Peninsula Clinical Trials Unit: publications
Results and protocol publications
Latest publication
The ENRICH Study – The Lancet – October 2025
2025
The STEPS II Study – BMJ Open – September 2025
Efficacy of peroneal nerve functional electrical stimulation (FES) for the reduction of bradykinesia in Parkinson’s disease: an assessor-blinded randomised controlled trial – study protocol
Efficacy of peroneal nerve functional electrical stimulation (FES) for the reduction of bradykinesia in Parkinson’s disease: an assessor-blinded randomised controlled trial – study protocol
The SPECTROM PDP Study - NIHR Open Research - September 2025
Short-term Psycho-Education for Carers To Reduce Over Medication of people with intellectual disabilities: Programme Development Project
Short-term Psycho-Education for Carers To Reduce Over Medication of people with intellectual disabilities: Programme Development Project
Variation in paediatric splenic trauma management in adult and combined major trauma centres in England - Clinical Radiology - June 2025
Treatment options for paediatric splenic injuries include conservative management, splenic embolisation, and splenectomy
Treatment options for paediatric splenic injuries include conservative management, splenic embolisation, and splenectomy
The APHID Study – Frontiers in Health Services – May 2025
A novel way to understand and communicate the burden of AntiPsycHotic prescribing for adults across specialist Intellectual Disability services in England and Wales: the APHID feasibility study protocol
A novel way to understand and communicate the burden of AntiPsycHotic prescribing for adults across specialist Intellectual Disability services in England and Wales: the APHID feasibility study protocol
The Spectrom PDP Study – Journal of Mental Health Research in Intellectual Disabilities – May 2025
A Feasibility Cluster RCT Involving SPECTROM Staff Training Program to Help Reduce the Overmedication of Adults with Intellectual Disabilities
A Feasibility Cluster RCT Involving SPECTROM Staff Training Program to Help Reduce the Overmedication of Adults with Intellectual Disabilities
The OBtAIN-PD Study – BMJ Open – May 2025
Evaluating the occupation-based complex intervention for living well with anxiety and Parkinson's disease (OBtAIN-PD) in community rehabilitation teams in the UK: a feasibility cluster randomised controlled trial protocol
Evaluating the occupation-based complex intervention for living well with anxiety and Parkinson's disease (OBtAIN-PD) in community rehabilitation teams in the UK: a feasibility cluster randomised controlled trial protocol
Pattern of psychotropic prescribing in adults with intellectual disabilities in the community settings in the UK: A cross-sectional view - Research in Developmental Disabilities - May 2025
To provide a cross-sectional view of the pattern of psychotropic medicine prescriptions with the reasons for their use among adults with intellectual disabilities in community settings in the UK
To provide a cross-sectional view of the pattern of psychotropic medicine prescriptions with the reasons for their use among adults with intellectual disabilities in community settings in the UK
Management of penetrating splenic trauma; is it different to the management of blunt trauma? - International Journal of the Care of the Injured - May 2025
We compare the treatment and outcomes of penetrating and blunt splenic trauma at Major Trauma Centres (MTC) within the UK
We compare the treatment and outcomes of penetrating and blunt splenic trauma at Major Trauma Centres (MTC) within the UK
The ESKD Study - BMC Nephrology - April 2025
Navigating the complexities of end-stage kidney disease from risk factors to outcome: insights from the UK Biobank cohort
Navigating the complexities of end-stage kidney disease from risk factors to outcome: insights from the UK Biobank cohort
The EMaPP Study – Pilot and Feasibility Studies – April 2025
Evaluating the Management of chronic Pelvic girdle Pain following pregnancy (EMaPP): a randomised controlled feasibility trial
Evaluating the Management of chronic Pelvic girdle Pain following pregnancy (EMaPP): a randomised controlled feasibility trial
The BREEZE-IPF Study - BMJ Open - March 2025
Complex breathlessness intervention in idiopathic pulmonary fibrosis: a feasibility, wait-list design randomised controlled trial
Complex breathlessness intervention in idiopathic pulmonary fibrosis: a feasibility, wait-list design randomised controlled trial
Alimentary Pharmacology and Therapeutics – March 2025
Balancing Cost and Consequence of Colon Capsule Endoscopy in Colorectal Cancer Pathways—Finding the Sweet Spot. Authors' Reply
Balancing Cost and Consequence of Colon Capsule Endoscopy in Colorectal Cancer Pathways—Finding the Sweet Spot. Authors' Reply
The Spectrom PDP Study – Research in Developmental Disabilities – March 2025
Pattern of psychotropic prescribing in adults with intellectual disabilities in the community settings in the UK: A cross-sectional view
Pattern of psychotropic prescribing in adults with intellectual disabilities in the community settings in the UK: A cross-sectional view
The Spectrom PDP Study – Journal of Mental Health Research in Intellectual Disabilities – March 2025
Short-Term PsychoEducation for Carers to Help Reduce the Over Medication of People with Intellectual Disabilities Programme Development Project: A Feasibility Randomized Controlled Trial Protocol
Short-Term PsychoEducation for Carers to Help Reduce the Over Medication of People with Intellectual Disabilities Programme Development Project: A Feasibility Randomized Controlled Trial Protocol
Alimentary Pharmacology and Therapeutics – February 2025
Multicentre Study of 10,369 Symptomatic Patients Comparing the Diagnostic Accuracy of Colon Capsule Endoscopy, Colonoscopy and CT Colonography
Multicentre Study of 10,369 Symptomatic Patients Comparing the Diagnostic Accuracy of Colon Capsule Endoscopy, Colonoscopy and CT Colonography
The SPEED Study - PLOS One - January 2025
Decision to treat acute traumatic splenic artery injury in the context of trauma protocol
Decision to treat acute traumatic splenic artery injury in the context of trauma protocol
Digital health technologies and self-efficacy in Parkinson’s - BMJ Open - January 2025
Prior research has identified that people with Parkinson’s reporting lower levels of self-efficacy exhibit worsening motor and non-motor symptomology, reduced quality of life, and self-management
Prior research has identified that people with Parkinson’s reporting lower levels of self-efficacy exhibit worsening motor and non-motor symptomology, reduced quality of life, and self-management
