Professor Tom Hutchinson
Profiles

Professor Tom Hutchinson

Professor of Environment and Health Sciences

School of Geography, Earth and Environmental Sciences - Faculty of Science & Engineering (Faculties)

Role

Professor in Environment & Health Sciences
Leader Environment, Food & Biotechnology Research Group

Lead for International Student Recruitment in School of Biological Sciences
Member of Plymouth University's Sustainable Earth Institute

Qualifications

BSc. (Hons) Environmental Science (King's College, University of London)
Ph.D Marine Biology - Effects of Environmental Contaminants on Immune Functions of Marine Fish (University of Plymouth)
Elected Fellow of the Society of Biology
Honorary Professor, Institute for the Environment, Brunel University, UK
Honorary Professor, School of Biosciences, University of Exeter, UK

Professional membership

Elected Fellow of the Royal Society of Biology

Elected Fellow of the Linnean Society
Member of the British Toxicological Society (BTS)
Member of the Society of Environmental Toxicology and Chemistry (SETAC)

Roles on external bodies

Chair of the SETAC Global Advisory Group on Endocrine Disrupter Testing & Risk Assessment
Chair of the NC3Rs Working Group on Ecotoxicology
Member of the OECD Validation Management Group on Environmental Endocrine Disrupter Test Guidelines
Member of the OECD Invertebrate test Guideline Expert Group
Member of the UK Expert Committee on Pesticides

Science Leader for the UK-Japan Intergovernmental Research Cooperation on Environmental Endocrine Disrupters (2010-2015)

Teaching interests

BIOL111  Animal and Plant Physiology
BIOL121  Animal Physiology & Welfare

BIOL123  Field Biology 
BIOL119  Introduction to Biology
BIOL125PP  Scientific Method & Ethics in Biology
BIOL216  Animal Physiology and Health
BIOL311  Ecotoxicology
BIOL315  Biology Research Projects 
BIOL3425  Animals and Human Health
BIO504  Health and Prodution in Aquaculture
BIO5131  Postgraduate Research Skills and Methods

Research interests

Animal alternatives in ecotoxicology; hazard and risk assessment of endocrine disrupters; developmental and reproductive biology and toxicology of chemicals in aquatic organisms; molecular approaches to adverse outcome pathways of toxicity; environmental quality and sustainable aquaculture.

Research degrees awarded to supervised students

Information available from tom.hutchinson@plymouth.ac.uk

Grants & contracts

Details available from tom.hutchinson@plymouth.ac.uk

Research groups

  • Plymouth Sustainability and Surfing Research Group (PSSRG)

Hutchinson T.H. , Lyons B.P., Thain J., Law R.J., 2013. Evaluating legacy contaminants and emerging chemicals in marine environments using adverse outcome pathways and biological effects-directed analysis. Marine Pollution Bulletin 74: 517-525

Arnold K.E., Boxall A.B.A., Brown A.R., Cuthbert R.J., Gaw S., Hutchinson T.H., Jobling S., Madden J.C., Metcalfe C.D., Naidoo V., Shore R.F., Smits J.E., Taggart M.A., Thompson H.M. 2013 Assessing the exposure risk and impacts of pharmaceuticals in the environment on individuals and ecosystems. Biology Letters 9: 20130492, http://dx.doi.org/10.1098/rsbl.2013.0492

Jones H.S., Trollope H.T., Hutchinson T.H., Panter G.H., Chipman K.J., 2012. Metabolism of ibuprofen in zebrafish larvae. Xenobiotica 42: 1069-1075

Bartram A.E., Winter M.J., Huggett D.B., McCormack P., Constantine L.A., Hetheridge M.J., Hutchinson T.H., Kinter L.B., Ericson J.F., Sumpter J.P., Owen S.F., 2012. In vivo and in vitro liver and gill EROD activity in rainbow trout exposed to the beta-blocker propranolol. Environmental Toxicology & Chemistry 27: 573-582

Malham S.K., Hutchinson T.H., Longshaw M., 2012.  A review of the biology of European cockles (Cerastoderma spp). Journal of the Marine Biological Association of the UK 92(7): 1563-1577

David R.M., Jones, H.S., Panter G.H., Winter M.J., Hutchinson T.H., Chipman K.J., 2012.  Interference with xenobiotic metabolic activity by the commonly used vehicle solvents dimethylsulfoxide and methanol in zebrafish larvae but not Daphnia magna. Chemosphere 88: p.912-917

