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Awadhesh Jha

 

Personal photograph uploaded by Awadhesh Jha

Professor Awadhesh Jha

  • Job title: Professor, School of Biomedical and Biological Sciences (Faculty of Science and Technology)
  • Address: Room 407, Davy Building, Drake Circus,
    Plymouth, Devon, PL4 8AA
  • Postal address: Room 407, Davy Building, Drake Circus, Plymouth, Devon, PL4 8AA
  • Telephone: +44 (0)1752 584633
  • Alternative telephone: +44 (0)1752 584604
  • Facsimile: +44 (0)1752 584605
  • Email: A.Jha@plymouth.ac.uk


Role

Awadhesh N. Jha

Professor of Genetic Toxicology & Ecotoxicology
School of Biomedical & Biological Sciences
Post Graduate Research Coordinator and Tutor

Module Leader:
Ecotoxicology (Undergraduate programme)
Cellular & Molecualr Toxicology (Master's Programme) Pollution Ecology & Ecotoxicology (Master's Programme) Advanced Techniques in Aquatic Biology (Master's Programme)

University Harassment Advisor
Member, University Equality and Diversity Committee

 

Qualifications & background

ACADEMIC QUALIFICATIONS:

1989:PhD – “Ionising radiations and chromosome aberrations: a study using peripheral blood lymphocyte culture system in human” sponsored by International Atomic Energy Agency, Vienna (Austria) and Dept. of Atomic Energy, Bombay (India), Banaras Hindu University, India

1981:MSc (1st class) in Zoology with specialisation in Cytogenetics, Bhagalpur University, India

1979:BSc (1st Class Honours) in Zoology with Botany and Chemistry, Bhagalpur University, India

PROFESSIONAL QUALIFICATIONS:

1998:Accreditation as a Teacher in Higher Education following successful completion of the Staff and Educational Development Association (SEDA), UK recognised programme at the University of Plymouth, UK 1997:Certificate in Teaching and Learning in Higher Education, Academic Services, University of Plymouth, UK 1993:Home Office (UK) Training Course for Animals (Scientific Procedure Act, 1986), Brixham Environmental Laboratory, AstraZeneca, Brixham, Devon, UK (personal licence holder)
1983:Certificate following course on “Safety aspects in the research applications of ionising radiations” Bhabha Atomic Research Centre, Bombay, India

APPOINTMENTS / PROFESSIONAL EXPERIENCE:


2010-till date: Professor, School of Biomedical & Biological Sciences, University of Plymouth, UK
2005-2010: Reader, School Biological Sciences,University of Plymouth, Plymouth, UK
2001- 2005: Principal Lecturer,  School Biological Sciences, University of Plymouth, Plymouth, UK
1998-2001: Senior Lecturer, Dept. of Biological Sciences, University of Plymouth, Plymouth, UK
1996-1998:ZENECA Lectureship in Marine Genotoxicity, University of Plymouth, UK
1993-1996: Marine Genetic Toxicologist, Brixham Environmental Laboratory, AstraZeneca (formerly Zeneca and ICI, UK), Brixham, Devon, UK
1990-1993:Post-doctoral Research Fellow, Department of Radiation Genetics and Chemical Mutagenesis, University of Leiden, The Netherlands
1989-1990:Research Associate (post-doctoral) supported by University Grants Commission, New Delhi, at Banaras Hindu University, India
1981-1989:Junior and Senior Research Fellows, Research Assistant, Centre of Advanced Study in Zoology, Banaras Hindu University, India

 

Professional membership
Member, Natural Environment Research Council (NERC), UK: Peer Review College
Member,Scientific / Organising Committee (10 membered):European Environmental Mutagen Society 2002-2003 (to Organise the 33rd Annual Meeting of the European Environmental Mutagen Society in August 2003 at Aberdeen)
Chair, Scientific Committee, United Kingdom Environmental Mutagen Society (UKEMS): 2001-2002; Member, Executive Committee, UKEMS (2010-2013)
Member, United Kingdom (UK) and European Environmental Mutagen Society (UKEMS, EEMS) Member, Industrial Genotoxicology Group (IGG), UK
Founding Member, International Network on the Research in Eco-genotoxicology (INREG) (based in Roskilde, University, Denmark)
Member, Coordinating Group on Environmental Radioactivity (COGER), UK
Life Member and Member, Executive Committee (2009-2011), Indian Society of Cell Biology 

Roles on external bodies


Journal Editing and Editorial Board Membership (since 2000):

Edited, Special Issue of Mutation Research (Fundamental and Molecular Mechanisms of the Mutagenesis): 'Use of Aquatic Organisms in Genotoxicological Studies' Vol. 5552, August, 2004
Co-edited, Special Issue of Marine Environmental Research: Pollutant Response in Marine Organisms
PRIMO 11 Symposium) (Vol. 54, 2002)
Member, Editorial Board of the International Journal- Mutation Research (Fundamental & Molecular Mechanisms of Mutagenesis): 1997-2002(Elsevier Science)
Member, Editorial Board of the International Journal- the Science of the Total Environment: 2002-2006 (Elsevier Science)
Member, Editorial Board of the International Journal-Ecotoxicology: 2005-onwards (Springer Science)
Member, Editorial Board of the International Journal- Mutation Research (Genetic Toxicology & Environmental Mutagenesis): 2006-onwards (Elsevier Science) 