Improving recruitment and retention of people with Parkinson's disease to clinical studies - Sage Journals - January 2025
To identify successful recruitment and retention methodologies for clinical research studies in PD
To identify successful recruitment and retention methodologies for clinical research studies in PD
2024
Retrospective Observational Study of the Management of Blunt Traumatic Splenic Injury 2017–2022 at Major Trauma Centres in England. What is the Current Role of Splenic Artery Embolisation? - Springer Nature Link - November 2024
To compare the treatment and outcomes of blunt splenic injury (BSI) management strategy within Major Trauma centres in England between 2017 and 2022
To compare the treatment and outcomes of blunt splenic injury (BSI) management strategy within Major Trauma centres in England between 2017 and 2022
The ARMS-Hub Study – NIHR Open Research – October 2024
An alcohol-related liver disease multi-stakeholder hub to enhance research activity in underserved communities in the UK
An alcohol-related liver disease multi-stakeholder hub to enhance research activity in underserved communities in the UK
THE ALD Study – Nature Reviews Gastroenterology & Hepatology – October 2024
An expert panel Consensus Statement on ALD without experts by experience
An expert panel Consensus Statement on ALD without experts by experience
The MYRIAD Study – Cognition and Emotion – October 2024
Investigation of the mental health and cognitive correlates of psychological decentering in adolescence
Investigation of the mental health and cognitive correlates of psychological decentering in adolescence
The RESOLVE Study – Pilot and Feasibility Studies – September 2024
Protocol for a feasibility multi-centre randomised controlled trial of a pre-operative two-week very low-calorie diet to reduce steatosis prior to liver resection
Protocol for a feasibility multi-centre randomised controlled trial of a pre-operative two-week very low-calorie diet to reduce steatosis prior to liver resection
The cost of providing care by family and friends (informal care) in the last year of life: A population observational study - Palliative Medicine - July 2024
To estimate informal caregiving costs and explore the relationship with carer and decedent characteristics.
To estimate informal caregiving costs and explore the relationship with carer and decedent characteristics.
The ARMS-HUB Study - Lancet Gastroenterol & Hepatology - July 2024
Breaking down barriers between liver, addiction, and mental health services for people with alcohol-related liver disease
Breaking down barriers between liver, addiction, and mental health services for people with alcohol-related liver disease
The EDNA Study - Ophthalmology Retina - June 2024
Improved Structure and Function in Early-Detected Second-Eye Neovascular Age-Related Macular Degeneration: FASBAT/Early Detection of Neovascular Age-Related Macular Degeneration Report 1
Improved Structure and Function in Early-Detected Second-Eye Neovascular Age-Related Macular Degeneration: FASBAT/Early Detection of Neovascular Age-Related Macular Degeneration Report 1
The MATE Study - Acta Ophthalmol - May 2024
Treatment of age-related macular degeneration with aflibercept using a treat, extend and fixed protocol; A 4-year study of treatment outcomes, durability, safety and quality of life (An extension to the MATE randomised controlled trial)
Treatment of age-related macular degeneration with aflibercept using a treat, extend and fixed protocol; A 4-year study of treatment outcomes, durability, safety and quality of life (An extension to the MATE randomised controlled trial)
Place of death in Parkinson's disease and related disorders in England and Wales: post-pandemic trends and implications for care planning - Age and Ageing - March 2024
Review national and regional place of death trends for people with PDRD including pre- and post-pandemic trends.
Review national and regional place of death trends for people with PDRD including pre- and post-pandemic trends.
The MIRAGE Study – BMJ Open Gastroenterology – January 2024
Mental Imagery to Reduce Alcohol-related harm in patients with alcohol use disorder and alcohol-related liver damaGE: the MIRAGE randomised pilot trial results
Mental Imagery to Reduce Alcohol-related harm in patients with alcohol use disorder and alcohol-related liver damaGE: the MIRAGE randomised pilot trial results
The personal impact is considerable for family caregivers at the end-of-life – BMJ Supportive & Palliative Care
25 Family caregiver socio-economic status, access to palliative care and patients’ place of death: a health survey for England study
25 Family caregiver socio-economic status, access to palliative care and patients’ place of death: a health survey for England study
2023
The potential for medicinal cannabis to help manage challenging behaviour in people with intellectual disability: A perspective review – Sage Journals – November 2023
Around 2% of the population have intellectual disabilities. Over one-third people with intellectual disabilities (PwID) present with ‘challenging behaviour’, which nosologically and diagnostically is an abstract concept.
Around 2% of the population have intellectual disabilities. Over one-third people with intellectual disabilities (PwID) present with ‘challenging behaviour’, which nosologically and diagnostically is an abstract concept.
The Myriad Study – Journal of the American Academy of Child & Adolescent Psychiatry – October 2023
Student- and School-Level Factors Associated With Mental Health and Well-Being in Early Adolescence
Student- and School-Level Factors Associated With Mental Health and Well-Being in Early Adolescence
Treatment of age-related macular degeneration with aflibercept using a treat, extend and fixed protocol; A 4-year study of treatment outcomes, durability, safety and quality of life – Acta Ophthalmologica Journal – September 2023
The aim of this study was to provide outcomes, safety, durability and quality-of-life data with aflibercept using a modified treat, extend and fixed regime over 4 years.
The aim of this study was to provide outcomes, safety, durability and quality-of-life data with aflibercept using a modified treat, extend and fixed regime over 4 years.
Effectiveness of out-patient based acute heart failure care: a pilot randomised controlled trial – Acta Ophthalmologica Journal – September 2023
Acute heart failure (AHF) hospitalisation is associated with 10% mortality. Outpatient based management (OPM) of AHF appeared effective in observational studies. We conducted a pilot randomised controlled trial (RCT) comparing OPM with standard inpatient care (IPM).