Ellis R.P., Parry H., Spicer J.I., Hutchinson T.H., Pipe, R.K., Widdicombe, S., 2011. Immunological function in marine invertebrates: Responses to environmental perturbation Fish & Shellfish Immunology 30: 1209-1222

Pope N.D., O'Hara S.C.M., Imamura M., Hutchinson T.H., Langston W.J., 2011. Influence of a collapsed coastal landfill on metal levels in sediments and biota - a portent for the future? Journal of Environmental Monitoring 13: 1961-1974

Celander M., Goldstone J., Denslow N., Iguchi T., Kille P., Meyerhoff R., Smith B., Hutchinson T.H., Wheeler J.R., 2011. Species extrapolation for the 21st century.  Environmental Toxicology and Chemistry 30: 52-63

Creton S., Douglas M., Wheeler J.R., Hutchinson T.H., 2010.  Challenging the requirement for chronic fish toxicity studies on formulated plant protection products.  Toxicology Letters 199: 111-114

Panter G.H., Hutchinson T.H., Hurd K.S., Bamforth J., Stanley R.D., Wheeler J.R., Tyler C.R., 2010.  Effects of a weak oestrogenic active chemical (4-tert-pentylphenol) on pair-breeding and F1 development in the fathead minnow. Aquatic Toxicology 97: 314-323

Craft J.A., Gilbert J.A., Temperton B., Dempsey K.E., Ashelford K., Tiwari B., Hutchinson T.H., Chipman J.K., 2010.  Pyrosequencing of Mytilus galloprovincialis cDNAs: tissue-specific expression patterns. PLoS One 5(1):e8875

Kádár E., Dashfield S., Hutchinson T.H., 2010. Developmental toxicity of benzotriazole in the protochordate Ciona intestinalis (Chordata, Ascidiae). Analytical Bioanalytical Chemistry 396: 641-647

Kádár E., Lowe D.M., Solé M., Fisher A.S., Jha A.N., Readman J.W., Hutchinson T.H. 2010. Uptake and biological responses to nano-Fe versus soluble FeCl3 in excised mussel gills.  Analytical Bioanalytical Chemistry 396: 657-666

Solé M., Shaw J.P., Frickers P.E., Readman J.W., Hutchinson T.H. 2010.  Effects on feeding rate and biomarker responses of marine mussels experimentally exposed to propranolol and acetaminophen.  Analytical Bioanalytical Chemistry 396: 649-656

Küster A., Alder A., Escher B., Duis K., Fenner K., Garric J., Hutchinson T.H., Lapen D., Duprey A., Römbke J., Snape J., Ternes T., Topp E., Wehrman A., Knacker T. 2010. Environmental risk assessment of human pharmaceuticals in the European Union - a case study with the b-blocker atenolol. Integrated Environmental Assessment and Management 6: 514-523

Schmitt H., Boucard T., Garric J., Jensen J., Parrott J., Péry A., Römbke J., Straub J.O., Hutchinson T.H., Sánchez-Argüello P., Wennmalm A., Duis K. 2010. Recommendations on the environmental risk assessment of pharmaceuticals: Effect characterizationIntegrated Environmental Assessment and Management 6: 588-602

Jones H.S., Panter G.H., Hutchinson T.H., Chipman J.K. 2010.  Oxidative and conjugative xenobiotic metabolism in zebrafish larvae in vivo. Zebrafish 7: 23-30

Canty M.N., Hutchinson T.H., Brown R.J., Jones M.B., Jha A.N. 2009. Linking genotoxic responses with cytotoxic and behavioural or physiological consequences: differential sensitivity of echinoderms (Asterias rubens) and marine molluscs (Mytilus edulis).  Aquatic Toxicology 94: 68–76

Jones H.S., Trollope H.T., Hutchinson T.H., Panter G.H., Chipman J.K. 2009. Assessment of an ibuprofen metabolism by zebrafish larvae, using liquid chromatography-mass spectrometry (LC-MS). Toxicology 262: 14-15

Boxall A.B., Hardy A., Beulke S., Boucard T., Burgin L., Falloon P.D., Haygarth P.M., Hutchinson T.H., Kovats R.S., Leonardi G., Levy L.S., Nichols G., Parsons S.A., Potts L., Stone D., Topp E., Turley D.B., Walsh K., Wellington E.M., Williams R.J. 2009.  Impacts of climate change on indirect human exposure to pathogens and chemicals from agriculture.  Environmental Health Perspectives 117: 508-514

