Dr Ann Rigby-Jones
Profiles

Dr Ann Rigby-Jones

Lecturer in Pharmacology (Education)

Peninsula Medical School (Faculty of Health)

Dr Ann Rigby-Jones can be contacted through arrangement with our Press Office, to speak to the media on these areas of expertise.
  • Pharmacology
  • Pharmacometrics
Biography

Biography

Lecturer in Pharmacology (Education)
  • Programme Lead MSc Physician Associate Studies
  • Programme Lead MSc Physician Associate Studies (Apprenticeship)
  • Programme Lead MSc Physician Associate Studies (Top-Up)
  • Academic Lead for the Intercalated Degree (BMBS)
  • Pharmacology curriculum lead: MSc Physician Associate Studies
  • Pharmacology curriculum co-lead: Bachelor of Medicine, Bachelor of Surgery (BMBS)

Qualifications

  • Postgraduate Certification in Academic Practice (PgCAP) 2013 University of Plymouth 
  • PhD in Medical Studies for a thesis entitled: The Pharmacokinetics and Pharmacodynamics of Propofol in the Critically Ill Child , Peninsula Medical School, Universities of Exeter & Plymouth, 2005
  • BSc (Combined Honours) Cell Biology & Immunology with Chemistry. University of Plymouth, 1997 

Professional membership

  • Member of the Royal Society of Chemistry (MRSC) 
  • Senior Fellow of Advance HE (SFHEA) 
 

Roles on external bodies

  • External Examiner: MSc Physician Associate University of Worcester
  • Member of the Editorial Board: Journal of Clinical Monitoring and Computing 
  • The Peninsula Medical School representative at the Physician Associate Schools Council
  • Member of the Education (Prescribing & Assessment); Research and Professional Development  Workstreams: Physician Associate Schools Council
  • Primary School Governor: Hooe Primary Academy
Teaching

Teaching

Teaching interests

My current teaching and leadership roles within the Medical School include: 
School Roles:
  • Member of the Senior Management Team
  • Deputy Chair of the Medical School Teaching, Learning and Quality Committee
  • Member of the Quality Excellence Unit

MSc Physician Associate Studies
  • Programme Lead: Standard entry (2 year, fulltime, on campus programme), Apprenticeship, Top-Up (PgDip to MSc conversion programme)
  • Curriculum Lead for Pharmacology & Therapeutics 
  • Module Lead for Personal and Professional Development in Years 1 and 2
  • Module Lead Evidence in Practice (Year 2)
  • Module Co-Lead Evidence Based Practice (Year 1)
  • Academic Tutor
BMBS
  • Academic Lead for Intercalation (BMBS)
  • Deputy Chair of the Medical School Teaching, Learning and Quality Committee
  • Curriculum Co-Lead for Pharmacology & Therapeutics 
  • Life Science Resource Centre facilitator for Year 2 BMBS students and BMBS Foundation student
 

Staff serving as external examiners

  • External Examiner: MSc Physician Associate University of Worcester
Research

Research

Research interests

Member of the Faculty of Health Ethics Committee
Current Research Interests

Medical Education
  • Defining, teaching and assessing of medical professionalism
  • Interprofessional Learning 
  • Preparedness of practice (Physician Associates)
  • Preparedness for prescribing 

Pharmacology
Population pharmacokinetics & pharmacodynamics, novel drug compounds, anaesthetic drug use in patients at the extremes of weight (paediatric critical care, bariatric surgery patients), health hazards related to use of medical plastics and dental composites (toxicokinetics)

Research degrees awarded to supervised students

Steven Wileman: PhD 2018
Endocrine Disrupting Compounds in Composite Materials for Paediatric Dentistry
Publications