Acute heart failure (AHF) hospitalisation is associated with 10% mortality. Outpatient based management (OPM) of AHF appeared effective in observational studies. We conducted a pilot randomised controlled trial (RCT) comparing OPM with standard inpatient care (IPM).
The D-PACT Study - BJGP Open - September 2023
Longitudinal realist evaluation of the Dementia PersonAlised Care Team (D-PACT) intervention: protocol
Longitudinal realist evaluation of the Dementia PersonAlised Care Team (D-PACT) intervention: protocol
A pilot examination of the validity of stylus and finger drawing on visuomotor-mediated tests on ACEmobile – Journal of Clinical and Experimental Neuropsychology – August 2023
The current study sought to test whether administering visuospatial and writing tests using a tablet (finger or stylus drawing), would demonstrate equivalence to traditional pencil and paper administration on ACEmobile.
The current study sought to test whether administering visuospatial and writing tests using a tablet (finger or stylus drawing), would demonstrate equivalence to traditional pencil and paper administration on ACEmobile.
Epilepsy in people with and without intellectual disabilities – Journal of Neurology – August 2023
Rapid switching from levetiracetam to brivaracetam in pharmaco-resistant epilepsy in people with and without intellectual disabilities: a naturalistic case control study
Rapid switching from levetiracetam to brivaracetam in pharmaco-resistant epilepsy in people with and without intellectual disabilities: a naturalistic case control study
The COVID-19 PD Study – Plus One – July 2023
Clinical features and outcomes of hospitalised patients with COVID-19 and Parkinsonian disorders: A multi-centre UK-based study
Clinical features and outcomes of hospitalised patients with COVID-19 and Parkinsonian disorders: A multi-centre UK-based study
The SSEP Study – Clinical Neurophysiology – July 2023
Enhanced analysis of somatosensory evoked potentials at 20–30 milliseconds can predict neurological outcome after cardiac arrest
Enhanced analysis of somatosensory evoked potentials at 20–30 milliseconds can predict neurological outcome after cardiac arrest
The e-coachER Study – Mental Health and Physical Activity – June 2023
Adding web-based support to exercise referral schemes improves symptoms of depression in people with elevated depressive symptoms: A secondary analysis of the e-coachER randomised controlled trial
Adding web-based support to exercise referral schemes improves symptoms of depression in people with elevated depressive symptoms: A secondary analysis of the e-coachER randomised controlled trial
The MATE study – Pilot and Feasibility Studies – April 2023
A multicentre, mixed-methodology, pilot, randomised controlled trial in neovascular age-related macular degeneration
A multicentre, mixed-methodology, pilot, randomised controlled trial in neovascular age-related macular degeneration
The PD Study - BMJ Open - March 2023
Impact of digital technologies on self-efficacy in people with Parkinson's: a scoping review protocol
Impact of digital technologies on self-efficacy in people with Parkinson's: a scoping review protocol
The TARS study – Addiction – March 2023
Effectiveness and cost-effectiveness of behavioural support for prolonged abstinence for smokers wishing to reduce but not quit: Randomised controlled trial of physical activity assisted reduction of smoking
Effectiveness and cost-effectiveness of behavioural support for prolonged abstinence for smokers wishing to reduce but not quit: Randomised controlled trial of physical activity assisted reduction of smoking
The Attachment Study – NIHR Journal – February 2023
Routinely used interventions to improve attachment in infants and young children: a national survey and two systematic reviews
Routinely used interventions to improve attachment in infants and young children: a national survey and two systematic reviews
The DIADS Study – International Journal of Environmental Research and Public Health – January 2023
Comparison of Diagnostic Profiles of Deaf and Hearing Children with a Diagnosis of Autism
Comparison of Diagnostic Profiles of Deaf and Hearing Children with a Diagnosis of Autism
2022
The PD-Stat Study – Jama Neurology – October 2022
Evaluation of Simvastatin as a Disease-Modifying Treatment for Patients With Parkinson Disease
Evaluation of Simvastatin as a Disease-Modifying Treatment for Patients With Parkinson Disease
The e-coachER Study – International Journal of Behavioral Nutrition and Physical Activity – September 2022
A process evaluation, with mediation analysis, of a web-based intervention to augment primary care exercise referral schemes: the e-coachER randomised controlled trial
A process evaluation, with mediation analysis, of a web-based intervention to augment primary care exercise referral schemes: the e-coachER randomised controlled trial
The ProGroup Study – National Library of Medicine – September 2022
A group-based behavioural intervention for weight management (PROGROUP) versus usual care in adults with severe obesity: a feasibility randomised controlled trial protocol
A group-based behavioural intervention for weight management (PROGROUP) versus usual care in adults with severe obesity: a feasibility randomised controlled trial protocol
The BREATHE Study – ERJ Open – August 2022
Mixed-methods feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness
Mixed-methods feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness
The EMaPP Study – BMJ Open – August 2022
Evaluating the Management of chronic Pelvic girdle Pain following pregnancy (EMaPP): study protocol for a randomised controlled feasibility trial to compare a customised pelvic orthosis with standard care
Evaluating the Management of chronic Pelvic girdle Pain following pregnancy (EMaPP): study protocol for a randomised controlled feasibility trial to compare a customised pelvic orthosis with standard care
The PD Stat Study – Journal of Parkinson's Disease – July 2022
Challenges of Incorporating Digital Health Technology Outcomes in a Clinical Trial: Experiences from PD STAT
Challenges of Incorporating Digital Health Technology Outcomes in a Clinical Trial: Experiences from PD STAT
The PD Stat Study – Journal of Parkinson's Disease – July 2022
Enhancing Trial Delivery in Parkinson’s Disease: Qualitative Insights from PD STAT
Enhancing Trial Delivery in Parkinson’s Disease: Qualitative Insights from PD STAT