Reviewer for the International Journals:

(* Regular reviewer)

Analytica Chimica Acta, Aquatic Toxicology, Biochimica Et Biophysica Acta, Biomarkers, Chemical Biological Interactions, Chemosphere, *Ecotoxicology, Environment International, Environmental Pollution, Environmental Toxicology, Environmental Toxicology and Chemistry, Estuarine Coastal  and Shelf Sciences, Journal of Sea Research, Journal of Fish Biology, Journal of Marine Biological Association of the UK *Marine Environmental Research, Marine Biology, *The Science of the Total Environment, Marine Pollution Bulletin, *Mutagenesis, *Mutation Research, etc.

Reviewer for Research Grant Proposal:

Natural Environmental Research Council (NERC), UK
Member, NERC Peer-Review College (2006-2010), UK
Biotechnology & Biological Sciences Reserach Council (BBSRC), UK
Engineering & Physical Sciences Research Council (EPSRC), UK
The Royal Society, UK
National Science Foundation (NSF), USA
Italian Ministry for Education University and Research (MIUR), Italy
Portuguese Ministry of Science & Technology, Lisbon, Portugal
British Council, UK
Wellcome Trust, UK

 


Teaching interests

Genetics, Molecular & Cellular Response to the Environment

Aspects of Genetics and Toxicology including Genetic Toxicology and Carcinogenesis, Ecotoxicology, Environmental Pollution,  Aspects of Mutagenesis and Carcinogenesis (also for Medical Students under Special Study Unit Programme of Penninula Medical School); Research Methods & Techniques for under- and post-graduates 

 

Staff serving as external examiners

Post-Graduate (PhD) Examinership:

University of Plymouth (Internal Examiner)
Peninsula College of Medicine & Dentistry (PCMD), UK 

University of Birmingham, UK

University of East Anglia, UK
University of Newcastle, UK
University of Portsmouth, UK
University of Southampton, UK
University of Sussex, UK
University of Ulster, UK

University of Nantes, Ifremer, France
University of Metz/ Lyon, France
Aligarh Muslim University, India 


(Declined several examinership offers from overseas)

 


Research interests

General Description:

My background with respect to research interest and experience is reflected in academic / professional qualificationss and the publication list. These reflect my interest and experience in classical, molecular and clinical cytogenetics, radiation cytogenetics, molecular genetics, chemical mutagenesis, environmental biomonitoring, eco-genotoxicology and ecotoxicology.

Member: Ecotoxicology & Stress Biology Research Group

Key Research Accomplishments:

• Contribution to fundamental and molecular mechanisms of mutagenesis with respect to human and ecosystem health
• Development and applications of assays to evaluate genotoxicity, cytotoxicity and ecotoxicity (at different levels of biological organisation) in the aquatic organisms/ environment
•Ecological hazard and risk assessment
•Contribution to applied and promotion of multidisciplinary research

Recent Research Grants (since 2000):

Short Title- Sponsor- Year

1. Development of the strategies to assess the impact of radioactive effluent discharge on the marine invertebrates (special CASE award)-NERC, EA, DML-1998-2001
2. Impact of ionising radiation on aquatic invertebrates in the Chernobyl zone(in collaboration with CEH, Dorset) -NERC-2002-2005
3. In Vitro investigation of the interactive toxic effects of UV radiation (in collaboration with Cornwall College, Cornwall Dermatology Unit, Peninsula Medical School)Duchy Health Charity-2003-2006
4. Ecotoxicological impact of chemical contaminants on aquatic organisms- Assoc. CW Uni.-2003-2003
5. Development of Biomarkers using Echinoderms (with Prof. Malcolm Jones)- Industrial CASE Award (in collaboration with AstraZeneca)- NERC-2004-2007
6. Trace element enhancement of ornamental fish diets to minimise oxidative stress and genomic instability (with Dr. Simon Davies)- Waltham Centre for Pet nutrition, Mars; 2004-2007
7. Role of dietary selenium and zinc in promotion of fish nutrition and health (with Dr.Simon Davies)- BBSRC-ALLTECH CASE Studentship; 2005-2008
8. Impact of ionising radiations on aquatic organisms, International Atomic Energy Agency (IAEA), Vienna; 2008-2011
9. Mechanistic Application of Spheroids Cell Culture to 3Rs in Fish Ecotoxicology; BBSRC-CASE Award with AstraZeneca; 2010-2014 (PI). 
10. Applications of tissue culture in toxicology; Republic of Iraq Research Fellowship; 2010-1014 (PI)
11. Consequences of chronic exposure of marine species to low concentrations of pollutants Funding: European Commission (INTERREG) 

 

UoP Research group membership

Centre for Research in Translational Biomedicine (CRTB) 
Ecotoxicology Research & Innovation Centre (ERIC) 

Other research

Scientific Exchange Programme (since 2000):

