021) 'Knockdown of slit signaling during limb development leads to a reduction in humerus length' Developmental Dynamics 250, (9) 1340-1357 ,
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Chen B, Hu R, Min Q, Li Y, Parkinson DB & Dun X-P (2020) 'FGF5 Regulates Schwann Cell Migration and Adhesion' Frontiers in Cellular Neuroscience 14, ,
DOI Open access
Min Q, Parkinson DB & Dun X (2020) 'Migrating Schwann cells direct axon regeneration within the peripheral nerve bridge' Glia ,
DOI Open access
Palomo-Irigoyen M, Pérez-Andrés E, Iruarrizaga-Lejarreta M, Barreira-Manrique A, Tamayo-Caro M, Vila-Vecilla L, Moreno-Cugnon L, Beitia N, Medrano D & Fernández-Ramos D (2020) 'HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis' Journal of Clinical Investigation 130, (7) 3848-3864 ,
DOI Open access
Dun X (2019) 'Distinct VIP and PACAP Functions in the Distal Nerve Stump During Peripheral Nerve Regeneration' Frontiers in Neuroscience ,
DOI Open access
Chen B, Chen Q, Parkinson DB & Dun X-P (2019) 'Analysis of Schwann Cell Migration and Axon Regeneration Following Nerve Injury in the Sciatic Nerve Bridge' Frontiers in Molecular Neuroscience 12, ,
DOI Open access
Dun X-P & Parkinson D (2019) 'Classic axon guidance molecules control correct nerve bridge tissue formation and precise axon regeneration' Neural Regeneration Research 15, (1) 6-6 ,
DOI Open access
Dun X, Carr L, Woodley P, Barry R, Drake L, Mindos T, Robert S, Lloyd A & Parkinson D (2019) 'Macrophage-Derived Slit3 Controls Cell Migration and Axon Pathfinding in the Peripheral Nerve Bridge' Cell Reports 26, (6) ,
DOI Open access
Roberts SL, Dun X-P, Doddrell RDS, Mindos T, Drake LK, Onaitis MW, Florio F, Quattrini A, Lloyd AC & D'Antonio M (2017) 'Sox2 expression in Schwann cells inhibits myelination <i>in vivo</i> and induces influx of macrophages to the nerve' Journal of Cell Science 130, (18) e1.2-e1.2 ,
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Dun X-P & Parkinson D (2017) 'Role of Netrin-1 Signaling in Nerve Regeneration' International Journal of Molecular Sciences 18, (3) 491-491 ,
DOI Open access
Carr L, Parkinson DB & Dun X-P (2017) 'Expression patterns of Slit and Robo family members in adult mouse spinal cord and peripheral nervous system' PLoS One 12, (2) e0172736-e0172736 Author Site ,
DOI Open access
Mindos T, Dun X-P, North K, Doddrell RDS, Schulz A, Edwards P, Russell J, Gray B, Roberts SL & Shivane A (2017) 'Merlin controls the repair capacity of Schwann cells after injury by regulating Hippo/YAP activity' Journal of Cell Biology 495-510 ,
DOI Open access
Mindos T, Dun X-P, North K, Schulz A, Gray B, Pan D, Edwards P, Shivane A, Morrison H & Parkinson D (2017) 'The Merlin tumour suppressor controls the repair capacity of Schwann cells following injury by regulating Hippo pathway signalling' Journal of Cell Biology 65, E40-E41 ,
DOI Open access
Roberts SL, Dun X-P, Dee G, Gray B, Mindos T & Parkinson DB (2017) 'The role of p38alpha in Schwann cells in regulating peripheral nerve myelination and repair' Journal of Neurochemistry ,
DOI Open access
Roberts SL, Dun X-P, Doddrell RDS, Mindos T, Drake LK, Onaitis MW, Florio F, Quattrini A, D'Antonio M & Parkinson DB (2017) 'Sox2 expression in Schwann cells inhibits myelination in vivo and induces influx of macrophages to the nerve' Development Author Site ,
DOI Open access
Schulz A, Büttner R, Hagel C, Baader SL, Kluwe L, Salamon J, Mautner VF, Mindos T, Parkinson DB & Gehlhausen JR (2016) 'The importance of nerve microenvironment for schwannoma development' Acta neuropathologica ,
DOI Open access
Dun X-P & Parkinson DB (2015) 'Visualizing peripheral nerve regeneration by whole mount staining' PLoS One 10, (3) Author Site ,
DOI Open access
Plotkin SR, Albers AC, Babovic-Vuksanovic D, Blakeley JO, Breakefield XO, Dunn CM, Evans DG, Fisher MJ, Friedman JM & Giovannini M (2014) 'Update from the 2013 International Neurofibromatosis Conference' AMERICAN JOURNAL OF MEDICAL GENETICS PART A 164, (12) 2969-2978 Author Site ,