The MIRAGE Study – BMJ Open – May 2022
Mental Imagery to Reduce Alcohol-related harm in patients with alcohol dependence and alcohol-related liver damaGE: the MIRAGE pilot trial protocol
Mental Imagery to Reduce Alcohol-related harm in patients with alcohol dependence and alcohol-related liver damaGE: the MIRAGE pilot trial protocol
The COVID-19 Study – JMIR Aging – April 2022
Implementing Affordable Socially Assistive Pet Robots in Care Homes Before and During the COVID-19 Pandemic: Stratified Cluster Randomized Controlled Trial and Mixed Methods Study
Implementing Affordable Socially Assistive Pet Robots in Care Homes Before and During the COVID-19 Pandemic: Stratified Cluster Randomized Controlled Trial and Mixed Methods Study
The SPIRES Study – Pilot and Feasibility Studies – March 2022
Functional standing frame programme early after severe sub-acute stroke (SPIRES): a randomised controlled feasibility trial
Functional standing frame programme early after severe sub-acute stroke (SPIRES): a randomised controlled feasibility trial
2021
The MaKKRO trial – Bone & Joint Open – November 2021
A randomized controlled trial comparing functional outcomes for navigated kinematically aligned total knee arthroplasty versus navigated mechanically aligned total knee arthroplasty
A randomized controlled trial comparing functional outcomes for navigated kinematically aligned total knee arthroplasty versus navigated mechanically aligned total knee arthroplasty
Mental Health Provision in UK Secondary Schools – MDPI – November 2021
Research reports high levels of mental health problems faced by young people in the UK. Schools provide a range of mental health support services, although these are often not robustly evaluated
Research reports high levels of mental health problems faced by young people in the UK. Schools provide a range of mental health support services, although these are often not robustly evaluated
Health risk behaviours among people with severe mental ill health during the COVID-19 pandemic – PLOS One – October 2021
Analysis of linked cohort data
Analysis of linked cohort data
The ADIR-Deaf Adaptation and the ADOS-2 Deaf Adaptation – Journal of Clinical Medicine – September 2021
Diagnosing Autism Spectrum Disorders in Deaf Children Using Two Standardised Assessment Instruments: The ADIR-Deaf Adaptation and the ADOS-2 Deaf Adaptation
Diagnosing Autism Spectrum Disorders in Deaf Children Using Two Standardised Assessment Instruments: The ADIR-Deaf Adaptation and the ADOS-2 Deaf Adaptation
The FLYBITE Study – Wellcome Open Research – June 2021
A clinical study to optimise a sand fly biting protocol for use in a controlled human infection model of cutaneous leishmaniasis
A clinical study to optimise a sand fly biting protocol for use in a controlled human infection model of cutaneous leishmaniasis
A mixed-method feasibility study of a novel transitional regime of incremental haemodialysis – Clinical and Experimental Nephrology – June 2021
Study design and protocol
Study design and protocol
The ENDURE Study – Clinical and Experimental Nephrology – June 2021
A mixed‑method feasibility study of a novel transitional regime of incremental haemodialysis: study design and protocol
A mixed‑method feasibility study of a novel transitional regime of incremental haemodialysis: study design and protocol
The Partners 2 Study – BJGP Open – May 2021
Evaluation of a primary care-based collaborative care model (PARTNERS2) for people with diagnoses of schizophrenia, bipolar, or other psychoses: study protocol for a cluster randomised controlled trial
Evaluation of a primary care-based collaborative care model (PARTNERS2) for people with diagnoses of schizophrenia, bipolar, or other psychoses: study protocol for a cluster randomised controlled trial
Ferric Derisomaltose (FDI) – BMC Nephrology – March 2021
A multi-centre prospective double blinded randomised controlled trial of intravenous iron (ferric Derisomaltose (FDI)) in Iron deficient but not anaemic patients with chronic kidney disease on functional status
A multi-centre prospective double blinded randomised controlled trial of intravenous iron (ferric Derisomaltose (FDI)) in Iron deficient but not anaemic patients with chronic kidney disease on functional status
The ADOS-2 Study – Journal of Autism and Developmental Disorders – March 2021
Adapting and validating the Autism Diagnostic Observation Schedule Version 2 for use with deaf children and young people
Adapting and validating the Autism Diagnostic Observation Schedule Version 2 for use with deaf children and young people
The CANDO Study – Brain, Behaviour, & Immunity - Health – February 2021
Assessment of Cytokines, microRNA and patient related outcome measures in Conversion Disorder/Functional Neurological Disorder (CD/FND): the CANDO clinical feasibility study
Assessment of Cytokines, microRNA and patient related outcome measures in Conversion Disorder/Functional Neurological Disorder (CD/FND): the CANDO clinical feasibility study
The MP Rapid 2019-NCOV Study – Sage Journals – February 2021
Evaluation of the MP Rapid 2019-NCOV IgM/IgG combo POCT test vs. an established platform-based method
Evaluation of the MP Rapid 2019-NCOV IgM/IgG combo POCT test vs. an established platform-based method
The NoPAC Study – Annals of Emergency Medicine – February 2021
The Use of Tranexamic Acid to Reduce the Need for Nasal Packing in Epistaxis (NoPAC): Randomized Controlled Trial
The Use of Tranexamic Acid to Reduce the Need for Nasal Packing in Epistaxis (NoPAC): Randomized Controlled Trial
The REACH-HF Study – NIHR Journals – February 2021
A facilitated home-based cardiac rehabilitation intervention for people with heart failure and their caregivers: a research programme including the REACH-HF RCT
A facilitated home-based cardiac rehabilitation intervention for people with heart failure and their caregivers: a research programme including the REACH-HF RCT
The EXPRESS Study – Annals of Clinical Biochemistry – February 2021
Evaluation of the MP Rapid 2019-NCOV IgM/IgG Combo POCT test vs an established platform-based method
Evaluation of the MP Rapid 2019-NCOV IgM/IgG Combo POCT test vs an established platform-based method
The PINS Study – The Bone & Joint Journal – February 2021
A prospective randomised clinical trial comparing a traditional versus an emollient skincare regimen for the care of pin-sites in patients with circular frames