British Council Sponsored (funded)Exchange Programme with University of Vienna, Austria, 2004-2005 Sponsored by DTI, UK; member of official 4 membered-UK team Radioecology of Chornobyl Zone, International Conference in Slavutych, Ukraine, September 17-19, 2002
British Council Sponsored Exchange Programme with University of Malaya, Malaysia, March-April 2002. Association of Commonwealth Universities Exchange Programme with Jamia Hamdard University, Delhi, India, January 2003-July 2003. (grant sanctioned to host visiting scientist)
Sponsored by DTI, UK; member of official 6 membered-UK team, Technical and Social Aspects of Chernobyl NPP Closure, Slavutych, Ukraine, September 26-29, 2000


Invited Course Instructor / Lecturer (Since 2000):

(** Fully Sponsored, Paid; * Partially Sponsored, Paid)

Genotoxicity assays, Medical University, Vienna, Austria, June 2006 
** Convenor, Workshop on Applications of Biomarkers to Protect Human and Ecosystem Health; Banaras Hindu University, India; Workshop to be Sponsored by Royal Society, UK and the Department of Science and Technology, India (to be organised in September 2004; involves colleagues from University of Plymouth, Plymouth Marine Laboratory and University of Leeds)
**Instructor & Lecturer, Workshop in Marine Biomonitoring, Asia-pacific Conference on Marine Science and Technology, Kuala Lumpur, Malaysia, May 2002
**Course Director and Instructor, Advanced Techniques in Aquatic Toxicology, Prior to 11th Symposium on Pollutant Response in Marine Organisms (PRIMO 11 symposium) at the University of Plymouth for 3 days, July 2001, Plymouth, UK (participated by 35 delegates from all over the world)

 

Participations / Presentations in National & International Conferences / Workshops (since 2000):

(** Fully Sponsored; * Partially Sponsored)

**SETACK UK, Human and Environmental Health, (invited lecture), London, UK, September 2009
VI International Comet Assay Workshop, Warsaw, Poland, September 2005
Invited Research Talk, University of Patna, Patna, India, August 2005
Invited Research Talk, University of Bhagalpur, India, August 2005 
Coordinating Group on Environmental Radioactivity (COGER), 24th Annual Open Meeting, University of Bristol, UK, April 2005 (Oral-by PhD student)
Estuarine and Coastal Sciences Association (ECSA) Symposium, Univ. Plymouth, UK, April 2005 (Oral Presentation)
*Coordinating Group on Environmental Radioactivity (COGER), 23rd Annual Open Meeting, University of Liverpool, UK, April 2004 (Oral-by student and 2 Poster Presentations)
5th International Workshop on Comet Assay, Aberdeen, UK, August 2003
**Coordinating Group on Environmental Radioactivity (COGER), 23rd Annual Open Meeting, Lancaster University, UK, April 2003 (Oral and Poster Presentations)
**Radioecology of Chernobyl Zone, International Conference in Slavutych, Ukraine, September 17-19, 2002; Member of a 4 membered UK delegate sponsored by DTI, UK)
**Annual meeting of the NERC sponsored Coordinating Group on Environmental Radioactivity (COGER), Imperial College London, London, UK, September 2001. (Oral & Poster Presentations)
**Workshop on UK-Japan Co-operation Research on Endocrine Disrupters in the Aquatic Environment, January 29-30, 2001, University of Plymouth, Plymouth, UK (Sponsored by DETR, UK; Invited Participation)
*4th Annual Conference, International Chernobyl Centre, Scientific, Technical and Social Aspects of Chernobyl NPP Closure, Slavutych, Ukraine, September 26-29, 2000 (Invited participation, sponsored by DTI, UK; member of official 6 membered-UK team)
**Annual meeting of the NERC sponsored Coordinating Group in Environmental Radioactivity (COGER), University of Southampton, Southampton, UK, September 2000. (Oral Presentation)
24th Annual Scientific Meeting of the United Kingdom Environmental Mutagen Society, (UKEMS), University of Wales, Swansea, UK, July 2000 (Poster Presentations)

 

Research degrees awarded to supervised students

1. PhD Completion as Director of Studies (first supervisor): 8

Franck  Atienzar (2000): Development of the random amplified polymorphic DNA (RAPD) technique to measure the effects of genotoxins in aquatic organisms (Funded by EU Marie Curie Grant)
Philip  Pascoe
(2002):Chromosomal variation in Nucella lapillus (L.) and other muricid gastropods (Funded by Plymouth Marine Laboratory)
Josephine  Hagger
(2003):Evaluation of radionuclide-induced damage in marine invertebrates (Funded by NERC, EA and Devonport Royal Dockyard Ltd., Special CASE Award)
Victoria  Cheung
(2003):Detection of genetic toxicity in marine invertebrates (Funded by DETR and Univ. of Plymouth)
Claire Cailes
(2007):Impact of ionising radiations in freshwater invertebrates (in collaboration with CEH Dorset; Drs. Jim Smith & John Murphy) (Funded by NERC)
Zoë Lyle (2008):Interactive toxic effects of UV radiation and PAHs (in collaboration with PMS and Cornwall College : Drs. Alison Curnow and Leo Salter) (Funded by the Duchy Health Charity & Penninsula Medical School)
Martin Canty (2010): Echinoderms and marine pollution: Development of non-destructive biomarkers (Other Supervisors: Prof. MB Jones; Dr. R Brown; Dr. T Hutchinson; Funding: NERC CASE Award with AstraZeneca) 
Sherain Al-Subiai (2007-10): Impact of PAHs on aquatic invertebrates (with Dr. A. John Moody) (Funded by State of Kuwait)  

