- C406, Portland Square, Drake Circus, Plymouth, PL4 8AA
- +44 1752 586840
- louise.belfield@plymouth.ac.uk

Profiles
Dr Louise Belfield
Associate Professor of Biomedical and Oral Health Sciences (Education)
Peninsula Dental School (Faculty of Health)
Biography
Biography
I am a dental nurse and associate professor in biomedical and oral health sciences. My work focuses on scientific and educational elements required for excellence in research informed teaching. My major research interests lie in how oral bacteria can modulate the normal function of the immune system and drive conditions that lead to development of oral and systemic diseases, such as chronic periodontitis, oral cancer, and hypertension. My education research focuses on biomedical sciences, assessments and standard setting in inter-professional undergraduate curricula.
I first became involved with Dentistry when I began working as a dental nurse in 2001, spending 3 years in general practice, followed by 4 years working as a locum in dental specialties at South Devon Healthcare NHS Foundation Trust. I have always been fascinated by how bacteria in the mouth can exert effects in other sites in the body, and so both my undergraduate dissertation and my PhD focused on the role of one particular bacterium, Porphyromonas gingivalis, in modulating the host immune response. I continue to study the role of this particular bacterium in oral and systemic diseases as part of our Oral Microbiome Research Group at Peninsula Dental School.
Qualifications
2001 - NEBDN National Certificate in Dental Nursing
2008 - BSc (Hons) Human Biosciences2013 - PhD "Interactions between Porphyromonas gingivalis and macrophages in oral pathology"
2014 - Post graduate Certificate in Clinical Education
Professional membership
Associate Fellow: College of General Dentistry
International Association for Dental ResearchBritish Society for Oral and Dental Research
British Microcirculation Society
General Dental Council
Senior fellow of the Higher Education Academy
Roles on external bodies
Present:
Dental Clinical Fellow, Health Education England
Trustee / Director: National Examination board for Dental Nurses
Councillor: College of General Dentistry
Previous:
Councillor: British Society for Oral and Dental Research
Committee member: Association of Science Educators in Dentistry
Teaching
Teaching
Teaching interests
My subject specialties are:
- Biomedical Sciences including immunology, cell biology, cell signalling and microbiology.
- Dental nursing including infection control, decontamination and antimicrobial resistance.
- Inter-professional education for undergraduate dental professions.
My current roles within the Faculty of Medicine and Dentistry include:
- BSc Dental Therapy and Hygiene with Integrated Foundation Year
- Integrated Dental Science 1 Module lead, BSc Dental Therapy and Hygiene and Bachelor of Dental Surgery
- Lecturer: BSc Dental Therapy and Hygiene Bachelor of Dental Surgery, BSc (hons) Biomedical Sciences, BSc (hons) Nutrition, Bachelor of Medicine, Bachelor of Surgery.
- Curriculum development (Science): Developing the UKs first, fully integrated DTH/BDS programme.
- Widening Participation lead for Dentistry
Staff serving as external examiners
Cardiff University: BSc Dental Therapy and Dental Hygiene (years 2 and 3)
Research
Research
Research interests
Current research focuses on both scientific and educational elements required for excellence in research informed teaching. My major research interests lie in how oral bacteria can modulate the normal function of the immune system and drive conditions that lead to development of oral and systemic diseases, such as chronic periodontitis, oral cancer, and hypertension, as part of the Oral Microbiome Research Group: https://www.plymouth.ac.uk/research/biomedical-research-group/oral-microbiome-research-group
Current projects include:
- Modulation of osteoclast differentiation and activity by endotoxin tolerance
- Modelling single infections and dual biofilms of Candida albicans and Staphylococcus aureus on three-dimensional oral mucosal models
- Effects of mechanical strain on mesenchymal stem cell fate
- Regulation of tumour angiogenesis in response to periodontal bacteria
- Investigating the role of the oral microbiome in regulation of blood pressure
Publications
Publications
Key publications
Key publications are highlighted
Journals
Articles
(2022) 'Oral microbes and the formation of cerebral abscesses: a single-centre retrospective study' Journal of Dentistry , DOI Open access
(2021) 'Effects of chlorhexidine mouthwash on the oral microbiome' Journal of Dentistry 113, Publisher Site , DOI Open access
(2020) 'Current uses of chlorhexidine for management of oral disease: a narrative review' Journal of Dentistry 103, 103497-103497 Publisher Site , DOI Open access
(2020) 'Modulation of oral microbiota: A new frontier in exercise supplementation' PharmaNutrition 14, 100230-100230 , DOI Open access
(2020) 'Coronavirus Disease 2019 (COVID-19): Emerging and Future Challenges for Dental and Oral Medicine' Journal of Dental Research 99, (9) 1113-1113 , DOI Open access
(2020) 'Transfer of Basic Sciences Knowledge in a Problem‐Based Learning Curriculum' European Journal of Dental Education , DOI Open access
(2020) 'Effects of Chlorhexidine mouthwash on the oral microbiome' Scientific Reports 10, (1) 0-0 , DOI Open access
(2020) 'A core curriculum in the biological and biomedical sciences for dentistry' European Journal of Dental Education 24, (3) 433-441 , DOI
(2019) 'Comparative analysis of total salivary lipopolysaccharide chemical and biological properties with periodontal status' Archives of Oral Biology 110, 104633-104633 , DOI Open access
(2019) 'Effect of Constant versus Variable Small-Group Facilitators on Student Basic Science Knowledge in an Enquiry-Based Dental Curriculum' European Journal of Dental Education 0, (ja) , DOI Open access
(2019) 'A novel, integrated curriculum for dental hygiene-therapists and dentists' British Dental Journal 226, 67-67 Open access
(2018) 'Subgingival lipid A profile and endotoxin activity in periodontal health and disease' Clinical Oral Investigations , DOI Open access
(2018) 'The benefits of integrating dental and dental therapy and hygiene students in undergraduate curricula' European Journal of Dental Education , DOI Open access
(2017) 'Exposure to Porphyromonas gingivalis LPS during macrophage polarisation leads to diminished inflammatory cytokine production' Archives of Oral Biology 81, 41-47 , DOI Open access
(2015) 'Objective Structured Clinical Examination (OSCE) with Immediate Feedback in Early (Preclinical) Stages of the Dental Curriculum' Creative Education 06, (06) 585-593 , DOI Open access
(2012) 'Oral health and pathology: a macrophage account' Br J Oral Maxillofac Surg 50, (1) 2-7 , DOI Open access
Chapters
(2019) 'Immune System' in Ali K; Prabhakar E Essential Physiology for Dental Students John Wiley & Sons
(2016) 'Dental plaque and calculus' in Creanor S Essential Clinical Oral Biology John Wiley & Sons 136-143
Presentations and posters
'Exploring the relationships between knowledge and skills assessments in Dental Therapy and Hygiene students as a function of prior qualifications' Open access
Personal
Personal
Conferences organised
British Society of Oral and Dental Research National Conference, 6 - 8th September, 2017.
Oral Microbiology and Immunology Group Postgraduate residential scientific meeting, Gregynog, Wales, 2016.
Oral Microbiology and Immunology Group Postgraduate meeting, Newcastle University, 26th April 2012