A prospective randomised clinical trial comparing a traditional versus an emollient skincare regimen for the care of pin-sites in patients with circular frames
The NAT-C Study – January 2021
A cluster randomised trial of a Needs Assessment Tool for adult Cancer patients and their carers (NAT-C) in primary care: A feasibility study
A cluster randomised trial of a Needs Assessment Tool for adult Cancer patients and their carers (NAT-C) in primary care: A feasibility study
The SARS-CoV-2 Study – Clinical Medicine Journal – January 2021
Review of hygiene adaptations among UK doctors in controlling the spread of SARS-CoV-2 infection
Review of hygiene adaptations among UK doctors in controlling the spread of SARS-CoV-2 infection
The BRiMS Study – BMC – January 2021
Balance Right in Multiple Sclerosis (BRiMS): a feasibility randomised controlled trial of a falls prevention programme
Balance Right in Multiple Sclerosis (BRiMS): a feasibility randomised controlled trial of a falls prevention programme
2020
The TARS Study – BMJ Open – December 2020
Randomised controlled trial of tailored support to increase physical activity and reduce smoking in smokers not immediately ready to quit: protocol for the Trial of physical Activity-assisted Reduction of Smoking (TARS) Study
Randomised controlled trial of tailored support to increase physical activity and reduce smoking in smokers not immediately ready to quit: protocol for the Trial of physical Activity-assisted Reduction of Smoking (TARS) Study
The STEPS Study – Clinical Rehabilitation – December 2020
The effectiveness of peroneal nerve functional electrical simulation for the reduction of bradykinesia in Parkinson’s disease: A feasibility study for a randomised control trial
The effectiveness of peroneal nerve functional electrical simulation for the reduction of bradykinesia in Parkinson’s disease: A feasibility study for a randomised control trial
The SAFE Study – BMJ Open – December 2020
SAFE, a new therapeutic intervention for families of children with autism: a randomised controlled feasibility trial
SAFE, a new therapeutic intervention for families of children with autism: a randomised controlled feasibility trial
The e-coachER Study – NIHR Journals – November 2020
Adding web-based behavioural support to exercise referral schemes for inactive adults with chronic health conditions: the e-coachER RCT
Adding web-based behavioural support to exercise referral schemes for inactive adults with chronic health conditions: the e-coachER RCT
The e-coachER Study – British Journals of Sports Medicine – November 2020
Randomised controlled trial of an augmented exercise referral scheme using web-based behavioural support for inactive adults with chronic health conditions: the e-coachER trial
Randomised controlled trial of an augmented exercise referral scheme using web-based behavioural support for inactive adults with chronic health conditions: the e-coachER trial
The SUMS Study – BMJ Open – October 2020
“I’m in a very good frame of mind”: a qualitative exploration of the experience of standing frame use in people with progressive multiple sclerosis
“I’m in a very good frame of mind”: a qualitative exploration of the experience of standing frame use in people with progressive multiple sclerosis
The ASSSIST2 Study – BMC Psychology – June 2020
Autism Spectrum Social Stories In Schools Trial 2 (ASSSIST2): study protocol for a randomised controlled trial analysing clinical and cost-effectiveness of Social Stories™ in primary schools
Autism Spectrum Social Stories In Schools Trial 2 (ASSSIST2): study protocol for a randomised controlled trial analysing clinical and cost-effectiveness of Social Stories™ in primary schools
The LoDED Study – Heart – March 2020
Limit of detection of troponin discharge strategy versus usual care: randomised controlled trial
Limit of detection of troponin discharge strategy versus usual care: randomised controlled trial
2010 – 2019
The TACIT Study – Clinical Interventions in Aging – November 2019
Randomised Controlled Trial Of The Effect Of Tai Chi On Postural Balance Of People With Dementia
Randomised Controlled Trial Of The Effect Of Tai Chi On Postural Balance Of People With Dementia
The BREEZE-IPF – ERJ – October 2019
A feasibility, randomised controlled trial of a complex breathlessness intervention in idiopathic pulmonary fibrosis
A feasibility, randomised controlled trial of a complex breathlessness intervention in idiopathic pulmonary fibrosis
The TOPS-UK Study – BMJ Open – August 2019
Clinical and cost-effectiveness of teen online problem-solving for adolescents who have survived an acquired brain injury in the UK: protocol for a randomised, controlled feasibility study
Clinical and cost-effectiveness of teen online problem-solving for adolescents who have survived an acquired brain injury in the UK: protocol for a randomised, controlled feasibility study
The SUMS Study – The Lancet Neurology – July 2019
Assessment of a home-based standing frame programme in people with progressive multiple sclerosis (SUMS): a pragmatic, multi-centre, randomised, controlled trial and cost-effectiveness analysis
Assessment of a home-based standing frame programme in people with progressive multiple sclerosis (SUMS): a pragmatic, multi-centre, randomised, controlled trial and cost-effectiveness analysis
The BRiMS Study – NIHR Journals Library – June 2019
A self-management programme to reduce falls and improve safe mobility in people with secondary progressive MS: the BRiMS feasibility RCT
A self-management programme to reduce falls and improve safe mobility in people with secondary progressive MS: the BRiMS feasibility RCT
The HAPPI Study – Journal of Advanced Nursing – June 2019
The holistic assessment and care planning in partnership intervention study (HAPPI): A protocol for a feasibility, cluster randomized controlled trial
The holistic assessment and care planning in partnership intervention study (HAPPI): A protocol for a feasibility, cluster randomized controlled trial
The SAFE Study – BMJ Open – May 2019
SAFE, a new therapeutic intervention for families of children with autism: study protocol for a feasibility randomised controlled trial
SAFE, a new therapeutic intervention for families of children with autism: study protocol for a feasibility randomised controlled trial
The REACH-HF Study – European Journal of Preventive Cardiology – March 2019
The cost effectiveness of REACH-HF and home-based cardiac rehabilitation compared with the usual medical care for heart failure with reduced ejection fraction: A decision model-based analysis
