Project title: Targeting macrophages in schwannoma and meningioma tumours
Director of studies: Professor David Parkinson
2nd supervisor: Professor Oliver Hanemann
3rd supervisor: Professor Ji-liang Li
Applications are invited for a three-year PhD studentship. The studentship will begin on 1 January 2018.
The Plymouth University Peninsula Schools of Medicine and Dentistry (PUPSMD) are seeking to attract PhD candidates of outstanding ability to join their exciting and rapidly expanding programme of internationally-rated research. The Plymouth University Peninsula Schools of Medicine and Dentistry are committed to research excellence with a recent £25 million investment in staff and facilities. Medical research at PUPSMD was ranked first for outputs in REF2014.
are invited from suitably qualified graduates, 2:1 or above, and a relevant MSc or MRes qualification would be
desirable but not essential.
International students must also have an IELTS score of 7.0 or above (with no
less than 6.5 in any element).
position is to join a research group working on the biology of schwannoma and
meningioma tumours of the nervous system; these are relatively common tumour
types associated with the loss of the Merlin tumour suppressor. This project
involves the use of several transgenic mouse models to determine the genetic
signalling in these tumours as well as potential therapies involving the
modulation of the inflammatory environment within the tumour. This work will
involve the use of a wide range of in vivo and in vitro methodology including
molecular biology, protein analysis, confocal microscopy as well as the use of
transgenic in vivo systems. For further details on this and other ongoing
projects in the lab, please see Mindos et al (J. Cell Biol. 216: 495-510
(2017)); Schulz et al (Acta Neuropath. 132: 289-307 (2016) and Roberts et al
(Development 144: 3114-3125 (2017)).
For further information regarding the project, please contact Professor David Parkinson (email@example.com). However, applications must be made in accordance with the details shown below.