Dr Jacob Day
Profiles

Dr Jacob Day

Honorary University Fellow

Peninsula Medical School (Faculty of Health)

Biography

Biography

NIHR Academic Clinical Fellow

Specialty Trainee Neurology

Qualifications

MSc Genomic Medicine, University of Exeter, 2019

Membership of the Royal College of Physicians (UK) 2016

BM BCh, University of Oxford, 2014

BA, University of Cambridge, 2011

Professional membership

Association of British Neurologists

Association of American Neurologists

Key publications

Bowman P, Day J, Torrens L, Shepherd MH, Knight BA, Ford TJ, Flanagan SE, Chakera A, Hattersley AT & Zeman A (2018) 'Cognitive, Neurological, and Behavioral Features in Adults With <i>KCNJ11</i> Neonatal Diabetes' Diabetes Care 42, (2) 215-224 , DOI
View all publications
Research

Research

Research interests

During my Academic Clinical Fellowship, I will learn machine learning methods as applied to healthcare. I will evaluate the use of these techniques in the diagnosis and prognosis of Parkinson's disease using routinely collected NHS data.

My previous research experience has included manipulation of large genomic datasets (by way of a genome-wide association study in the vividness of visual imagination) and the clinical evaluation of the neurological features of a rare form of monogenic diabetes.

Publications

Publications

Key publications

Bowman P, Day J, Torrens L, Shepherd MH, Knight BA, Ford TJ, Flanagan SE, Chakera A, Hattersley AT & Zeman A (2018) 'Cognitive, Neurological, and Behavioral Features in Adults With <i>KCNJ11</i> Neonatal Diabetes' Diabetes Care 42, (2) 215-224 , DOI

Key publications are highlighted

Journals
Articles
Day JO, Smith S, Noyce AJ, Alty J, Jeffery A, Chapman R & Carroll C (2022) 'Challenges of Incorporating Digital Health Technology Outcomes in a Clinical Trial: Experiences from PD STAT' Journal of Parkinson's Disease 1-5 , DOI Open access
Rawlins LE, Almousa H, Khan S, Collins SC, Milev MP, Leslie J, Saint-Dic D, Khan V, Hincapie AM & Day JO (2022) 'Biallelic variants in TRAPPC10 cause a microcephalic TRAPPopathy disorder in humans and mice' PLOS Genetics 18, (3) e1010114-e1010114 , DOI
Day JO & Mullin S (2021) 'The Genetics of Parkinson’s Disease and Implications for Clinical Practice' Genes 12, (7) 1006-1006 , DOI Open access
Abaleke E, Abbas M, Abbasi S, Abbott A, Abdelaziz A, Abdelbadiee S, Abdelfattah M, Abdul B, Abdul Rasheed A & Abdul-Kadir R (2021) 'Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial' The Lancet 397, (10274) 605-612 , DOI
Bowman P, Day J, Torrens L, Shepherd MH, Knight BA, Ford TJ, Flanagan SE, Chakera A, Hattersley AT & Zeman A (2018) 'Cognitive, Neurological, and Behavioral Features in Adults With <i>KCNJ11</i> Neonatal Diabetes' Diabetes Care 42, (2) 215-224 , DOI
Day JO & Bhatt P (2017) 'A man with paraesthesia, headache, and vertigo' BMJ j5165-j5165 , DOI
Day JO, Flanagan SE, Shepherd MH, Patrick AW, Abid N, Torrens L, Zeman AJ, Patel KA & Hattersley AT (2017) 'Hyperglycaemia-related complications at the time of diagnosis can cause permanent neurological disability in children with neonatal diabetes' Diabetic Medicine 34, (7) 1000-1004 , DOI Open access
Day JO, Day T & Day C (2017) 'A consequence of habitual nail bed trauma' BMJ j1200-j1200 , DOI
Day JO & Zeman AJ (2016) 'Limbic encephalitis driven by a pleural mesothelioma: A paraneoplastic complication' Middle East Journal of Cancer 7, (4) 221-223
Eagle DM, Noschang C, d'Angelo LSC, Noble CA, Day JO, Dongelmans ML, Theobald DE, Mar AC, Urcelay GP & Morein-Zamir S (2014) 'The dopamine D2/D3 receptor agonist quinpirole increases checking-like behaviour in an operant observing response task with uncertain reinforcement: A novel possible model of OCD' Behavioural Brain Research 264, 207-229 , DOI Open access
Conference Papers
Jacob D, Peter T & Nick G (2018) 'WED 201 A novel KIF1A mutation causing a neurodevelopmental disorder' BMJ A29.3-A29 , DOI
Day J, Torrens L, Bowman P, Shepherd M, Chakera A, Hattersley A & Zeman A (2016) 'KCNJ11 MUTATIONS CAUSE SEVERE NEUROPSYCHOLOGICAL DEFICITS' BMJ e1.195-e1 , DOI
Parsons B, Day J, Chan K, Taylor J & Crundwell M (2015) 'Use of percutaneous nephrostomies in the management of obstructive uropathy due to malignancy' British Association of Urological Surgeons , DOI