The cost effectiveness of REACH-HF and home-based cardiac rehabilitation compared with the usual medical care for heart failure with reduced ejection fraction: A decision model-based analysis
The Heart of Stroke Study – BMJ Open – March 2019
HeART of Stroke: randomised controlled, parallel-arm, feasibility study of a community-based arts and health intervention plus usual care compared with usual care to increase psychological well-being in people following a stroke
HeART of Stroke: randomised controlled, parallel-arm, feasibility study of a community-based arts and health intervention plus usual care compared with usual care to increase psychological well-being in people following a stroke
The Sorafenib Study – Journal of Neurology, Neurosurgery & Psychiatry – February 2019
Phase 0 trial investigating the intratumoural concentration and activity of sorafenib in neurofibromatosis type 2
Phase 0 trial investigating the intratumoural concentration and activity of sorafenib in neurofibromatosis type 2
The NoPac Study – BMJ Open – February 2019
Novel use of tranexamic acid to reduce the need for Nasal Packing in Epistaxis (NoPac) randomised controlled trial: research protocol
Novel use of tranexamic acid to reduce the need for Nasal Packing in Epistaxis (NoPac) randomised controlled trial: research protocol
THE INSTEP Study – BMJ Open – January 2019
INSoles To Ease Pressure (INSTEP) Study: a multicentre, randomised controlled feasibility study to compare the effectiveness of a novel instant optimised insole with a standard insole for people with diabetic neuropathy: a study protocol
INSoles To Ease Pressure (INSTEP) Study: a multicentre, randomised controlled feasibility study to compare the effectiveness of a novel instant optimised insole with a standard insole for people with diabetic neuropathy: a study protocol
The TIC TOC Trial – BMJ Open – November 2018
Trial of intraoperative cell salvage versus transfusion in ovarian cancer (TIC TOC): protocol for a randomised controlled feasibility study
Trial of intraoperative cell salvage versus transfusion in ovarian cancer (TIC TOC): protocol for a randomised controlled feasibility study
The TACIT Trial – BMC Geriatrics – November 2018
A randomised controlled trial comparing the effectiveness of tai chi alongside usual care with usual care alone on the postural balance of community-dwelling people with dementia: protocol for the TACIT trial (TAi ChI for people with demenTia)
A randomised controlled trial comparing the effectiveness of tai chi alongside usual care with usual care alone on the postural balance of community-dwelling people with dementia: protocol for the TACIT trial (TAi ChI for people with demenTia)
The LoDED Trial – BMJ Open – October 2018
Randomised controlled trial of the Limit of Detection of Troponin and ECG Discharge (LoDED) strategy versus usual care in adult patients with chest pain attending the emergency department: study protocol
Randomised controlled trial of the Limit of Detection of Troponin and ECG Discharge (LoDED) strategy versus usual care in adult patients with chest pain attending the emergency department: study protocol
The PASTIES (chronic pain follow-up study) – Anaesthesia – October 2018
The impact of emergency department patient-controlled analgesia (PCA) on the incidence of chronic pain following trauma and non-traumatic abdominal pain
The impact of emergency department patient-controlled analgesia (PCA) on the incidence of chronic pain following trauma and non-traumatic abdominal pain
The REACH-HF Study – European Journal of Preventive Cardiology – October 2018
The effects and costs of home-based rehabilitation for heart failure with reduced ejection fraction: The REACH-HF multicentre randomized controlled trial
The effects and costs of home-based rehabilitation for heart failure with reduced ejection fraction: The REACH-HF multicentre randomized controlled trial
The e-coachER Trial – BMJ Open – September 2018
Multicentred randomised controlled trial of an augmented exercise referral scheme using web-based behavioural support in individuals with metabolic, musculoskeletal and mental health conditions: protocol for the e-coachER trial
Multicentred randomised controlled trial of an augmented exercise referral scheme using web-based behavioural support in individuals with metabolic, musculoskeletal and mental health conditions: protocol for the e-coachER trial
The STRENGTHEN Trial – BMJ Open – June 2018
Health trainer-led motivational intervention plus usual care for people under community supervision compared with usual care alone: a study protocol for a parallel-group pilot randomised controlled trial
Health trainer-led motivational intervention plus usual care for people under community supervision compared with usual care alone: a study protocol for a parallel-group pilot randomised controlled trial
The SPIRES Trial – Pilot and Feasibility Studies – March 2018
Standing Practice In Rehabilitation Early after Stroke (SPIRES): a functional standing frame programme (prolonged standing and repeated sit to stand) to improve function and quality of life and reduce neuromuscular impairment in people with severe sub-acute stroke - a protocol for a feasibility randomised controlled trial
Standing Practice In Rehabilitation Early after Stroke (SPIRES): a functional standing frame programme (prolonged standing and repeated sit to stand) to improve function and quality of life and reduce neuromuscular impairment in people with severe sub-acute stroke - a protocol for a feasibility randomised controlled trial
The REACH-HFpEF Pilot Study – BMJ Open – March 2018
A randomised controlled trial of a facilitated home-based rehabilitation intervention in patients with heart failure with preserved ejection fraction and their caregivers
A randomised controlled trial of a facilitated home-based rehabilitation intervention in patients with heart failure with preserved ejection fraction and their caregivers
The HeLP Trial – Paediatric Exercise Science – March 2018
Children's compliance with wrist worn accelerometry within a cluster randomised controlled trial: Findings from The Healthy Lifestyles Programme (HeLP)
Children's compliance with wrist worn accelerometry within a cluster randomised controlled trial: Findings from The Healthy Lifestyles Programme (HeLP)
The HeLP Trial – NIHR Journals Library – January 2018