Publications

Key publications

Key publications are highlighted

Journals
Articles
Sneyd J, Gambus P & Rigby-Jones A (2021) 'The current status of perioperative hypnotics, the role of benzodiazepines and the case for remimazolam' British Journal of Anaesthesia , DOI Open access
Burr S, Martin T, Edwards J, Ferguson C, Gilbert K, Gray C, Hill A, Hosking J, Johnstone K & Kisielewska J (2021) 'Standard setting anchor statements: a double cross-over trial of two different methods' MedEdPublish 10, (1:32) 1-13 Publisher Site , DOI Open access
Absalom AR, Rigby-Jones A, Rushton AR & Sneyd J (2020) 'De-mystifying the ‘Mixifusor’' Paediatric Anaesthesia 30, (12) 1292-1298 , DOI Open access
Sneyd J & Rigby-Jones A (2020) 'Remimazolam; a role for anaesthesia/ sedation?' Current Opinion in Anaesthesiology , DOI Open access
Wileman SJ, Hanks S, Priston M, Deperalta T, Rigby-Jones A & Sneyd J (2016) 'Endocrine disruptors in paediatric patients & in-vitro sealant weight variability' Dental Materials 32, Author Site , DOI
Brown S, Daugherty M, Park L, Brittain J, Priston M, Rigby-Jones A, McGrath JS & Sneyd JR (2014) 'Systemic concentrations of levobupivacaine administered by rectus sheath catheter' BRITISH JOURNAL OF ANAESTHESIA 112, (1) 188P-188P
Rose RJ, Priston MJ, Rigby-Jones AE & Sneyd JR (2012) 'The effect of temperature on di(2-ethylhexyl) phthalate leaching from PVC infusion sets exposed to lipid emulsions' Anaesthesia 67, (5) 514-520 Author Site , DOI
Sneyd JR, Rigby-Jones AE, Cross M, Tominaga H, Shimizu S, Ohkura T & Grimsehl K (2012) 'First human administration of MR04A3: a novel water-soluble nonbenzodiazepine sedative' Anesthesiology 116, (2) 385-395 Author Site , DOI Open access
Rigby-Jones AE & Sneyd JR (2012) 'Pharmacokinetics and pharmacodynamics--is there anything new?' Anaesthesia 67, (1) 5-11 Author Site , DOI
Rigby-Jones AE & Sneyd JR (2011) 'Propofol and children--what we know and what we do not know' Paediatr Anaesth 21, (3) 247-254 Author Site , DOI Open access
Sneyd JR & Rigby-Jones AE (2010) 'New drugs and technologies, intravenous anaesthesia is on the move (again)' Br J Anaesth 105, (3) 246-254 Author Site , DOI Open access
Rigby-Jones AE, Sneyd JR, Vijn P, Boen P & Cross M (2010) 'First administration to man of Org 25435, an intravenous anaesthetic: A Phase 1 Clinical Trial' BMC Anesthesiol 10, Author Site , DOI Open access
Rose RJ, Priston MJ, Rigby-Jones AE & Sneyd JR (2009) 'Effect of temperature on plasticizer release [di(2-ethylhexyl)phthalate] from TIVA infusion sets' BRITISH JOURNAL OF ANAESTHESIA 102, (4) 581-582
Ravenelle F, Vachon P, Rigby-Jones AE, Sneyd JR, Le Garrec D, Gori S, Lessard D & Smith DC (2008) 'Anaesthetic effects of propofol polymeric micelle: a novel water soluble propofol formulation' Br J Anaesth 101, (2) 186-193 Author Site , DOI
Rigby-Jones AE, Sneyd JR, Ravenelle F, Vachon P, Le Garrec D, Gori S, Lessard D & Smith DC (2008) 'Pharmacokinetics and anaesthetic effects of propofol-PM: a novel water soluble propofol formulation' ANAESTHESIA 63, (12) 1392-1393 , DOI
Sneyd JR & Rigby-Jones AE (2007) 'Effect site: who needs it?' Br J Anaesth 98, (6) 701-704 Author Site , DOI
Rigby-Jones AE, Priston MJ, Sneyd JR, McCabe AP, Davis GI, Tooley MA, Thorne GC & Wolf AR (2007) 'Remifentanil-midazolam sedation for paediatric patients receiving mechanical ventilation after cardiac surgery' Br J Anaesth 99, (2) 252-261 Author Site , DOI
Sneyd JR & Rigby-Jones AE (2007) 'Effect site: who needs it?' British Journal of Anaesthesia 98, (6) 701-704
Murray DM, Thorne GC, Rigby-Jones AE, Tonucci D, Grimes S, Tooley MA & Wolf AR (2004) 'Electroencephalograph variables, drug concentrations and sedation scores in children emerging from propofol infusion anaesthesia' Paediatric Anaesthesia 14, (2) 143-151 , DOI
Sewell GJ, Rigby-Jones AE & Priston MJ (2003) 'Stability of intravesical epirubicin infusion: a sequential temperature study' J Clin Pharm Ther 28, (5) 349-353 Author Site , DOI Open access
Rigby-Jones AE, Nolan JA, Priston MJ, Wright PMC, Sneyd JR & Wolf AR (2002) 'Pharmacokinetics of propofol infusions in critically ill neonates, infants, and children in an intensive care unit' Anesthesiology 97, (6) 1393-1400 Author Site , DOI
Rigby-Jones AE, Nolan JA, Priston MJ, Wright PMC, Sneyd JR & Wolf AR (2002) 'Pharmacokinetics of propofol infusions in critically ill neonates, infants, and children in an intensive care unit' Anesthesiology 97, (6) 1393-1400
Letters
Rigby-Jones A & Sneyd JR (2008) 'Cardiovascular changes after achieving constant effect site concentration of propofol' Anaesthesia 63, (7) Author Site , DOI
Chapters
Rigby-Jones AE & Burr SA (2024) 'Curare (d-Tubocurarine)' Encyclopedia of Toxicology Elsevier 353-357 , DOI
Presentations and posters
Priston MJ, Hughes J, Rigby-Jones AE & Sneyd JR Priston MJ, Hughes J, Rigby-Jones AE & Sneyd JR 'Plasticizer release (DEHP) from TIVA infusion sets'
Rigby-Jones AE, Priston MJ, Thorne GC, Tooley MA, Sneyd JR & Wolf AR Rigby-Jones AE, Priston MJ, Thorne GC, Tooley MA, Sneyd JR & Wolf AR 'Population pharmacokinetics of remifentanil in critically ill post cardiac neonates, infants and children'
Murray DM, Rigby-Jones AE, Tonucci D, Grimes SB, Thorne GC, Tooley MA & Wolf AR Murray DM, Rigby-Jones AE, Tonucci D, Grimes SB, Thorne GC, Tooley MA & Wolf AR 'Propofol blood levels, clinical sedation scores and electrophysiological variables in children emerging from propofol infusion anaesthesia'
Personal