Owen S.F., Huggett D.B., Hutchinson T.H., Hetheridge M.J., Kinter L.B., Ericson J.F., Sumpter J.P., 2009.  Uptake of propranolol, a cardiovascular pharmaceutical, from water into fish plasma and its effects on growth and organ biometry.  Aquatic Toxicology 93:  217-224

Giltrow E., Eccles P.D., Winter M.J., McCormack P.J., Rand-Weaver M., Hutchinson T.H., Sumpter J.P. 2009.  Chronic effects assessment and plasma concentrations of the beta-blocker propranolol in fathead minnows. Aquatic Toxicology 95:195-202

Hutchinson T.H., Bögi C., Winter M.J., Owens J.W. 2009.  Benefits of the Maximum Tolerated Dose (MTD) and Maximum Tolerated Concentration (MTC) concept in aquatic toxicology.  Aquatic Toxicology 91: 197–202

Hutchinson T.H., Beesley A., Frickers P.E., Readman J.W., Shaw J.P., Straub J.O. 2009.  Extending the environmental risk assessment for oseltamivir (Tamiflu®) under pandemic use conditions to the coastal marine compartment.  Environment International 35:  931-936

Jones H.S., Panter G.H., Hutchinson T.H., Chipman K.J. 2008. Cytochrome P450s and glucuronosyl transferase in zebrafish larvaeToxicology 253: 12-13

Hutchinson T.H., Björklund C., Jönsson R., Mahshid Y., Kenne K. 2008. Proteomic biomarkers for early stage phospholipidosis in human U937 cell lines. Toxicology in Vitro 22: 1198–1204

Richards F.M., Alderton W.K., Kimber G.M., Liu Z., Strang I., Redfern W.S., Valentin J.-P., Winter M.J., Hutchinson T.H. 2008. Validation of the use of zebrafish larvae in visual safety assessment. Journal of Pharmacological and Toxicological Methods 58: 50-58

Winter M.J., Redfern W.S., Hayfield A.J., Owen S.F., Valentin J.-P., Hutchinson T.H. 2008.  Validation of a larval zebrafish locomotor assay for assessing the seizure liability of early-stage development drugsJournal of Pharmacological and Toxicological Methods 57: 176-187

Caldwell D., Mastrocco F., Hutchinson T.H., Länge R., Heijerick D., Janssen C., Anderson P., Sumpter J. 2008.  Derivation of an aquatic Predicted No-Effect-Concentration for the synthetic hormone, 17a-ethinylestradiol.  Environmental Science & Technology  42: 7046-7054

Pounds N.A., Maclean S., Webley M., Pascoe D., Hutchinson T.H. 2008.  Acute and chronic effects of ibuprofen in the freshwater mollusc Planorbis carinatus (Gastropoda: Planorbidae).  Ecotoxicology & Environmental Safety 70(1): 47-52

Hooper H.L., Connon R., Callaghan A., Fryer G., Yarwood-Buchanan S., Biggs J., Maund S.J., Hutchinson T.H., Sibly R.M. 2008.  The ecological niche of Daphnia magna characterized using population growth rate.  Ecology 89(4): 1015–1022

Winter M.J., Lillicrap A.D., Caunter J.E., Schaffner C., Alder A.C., Ramil M., Ternes T.A., Giltrow E., Sumpter J.P., Hutchinson T.H.  2008.  Assessment of development and reproduction in fathead minnows exposed to atenolol. Aquatic Toxicology 86(3): 361-369

Heckmann L.H., Sibly R.M., Connon R., Hooper H.L., Hutchinson T.H., Maund S.J., Hill C.J., Bouetard A., Callaghan A. 2008.  Systems biology meets stress ecology: linking molecular and organismal stress responses in Daphnia magna.  Genome Biology 9:R40 (available from http://genomebiology.com/2008/9/2/R40)

Montforts M., Brandt I., Hutchinson T.H. 2007.  Summary of the DIA workshop on environmental assessment of human medicines: development and use of aquatic toxicity data.  Drug Information Journal 41: 203-209