Cluster randomised controlled trial and economic and process evaluation to determine the effectiveness and cost effectiveness of a novel intervention [Healthy Lifestyles Programme (HeLP)] to prevent obesity in school children
Cluster randomised controlled trial and economic and process evaluation to determine the effectiveness and cost effectiveness of a novel intervention [Healthy Lifestyles Programme (HeLP)] to prevent obesity in school children
The HeLP Trial – The Lancet Child & Adolescent Health – November 2017
Effectiveness of the Healthy Lifestyles Programme (HeLP) to prevent obesity in UK primary-school children: a cluster randomised controlled trial
Effectiveness of the Healthy Lifestyles Programme (HeLP) to prevent obesity in UK primary-school children: a cluster randomised controlled trial
The HeLP Trial – International Journal of Behavioral Nutrition and Physical Activity – November 2017
Intervention fidelity in the definitive cluster randomised controlled trial of the Healthy Lifestyles Programme (HeLP) trial: findings from the process evaluation
Intervention fidelity in the definitive cluster randomised controlled trial of the Healthy Lifestyles Programme (HeLP) trial: findings from the process evaluation
The STOPCUTS Trial – Pilot and Feasibility Studies – October 2017
Pilot parallel randomised controlled trial of protective socks against usual care to reduce skin tears in high risk people
Pilot parallel randomised controlled trial of protective socks against usual care to reduce skin tears in high risk people
Cost-effectiveness of screening for permanent hearing loss in children at school entry – BMJ Open – July 2017
A directly comparative two-gate case–control diagnostic accuracy study of the pure tone screen and HearCheck screener tests for identifying hearing impairment in school children
A directly comparative two-gate case–control diagnostic accuracy study of the pure tone screen and HearCheck screener tests for identifying hearing impairment in school children
The BRiMS Trial – Pilot and Feasibility Studies – July 2017
A guided self-management programme to reduce falls and improve quality of life, balance and mobility in people with secondary progressive multiple sclerosis: a protocol for a feasibility randomised controlled trial
A guided self-management programme to reduce falls and improve quality of life, balance and mobility in people with secondary progressive multiple sclerosis: a protocol for a feasibility randomised controlled trial
The DeCoDer Trial – NIHR Journals Library – June 2017
The data Debt Counselling for Depression in Primary Care: An Adaptive Randomised Controlled Pilot Trial
The data Debt Counselling for Depression in Primary Care: An Adaptive Randomised Controlled Pilot Trial
The PASTIES Trial – Association of Anaesthetists – May 2017
The cost‐effectiveness of patient‐controlled analgesia vs. standard care in patients presenting to the Emergency Department in pain, who are subsequently admitted to hospital
The cost‐effectiveness of patient‐controlled analgesia vs. standard care in patients presenting to the Emergency Department in pain, who are subsequently admitted to hospital
The HeLP Trial – BMC Public Health – April 2017
Trial baseline characteristics of a cluster randomised controlled trial of a school-located obesity prevention programme; the Healthy Lifestyles Programme (HeLP) trial
Trial baseline characteristics of a cluster randomised controlled trial of a school-located obesity prevention programme; the Healthy Lifestyles Programme (HeLP) trial
The DIAT Trial – BMJ Open – March 2017
A pre-consultation web-based tool to generate an agenda for discussion in diabetes outpatient clinics to improve patient outcomes (DIAT): a feasibility study
A pre-consultation web-based tool to generate an agenda for discussion in diabetes outpatient clinics to improve patient outcomes (DIAT): a feasibility study
The HeLP Trial – BMC Public Health – December 2016
Detailed statistical analysis plan for a cluster randomised controlled trial of the Healthy Lifestyles Programme (HeLP), a novel school-based intervention to prevent obesity in school children
Detailed statistical analysis plan for a cluster randomised controlled trial of the Healthy Lifestyles Programme (HeLP), a novel school-based intervention to prevent obesity in school children
The HeLP Trial – Trials – December 2016
Detailed statistical analysis plan for a cluster randomised controlled trial of the Healthy Lifestyles Programme (HeLP), a novel school-based intervention to prevent obesity in school children
Detailed statistical analysis plan for a cluster randomised controlled trial of the Healthy Lifestyles Programme (HeLP), a novel school-based intervention to prevent obesity in school children
The REACH-HFpEF Trial – BMJ Open – October 2016
Rehabilitation Enablement in Chronic Heart Failure - a facilitated self-care rehabilitation intervention in patients with heart failure with preserved ejection fraction (REACH-HFpEF) and their caregivers: rationale and protocol for a single-centre pilot randomised controlled trial
Rehabilitation Enablement in Chronic Heart Failure - a facilitated self-care rehabilitation intervention in patients with heart failure with preserved ejection fraction (REACH-HFpEF) and their caregivers: rationale and protocol for a single-centre pilot randomised controlled trial
The SUMS Trial – BMC Neurology – May 2016
Standing up in multiple sclerosis (SUMS): protocol for a multi-centre randomised controlled trial evaluating the clinical and cost effectiveness of a home-based self-management standing frame programme in people with progressive multiple sclerosis
Standing up in multiple sclerosis (SUMS): protocol for a multi-centre randomised controlled trial evaluating the clinical and cost effectiveness of a home-based self-management standing frame programme in people with progressive multiple sclerosis
The SES Trial – NIHR Journals Library – May 2016
A programme of studies including assessment of diagnostic accuracy of school hearing screening tests and a cost-effectiveness model of school entry hearing screening programmes
A programme of studies including assessment of diagnostic accuracy of school hearing screening tests and a cost-effectiveness model of school entry hearing screening programmes
The TWIST Trial – Clinical Rehabilitation – February 2016
Does the use of Nintendo Wii SportsTM improve arm function? Trial of WiiTM in Stroke: A randomised controlled trial and economics analysis