2. PhD Completion as Co Supervisor: 4 

Saravuth Rattanachongkiat (2000-2004): Distribution and speciation of arsenic in the Pale Pa-Nang estuary (With Dr. Mike Foulkes and Prof. Geoff Millward, School of Earth, Ocean and Environmental Sciences, University of Plymouth) (Funded by the Govt. of Thailand)
Catherine Money (2003-2006) Metal speciation and Toxicity (in Collaboartion with Drs. Charlotte Braungardt, Eric eictenberg and Prof. Paul Worsford) (Funded by NERC; CASE Award)
James Reeves (2004-2007): Role of micronutrients and environmental agents for the induction of oxidative damage in relation to fish health (with Dr. Simon Davies) (Funded by Waltham Pet Care, Mars) 
 Sebastien Rider (2005-2008): Role of dietary selenium and zinc in promotion of fish nutrition and health (with Dr. Simon Davies) (Funded by BBSRC and Alltech)

3. PhD In Progress as Director of Studies: 5

Sanna Abdul Mustafa (2007-11): Impact of pollutnats on frshwater fish (with Dr. Simon Davies) (Funded by Republic of Iraq Govt.)
Yanan Di (2008-12) Invertebrate ecotoxicology (with Drs. Declan Schroeder-MBA and Murray Brown-UoP) (Funded by ORS).
Helena Reinardy (2008-11) Impact of ionising radiations on aquatic organisms (with Drs. Ted Henry-UoP; Bill Langsdon-MBA and Ross Jeffree-IAEA, MEL, Monaco). (Funded by Marine Institute and IAEA, Vienna).  
Matthew Baron (2010-13) Mechanistic Application of Spheroids Cell Culture to 3Rs in Fish Ecotoxicology (Co-Supervisors:  Profs. W Purcell, S Jackson and Dr. S Owen; Funding: BBSRC CASE award with AstraZeneca)
Lorna Dallas (2010-13) Consequences of chronic exposure of marine species to low concentrations of pollutants; (Co-supervisors: Drs. Miranda Keith-Roach and Brett Lyons, CEFAS, Weymouth; Funding: European Commission; INTERREG)

4. PhD In Progress as Co-Supervisor: 3 

Alexandros Samartzis (2007-2011): Trace element nutrition and toxicity in sea brim  (with Dr. Simon Davies) (Govt. of Greece)
Arafat Ahmed (2007-2011) Food, nutrion and toxicity in larvae of marine fish species (with Dr. Simon Davies) (Govt. of Republic of Iraq)
Samad Omar (2008-2011) Development of sustainable diets for carp based on novel industrial by-products (with Dr. Simon Davies)
 

Grants & contracts

Recent Research Grants (since 2000):

Short Title- Sponsor- Year

1. Development of the strategies to assess the impact of radioactive effluent discharge on the marine invertebrates (special CASE award)-NERC, EA, DML-1998-2001
2. Impact of ionising radiation on aquatic invertebrates in the Chernobyl zone(in collaboration with CEH, Dorset) -NERC-2002-2005
3. In Vitro investigation of the interactive toxic effects of UV radiation (in collaboration with Cornwall College, Cornwall Dermatology Unit, Peninsula Medical School)Duchy Health Charity-2003-2006
4. Ecotoxicological impact of chemical contaminants on aquatic organisms- Assoc. CW Uni.-2003-2003 5. Development of Biomarkers using Echinoderms (with Prof. Malcolm Jones)- Industrial CASE Award (in collaboration with AstraZeneca)- NERC-2004-2007
6. Trace element enhancement of ornamental fish diets to minimise oxidative stress and genomic instability (with Dr. Simon Davies)- Waltham Centre for Pet nutrition, Mars; 2004-2007
7. Role of dietary selenium and zinc in promotion of fish nutrition and health (with Dr.Simon Davies)- BBSRC-ALLTECH CASE Studentship; 2005-2008
8. Assessing the impact of polyaromatic hydrocarbons in marine invertebrates. Govt. of Kuwait, Research Studentship; 2007-2010
9. Impact of contaminants on fish: toxicological and pathological approach. Republic of Iraq, Research Studentship. 2007-2011
10. Impact of Ionising raditions on aquatic organisms; UoP and IAEA, Vienna; 2008-2011.
11. Consequences of chronic exposure of marine species to low concentrations of pollutants; European Commission
(INTERREG IV A). 2009-14. (PI)
12. Mechanistic Application of Spheroids Cell Culture to 3Rs in Fish Ecotoxicology; BBSRC-CASE Award with AstraZeneca; 2010-2013 (PI).
13. Applications of tissue culture in toxicology; 2010-14;  Republic of Iraq Research   Fellowship.  

