- A226, 22 Portland Square, Drake Circus, Plymouth, PL4 8AA
- +44 1752 584901
- chris.harris@plymouth.ac.uk
Profiles
Professor Christopher Harris
Honorary Professor
School of Psychology (Faculty of Health)
Biography
Biography
Qualifications
Qualifications:
1982-1986 Ph.D. Experimental Psychology City University of New York
1981 1986 M.A., Psychology City University of New York
1973-1974 M.Sc., D.I.C., Applied Optics Imperial College, London
1970-1973 B.Sc. (Hons), A.R.C.S. Physics Imperial College, London
Key publications
(2006) 'The main sequence of saccades optimizes speed-accuracy trade-off' Biological Cybernetics 95, (1) 21-29
Research
Research
Research interests
Clinical
Eye movement disorders - paediatric & adult
Movement disorders- paediatric & adult
Neurometabolic disease
Modelling of pathology
Basic Science
Visual development
Evo-devo
(In)decision-making
Systems modelling
Biological Inspired Robotics
Optimal control
Dimensional reduction
Self-organisation & development
Publications
Publications
Key publications
(2006) 'The main sequence of saccades optimizes speed-accuracy trade-off' Biological Cybernetics 95, (1) 21-29
Key publications are highlighted
Journals
Articles
(2022) 'Analysis of Fibroblast Growth Factor 14 (FGF14) structural variants reveals the genetic basis of the early onset nystagmus locus NYS4 and variable ataxia' European Journal of Human Genetics , DOI Open access
(2020) 'Vestibular rehabilitation in multiple sclerosis: study protocol for a randomised controlled trial and cost-effectiveness analysis comparing customised with booklet based vestibular rehabilitation for vestibulopathy and a 12 month observational cohort study of the symptom reduction and recurrence rate following treatment for benign paroxysmal positional vertigo' BMC Neurology 20, (1) , DOI Open access
(2020) 'Correction: Management of nystagmus in children: a review of the literature and current practice in UK specialist services' Eye 34, (9) 1717-1717 , DOI Open access
(2020) 'Management of nystagmus in children: a review of the literature and current practice in UK specialist services' Eye 34, (9) 1515-1534 , DOI
(2019) 'Arguments for the Adoption of a Nystagmus Care Pathway' British and Irish Orthoptic Journal 15, (1) 82-88 , DOI Open access
(2019) 'The potential and value of objective eye tracking in the ophthalmology clinic' Eye 33, (8) 1200-1202 , DOI Open access
(2019) 'An automated segmentation approach to calibrating infantile nystagmus waveforms' Behavior Research Methods , DOI Open access
(2018) 'Supranuclear eye movements and nystagmus in children: A review of the literature and guide to clinical examination, interpretation of findings and age-appropriate norms' Eye , DOI Open access
(2017) 'The effect of gaze angle on visual acuity in infantile nystagmus' Investigative Ophthamoloy and Visual Science Open access
(2015) 'Investigating decision rules with a new experimental design: the EXACT paradigm' Frontiers in Behavioral Neuroscience 9, , DOI Open access
(2015) 'Human optokinetic nystagmus and spatial frequency' Journal of Vision 15, (13) 7-7 , DOI Open access
(2015) 'A Computational Model of Innate Directional Selectivity Refined by Visual Experience' Scientific Reports 5, (0) 0-0 , DOI Open access
(2014) 'Grating Visual Acuity in Infantile Nystagmus in the Absence of Image Motion' INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 55, (4) 2682-2686 , DOI Open access
(2014) 'A proto-architecture for innate directionally selective visual maps' PLoS One 9, (7) , DOI Open access
(2014) 'Do muscle synergies reduce the dimensionality of behavior?' Front Comput Neurosci 8, , DOI Open access
(2013) 'Stress and Visual Function in Infantile Nystagmus Syndrome' INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 54, (13) 7943-7951 , DOI Open access
(2013) 'The distribution of quick phase interval durations in human optokinetic nystagmus' Exp Brain Res 224, (2) 179-187 , DOI Open access
(2012) 'On the convergence of time interval moments: caveat sciscitator' J Neurosci Methods 205, (2) 345-356 , DOI
(2012) 'Infantile Nystagmus Syndrome: What Can fMRI Tell Us?' JOURNAL OF PEDIATRIC OPHTHALMOLOGY & STRABISMUS 49, (3) 189-189
