Dr Xinzhong Li
Profiles

Dr Xinzhong Li

Lecturer in Medical Statistics/Bioinformatics

Medical Statistics - Institute of Translational & Stratified Medicine (Plymouth University Peninsula Schools of Medicine and Den

Role

Lecturer in biostatistics and bioinformatics

Qualifications

PhD in Engineering from Xi'an Jiaotong University, China

Professional membership

Fellow of the Higher Education Academy

Roles on external bodies

1. Invited Peer Review for Research Grants/Fellowships

   •Medical Research Council (MRC)

2. Invited Peer Review for Professional Journals 
   •Scientific Reports (Nature)
   •Meta Gene (Elsevier) 
   •BMC Psychology
   •BMC Source Code for Biology and Medicine

3. Editorial/Scientific Board Members 
   •Scientific Reports (2017-) http://www.nature.com/srep/about/editorial-board#publichealth

Teaching interests

Bioinformatics Machine learning

Research interests

System biology and bioinformatics, biomarker discovery for brain disorder, disease diagnosis, machine learning, 


Grants & contracts

 • 2018 - 2021 MSCA-ITN-ETN AiPBAND project, Euro 3.7m, Coordinator at Plymouth University

 • 2017 - 2020 MSCA-ITN-ETN BBDiag project,  Euro 3.5m, co-investigator (Coordinator Prof Genhua Pan at Plymouth University)
 • 2016 - 2017 BRACE-Alzheimer’s Trust, £52,120 (PI)
 • 2016 - 2019 PhD studentship, Plymouth University. £42,171 (DoS)
 • 2014 - 2017 PhD studentship, Plymouth University. £41,286 (DoS) 

Key publications are highlighted

Journals
Articles
Zhang X, Peng J, Wang C, Feng Y, Feng Q, Li X, Chen W & He T 2017 'Improved Liver R2* Mapping by Averaging Decay Curves' Scientific Reports 7, (1) , DOI PEARL
Long J, Pan G, Ifeachor E, Belshaw R & Li X 2016 'Discovery of Novel Biomarkers for Alzheimer’s Disease from Blood' Disease Markers 2016, 1-9 , DOI PEARL
Li X, Long J, He T, Belshaw R & Scott J 2015 'Integrated genomic approaches identify major pathways and upstream regulators in late onset Alzheimer’s disease' Scientific Reports 5, (1) , DOI PEARL
Palles C, Chegwidden L, Li X, Findlay JM, Farnham G, Castro Giner F, Peppelenbosch MP, Kovac M, Adams CL & Prenen H 2015 'Polymorphisms Near TBX5 and GDF7 Are Associated With Increased Risk for Barrett’s Esophagus' Gastroenterology 148, (2) 367-378 , DOI PEARL
Mahajan A, Go MJ, Zhang W., Below JE & & et.al 2014 'Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility' Nature Genetics 46, (3) 234-244 , DOI
Chambers JC, Abbott J, Zhang W, Turro E & & et al 2014 'The South Asian genome' Plos One 9, (8)
Köttgen A, Albrecht E, Teumer A, Vitart V & et.al. 2013 'Genome-wide association analyses identify 18 new loci associated with serum urate concentrations' Nat Genet 45, (2) 145-154 Author Site , DOI
Feng Y, He T, Gatehouse PD, Li X, Harith Alam M, Pennell DJ, Chen W & Firmin DN 2013 'Improved MRI R2 * relaxometry of iron-loaded liver with noise correction' Magn Reson Med 70, (6) 1765-1774 Author Site , DOI
Paul DS, Albers CA, Rendon A & Voss K. et.al 2013 'Maps of open chromatin highlight cell type-restricted patterns of regulatory sequence variation at hematological trait loci' Genome Research 23, (7) 1130-1141 , DOI
Xinzhong Li, Andrew J. Buckton, Samuel L. Wilkinson, Shibu John, Roddy Walsh, Tomas Novotny, Iveta Valaskova, Manu Gupta, Laurence Game, Paul J.R. Barton & Stuart A. Cook & James S. Ware 2013 'Towards Clinical Molecular Diagnosis of Inherited Cardiac Conditions: A Comparison of Bench-Top Genome DNA Sequencers' PlosOne 8, (7) , DOI
Kelly MA, Rees SD, Hydrie MZ, Shera AS & et.al. 2012 'Circadian gene variants and susceptibility to type 2 diabetes: a pilot study' PLoS One 7, (4) Author Site , DOI
Okada Y, Sim X, Go MJ, Wu JY, Gu D & et.al. 2012 'Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations' Nat Genet. 2012 Jul 15;44(8):904-9. doi: 10.1038/ng.2352.
van der Harst P, Zhang W, Mateo Leach I, Rendon A & et.al 2012 'Seventy-five genetic loci influencing the human red blood cell' Nature 492, (7429) 369-375 Author Site , DOI
Chambers JC, Zhang W, Sehmi J, Li.X (joint first author) & et.al. 2011 'Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma' Nat Genet 43, (11) 1131-1138 Author Site , DOI
Wain LV, Verwoert GC, O'Reilly PF, Shi G & et.al. 2011 'Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure' Nat Genet 43, (10) 1005-1011 Author Site , DOI
Kooner JS, Saleheen D, Sim X, Sehmi J & et al. 2011 'Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci' Nat Genet 43, (10) 984-989 Author Site , DOI
Li.X (corresponding author), Thomason PA, Withers DJ & Scott J 2010 'Bio-informatics analysis of a gene co-expression module in adipose tissue containing the diet-responsive gene Nnat' BMC Syst Biol 4, Author Site , DOI PEARL
Antje Beyer, Peter Thomason, Xinzhong Li, James Scott & Jasmin Fisher 2010 'Mechanistic Insights into Metabolic Disturbance during Type-2 Diabetes and Obesity Using Qualitative Networks' T. Comp. Sys. Biology 12: 146-162
Books
He Y & Li X 2000 Neural Network Control Strategies and its Application. China Science Press Inc.
Chapters
Wang H, Li X & Bajic V 2004 'Neural-statistical model of TATA-box motif in eukaryotes' in Wong LW The Practical Bioinformatician World Scientific
Conference Papers
Li X, Adams C., Chegwidden L., Palles C., Tomlinson I., Farnham G. & Jankowski J. 2014 'Pathway Analysis of Genome Wide Association Study of Barrett's Oesophagus' Molecular Med TRI-CON 2014 San Francisco CA, U.S 09/02/2014 14/02/2014

Additional information

I moved to the CBBB at Plymouth University in February 2013 to become a lecturer, having previously spent almost 10 years as a bioinformatics research scientist at Imperial College London.