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Kim HA, Mindos T & Parkinson DB (2013) 'Plastic Fantastic: Schwann Cells and Repair of the Peripheral Nervous System' STEM CELLS TRANSLATIONAL MEDICINE 2, (8) 553-557 Author Site ,
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Schulz A, Baader SL, Niwa-Kawakita M, Jung MJ, Bauer R, Garcia C, Zoch A, Schacke S, Hagel C & Mautner V-F (2013) 'Merlin isoform 2 in neurofibromatosis type 2-associated polyneuropathy' NATURE NEUROSCIENCE 16, (4) 426-U86 Author Site ,
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Shivane A, Parkinson DB, Ammoun S & Hanemann CO (2013) 'Expression of c-Jun and Sox-2 in human schwannomas and traumatic neuromas' HISTOPATHOLOGY 62, (4) 651-656 Author Site ,
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Doddrell RDS, Dun X-P, Shivane A, Feltri ML, Wrabetz L, Wegner M, Sock E, Hanemann CO & Parkinson DB (2013) 'Loss of SOX10 function contributes to the phenotype of human Merlin-null schwannoma cells' Brain 136, (Pt 2) 549-563 Author Site ,
DOI Open access
Doddrell RDS, Dun X-P, Moate RM, Jessen KR, Mirsky R & Parkinson DB (2012) 'Regulation of Schwann cell differentiation and proliferation by the Pax-3 transcription factor' GLIA 60, (9) 1269-1278 Author Site ,
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Yang DP, Kim J, Syed N, Tung YJ, Bhaskaran A, Mindos TC, Mirsky R, Jessen KR, Maurel P & Parkinson DB (2012) 'p38 MAPK activation promotes denervated Schwann cell phenotype and functions as a negative regulator of Schwann cell differentiation and myelination' The Journal of Neuroscience 32(21), 7158-7168
Yang DP, Kim J, Syed N, Tung Y-J, Bhaskaran A, Mindos T, Mirsky R, Jessen KR, Maurel P & Parkinson DB (2012) 'p38 MAPK activation promotes denervated Schwann cell phenotype and functions as a negative regulator of Schwann cell differentiation and myelination' J Neurosci 32, (21) 7158-7168 Author Site ,
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Arthur-Farraj P, Wanek K, Hantke J, Davis CM, Jayakar A, Parkinson DB, Mirsky R & Jessen KR (2011) 'Mouse schwann cells need both NRG1 and cyclic AMP to myelinate' Glia 59, (5) 720-733 Author Site ,
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Mustafa MK, Nabok A, Parkinson D, Tothill IE, Salam F & Tsargorodskaya A (2010) 'Detection of β-amyloid peptide (1–16) and amyloid precursor protein (APP770) using spectroscopic ellipsometry and QCM techniques: A step forward towards Alzheimers disease diagnostics' Biosensors and Bioelectronics 26, (4) 1332-1336 ,
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Parrinello S, Napoli I, Ribeiro S, Wingfield Digby P, Fedorova M, Parkinson DB, Doddrell RDS, Nakayama M, Adams RH & Lloyd AC (2010) 'EphB signaling directs peripheral nerve regeneration through Sox2-dependent Schwann cell sorting' Cell 143, (1) 145-155 Author Site ,
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Whiteman M, Li L, Rose P, Tan C-H, Parkinson DB & Moore PK (2010) 'The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages' Antioxid Redox Signal 12, (10) 1147-1154 Author Site ,
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Woodhoo A, Alonso MBD, Droggiti A, Turmaine M, D'Antonio M, Parkinson DB, Wilton DK, Al-Shawi R, Simons P & Shen J (2009) 'Notch controls embryonic Schwann cell differentiation, postnatal myelination and adult plasticity' Nat Neurosci 12, (7) 839-847 Author Site ,
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Mirsky R, Woodhoo A, Parkinson DB, Arthur-Farraj P, Bhaskaran A & Jessen KR (2008) 'Novel signals controlling embryonic Schwann cell development, myelination and dedifferentiation' J Peripher Nerv Syst 13, (2) 122-135 Author Site ,
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Parkinson DB, Bhaskaran A, Arthur-Farraj P, Noon LA, Woodhoo A, Lloyd AC, Feltri ML, Wrabetz L, Behrens A & Mirsky R (2008) 'c-Jun is a negative regulator of myelination' J Cell Biol 181, (4) 625-637 Author Site ,
DOI Open access
