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Profiles

Dr Thomas Mindos

Post-Doctoral Research Fellow

Plymouth University Peninsula Schools of Medicine and Dentistry

  • Room 2 floor research office, John Bull Building, Error retrieving address, Error retrieving address, Error retrieving address, Error retrieving address

Qualifications

BSc in Molecular Cellular Biology (University of Essex)

MSc in Molecular Pathology & Toxicology (University of Leicester)
PhD in Molecular Neuroscience (University of Bristol)

Research interests

Merlin acts as a tumour suppresor and hence is involved in a lot of cancers, primarily though in Schwannomas in type 2 neurofibromatosis. I am currently investigating the role of Merlin (NF2) in Schwann cell biology and peripheral nerve injury in mice. I research the co-operation of injury signals and loss of Merlin in the development of a proliferation-permissive environment that might lead to the formation of Schwannoma tumours.   

Other research

I have investigated the molecular mechanisms that lead to prostate cancer progression and the contribution of CCN1 (Cyr61) matricellular protein during this progression to the highly aggressive, metastatic and androgen-independent stage.

Research groups