Dr Jacob Day
Profiles

Dr Jacob Day

School of Health Professions (Faculty of Health: Medicine, Dentistry and Human Sciences)

Role

NIHR Academic Clinical Fellow

Specialty Trainee Neurology

Qualifications

MSc Genomic Medicine (Distinction), University of Exeter, 2019

Membership of the Royal College of Physicians (UK) 2016

BM BCh (Distinction), University of Oxford, 2014

BA (1st class Honours) University of Cambridge, 2011

Professional membership

Association of British Neurologists

Association of American Neurologists

Research interests

During my Academic Clinical Fellowship, I will learn machine learning methods as applied to healthcare. I will evaluate the use of these techniques in the diagnosis and prognosis of Parkinson's disease using routinely collected NHS data.

My previous research experience has included manipulation of large genomic datasets (by way of a genome-wide association study in the vividness of visual imagination) and the clinical evaluation of the neurological features of a rare form of monogenic diabetes.

Key publications are highlighted

Journals

Bowman P*, Day J*, Torrens L, Shepherd MH, Knight BA, Ford TJ, Flanagan SE, Chakera A, Hattersley AT, Zeman A (2019). 'Cognitive, Neurological, and Behavioral Features in Adults With KCNJ11 Neonatal Diabetes.' Diabetes Care. 42(2):215-224. doi: 10.2337/dc18-1060 *Joint first authors.

Day JO, Flanagan SE, Shepherd MH, Patrick AW, Abid N, Torrens L, Zeman AJ, Patel KA, Hattersley AT (2017). 'Hyperglycaemia-related complications at the time of diagnosis can cause permanent neurological disability in children with neonatal diabetes'. Diabetic Medicine. 34(7):1000-1004. doi: 10.1111/dme.13328

Day JO, Bhatt P (2017). 'A man with paraesthesia, headache, and vertigo'. BMJ. 359:j5165. doi: 10.1136/bmj.j5165

Day JO, Day TH, Day HC (2017). 'A consequence of habitual nail bed trauma'. BMJ  356:j1200. doi: 10.1136/bmj.j1200

Day JO, Zeman AJ (2016) 'Limbic Encephalitis Driven by a Pleural Mesothelioma: A Paraneoplastic Complication'. Middle East Journal of Cancer 2016; 7 (4), 221-223

Eagle DM, Noschang C, d'Angelo LS, Noble CA, Day JO, Dongelmans ML, Theobald DE, Mar AC, Urcelay GP, Morein-Zamir S, Robbins TW (2014). 'The dopamine D2/D3 receptor agonist quinpirole increases checking-like behaviour in an operant observing response task with uncertain reinforcement: A novel possible model of OCD'. Behavioural Brain Research 1;264:207-29 doi: 10.1016/j.bbr.2013.12.040

Posters

Day JO, Turnpenny P, Gutowski NJ (2018). 'A novel KIF1A mutation causing a neurodevelopmental disorder'. Association of British Neurologists conference. doi.10.1136/jnnp-2018-ABN.101

Day JO, Torrens L, Bowman P, Shepherd M, Chakera A, Hattersley AT and Zeman AJ (2016). 'KCNJ11 mutations can result in severe cognitive and behavioural problems as well as neonatal diabetes: evaluation of seven adult patients'.  Diabetes UK conference. doi.10.1111/dme.47_13048

Parsons B, Day JO, Chan K, Taylor J, Crundwell M (2015). 'Use of percutaneous nephrostomies in the management of obstructive uropathy due to malignancy'. British Association fo Urological Surgeons conference. doi.10.1111/bju.13136