Personal

Reports & invited lectures

Pharmacology 
2022 Euroanaesthesia, Milan 
Euroanaesthesia is recognised worldwide as one of the most important and influential annual congresses in anaesthesiology and intensive care.  
Invited speaker on the topic of 'New propofol analogues'
2022 European Society of Anaesthesiology and Intensive Care (ESAIC) 
ESAIC holds the most prominent position in the community of anaesthesiologists in Europe and elsewhere.  
Invited speaker: My presentation discussed the limitations of currently available intravenous sedatives and how these might be addressed, in part, with new to market pharmaceuticals
Medical Education Scholarship
My interests and pedagogical research in the area of medical professionalism and reflective practice were recognised with two invitations to run workshops at the national Physician Associate Educators conference. This is the annual conference for the Physician Associate Schools Council, attended by Physician Associate educators from across the UK and Ireland.  
 
  • Physician Associate Educators Conference, Keele, 2021 
Workshop: Supporting the Development of Professionalism in Physician Associate Students​ 
 
  • Physician Associate Educators Conference, Wolverhampton 2018 
Workshop: Medical Professionalism: Assessing the Intangible  

Conferences organised

2022 Personalised Assessment Conference, University of Plymouth

Other academic activities

  • I am a member of the editorial board for the Journal of Clinical Monitoring and Computing (pharmacology and drug modelling section). 
  • I regularly provide reviews for the British Journal of Anaesthesia.