Dr Kim Tieu
Profiles

Dr Kim Tieu

Associate Professor (Reader) in Clinical Neurobiology

Centre for Biomedical Research - Translational & Stratified Medicine (Peninsula Schools of Medicine and Dentistry)

Role

2013-present ║ Associate Professor (Reader) ║ Plymouth University Peninsula Schools of Medicine and Dentistry.

2013-present ║ Adjunct Faculty ║ University of Rochester (Rochester, New York). 

2015-present ║ Visiting Professor ║ Department of Neurology, Huashan Hospital, Fudan University (Shanghai, China).

Qualifications

2004-2012 ║ Assistant Professor ║ Depts. of Environmental Medicine and Neurology, University of Rochester (Rochester, New York).

2000-2004 ║ Post-doctoral fellow ║ Dept. of Neurology, Columbia University, New York.

1995-2000 ║ Ph.D ║ Neuroscience, University of Saskatchewan, Canada.

1993-2000 ║ Pharmacist ║ Saskatoon, Canada

1988-1993 ║ BSP ║ Pharmacy, University of Saskatchewan, Canada.

Professional membership

Society for Neuroscience
Society of Toxicology
Biochemical Society

Roles on external bodies

Invited Scientific Review
A) Journals : Annals of Neurology, Cell Biology and Toxicology, Cell Death and Disease, European Journal of Pharmacology, Experimental Neurology, Journal of Applied Toxicology, Journal of Neurochemistry, Journal of Neuroscience, Journal of Parkinson’s disease, Mitochondrion, Movement Disorders, Nanomedicine, Nature Communications, Nature Chemical Biology, Naunyn-Schmiedeberg Archives of Pharmacology, Neurobiology of Disease, Neurochemical Research, Neuropharmacology, Neuroscience, Neurotherapeutics, Neurotoxicology, Pharmacology and Therapeutics, PlosOne, Scientific Reports, Toxicological Sciences, Toxicology.

B) Grants: The National Institutes of Health (USA), Medical Research Council (UK), Parkinson’s UK, The French National Research Agency, The Research Grants Council (RGC) of Hong Kong.

Research interests

My research interest has always been to study mechanisms of neuronal dysfunction and degeneration as seen in Parkinson’s disease (PD), with the ultimate goal of developing effective therapies for this devastating neurological disorder.  The research projects in my lab focus on the following fundamental questions: 1) Is mitochondrial dysfunction pathogenic in PD? If so, can mitochondrial dynamics be targeted for PD treatment? 2) The role of genetic and environmental factors in the development and progression of PD? To address these questions, we perform rigorous biochemical, histological, functional and genetic analyses in experimental models of PD. When applicable, post-mortem human samples are also used.

Grants & contracts

Active
1) MRC ║ £511,230 (2014 - 2017) ║ PI: Kim Tieu
2) NIH ║ $740,000 (2014 - 2018) ║ PI: Kim Tieu

Completed
1) NIH ║ ~ $1,600,000 (2006 – 2012) ║ PI: Kim Tieu
2) NIH ║ ~ 422,000 (2009 – 2012) ║ PI: Kim Tieu
3) Environmental Protection Agency (EPA) ║ ~ $8,000,000 (2005 – 2010) ║ PI: Gunter Oberdoerster, Kim Tieu: 5% effort
4) NIH ║ $25,000 (2005 – 2006) ║ PI: Kim Tieu