 

Creative practice & artistic projects

Contribution to the Public Understanding of Science; Wider Dissemination of Activities:

Newspaper articles and interviews

Articles in relation to research activities and for the interest of general public and colleagues

Participation and listed for BBC Radio (e.g. 5 Live, BBC World Service, Ulster, West Country, Scotland etc.) and local TV channels on current issues

 


Publications

Published papers (since 2000):

(Citations based on SCOPUS)

1.  Di Y, DC Schroeder, A Highfield, JW Readman, AN Jha (2011) Tissue specific expression of P53 and ras genes in response to the environmental genotoxicants Benzo(a)pyrene in marine mussels. Environmental Science and Technology 45, 8974-8981. (IF: 4.825).
2.  Al-Subiai SN, AJ Moody, SA Mustafa, AN Jha (2011) A multiple biomarker approach to investigate the effects of copper on the marine bivalve mollusc, Mytilus edulis. Ecotoxicology & Environmental Safety 74, 1913-1920. (IF: 2.340).
3.  Reinardy HC, J-L Teyssie, RA Jeffree, D Copplestone, TB Henry, AN Jha (2011) Uptake, depuration, and radiation dose estimation in zebrafish exposed to radionuclides via aqueous or dietary routes. The Science of the Total Environment 409, 3771-3779. (IF: 2.905)
4.  Mustafa SA, SN Al-Subiai, SJ Davies, AN Jha (2011) Hypoxia-induced oxidative DNA damage links with higher level biological effects including specific growth rate in common carp, Cyprinus carpio L. Ecotoxicology 20, 1455-1466 (IF: 3.507).
5.  Kadar E, GA Tarran, AN Jha, SN Al-Subiai (2011) Stablisation of engineered zerovalent nanoiron with Na-acrylic copolymer enhances spermiotoxicity. Environmental Science and Technology 45, 3245-3251 (IF: 4.825).
6.   Dodd NJF, AN Jha (2011) The photoexcitation of aqueous suspensions of titanium dioxide nanoparticles: an electron spin resonance (ESR) spin trapping study of potentially oxidative reactions. Photochemistry & Photobiology 87, 632-640. (IF: 2. 253).
7.  Money C, CB Braungardt, AN Jha, PJ Worsfold, EP Achterberg (2011) Metal speciation and toxicity of Tamar Estuary water to larvae of the Pacific oyster, Crassostrea gigas. Marine Environmental Research 72, 3-12(IF-1.755).
8. Papis E, SJ Davies, AN Jha (2011) Relative sensitivity of fish and mammalian cells to antibiotic, trimethoprim: cytotoxic and genotoxic responses as determined by neutral red retention, comet and micronucleus assays. Ecotoxicology 20, 208-217 (IF: 3.507).
9.  Jaeschke BC, GE Millward, AJ Moody, AN Jha (2011) Tissue-specific incorporation and genotoxicity of different forms of tritium in the marine mussel, Mytilus edulis. Environmental Pollution 159, 274-280 (IF: 3.426).