Heckmann L.H., Callaghan A., Hooper H.L., Connon R., Hutchinson T.H., Maund S.J., Sibly R.M. 2007. Chronic toxicity of ibuprofen to Daphnia magna: effects on life history traits and population dynamics.  Toxicology Letters 172: 137-145

Winter M.J., Ellis L.C.J., Hutchinson T.H. 2007.  Formation of micronuclei in erythrocytes of the fathead minnow after acute treatment with mitomycin C or cyclophosphamide. Mutation Research 629: 89-99

Owen S., Giltrow E., Huggett D., Hutchinson T.H., Kinter L., Winter M.J., Sumpter J.P. 2007. Comparative physiology, pharmacology and toxicology of b-blockers: mammals versus fish.  Aquatic Toxicology 82: 145-162

Williams T.D., Caunter J.E., Lillicrap A.D., Hutchinson T.H., Gillings E.G., Duffell S. 2007.  Evaluation of the reproductive effects of tamoxifen citrate in partial and full life-cycle studies using fathead minnows.  Environmental Toxicology and Chemistry 26: 695-707

Hutchinson T.H. 2007.  Small is useful in endocrine disrupter assessment – four key recommendations for aquatic invertebrate research.  Ecotoxicology 16: 231-238

Thorpe K.L., Benstead R., Hutchinson T.H., Tyler C.R. 2007.  Associations between altered vitellogenin concentrations and adverse health effects in fathead minnow. Aquatic Toxicology 85: 176-183

Thorpe K.L., Benstead R., Hutchinson T.H., Tyler C.R. 2007. An optimised experimental test procedure for measuring chemical effects on reproduction in the fathead minnow, Pimephales promelas. Aquatic Toxicology 81: 90-98

Hutchinson T.H., Ankley G.T., Segner H., Tyler C.R. 2006.  Screening and testing for endocrine disruption in fish - biomarkers as “signposts not traffic lights” in risk assessment.  Environmental Health Perspectives 114 (Suppl 1): 106–114

Iguchi T., Irie F., Urushitani H., Tooi O., Kawashima Y., Roberts M., Norrgren L., Hutchinson T.H. 2006.   Availability of in vitro vitellogenin assay for screening of estrogenic and anti-estrogenic activities of environmental chemicals.  Environmental Sciences 13: 161-183

Crane H.M., Pickford D.B., Hutchinson T.H., Brown J.A. 2006.  The effects of methimazole on development of the fathead minnow from embryo to adult.  Toxicological Sciences 93: 278-285

Cunningham V.L., Buzby M., Hutchinson T.H., Mastrocco F., Parke N., Roden N. 2006.  Effects of human pharmaceuticals on aquatic life: next steps. Environmental Science and Technology  40:  3456–3462

Heckmann L.H., Connon R., Hutchinson T.H., Maund S.J., Sibly R.M., Callaghan A. 2006.  Expression of target and reference genes in Daphnia magna exposed to ibuprofen.  BMC Genomics 2006, 7:175 (article number #175)

Eidem J.K., Kleivdal H., Kroll K., Denslow N., van Aerle R., Tyler C.R., Panter G.H., Hutchinson T.H., Goksøyr A. 2006.  Development and validation of a direct homologous quantitative sandwich ELISA for fathead minnow vitellogenin. Aquatic Toxicology 78: 202–206

Noël H., Hopkin S., Hutchinson T.H., Williams T.D., Sibly R. 2006. Population growth rate and carrying capacity for springtails Folsomia candida exposed to ivermectin. Ecological Applications 16: 656–665

Noël H., Hopkin S., Hutchinson T.H., Williams T.D., Sibly R. 2006.  Towards a population ecology of stressed environments: the effects of zinc on the springtail Folsomia candida. Journal of Applied Ecology 43: 325–332

Hooper H.L., Connon R., Callaghan A., Maund S.J., Liess M., Duquesne S., Hutchinson T.H., Moggs J., Sibly R., 2006.  The use of image analysis to estimate population growth rate in Daphnia magnaJournal of Applied Ecology 43: 828-834

Hutchinson T.H., Shillabeer N., Winter M.J., Pickford D.B. 2006. Acute and chronic effects of carrier solvents in aquatic organisms: a critical review.  Aquatic Toxicology 76(1): 69-92

