Dr Dyan Ankrett
Profiles

Dr Dyan Ankrett

Post-doctoral Research Fellow

School of Biomedical & Healthcare Sciences (Plymouth University Peninsula Schools of Medicine and Dentistry)

Role

Proteomic and degradomic analysis of human vascular tissue for the identification of cardiovascular disease biomarkers.

Qualifications

PhD; Cancer drug discovery and drug metabolism, De Montfort University.

Post-Doctoral Research:
Ultrasonic manipulation of biological cells in microfluidic devices, University of Southampton.
Cardiovascular disease biomarker discovery, Plymouth University. 

Research interests

Human tissue research, 3Rs philosophy (Reduction, Refinement and Replacement of animal experiments), natural product research, mass spectrometry, Lab-on-a-Chip technology.

Dario Carugo, Dyan Ankrett, Vincent O’Byrne, David D I Wright, Andrew L Lewis, Martyn Hill and Xunli Zhang.  The role of clinically-relevant parameters on the cohesiveness of sclerosing foams in a biomimetic vein model. Journal of Materials Science: Materials in Medicine, 26.11 (2015): 1-10. DOI: 10.1007/s10856-015-5587-z

Dario Carugo, Dyan N Ankrett, Xuefeng Zhao, Xunli Zhang, Martyn Hill, Vincent O’Byrne, James Hoad, Mehreen Arif, David D I Wright and Andrew L Lewis. Benefits of polidocanol endovenous microfoam (Varithena®) compared with physician-compounded foams. Phlebology OnlineFirst, published on June 1, 2015 as doi:10.1177/0268355515589063

Ankrett, Dyan N., Carugo, Dario, Lei, Junjun, Glynne-Jones, Peter, Townsend, Paul A., Zhang, Xunli and Hill, Martyn (2013) The effect of ultrasound-related stimuli on cell viability in microfluidic channels. Journal of  Nanobiotechnology, 11, (20), 1-5. (doi:10.1186/1477-3155-11-20).

Dario Carugo, Dyan Ankrett, Vincent O’Byrne, Sean Willis, David D I Wright, Andrew L Lewis, Martyn Hill and Xunli Zhang. A novel biomimetic analysis system for quantitative characterisation of sclerosing foams used for the treatment of varicose veins.  Journal of Materials Science: Materials in Medicine Accepted March 2013, (doi:10.1007/s10856-013-4913-6). (PMID:23512153).

Theodoros I. Roumeliotis, Maria Halabalaki, Xanthippi Alexi, Dyan Ankrett, Eugenia Giannopoulou,  Alexios-Leandros Skaltsounis,  Michael N. Alexis, Paul A. Townsend, and Spiros D. Garbis.  Pharmacoproteomic study of the natural product Ebenfuran III in DU-145 prostate cancer cells: The quantitative and temporal interrogation of chemically induced cell death at the protein level.  Journal of Proteome Research.  12,1591, 2012

Dario Carugo, Dyan N. Ankrett, Peter Glynne-Jones, Lorenzo Capretto, Rosemary J. Boltryk, Xunli Zhang, Paul A. Townsend and Martyn Hill.  Contrast agent-free sonoporation: the use of an ultrasonic standing wave microfluidic system for the delivery of pharmaceutical agents, Biomicrofluidics, 5, 044108(1)-044108(16), 2011.

Matthew D Rosser, Parvez I Haris, Dyan N Ankrett, Justin C Konje. The emerging role of epigenetics and miRNAs in endometriosis.  Expert Review of Obstetrics & Gynecology, July 2011, Vol. 6, No. 4, Pages 431-450

Conferences

Dyan N. Ankrett, Dario Carugo, Peter Glynne-Jones, Lorenzo Capretto, Rosemary J. Boltryk, Paul A. Townsend, Xunli Zhang and Martyn Hill.  A microstructured device for enabling accurate cell viability measurements during ultrasound-related stimuli.  Implementation of Microreactor Technology in Biotechnology (IMTB) International conference, Cavtat Croatia, May 2013. Conference paper accepted. Jan 2013

Dyan Ankrett, Peter Glynne-Jones and Martyn Hill.  Applications in acoustic manipulation of biological cells in micro-devices. Journal of the Acoustical Society of America 09/2012; 132(3):1953. (Invited speaker, 165th Meeting of the Acoustical Society of America, Kansas United States. 2012).

Roy Green, Rosemary J Boltryk, Dyan Ankrett, Peter Glynne-Jones, Paul A Townsend, Martyn Hill.. Controlling non-inertial cavitation microstreaming for applications in biomedical research. International Congress on Ultrasonics: Gdańsk 2011. AIP Conference Proceedings, Volume 1433, pp. 749-752 (2012).

Dyan N. Ankrett, Dario Carugo,  Peter Glynne-Jones, Lorenzo Capretto, Rosemary J. Boltryk, Roy Green, Martyn Hill  and Paul A. Townsend.  Ultrasonic micro-streaming and sonoporation of cardiac myoblasts - a mode of controlling cell survival? The 8th European Workshop on Cell Death, Monetier-les-Bains, France, June 2012– Poster presentation.

Peter Glynne-Jones, Puja Mishra, Dyan Ankrett, Rosemary J. Boltryk, Mathis Riehle and Martyn Hill. Practical design of devices for cell sorting and characterisation. International Congress on Ultrasonics: Gdańsk 2011. AIP Conference Proceedings.

Dario Carugo, Dyan N. Ankrett, Peter Glynne-Jones, Lorenzo Capretto, Rosemary J. Boltryk, Paul A. Townsend, Xunli Zhang and Martyn Hill.  Contrast agent-free cell sonoporation using a continuous-flow microfluidic device. Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2011), Seattle, Washington, United States, October 2011 – Poster presentation.

Other academic activities

Mass spectrometry, chromatography, cell and tissue engineering, drug metabolism,nutrition for disease prevention