10.   Kadar E, D Lowe, M Sole, AS Fisher, AN Jha, JW Readman, TH Hutchinson (2010) Uptake and biological responses to nano-Fe versus soluble FeCl3 in excised mussel gills. Analytical and Bioanalytical Chemistry 396, 657-66. (IF-3.480; cited> 2).
11.     Rider SA, SJ Davies, AN Jha, R. Clough, JW Sweetman (2010) Bioavailability of co-supplemented organic and inorganic zinc and selenium sources in white fish-meal based rainbow trout (Oncorhynchus mykiss) diets. J. Animal Physiol. Animal Nutri.  94, 99-110. (IF-1.229; cited >0).
12.   Rider SA, SJ Davies, AN Jha, AS Fischer, J Kinght JW Sweetman (2009). Supra-nutritional dietary intake of selenite and selenium yeast in normal and stressed rainbow trout  (Onchorynchus mykiss): implications on selenium status and health responses. Aquaculture 295, 282-291(IF-1.925; cited > 3).
13.   Canty MN, TH Hutchinson, RJ Brown, MB Jones, AN Jha (2009) Linking genotoxic responses with cytotoxic and behavioural or physiological consequences: differential sensitivity of marine molluscs (Mytilus edulis) and echinoderms (Asterias rubens). Aquatic Toxicology 94, 68-76 (IF-3.124; cited >2).
14.  Petridis P, AN Jha, WJ Langston (2009) Measurements of the genotoxic potential of (xeno-) oestrogens in the bivalve mollusc Scrobicularia plana, using the Comet assay. Aquatic Toxicology 94, 8-15 (IF-3.124; cited> 3).
15.  Kumaravel TS , B Vilhar, SP Faux, AN Jha (2009) Comet Assay measurements: a perspective.Cell Biology & Toxicology 25, 53-64. (IF-1.746; cited>22).
16.     Dodd NJF, AN Jha (2009) Titaniumdioxide induced cell damage: A proposed role of the carbonyl radical. Mutation Research (Fundamental and Molecular Mechanisms of Mutagenesis), 660, 79-82 (IF- 3.556; cited >5).
17.  Al-Subiai SN, AN Jha, AJ Moody (2009) Contamination of bivalve haemolymph samples by adductor muscle components: implications for biomarker studies. Ecotoxicology 18, 334-342 (IF-3.507; cited >3).
18.  Vevers WF, AN Jha (2008) Genotoxic and cytotoxic potential of titanium dioxide (TiO2) nanoparticles on fish cells in vitro. Ecotoxicology 17, 410-420 (IF-3.507; cited > 40).
19. Jha AN (2008) Ecotoxicological applications and significance of the comet assay. Mutagenesis 23, 207-221 (IF-3.541; invited review article; cited> 56).
20.  Reeves JF, SJ Davies, NJF Dodd, AN Jha (2008) Hydroxyl radicals (·OH) are associated with titanium dioxide (TiO2) nanoparticle-induced cytotoxicity and oxidative DNA damage in fish cells. Mutation Research (Fundamental and Molecular Mechanisms of Mutagenesis), 640, 113-122 (IF-3.556; cited > 72).
21. Tran D, AJ Moody, AS Fisher, ME Foulkes, AN Jha (2007) Protective effects of selenium on mercury-induced DNA damage in mussel haemocytes, Aquatic Toxicology 84, 11-18. (IF: 3.124; cited >25).
22.  Atienzar FA, Jha AN (2006) The random amplified polymorphic DNA (RAPD) assay and related techniques applied to genotoxicity and carcinogenesis studies: a critical review, Mutation Research (Reviews) 613, 76-102. (IF: 7.097; cited > 46).
23.  Cheung VV, A Jha, R Owen, M Depledge, T Galloway (2006) Development of the in vivo chromosome aberration assay in oyster (Crassostrea gigas) embryo-larvae for genotoxicity assessment, Marine Environmental Research 62, S278-S282 (IF: 2.032; cited > 4).
24.  Jha AN, Y Dogra, A Turner, GE Millward (2006) Are low doses of tritium genotoxic to Mytilus edulis, Marine Environmental Research 62, S297-S300 (IF: 2.36; cited > 0).
25.  Cheung VV, MH Depledge, AN Jha (2006) An evaluation of the relative sensitivity of two marine bivalve mollusc species using the Comet assay, Marine Environmental Research 62, S301-S305. (IF: 2.032; cited >8).
26.  Kumaravel TS, AN Jha (2006) Reliable Comet assay measurements for detecting ionising radiation and chemical induced DNA damage, Mutation Research (Genetic Toxicology and Environmental Mutagenesis) 605, 7-16. (IF: 2.552; cited > 83).
27.  Hagger JA, FA Atienzar, AN Jha (2005) Genotoxic, cytotoxic, developmental and survival effects of tritiated water in the early life stages of the marine mollusc, Mytilus edulis. Aquatic Toxicology 74, 205-217. (IF: 3.124; cited > 18).
28.  Jha AN, Y Dogra, A Turner, GE Millward (2005) Impact of low doses of tritium on the marine mussel, Mytilus edulis: genotoxic effects and tissue-specific bioconcentration. Mutation Research (Genetic Toxicology & Environmental Mutagenesis) 586, 47-57. (IF: 2.552; cited > 24).
29.  Pascoe PL, AN Jha, DR Dixon (2004) Variation of karyotype composition and genome size in some gastropods from the northern hemisphere. Journal of Molluscan Studies 70, 389-398. (IF: 1.074; cited > 6).
30.  Jha AN (2004) Genotoxicological studies in aquatic organisms: an overview. (invited review article). Mutation Research (Fundamental and Molecular Mechanisms of Mutagenesis): 552, 1-17. (IF: 3.556; cited > 66).
31.  Atienzar FA, AN Jha (2004) The random amplified polymorphic DNA (RAPD) assay to determine DNA alterations, repair and transgenerational effects in B(a)P exposed Daphnia magna. Mutation Research (Fundamental and Molecular Mechanisms of Mutagenesis) 552, 125-140. (IF: 3.556; cited > 13).
32.  Raisuddin S, AN Jha (2004) Relative sensitivity of fish and mammalian cells to sodium arsenate and arsenite as determined by alkaline single cell gel electrophoresis and cytokinesis-block micronucleus assay. Environmental and Molecular Mutagenesis 44, 83-89. (IF: 2.868; cited > 26).
33.  Jackson D, M. Gilhen, A Jha (2003) International Scientific Workshop: Radioecology of Chernobyl Zone, Slavutych, Ukraine: 18-19 September 2002. The Science of the Total Environment 305, 263-265. (IF-2.905; cited > 1).
34.  Dixon DR, AM Pruski, LRJ Dixon, AN Jha (2002) Marine invertebrate eco-genotoxicology: a methodological overview. (Invited review article). Mutagenesis 17, 495-507. (IF: 3.541; cited > 62).
35.
Atienzar FA, P Venier, AN Jha, MH Depledge (2002) Evaluation of the random amplified polymorphic DNA (RAPD) for the detection of DNA damage and mutations. Mutation Research, 521, 151-163. (Genetic Toxicology & Environmental Mutagenesis) (IF: 2.552; cited > 40).
36.  Hagger JA, AF Fischer, SJ Hill, MH Depledge, AN Jha (2002): Genotoxic, cytotoxic and ontogenic effects of tri-n-butyltin (TBT) on the marine worm, Platynereis dumerilii (Polychaeta: Nereidae). Aquatic Toxicology 57, 243-255. (IF: 3.124; cited > 32).
37.  Atienzar, FA, AJ Evenden, AN Jha, MH Depledge (2002): The use of random amplified polymorphic DNA assay as a biomarker for the detection of diverse genetic alterations: possible implication of confounding factors. Biomarkers 7, 94-101. (IF: 1.728; cited > 14).
38.  Atienzar, FA, VV Cheung, AN Jha, MH Depledge (2001) Fitness parameters and DNA effects are sensitive indicators of copper induced toxicity in Daphnia magna. Toxicological Sciences 59, 241-250, 2001. (IF: 4.814; cited >28).
39.  Jha AN, JA Hagger, SJ Hill, MH Depledge (2000) Genotoxic, cytotoxic and developmental effects of tributyltin oxide(TBTO): an integrated approach to the evaluation of the relative sensitivities of two marine species. Marine Environmental Research 50, 565-573. (IF: 2.032; cited > 19 times).
40.  Atienzar, FA, B Cordi, ME Donkin, AJ Evenden, AN Jha, MH Depledge (2000) Comparison of ultraviolet-induced genotoxicity detected by random amplified polymorphic DNA with chlorophyll fluorescence and growth in a marine macroalgae, Palmaria palmata. Aquatic Toxicology 50, 1-12. (IF: 3.124; cited > 45).
41.  Jha AN, JA Hagger, SJ Hill (2000) Tributyltin induces cytogenetic damage in the early life stages of the marine mussel, Mytilus edulis. Environmental and Molecular Mutagenesis 35, 343-350. (IF: 2.868; cited > 28).
42.  Atienzar F, A Evenden, A Jha, D Savva, M Depledge (2000) Optimised RAPD analysis generates high quality genomic DNA profiles at high annealing temperature. BioTechniques 28, 52-54. (IF: 2.760; cited >23).
43. Jha AN, VV Cheung, ME Foulkes, SJ Hill, MH Depledge (2000) Detection of genotoxins in the marine environment: adoption and evaluation of an integrated approach using the embryo-larval stages of the marine mussel, Mytilus edulis. Mutation Research (Genetic Toxicology & Environmental Mutagenesis) 464, 213-228. (IF: 2.552; cited > 31).