Flaiz C, Utermark T, Parkinson DB, Poetsch A & Hanemann CO (2008) 'Impaired intercellular adhesion and immature adherens junctions in merlin-deficient human primary schwannoma cells' Glia 56, (5) 506-515 Author Site ,
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Parkinson D, Bhaskaran A, rthur-Farraj P, Noon L, Lloyd A, Behrens A, Feltri L, Wrabetz L, Mirsky R & Lessen K (2007) 'A central role for c-Jun in regulating the differentiation of Schwann cells' Neuron Glia Biology 2, S38-S38
Parkinson D, Bhaskaran A, Arthur-Farraj P, Noon L, Lloyd A, Behrens A, Feltri L, Wrabetz L, Mirsky R & Lessen K (2007) 'A central role for c-Jun in regulating the differentiation of Schwann cells' NEURON GLIA BIOLOGY 2, S38-S38 Author Site
Mirsky R, Woodhoo A, Parkinson DB, Banerjee A, Sharghi-Namini S & Jessen KR (2007) 'GBS/CIDP foundation international lecture - Signals that control Schwann cell development and myelination' Journal of the Peripheral Nervous System 12, 2-2
Hossain S, Parkinson DB, Mushynski WE & Almazan G (2007) 'Mitogen Activated Protein Kinase p38 regulates transcription factor Krox-20 and Schwann cell differentiation' NEURON GLIA BIOLOGY 2, S138-S139 Author Site
Hossain S, Parkinson DB, Mushynski WE & Almazan G (2007) 'Mitogen Activated Protein Kinase p38 regulates transcription factor Krox-20 and Schwann cell differentiation' Neuron Glia Biology 2, S138-S139
Bhaskaran A, Parkinson D, Mirsky R & Jessen KR (2007) 'Schwann cell myelination is inhibited by c-jun and p38 mitogen activated protein kinase pathways' NEURON GLIA BIOLOGY 2, S42-S42 Author Site
Bhaskaran A, Parkinson D, Mirsky R & Jessen KR (2007) 'Schwann cell myelination is inhibited by c-jun and p38 mitogen activated protein kinase pathways' Neuron Glia Biology 2, S42-S42
Arthur-Farraj P, Bhaskaran A, Parkinson D, Turmaine M, Feltri L, Wrabetz L, Behrens A, Mirsky R & Lessen K (2007) 'The transcription factor c-Jun, controls Schwann cell demyelination and dedifferentiation after peripheral nerve injury' NEURON GLIA BIOLOGY 2, S133-S133 Author Site
rthur-Farraj P, Bhaskaran A, Parkinson D, Turmaine M, Feltri L, Wrabetz L, Behrens A, Mirsky R & Lessen K (2007) 'The transcription factor c-Jun, controls Schwann cell demyelination and dedifferentiation after peripheral nerve injury' Neuron Glia Biology 2, S133-S133
Newton JRA, Parkinson D & Clench MR (2006) 'Strategies for examination of Alzheimer’s disease amyloid precursor protein isoforms' Analytical and Bioanalytical Chemistry 385, (4) 692-699 ,
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Parkinson D, Arthur-Farraj P, Jessen K & Mirsky R (2006) 'A double point mutation in the DNA-binding region of Egr2 switches its function from inhibition to induction of proliferation: A potential contribution to the development of congenital hypomyelinating neuropathy' Neurobiology of Disease 24, (1) 159-169 ,
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Parkinson (2006) 'A double point mutation in the DNA-binding region of Egr2 switches its function from inhibition to induction of proliferation: A potential contribution to the development of congenital hypomyelinating neuropathy' Neurobiology of Disease 24 (1), 159-69 ,
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Parkinson DB, Bhaskaran A, Mirsky R & Jessen KR (2005) 'Krox-20 inhibits the Jun-n-terminal kinase/C-Jun pathway to regulate the myelinating phenotype of Schwann cells' Journal of Neurochemistry 94, 139-139
Jessen KR, Mirsky R, Woodhoo A, Parkinson D & Bhaskaran A (2005) 'The function of Notch and stress kinase signals in early Schwann cell development' Journal of Neurochemistry 94, 2-2
Harrisingh MC, Perez-Nadales E, Parkinson DB, Malcolm DS, Mudge AW & Lloyd AC (2004) 'The Ras/Raf/ERK signalling pathway drives Schwann cell dedifferentiation' EMBO J 23, (15) 3061-3071 Author Site ,
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Parkinson D, Bhaskaran A, Dickinson S & Droggiti A (2004) 'Krox-20 inhibits Jun-NH2-terminal kinase/c-Jun to control Schwann cell proliferation and death' The Journal of Cell Biology 164, (3) 385-394 ,