(2009) 'Biomimetics of human movement: functional or aesthetic?' Bioinspiration & Biomimetics 4,
(2008) 'A randomized controlled trial of miglustat in Gaucher disease type 3' Annals of Neurology 64, (5) 514-522 , DOI
(2007) 'Allelic variation of the FRMD7 gene in congenital idiopathic nystagmus' ARCHIVES OF OPHTHALMOLOGY 125, (9) 1255-1263 , DOI
(2007) 'A study of EEG, electroretinogram, visual evoked potential, and eye movements in classical lissencephaly' Developmental Medicine & Child Neurology 42, (1) 48-52 , DOI
(2007) 'Infantile nystagmus adapts to visual demand' Perception 36, (2) 315-315
(2007) 'Infantile nystagmus adapts to visual demand' Investigative Ophthalmology & Visual Science 48, (5) 2089-2094
(2007) 'The importance of correct phenotyping in Gaucher disease' Journal of Child Neurology 22, (8) 1056-1057
(2006) 'A distal model of congenital nystagmus as nonlinear adaptive oscillations' Nonlinear Dynamics 44, (1-4) 367-380
(2006) 'Fine mapping of the X-linked recessive congenital idiopathic nystagmus locus at Xq24-q26.3' Molecular Vision 12, (136-38) 1211-1216
(2006) 'Infant saccades are not slow' Developmental Medicine and Child Neurology 48, (8) 662-667
(2006) 'The main sequence of saccades optimizes speed-accuracy trade-off' Biological Cybernetics 95, (1) 21-29
(2005) 'EYE MOVEMENTS AS 'NEUROMARKERS' IN NEUROMETABOLIC DISEASES' JOURNAL OF INHERITED METABOLIC DISEASE 28, 149-149
(2005) 'Saccades are not special: they are the same as finger movements' SPATIAL VISION 18, (4) 499-500
(2005) 'SACCADIC EYE MOVEMENTS IN D409H-N370S GAUCHER HETEROZYGOTES' JOURNAL OF INHERITED METABOLIC DISEASE 28, 150-150
(2004) 'Paediatric non-neuronopathic Gaucher disease: recommendations for treatment and monitoring' EUROPEAN JOURNAL OF PEDIATRICS 163, (2) 67-75 , DOI
(2004) 'Pediatric non-neuronopathic Gaucher disease: presentation, diagnosis and assessment. Consensus statements' EUROPEAN JOURNAL OF PEDIATRICS 163, (2) 58-66 , DOI
(2004) 'Bone conduction auditory brainstem responses in infants' Journal of Laryngology and Otology 118, (2) 117-122
(2004) 'Deterioration of the auditory brainstem response in children with type 3 Gaucher disease' Neurology 63, (2) 385-387
(2004) 'Exploring smoothness and discontinuities in human motor behaviour with Fourier analysis' Mathematical Biosciences 188, 99-116
(2004) 'Optimal impedance control for task achievement in the presence of signal-dependent noise' Journal of Neurophysiology 92, (2) 1199-1215
(2003) 'A model of neuronopathic Gaucher disease' Journal of Inherited Metabolic Disease 26, (7) 629-639
(2003) 'Familial vestibulocerebellar disorder maps to chromosome 13q31-q33: a new nystagmus locus' Journal of Medical Genetics 40, (1) 37-41
(2003) 'Morbus Gaucher. Auditory brainstern response and eye movement in diagnosis of Morbus Gaucher type 3' Monatsschrift Kinderheilkunde 151, (8) 854-862
(2003) 'Ocular tilt reaction due to a mesencephalic lesion in juvenile polyarteritis nodosa' American Journal of Ophthalmology 135, (2) 249-251
(2003) 'Vertical optokinetic nystagmus and saccades in normal human subjects' Investigative Ophthalmology & Visual Science 44, (9) 3833-3841
(2002) 'Temporal uncertainty in reading the neural code (proportional noise)' Biosystems 67, (1-3) 85-94
(2002) 'Verbal overshadowing in voice recognition' Applied Cognitive Psychology 16, (8) 973-980
(2002) 'Adaptive control of saccades in children with dancing eye syndrome' Neurobiology of Eye Movements: from Molecules to Behavior 956, 449-452
(2001) 'Familial vestibulocerebellar disorder maps to chromosome 13q31-q33: a new nystagmus locus' AMERICAN JOURNAL OF HUMAN GENETICS 69, (4) 654-654
(2001) 'Diagnosing children presenting with asymmetric pendular nystagmus' Dev Med Child Neurol 43, (9) 622-627 , DOI
(2001) 'Audiometric abnormalities in children with Gaucher disease type 3' Neuropediatrics 32, (3) 136-141 , DOI
(2001) 'Comparison of the main sequence of reflexive saccades and the quick phases of optokinetic nystagmus' British Journal of Ophthalmology 85, (12) 1477-1483
(2001) 'Outcome of children presenting with asymmetric pendular nystagmus' Developmental Medicine and Child Neurology 43, 622-627