Edited journals (Since 2000):

Jha AN: Special Issue of Mutation Research (Fundamental and Molecular Mechanisms of the Mutagenesis): Genotoxicological Studies in Aquatic Organisms Vol. 552, 1-2, August 2004, pp. 1-270.

Co-edited (Moore MN et al): Special Issue of Marine Environmental Research, Pollutant Response in Marine Organisms (PRIMO) 11 Symposium, Special Issue, Vol. 54, No. 3-5, 2002. Elsevier, pp 209-851.

Chapter in book:

Handy RD, AN Jha, MH Depledge (2002): Biomarker Approaches for Ecotoxicological Biomonitoring at Different Levels of Biological Organisation. Handbook of Environmental Monitoring (Chapter 9), McGraw-Hill, New York. ISBN 0-07-135176-0

 

Reports & invited lectures

Technical / Project Reports (since 2000):

1.   Handy RD, D Maycock, AN Jha (2009) An evaluation of the UK skills base for toxicologists and ecotoxicologists. Final report to DEFRA, UK. Contract No. RR102321.Available on line:  (http://randd.defra.gov.uk/Document.aspx?Document=CB0419_8185_FRP.pdf)
2. Hagger JA, AN Jha (2003) Evaluation of radionuclide induced genetic damage in marine invertebrates. PhD thesis as a final report to the Environment Agency, UK for National R & D Project P3-S1 and Devonport Royal Dockyard (DML), Plymouth.
3. Lowe David et al. (2000) Assessment of Impact of Ozone Depletion on Aquatic Ecosystems. Final Report to the Department of Environment, Transport and the Regions (DETR). Contract Reference EPG 1/1/49

 Scientific Sessions Chaired in International Conferences (since 2000):