DOI Open access
Parkinson DB, Bhaskaran A, Droggiti A, Dickinson S, D'Antonio M, Mirsky R & Jessen KR (2004) 'Krox-20 inhibits Jun-NH2-terminal kinase/c-Jun to control Schwann cell proliferation and death' Journal of Cell Biology 164, (3) 385-394
Harrisingh MC, Perez-Nadales E, Parkinson DB, Malcolm DS, Mudge AW & Lloyd AC (2004) 'The Ras/Raf/ERK signalling pathway drives Schwann cell dedifferentiation' Embo Journal 23, (15) 3061-3071
Parkinson D, Bhaskaran A, Dickinson S & Kinsella M (2003) 'Regulation of the myelin gene periaxin provides evidence for Krox-20-independent myelin-related signalling in Schwann cells' Mol Cell Neurosci 23, (1) 13-27 ,
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Parkinson DB, Dickinson S, Bhaskaran A, Kinsella MT, Brophy PJ, Sherman DL, Sharghi-Namini S, Alonso MBD, Mirsky R & Jessen KR (2003) 'Regulation of the myelin gene periaxin provides evidence for Krox-20-independent myelin-related signalling in Schwann cells' Molecular and Cellular Neuroscience 23, (1) 13-27
Jessen KR, Mirsky R, Parkinson D, Bhaskaran A & Kazakova N (2003) 'Signals that regulate Schwann cell generation and myelination' Glia 7-7
Parkinson DB, Langner K, Namini SS, Jessen KR & Mirsky R (2002) 'beta-Neuregulin and autocrine mediated survival of Schwann cells requires activity of Ets family transcription factors' Mol Cell Neurosci 20, (1) 154-167 Author Site ,
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Parkinson DB, Dickinson S, Bhaskaran A, Kinsella MT, Brophy PJ, Sherman DL, Namini SS, Alonso MBD, Jessen KR & Mirsky R (2002) 'Krox-20 activates a set of complex changes in Schwann cells that characterize myelination' GLIA S69-S69 Author Site
Bhaskaran A, Parkinson DB, von Hertzen L, Jessen KR & Mirsky R (2002) 'Krox-20 protects Schwann cells from TGF-beta mediated cell death' GLIA S73-S73 Author Site
Mirsky R, Jessen KR, Brennan A, Parkinson D, Dong Z, Meier C, Parmantier E & Lawson D (2002) 'Schwann cells as regulators of nerve development' J Physiol Paris 96, (1-2) 17-24 Author Site ,
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Mirsky R, Jessen KR, Brennan A, Parkinson D, Dong ZP, Meier C, Parmantier E & Lawson D (2002) 'Schwann cells as regulators of nerve development' Journal of Physiology-Paris 96, (1-2) 17-24
Parkinson DB, Dickinson S, Bhaskaran A, Kinsella MT, Brophy PJ, Sherman DL, Namini SS, Alonso MBD, Jessen KR & Mirsky R (2002) 'Krox-20 activates a set of complex changes in Schwann cells that characterize myelination' Glia S69-S69
Bhaskaran A, Parkinson DB, von Hertzen L, Jessen KR & Mirsky R (2002) 'Krox-20 protects Schwann cells from TGF-beta mediated cell death' Glia S73-S73
Bhaskaran A, Parkinson DB, von Hertzen L, Jessen KR & Mirsky R (2001) 'Krox-20 protects Schwann cells from TGF beta mediated cell death' MOLECULAR BIOLOGY OF THE CELL 12, 28A-28A Author Site
Parkinson D, Bunting H, Dong Z & Whitfield J (2001) 'Transforming growth factor beta (TGFbeta) mediates Schwann cell death in vitro and in vivo: examination of c-Jun activation, interactions with survival signals, and the relationship of TGFbeta-mediated death to Schwann cell differentiation' J Neuroscience 21, (21) 8572-8585
Bhaskaran A, Parkinson DB, von Hertzen L, Jessen KR & Mirsky R (2001) 'Krox-20 protects Schwann cells from TGF beta mediated cell death' Molecular Biology of the Cell 12, 28A-28A
Mirsky R, Parkinson DB, Dong Z, Meier C, Calle E, Brennan A, Topilko P, Harris BS, Stewart HJ & Jessen KR (2001) 'Regulation of genes involved in Schwann cell development and differentiation' Prog Brain Res 132, 3-11 Author Site ,
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Parkinson DB, Dong ZP, Bunting H, Whitfield J, Meier C, Marie H, Mirsky R & Jeesen KR (2001) 'Transforming growth factor beta (TGF beta) mediates schwann cell death in vitro and in vivo: Examination of c-jun activation, interactions with survival signals, and the relationship of TGF beta-mediated death to schwann cell differentiation' Journal of Neuroscience 21, (21) 8572-8585