Jeram S., Riego Sintes J.M., Halder M., Baraibar Fentanes J., Sokull-Klüttgen B.,  Hutchinson T.H. 2005.  A strategy to reduce the use of fish in acute ecotoxicity testing of new chemical substances notified in the European Union.  Regulatory Toxicology and Pharmacology 42: 218-224

Brown R.J., Rundle S.D., Hutchinson T.H., Williams T.D., Jones M.B. 2005.  A microplate freshwater copepod bioassay for evaluating acute and chronic effects of chemicals.  Environmental Toxicology and Chemistry 24: 1528–1531

Crane H., Pickford D.B., Hutchinson T.H., Brown J.A. 2005.  Effects of ammonium perchlorate on thyroid function in developing fathead minnows. Environmental Health Perspectives 113: 396–401

Hooper H.L., Sibly R.M., Hutchinson T.H., Maund S.J. 2005. Joint effects of density and a growth inhibitor on the life history and population growth rate of the midge Chironomus ripariusEnvironmental Toxicology and Chemistry 24:1140-1145

Knacker T., Duis K., Ternes T., Fenner K., Escher B., Schmitt H., Römbke J., Garric J., Hutchinson T.H., Boxall A.B.A. 2005.  The EU-project ERAPharm: incentives for the further development of guidance documents? Environmental Science & Pollution Research 12: 62 – 65

Snape J.R., Maund S.J., Pickford D.B., Hutchinson T.H.  2004.  Ecotoxicogenomics: the challenge of integrating genomics into aquatic and terrestrial ecotoxicologyAquatic Toxicology 67: 143-154

Panter G.H., Hutchinson T.H., Hurd K.S., Sherren A., Stanley R.D., Tyler C.R. 2004. Successful detection of (anti-)androgenic and aromatase inhibitors in pre-spawning adult fathead minnows using easily measured endpoints of sexual development.  Aquatic Toxicology 70(1):11-21

Thomas-Jones E., Thorpe K.L., Harrison N., Thomas G., Morris C., Hutchinson T.H., Woodhead S., Tyler C.R. 2003.  Dynamics of estrogen biomarker responses in rainbow trout exposed to 17b-oestradiol and 17a-ethinylestradiol.  Environmental Toxicology and Chemistry 22: 3001-3008

Wallis N.T., Smith F.M., Panter G.H., Hutchinson T.H. 2003.  Laboratory fish gonadal sex differentiation: a comparison of fathead minnow, sheepshead minnow and zebrafish. Toxicology Sciences 72: 192-193

Hooper H.L., Sibly R.M., Hutchinson T.H., Maund S.J. 2003.  The influence of larval density, food availability and habitat longevity on the life history and population growth rate of the midge, Chironomus ripariusOikos 102: 515-524

Hooper H.L., Sibly R.M., Maund S.J., Hutchinson T.H. 2003.  The joint effects of larval density and 14C-cypermethrin on the life history and population growth rate of the midge, Chironomus ripariusJournal of Applied Ecology 40: 1049-1059

Thorpe K.L., Cummings R.I., Hutchinson T.H., Scholze M., Brighty G., Sumpter J.P., Tyler C.R. 2003.  Relative potencies and combination effects of steroidal oestrogens in fish.  Environmental Science & Technology 37: 1142-1149

Thorpe K.L., Benstead R., Hutchinson T.H., Cummings R.I., Tyler C.R. 2003. Reproductive effects of exposure to oestrone in the fathead minnow.  Fish Physiology & Biochemistry 28: 451-452

Hutchinson T.H., Barrett S., Busby M., Constable D., Hartmann A., Hayes E., Huggett D., Länge R., Lillicrap A.D., Straub J.O., Thompson R.S. 2003.  A strategy to reduce the numbers of fish used in acute ecotoxicity testing of pharmaceuticals.  Environmental Toxicology and Chemistry 22: 3031-3036

Pickford D.B., Hetheridge M.J., Caunter J.E., Tilghman Hall A., Hutchinson T.H. 2003.  Assessing chronic toxicity of bisphenol A to larvae of the African clawed frog (Xenopus laevis) in a flow-through exposure system.  Chemosphere 53: 223-235

Brown R.J., Rundle S.D., Hutchinson T.H., Williams T.D., Jones M.B. 2003.  Small-scale detritus-invertebrate interactions: influence of detrital biofilm composition on development and reproduction in a meiofaunal copepod.  Archives of Hydrobiology 157: 117-129

