Dr Daniel Martin
Professor of Perioperative and Intensive Care Medicine
Peninsula Medical School (Faculty of Health)
I am an intensive care Consultant interested in oxygen physiology, in particular how we respond and adapt to low levels of oxygen. This interest arose from my involvement in a series of research expeditions to high altitude with the Xtreme Everest team. In 2007, as part of my PhD, a group of us took arterial blood samples from one another near the summit of Mount Everest, which had some of the lowest oxygen levels ever reported in humans. In our hunt for key adaptive processes we have measured our mitochondrial function and compared it to that of high altitude Sherpas; we have investigated the function of the microcirculation and conducted a wide range of other studies at various altitudes over the last 15 years. We are now in the process of translating what we have learnt into benefits for patients. This year we will begin a 16,500 patient study across 100 intensive care units in the UK to determine whether giving a little less oxygen than usual to patients on a mechanical ventilator will improve their survival. We have also been looking at the biological mechanisms we identified as important to the Sherpas at altitude in critically ill patients with multiple organ failure. Alongside these studies I am very interested in the benefit of exercise to high-risk patients, particularly those awaiting major surgery. We have used an exercise intervention to train patients waiting for a liver transplant and are about to embark upon a large study to formally evaluate the efficacy of exercise around the time of liver transplant.
Aside from this research portfolio, I am the NIHR Clinical Research Network national deputy lead for anaesthesia, perioperative medicine and pain; the National Institute of Academic Anaesthesia academic training coordinator and Royal College of Anaesthetists Bernard Johnson advisor for academic training. I am passionate about promoting academic training for both doctors in training and allied health professionals. I supervise a number of higher degree students including scientists, medical doctors and allied health professionals.
BSc, MB ChB, FRCA, FFICM, PhD
Other academic activities
I am also the Editor in chief of the Journal of the Intensive Care Society and Director of the Centre for Altitude, Space and Extreme environment medicine.
When not at work, you are most likely to find me scrambling up a Tor on the Moor or heading out to sea with a strong south westerly wind across the starboard bow.