Dong Z, Sinanan A, Parkinson D, Parmantier E, Mirsky R & Jessen KR (1999) 'Schwann cell development in embryonic mouse nerves' J Neurosci Res 56, (4) 334-348 Author Site ,
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Dong Z, Sinanan A, Parkinson D, Parmantier E, Mirsky R & Jessen KR (1999) 'Schwann cell development in embryonic mouse nerves' Journal of Neuroscience Research 56, (4) 334-348 ,
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Perlmutter JS, Tempel LW, Black KJ, Parkinson D & Todd RD (1997) 'MPTP induces dystonia and parkinsonism' Neurology 49, (5) 1432-1438 ,
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Aguilar-Diosdado M, Parkinson D, Corbett JA, Kwon G, Marshall CA, Gingerich RL, Santiago JV & McDaniel ML (1994) 'Potential autoantigens in IDDM. Expression of carboxypeptidase-H and insulin but not glutamate decarboxylase on the beta-cell surface' Diabetes 43, (3) 418-425 Author Site ,
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Parkinson DB, Shaw NJ, Himsworth RL & Thakker RV (1993) 'Parathyroid hormone gene analysis in autosomal hypoparathyroidism using an intragenic tetranucleotide (AAAT) n polymorphism' Human Genetics 91, (3) ,
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Bilous RW, Murty G, Parkinson DB, Thakker RV, Coulthard MG, Burn J, Mathias D & Kendall-Taylor P (1992) 'Autosomal Dominant Familial Hypoparathyroidism, Sensorineural Deafness, and Renal Dysplasia' New England Journal of Medicine 327, (15) 1069-1074 ,
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Fiedorek FT & Parkinson D (1992) 'Carboxypeptidase H processing and secretion in rat clonal beta-cell lines' Endocrinology 131, (3) 1054-1062 ,
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Parkinson D (1992) 'Carboxypeptidase H in bovine pituitary gland: Soluble forms are not processed at the C-terminus' Molecular and Cellular Endocrinology 86, (3) 221-233 ,
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Parkinson DB & Thakker RV (1992) 'A donor splice site mutation in the parathyroid hormone gene is associated with autosomal recessive hypoparathyroidism' Nature Genetics 1, (2) 149-152 ,
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Gredal O, Parkinson D & Nielsen M (1987) 'Binding of [3H]SCH 23390 to dopamine D-1 receptors in rat retina in vitro' European Journal of Pharmacology 137, (2-3) 241-245 ,
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Loewy AD, Marson L, Parkinson D, Perry MA & Sawyer WB (1986) 'Descending noradrenergic pathways involved in the A5 depressor response' Brain Research 386, (1-2) 313-324 ,
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Parkinson D (1985) 'Sensitive analysis of butyrophenone neuroleptics by high-performance liquid chromatography with ultraviolet detection at 254 nm' Journal of Chromatography B: Biomedical Sciences and Applications 341, 465-472 ,
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Parkinson D & Redshaw JD (1984) 'Visible labeling of proteins for polyacrylamide gel electrophoresis with dabsyl chloride' Analytical Biochemistry 141, (1) 121-126 ,
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Parkinson D & Rando RR (1984) 'Ontogenesis of dopaminergic neurons in the post-natal rabbit retina: Pre- and post-synaptic elements' Developmental Brain Research 13, (2) 207-217 ,
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Parkinson D & Callingham BA (1982) 'Irradiation Inactivation Analysis of Acetylcholinesterase and the Effect of Buffer Salts' Radiation Research 90, (2) 252-252 ,
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Parkinson D & Rando RR (1981) 'Evidence for a neurotransmitter role for 5-hydroxytryptamine in chick retina' The Journal of Neuroscience 1, (11) 1211-1217 ,
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Callingham BA & Parkinson D (1977) 'The inhibition of human heart monoamine oxidase [proceedings]' Br J Pharmacol 61, (3) 470P-471P Author Site