Brown A.R., Riddle A.M., Cunningham N.L., Kedwards T.J., Shillabeer N., Hutchinson T.H. 2003.  Predicting the effects of endocrine disrupting chemicals on fish populations.  Human & Ecological Risk Assessment 9: 761-788

Hutchinson T.H., Field M.D.R., Manning M.J. 2003.  Evaluation of non-specific immune functions in dab, Limanda limanda (L.), following short-term exposure to sediments contaminated with polyaromatic hydrocarbons and/or polychlorinated biphenyls.  Marine Environmental Research 55: 193-202

Brown R.J., Rundle S., Hutchinson T.H., Williams T.D., Jones M.B. 2003.  A copepod life-cycle test and growth model for interpreting the effects of lindane.  Aquatic Toxicology 63: 1–11

Hutchinson T.H., Pickford D.B. 2003.  Ecological risk assessment and testing for endocrine disruption in the aquatic environment.  Toxicology 181-182C: 383-387

van Aerle R., Pounds N., Hutchinson T.H., Maddix S., Tyler C.R. 2002.  Windows of sensitivity for the oestrogenic effects of ethynylestradiol in early life stages of the fathead minnow.  Ecotoxicology 11: 423-434

Pounds N.A., Hutchinson T.H., Williams T.D., Whiting P., Dinan L. 2002. Assessment of putative endocrine disrupters in an in vivo crustacean assay and an in vitro insect assay.  Marine Environmental Research 54: 709-713

Dinan L., Bourne P., Cary F., Whiting P., Harmatha J., Lafont R., Marion-Poll F., Dhadialla T.S., Hormann R.E., Hutchinson T.H. 2002. Structure-activity studies on natural and non-natural ligands for ecdysteroid receptors.  Journal of Insect Science 2.16: 5-6

Matthiessen P., Allen Y., Bamber S., Craft J., Hurst M., Hutchinson T.H., Feist S., Katsiadaki I., Kirby M., Robinson C., Scott A.P., Thain J.E.,  Thomas K. 2002.  The impact of oestrogenic and androgenic contamination on marine organisms in the UK – summary of the EDMAR programme.  Marine Environmental Research 54: 645-649

Hutchinson T.H. 2002.  Impacts of endocrine disrupters on fish development: opportunities for adapting OECD Test Guideline 210.  Environmental Sciences 9: 439-450

Hutchinson T.H. 2002. Reproductive and developmental effects of endocrine disrupters in invertebrates: in vitro and in vivo approaches.  Toxicology Letters 131: 75-81

Zerulla M., Länge R., Steger-Hartmann T., Panter G.H., Hutchinson T.H., Dietrich D.R. 2002.  Morphological sex reversal upon short-term exposure to endocrine modulators in juvenile fathead minnow. Toxicology Letters 131: 51-63

Panter G.H., Hutchinson T.H., Länge R., Lye C., Sumpter J.P., Zerulla M., Tyler C.R. 2002.  Utility of a juvenile fathead minnow screening assay for detecting (anti-)estrogenic substances.  Environmental Toxicology and Chemistry 21: 319-326

Halm S., Pounds N.A., Maddix S., Rand-Weaver M., Sumpter J.P., Hutchinson T.H., Tyler C.R. 2002.  Exposure to exogenous 17-oestradiol disrupts P450aromB mRNA expression in the brain and gonad of adult fathead minnows. Aquatic Toxicology 60(3-4):285-299

Tyler C.R., van Aerle R., Nilsen M.B., Blackwell R., Maddix S., Nilsen B.M., Berg K., Hutchinson T.H., Goksoyr A. 2002.  Development and validation of a monoclonal ELISA to quantify vitellogenin in the rainbow trout and its application for studies on environmental oestrogens. Environmental Toxicology and Chemistry 21: 47-54

Thorpe K.L., Hutchinson T.H., Hetheridge M.J.,  Scholze M., Sumpter J.P., Tyler C.R. 2001.  Assessing the interactive effects of binary mixtures of environmental oestrogens in rainbow trout using vitellogenin induction. Environmental Science & Technology 35: 2476-2481

Dinan L., Bourne P., Whiting P., Dhadialla T.S., Hutchinson T.H.  2001.  Screening of environmental contaminants for ecdysteroid agonist and antagonist activity using the Drosophila melanogaster BII cell in vitro assay. Environmental Toxicology and Chemistry 20: 2038-2046