International Symposium on Alternate Animal Models in Biological Research, Indian Institute of Toxicological Research, Lucknow, India, October 2010
40th Annual Conference of European Environmental Mutagen Society (EEMS), Oslo, Norway, September 2010 
NanoImpact Technical Workshop- Hazard Assessment of Nanomaterials in Biota- Dublin, R. of Ireland, September 2010
Genetic-Ecotoxicology session, 7th International Conference on Mutagenesis, Carcinogenesis and Teratogenesis, Organised by Brazilan Society of Environmental Mutagenesis, Carcinogenesis and Teratogenesis. Club Med, Brazil, October 2007  
Ecotoxicology Session, VII International Comet Assay Workshop, University of Ulster, Coleraine, Northern Ireland, UK, June 2007
III International Conference & VI Cuban Mutageneis, Teratogeneis & Carcinogeneis Workshop, Havana, Cuba, September 2006.
Chair, Session on Genotoxicity, 13th Pollutant Response in Marine Organisms (PRIMO 13) Symposium,Alessandria, Italy, June 2005
Session on Eco-genotoxicology, 33rd Annual Conference of the European Environmental Mutagen Society (EEMS), Aberdeen, Scotland, UK, August, 2003 
Session on Eco-genotoxicology, 25th Anniversary Conference of United Kingdom Environmental Mutagen Society (UKEMS), Plymouth, UK, June- July 2002
Session on Eco-genotoxicology, International Symposium on Environmental Genomics and Health Sciences; XXVII Annual Conference of the Environmental Mutagen Society of India (EMSI), Lucknow, India, March 2002
 Sessions on Genotoxicity, 11th Symposium on Pollutant Response in Marine Organisms (PRIMO), Plymouth, UK, July 2001

 

Invited Speaker in International Conferences (since 2000):

(** Fully /* Partially Sponsored)

*10th International Conference on Environmental Mutagens (ICEM), Florence, Italy, August 2009
**International meeting, Replacement of mammalian models: the role of in vitro techniques with fish and invertebrates, Society of Experimental Biology (SEB), Glasgow, UK June 2009
*2nd International Symposium on Genotoxicity in aquatic environment, Dessau, Germany, April 2008
*International Conference on Nanomaterial Toxicology, Indian Nanoscience Society, Lucknow, India, February 2008.
*7th International Conference on Mutagenesis, Carcinogenesis and Teratogenesis, Organised by Brazilan Society of Environmental Mutagenesis, Carcinogenesis and Teratogenesis. Club Med, Brazil, October 2007
*11th International Society of Invertebrate Reproduction and Development (ICRID), Smithsonain Tropical Research Institute (STRI), Panama City, Panama, August 2007
VII International Comet Assay Workshop, University of Ulster, Coleraine, Northern Ireland, UK, June 2007
* 30th Annual Conferene of Indian Society of Cell Biology (30th AICBC), University of Delhi, Delhi, India, February 2007 
III International Conference & VI Cuban Mutageneis, Teratogeneis & Carcinogeneis Workshop, Havana, Cuba, September 2006
*3rd Internationa Conference on Metals & radionuclides in the Environment, Vilnius, Lithuania, April 2006.
*35th Annual Conference of the European Environmental Mutagen Society (EEMS), Kos, Greece, July 2005 
* *20th Anniversary Low Level Radiation & Health Conference, Heriot-Watt University, Edinburgh, UK, July 2004 **International Symposium on Genotoxicity & Immunotoxicity: Unwelcome effects in aquatic systems, Koblenz, Germany, April 2004
** International Meeting on Protecting Biota from Ionising Radiation, Society of Radiological Protection (SRP), Royal College of Physicians, Edinburgh, UK, January 2004
*33rd Annual Conference of the European Environmental Mutagen Society (EEMS), Aberdeen, Scotland, UK, August 2003
*3rd International Symposium on the Protection of the Environment from ionising radiation, Darwin, Australia, July 2002 (could not participate)
**Asia-Pacific Conference on Marine Science and Technology, Kuala Lumpur, Malaysia, May 2002 *International Symposium on Environmental Genomics and Health Sciences; XXVII Annual Conference of the Environmental Mutagen Society of India (EMSI); Lucknow, India, March 2002
*International Symposium on Environmental Health Sciences in the 21st Century and 26th annual Conference of Environmental Mutagen Society of India, Jawaharlal Nehru University (JNU), New Delhi, India, March 2001 **Metals in Eastern and Central Europe: Health Effects, Sources of Contamination and Methods of Remediation, Prague, Czech Republic, November 2000 (organised by National Institute of Environmental Health and Sciences, USA)
30th Annual Meeting of the European Environmental Mutagen Society, Budapest, Hungary, August 2000

 

Conferences organised

Conferences Organised & Sessions Chaired (since 2000):

Organised, 33rd Annual Meeting of the European Environmental Mutagen Society (EEMS), Aberdeen, Scotland, UK, August 2003 (One of the member of the 10-membered Scientific/ Organising Committee)

Organised, 25th Anniversary Conference of the United Kingdom Environmental Mutagen Society (UKEMS) at University of Plymouth, Plymouth, UK, June- July 2002 (participated by approximately 200 delegates from all over the world)

Organised, 3 days Course (Course Director), Advanced Techniques in Aquatic Toxicology, Prior to 11th Symposium on Pollutant Response in Marine Organisms (PRIMO 11 symposium), at the University of Plymouth, Plymouth, UK, July 2001. (Attended by 35 participants from all over the world).

Organising Committee Member, 11th Symposium on Pollutant Response in Marine Organisms (PRIMO), Plymouth, UK, July 2001

 



Additional information

Awadhesh N. Jha

Email: a.jha@plymouth.ac.uk

Fax: +44 (0) 1752 584605

Postal Address:

School of Biomedical & Biological Sciences

Drake Circus

University of Plymouth

Plymouth, PL4 8AA, UK

 

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