(2001) 'Spontaneous reversal of nystagmus in the dark' British Journal of Ophthalmology 85, (4) 428-431
(2000) 'Chiasmal maldevelopment('achiasmia') indicated by VEP and eye movement studies though not by MRI scanning: A case study' INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 41, (4) S702-S702
(2000) 'Spectral characteristics of optokinetic quick phases' INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 41, (4) S700-S700
(2000) 'The temporal main sequence optokinetic nystagmus' INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 41, (4) S701-S701
(2000) 'A study of EEG, electroretinogram, visual evoked potential, and eye movements in classical lissencephaly' Dev Med Child Neurol 42, (1) 48-52 , DOI
(2000) 'Abnormal supranuclear eye movements in the child - a practical guide to examination and interpretation' Survey of Ophthalmology 44, 479-506
(2000) 'Abnormal vertical optokinetic nystagmus in infants and children' British Journal of Ophalmology 84, 451-455
(2000) 'Reverse and converse ocular bobbing with synkinetic blinking and opsoclonus in a child with Epstein-Barr virus encephalitis after bone marrow transplant for MPS I' British Journal of Ophthalmology 84, 1207-1208
(2000) 'Vertical or asymmetric nystagmus need not imply neurologic disease' British Journal of Ophthalmology 84, 175-180
(1999) 'Saccadic strategies in children with hemianopia - Reply' DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY 41, (6) 429-430 , DOI
(1999) 'Fourier analysis of saccades in chronic sixth nerve palsy with botulinum toxin' INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 40, (4) S61-S61
(1999) 'A study of EEG, ERG, VEP and eye movements in isolated lissencephaly' Developmental Medicine & Child Neurology 42, 48-52
(1999) 'Ocular motor abnormalities in Gaucher disease' Neuropediatrics 30, 289-293
(1999) 'Visual-evoked potential evidence of chiasmal hypoplasia' Ophthalmology 106, 2354-2361
(1998) 'Familial congenital saccade initiation failure and isolated cerebellar vermis hypoplasia' Developmental Medicine and Child Neurology 40, 775-779
(1998) 'On the optimal control of behaviour: a stochastic perspective' Journal of Neuroscience Methods 83, 73-88
(1998) 'The Fourier analysis of biological transients' Journal of Neuroscience Methods 83, 15-34
(1997) 'Eye movement abnormalities in a case of Tourette syndrome' Dev Med Child Neurol 39, (4) 270-273
(1997) 'Saccadic eye movement strategies in children with homonymous hemianopia' INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 38, (4) 3050-3050
(1997) 'Spectral analysis of cross modulation products in 'beat' VEPs to dichoptic two frequency stimulation' INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 38, (4) 4613-4613
(1997) 'Accelerating slow phases in epileptic nystagmus: implications for congenital nystagmus' PERCEPTION 26, (6) 780-780
(1997) 'Epileptic nystagmus: evidence of cortical oculomotor function from early infancy' PERCEPTION 26, (6) 763-764
(1997) 'Eye movement recording in non-infantile Gaucher disease: a preliminary report' Gaucher Clinical Perspectives 5, 7-10
(1997) 'Monocular optokinetic symmetry in early onset esotropia' PERCEPTION 26, (6) 789-789
(1997) 'Paradoxical monocular OKN asymmetry in an achiasmic acallosal child' PERCEPTION 26, (6) 782-782
(1997) 'Saccadic strategies in hemianopic children' PERCEPTION 26, (6) 780-780
(1997) 'Spectral power and time-frequency distributions of beat VEPs' PERCEPTION 26, (6) 775-776
(1996) 'A new remote sensing technique for measuring head position using a scanning laser system' INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 37, (3) 1261-1261
(1996) 'Eye movements in children with Down's Syndrome' INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 37, (3) 1279-1279
(1996) 'Monocular optokinetic symmetry' INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 37, (3) 1036-1036
(1996) 'Intermittent horizontal saccade failure ('ocular motor apraxia') in children' Br J Ophthalmol 80, (2) 151-158 , DOI
(1996) 'Achiasmia in a case of midline craniofacial cleft with seesaw nystagmus' British Journal of Ophthalmology 80, 1023-1027