Länge R., Hutchinson T.H., Croudace C.P., Siegmund F., Schweinfurth H., Hampe P., Panter G.H., Sumpter J.P. 2001.  Effects of the synthetic oestrogen 17a-ethinylestradiol over the life-cycle of the fathead minnow. Environmental Toxicology and Chemistry 20: 1216 – 1227

Hutchinson T.H., Brown R., Brugger K.E., Campbell P.M., Holt M., Länge R., McCahon P., Tattersfield L.J., van Egmond R. 2000. Ecological risk assessment of endocrine disruptors. Environmental Health Perspectives 108: 1007-1014

Thorpe K.L., Hetheridge M.J., Hutchinson T.H., Tyler C.R. 2000.  Development of an in vivo screening assay for estrogenic chemicals using juvenile rainbow trout (Oncorhynchus mykiss). Environmental Toxicology and Chemistry 19: 2812-2820

Hutchinson T.H., Matthiessen P. 1999.  Endocrine disruption and wildlife: identification and ecological relevance.  Science of the Total Environment 233: 1-3

Hutchinson T.H., Pounds N.A., Hampel M., Williams T.D. 1999.  Impact of natural and synthetic steroids on the survival, developmental and reproduction of marine copepods Tisbe battagliai.  Science of the Total Environment 233: 167-179

Hutchinson T.H., Field M.D.R., Manning M.J. 1999.  Evaluation of immune function in juvenile turbot (Scopthalmus maximus L.) exposed to sediments contaminated with polychlorinated biphenyls.  Fish and Shellfish Immunology 9: 457-472

Hutchinson T.H., Pounds N.A., Hampel M., Williams T.D. 1999.  Life-cycle studies with marine copepods (Tisbe battagliai) exposed to 20-hydroxyecdysone and diethylstilbestrol. Environmental Toxicology and Chemistry 18: 2914-2920

Tyler C.R., van Aerle R., Hutchinson T.H., Maddix S., Trip H. 1999.  An in vivo testing system for endocrine disruptors in fish early life-stages using induction of vitellogenin. Environmental Toxicology and Chemistry 18: 337-347

Hutchinson T.H., Jha A.N., Mackay J.M., Elliott B.M., Dixon D.R. 1998.  Evaluation of the genotoxicity of disinfected sewage effluent using the marine worm Platynereis dumerilii (Polychaeta: Nereidae).  Mutation Research 399: 97-108

Campbell P.M., Hutchinson T.H. 1998.  Wildlife and endocrine disrupters: requirements for hazard identification.  Environmental Toxicology and Chemistry 17: 127-135

Ankley G., Hutchinson T.H., … plus 28 workshop co-authors (1998) Overview of a workshop on screening methods for detecting potential (anti-) estrogenic/androgenic chemicals in wildlife.  Environmental Toxicology and Chemistry 17: 68 – 87

Solbé J.F., Mark U., Buyle B., Guhl W., Hutchinson T.H., Kloepper-Sams P.J., Länge R., Munk R., Scholz N., Bontinck W., Niessen H. 1998.  Analysis of the ECETOC Aquatic Toxicity (EAT) Database. I.  General Introduction.  Chemosphere 36: 99-113

Länge R., Hutchinson T.H., Scholz N., Solbé J.F. 1998.  Analysis of the ECETOC Aquatic Toxicity (EAT) Database. II. Comparison of acute to chronic ratios for various aquatic organisms and chemical substances.  Chemosphere 36: 115-127

Hutchinson T.H., Solbé J.F., Kloepper-Sams P.J. 1998.  Analysis of the ECETOC Aquatic Toxicity (EAT) Database. III. Comparative toxicity of chemical substances to different life stages of aquatic organisms.  Chemosphere 36: 129-142

Hutchinson T.H., Scholz N., Guhl W. 1998.  Analysis of the ECETOC Aquatic Toxicity (EAT) Database. IV. Comparative toxicity of chemical substances to freshwater versus saltwater organisms.  Chemosphere 36: 143-153

Palau-Casellas A., Hutchinson T.H. 1998.  Acute toxicity of chlorinated organic chemicals to the embryos and larvae of the marine worm Platynereis dumerilii (Polychaeta: Nereidae).  Environmental Toxicology and Water Quality 13: 149-155