Does the use of Nintendo Wii SportsTM improve arm function? Trial of WiiTM in Stroke: A randomised controlled trial and economics analysis
The Scrutiknee Trial – Pilot and Feasibility Studies – February 2016
Western medical acupuncture in a group setting for knee osteoarthritis: results of a pilot randomised controlled trial
Western medical acupuncture in a group setting for knee osteoarthritis: results of a pilot randomised controlled trial
The REACH-HF Trial – Chronic Illness – December 2015
Needs of caregivers in heart failure management: A qualitative study
Needs of caregivers in heart failure management: A qualitative study
The REACH HF Trial – BMJ Open – December 2015
Clinical effectiveness and cost-effectiveness of the Rehabilitation Enablement in Chronic Heart Failure (REACH-HF) facilitated self-care rehabilitation intervention in heart failure patients and caregivers: rationale and protocol for a multicentre randomised controlled trial
Clinical effectiveness and cost-effectiveness of the Rehabilitation Enablement in Chronic Heart Failure (REACH-HF) facilitated self-care rehabilitation intervention in heart failure patients and caregivers: rationale and protocol for a multicentre randomised controlled trial
The REVERT Trial – The Lancet – August 2015
Postural modification to the standard Valsalva manoeuvre for emergency treatment of supraventricular tachycardias (REVERT): a randomised controlled trial
Postural modification to the standard Valsalva manoeuvre for emergency treatment of supraventricular tachycardias (REVERT): a randomised controlled trial
The STOPCUTS Trial – Pilot and Feasibility Studies – June 2015
Pilot randomised controlled trial of protective socks against usual care to reduce skin tears in high risk people "STOPCUTS": study protocol
Pilot randomised controlled trial of protective socks against usual care to reduce skin tears in high risk people "STOPCUTS": study protocol
The PASTIES Trial – British Medical Journal – May 2015
PAin SoluTions In the Emergency Setting (PASTIES) - patient controlled analgesia versus routine care in emergency department patients with pain from traumatic injuries: randomised trial
PAin SoluTions In the Emergency Setting (PASTIES) - patient controlled analgesia versus routine care in emergency department patients with pain from traumatic injuries: randomised trial
The PASTIES Trial – British Medical Journal – April 2015
PAin SoluTions In the Emergency Setting (PASTIES) - patient controlled analgesia versus routine care in emergency department patients with non-traumatic abdominal pain: randomised trial
PAin SoluTions In the Emergency Setting (PASTIES) - patient controlled analgesia versus routine care in emergency department patients with non-traumatic abdominal pain: randomised trial
The TWIST Trial – Clinical Rehabilitation – March 2015
Participant and caregiver experience of the Nintendo Wii SportsTM after stroke: qualitative study of the trial of WiiTM in stroke (TWIST)
Participant and caregiver experience of the Nintendo Wii SportsTM after stroke: qualitative study of the trial of WiiTM in stroke (TWIST)
The CUPID Trial – NIHR Journals Library – February 2015
The Cannabinoid Use in Progressive Inflammatory brain Disease (CUPID) trial: a randomised double-blind placebo-controlled parallel-group multicentre trial and economic evaluation of cannabinoids to slow progression in multiple sclerosis
The Cannabinoid Use in Progressive Inflammatory brain Disease (CUPID) trial: a randomised double-blind placebo-controlled parallel-group multicentre trial and economic evaluation of cannabinoids to slow progression in multiple sclerosis
The SUBLIME Trial – BMJ Open – January 2015
Study protocol for a double blind, randomised, placebo-controlled trial of continuous subpectoral local anaesthetic infusion for pain and shoulder function following mastectomy: SUB-pectoral Local anaesthetic Infusion following Mastectomy (SUBLIME) study
Study protocol for a double blind, randomised, placebo-controlled trial of continuous subpectoral local anaesthetic infusion for pain and shoulder function following mastectomy: SUB-pectoral Local anaesthetic Infusion following Mastectomy (SUBLIME) study
The TWIST Trial – International Journal of General Medicine – October 2014
Does the use of Nintendo Wii SportsTM improve arm function and is it acceptable to patients after stroke? Publication of the Protocol of the Trial of WiiTM in Stroke – TWIST
Does the use of Nintendo Wii SportsTM improve arm function and is it acceptable to patients after stroke? Publication of the Protocol of the Trial of WiiTM in Stroke – TWIST
The CUPID Trial – Lancet Neurology – September 2013
Effect of dronabinol on progression in progressive multiple sclerosis (CUPID): a randomised, placebo-controlled trial
Effect of dronabinol on progression in progressive multiple sclerosis (CUPID): a randomised, placebo-controlled trial
The DIAT Trial – BMJ Open – June 2013
A pilot randomised controlled trial of a preconsultation web-based intervention to improve the care quality and clinical outcomes of diabetes outpatients (DIAT)
A pilot randomised controlled trial of a preconsultation web-based intervention to improve the care quality and clinical outcomes of diabetes outpatients (DIAT)
The HeLP Trial – Trials – April 2013
The Healthy Lifestyles Programme (HeLP), a novel school-based intervention to prevent obesity in school children: study protocol for a randomised controlled trial
The Healthy Lifestyles Programme (HeLP), a novel school-based intervention to prevent obesity in school children: study protocol for a randomised controlled trial
The PASTIES Trial – BMJ Open – January 2013
Pain Solutions In the Emergency Setting (PASTIES); a protocol for two open-label randomised trials of patient-controlled analgesia (PCA) versus routine care in the emergency department
Pain Solutions In the Emergency Setting (PASTIES); a protocol for two open-label randomised trials of patient-controlled analgesia (PCA) versus routine care in the emergency department
The South West Impact of Multiple Sclerosis (SWIMS) Trial – BMC Neurology – October 2010
Patient-orientated longitudinal study of multiple sclerosis in south west England (The South West Impact of Multiple Sclerosis Project, SWIMS) 1: protocol and baseline characteristics of cohort
Patient-orientated longitudinal study of multiple sclerosis in south west England (The South West Impact of Multiple Sclerosis Project, SWIMS) 1: protocol and baseline characteristics of cohort