(1996) 'Neural network simulations of the primate oculomotor system .2. Frames of reference - Commentary' BRAIN RESEARCH BULLETIN 40, (5-6) 344-344 , DOI
(1996) 'Delayed visual maturation in infants: a disorder of figure-ground separation?' Brain Res Bull 40, (5-6) 365-369 , DOI
(1996) 'The role of ERG/VEP and eye movement recordings in children with ocular motor apraxia' Eye (Lond) 10 ( Pt 1), 53-60 , DOI
(1995) 'Neuroradiological and eye movement correlates in children with intermittent saccade failure: "ocular motor apraxia"' Neuropediatrics 26, (6) 298-305 , DOI
(1995) 'The optokinetic response differences between congenital profound and nonprofound unilateral visual deprivation' Ophthalmology 102, (11) 1615-1622 , DOI
(1995) 'ISOLATED DELAYED VISUAL MATURATION - AN OCULOMOTOR IMMATURITY' INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 36, (4) S352-S352
(1995) 'Does saccadic undershoot minimize saccadic flight-time? A Monte-Carlo study' Vision Res 35, (5) 691-701 , DOI
(1995) 'Electrophysiological and eye-movement abnormalities in children with the Bardet-Biedl syndrome' J Pediatr Ophthalmol Strabismus 32, (6) 364-367 , DOI
(1994) 'OCULOMOTOR AND NEURORADIOLOGICAL CORRELATES IN CONGENITAL SACCADE PALSY (OCULAR MOTOR APRAXIA)' INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 35, (4) 2034-2034
(1994) 'SACCADES IN 2 CONTRASTING HEMIDECORTICATE CASES - IMPLICATIONS FOR BLINDSIGHT' INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 35, (4) 1545-1545
(1994) 'Vertical saccade palsy: a presenting sign of Niemann-Pick type IIS' European Journal of Neurology 1, 93-95
(1993) 'Are express saccades anticipatory?' Behavior & Brain Sciences 16, 593-594
(1993) 'Eye movement and electrophysiological findings in an infant with hemispheric pathology' Developmental Medicine & Child Neurology 35, 431-448
(1993) 'Eye movements in a familial vestibulocerebellar disorder' Neuropediatrics 24, 117-122
(1993) 'Eye movements in children with opsoclonus-polymyoclonus' Neuropediatrics 24, 218-223
(1993) 'Human ocular motor neural integrator failure' Neuro-ophthalmology 24, 25-34
(1993) 'Oculomotor signs in infantile Gaucher disease' Neuro-Ophthalmology 13, 151-155
(1993) 'The development of saccadic accuracy in the first 7 months' Clinical Visual Sciences 8, 85-96
(1992) 'Aspects of albinism' Ophthalmic Paediatrics and Genetics 13, 89-100
(1992) 'Eye movement tics' British Journal of Ophthalmology 76, 697-699
(1992) 'Nystagmus in infancy' British Journal of Ophthalmology 76, 434-437
(1992) 'The objective assessment of abnormal eye movements in infants and young children' Australian and New Zealand Journal of Ophthalmology 20, 185-195
(1992) 'The use of video in assessing and illustrating abnormal eye movements in young children' Journal of Audiovisual Media in Medicine 15, 113-116
(1990) 'Variability of refixations in infants' Infant Behavior and Development 13, (3) 321-342 , DOI
(1990) 'Fourier analysis of saccades in monkeys and humans' Journal of Neurophysiology 63, (4) 877-886 , DOI
(1990) 'Fourier analysis of primate saccades' Journal of Neurophysiology 63, 877-886
(1990) 'Refixation stability in infants' Infant Behavior and Development 13, 321-342
(1989) 'The ethology of saccades: a non cognitive model' Biological Cybernetics 60, 401-410
(1988) 'The distribution of fixations in infants and naive adults' Vision Research 28, 419-432
(1988) 'The distribution of fixation durations in infants and naive adults' Vision Res 28, (3) 419-432 , DOI
(1984) 'Artificial eye for assessing corneal reflection eye trackers' Behavioral Research Methods and Instrumentation, 16, 437-438
(1984) 'Characteristics of saccades in human infants' Vision Research 24, 1771-1780
(1984) 'Instrument considerations in measuring fast eye movements' Behavioral Research Methods and Instrumentation 16, 341-350
(1983) 'Linearizing the z axis of an oscilloscope display' Behavioral Research Methods and Instrumentation 15, 622-622
(1981) 'A method for calibrating an eye monitoring system for use with infants' Behavioral Research Methods and Instrumentation 13, 11-17
Reviews
(2013) 'Latent Nystagmus' Optometry Today 54, 49-53
(2013) 'Optokinetic nystagmus' Optometry Today 53, 71-76
Letters