Hutchinson T.H., Hutchings M.J., Moore K.W. 1997.  A review of the effects of bromate on aquatic organisms and toxicity of bromate to oyster embryos.  Ecotoxicology and Environmental Safety 38: 238 – 243

Carissan F.M., Hutchinson T.H., Beaumont A.R., Pipe R.K. 1997.  Investigation of the effects of sodium pentachlorophenol on the immune system of marine mussels. Developmental and Comparative Immunology 21: 125-126

Jha A.N., Hutchinson T.H., Mackay J.M., Elliott B.M., Dixon D.R. 1997.  Evaluation of the genotoxicity of municipal sewage effluent using the marine worm Platynereis dumerilii (Polychaeta: Nereidae).  Mutation Research 391: 179-188

Hutchinson T.H., Manning M.J. 1996.  Effects of cadmium on marine fish (Limanda limanda L.) kidney phagocyte chemiluminescence.  Marine Environmental Research 41: 327-342

Hutchinson T.H., Manning M.J. 1996.  Seasonal trends in serum total protein and lysozyme activity in marine fish (Limanda limanda L.) from Lyme Bay.  Fish and Shellfish Immunology 6: 473-482

Jha A.N., Hutchinson T.H., Mackay J.M., Elliott B.M., Dixon D.R. 1996.  Development of an in vivo marine genotoxicity test with Platynereis dumerilii (Polychaeta: Nereidae).  Mutation Research 359: 141-150

Hutchinson T.H., Jha A.N., Dixon D.R. 1995.  The polychaete Platynereis dumerilii: a new species for assessing the hazardous potential of chemicals in the marine environment.  Ecotoxicology and Environmental  Safety  31: 271-281

Jha A.N., Hutchinson T.H., Mackay J.M., Elliott B.M., Pascoe P., Dixon D.R. 1995.  The chromosomes of Platynereis dumerilii (Polychaeta: Nereidae).  Journal of the Marine Biological Association of the UK 75: 551-562

Jha A.N., Dominquez I.,  Balajee A.S., Hutchinson T.H., Dixon D.R., Natarajan A.T. 1995.  Localization of telomeric chromosome regions in two species of marine polychaete. Chromosome Research 3: 507-508

Field M.D.R., Hutchinson T.H., Manning M.J. 1995.  Development of adherence techniques for collecting kidney phagocytes from marine fish (Limanda limanda L.).  Fish and Shellfish Immunology 5: 505-517

Van Wijk D., Hutchinson T.H. 1995.  The ecotoxicity of chlorate to aquatic organisms: a critical review. Ecotoxicology and Environmental Safety 32: 244-253

Hutchinson T.H., Williams T.D. 1994.  Culturing of fathead minnow larvae for aquatic toxicity testing: an observational note.  Environmental Toxicology and Chemistry 13: 665‑669

Hutchinson T.H., Williams T.D., Eales G.J. 1994.  Toxicity of cadmium, hexavalent chromium and copper to marine fish larvae (Cyprinodon variegatus) and copepods (Tisbe battagliai).  Marine Environmental Research 38: 275‑290

Williams T.D., Hutchinson T.H., Roberts G.C., Coleman C.A. 1993.  The assessment of industrial effluent toxicity using aquatic microorganisms, invertebrates and fish.  Science of the Total Environment, supplement 1993 (part 2): 1129‑1141

Solbé J.F., Buyle B., Guhl W., Hutchinson T.H., Länge R., Mark U., Munk R., Scholz N. 1993.  Developing hazard identification for the aquatic environment.  Science of the Total Environment, supplement 1993 (part 1): 47-61

Simpson M.G., Hutchinson T.H. 1992.  Toxicological pathology of dab Limanda limanda along pollution gradients in the southern North Sea.  Marine Ecology Progress Series 91: 155-161

Hutchinson T.H., Williams T.D. 1989.  The use of sheepshead minnow (Cyprinodon variegatus) larvae and a benthic marine copepod (Tisbe battagliai) in short-term tests for estimating the chronic toxicity of industrial effluents.  Hydrobiologia 188: 567-572

Reports & invited lectures

Information available from tom.hutchinson@plymouth.ac.uk.

Other academic activities

Field Studies Council Biodiversity Fellow

Additional information

Canoe and kayak coach qualified with British Canoe Union
PADI Advanced Open Water Diver