Peninsula Clinical Trials Unit: CTIMPs

The following trials are fully managed:

ENRICH

Title: Randomised, Phase II open label study of Rituximab/Ibritinib vs Rituximab/Chemo in older patients with mantle cell lymphoma.

Chief Investigator: Professor Simon Rule, Plymouth Hospitals NHS Trust

CRUK       ISRCTN11038174

NoPac

Title: Novel use of TXA to reduce the need for nasal packing in epistaxis.

Chief Investigator: Dr Adam Reuben, Royal Devon and Exeter NHS Foundation Trust

ISRCTN34153772

PD STAT

Title: Simvastatin as a neuroprotective treatment for Parkinson’s disease – a double-blind, placebo controlled clinical learning study in patients of moderate severity.

Chief Investigator: Dr Camille Carroll, PUPSMD, Plymouth University

Study website       ISRCTN16108482

SUBLIME

Title: SUB-pectoral Local anaesthetic Infusion following MastEctomy.

Chief Investigator: Dr Roger Langford, Royal Cornwall Hospitals NHS Trust

CRUK       ISRCTN46621916       Protocol paper

The following studies are supported through the provision of randomisation and/or data services:

Facet Joint

Title: A pilot multicentre three arm randomised controlled feasibility study (for a definitive trial) of the clinical and cost-effectiveness of facet joint injections in patients with persistent non-specific low back pain of more than 6 months' duration.

Chief Investigator: Professor Richard Langford, Bath and The London NHS Trust

Study website       ISRCTN12191542