(2014) 'Author response: Grating visual acuity in infantile nystagmus in the absence of image motion' Invest Ophthalmol Vis Sci 55, (8) 4955-4957 , DOI Open access
(1997) 'Opsoclonus: brainstem or cerebellum?' Neuroophthalmology 18, 95-96
(1993) 'Autosomal recessive cerebellar hypoplasia' Pediatric Neurology 9, 247-247
(1992) 'Ocular motility anomalies in developmental misdirection of the optic chiasm' American Journal of Ophthalmology 113, 601-602
Books
Harris CM; Gottlob I; Sanders J (2012) The Challenge of Nystagmus. Nystagmus Network Press
Chapters
(2012) 'Infantile nystagmus: an adaptationist approach' in Harris C; Gottlob I; Sanders J The Challenge of Nystagmus 27-48
(2012) 'The impact of stress on visual performance in congenital nystagmus' in Gottlob I; Harris C; Sanders J The Challenge of Nystagmus 239-260
(2011) 'Oculomotor developmental pathology: an evo-devo perpsective' in Liversedge S; Gilchrist I; Everling S Oxford Handbook of Eye Movements Oxford University Press 663-686
(2002) 'Time-optimality and the spectral overlap of saccadic eye movements' Neurobiology of Eye Movements: From Molecules to Behavior Neurobiology of Eye Movements: From Molecules to Behavior 414-417
(2000) 'Eye Movement Disorders' in Moore A Fundamentals of Clinical Ophthalmology: Paediatrics
(1997) 'Nystagmus and eye movement disorders' Paediatric Ophthalmology 2nd ed 869-896
(1997) 'Other eye movement disorders' in Taylor D Paediatric Ophthalmology 2nd ed 897-924
(1995) 'An ERG, VEP and eye movement assessment of children with Bardet-Biedl syndrome' in Lennerstrand G Update on Strabismus and Pediatric Ophthalmology 549-552
(1995) 'Problems in modelling congenital nystagmus: towards a new model' in Findlay JM; Walker RW; Kentridge RW Eye Movement Research: Mechanisms, Processes and Applications Elsevier 239-253
(1995) 'The development of eye movements in infancy' in Lennerstrand G Update on Strabismus and Pediatric Ophthalmology 140-143
(1993) 'On the reversibility of Markov scanning in free viewing' in Brogan D; Gale A; Carr K Vision Search 2 Taylor & Francis 123-135
(1990) 'Does foveal immaturity influence the infant's consistency of point of regard' in Groner R; d'Ydewalle G; Parham R From eye to mind: Information acquisition in perception, search and reading Elsevier Science 80-90
Conference Papers
(2014) 'Development of joint stiffness and learnability' 2014 Joint IEEE International Conferences on Development and Learning and Epigenetic Robotics (ICDL-Epirob) 0-/-1/20140-/-1/2014IEEE , DOI Open access
(2013) 'Developing learnability — The case for reduced dimensionality' 2013 IEEE International Conference on Development and Learning and Epigenetic Robotics (ICDL) 8-/-0/20138-/-0/2013IEEE , DOI
(2013) 'Visual acuity in infantile nystagmus in the absence of image motion'
(2012) 'Biomimetics of choice behaviour for autonomous agents' FIRA-TAROS 2012 Bristol 96-104
(2012) 'Effect of physical variation on the reduced dimensional control of a mass-spring-damper chain system' Development and Learning and Epigenetic Robotics (ICDL), 2012 IEEE International Conference 1-2
(2010) 'The Effects of Stress on INS'
(2009) 'DOES FISHER INFORMATION CONSTRAIN HUMAN MOTOR CONTROL?' 414-420
(2008) 'Biomimetics and proportional noise in motor control' 37-43
(2008) 'Using optimality to predict photoreceptor distribution in the retina' 408-415
(2005) 'Boundary conditions in human movement I: Constraining constraints' 629-633
(2005) 'Boundary conditions in human movement II: The fourier approach' 634-637
(2005) 'Boundary conditions in human movement III: Fourier analysis of reaching' 638-640
(2004) 'Relation among duration, position variance, and muscle activity in human arm movement control' 2859-2863
(2004) 'Relation among duration, position variance, and muscle activity in human arm movement control' 1725-1729
Patents
(2007) METHOD AND APPARATUS FOR CONFIGURING A COMMUNICATION CHANNEL. EP1929674
Presentations and posters
'Vestibular Rehabilitation in People with Multiple Sclerosis'
Personal
Personal
Other academic activities
Clinical assessment of eye movement disorders.
Consultant Clinical Scientist
Royal Eye Infirmary
Plymouth Hospitals NHS Trust