Dr David Boyle

Dr David Boyle

Lecturer in Biology

School of Biological and Marine Sciences (Faculty of Science and Engineering)


I am a Lecturer in Marine Biology at the University of Plymouth



2018 - Present Lecturer in Marine Biology, University of Plymouth, UK

2018 Research Associate, Heriot-Watt University, UK

2015-2017 Postdoctoral Research Fellow, University of Plymouth, UK

2012-2014 Postdoctoral Fellow, University of Alberta, Canada

2009-2012 Postdoctoral Research Fellow, University of Plymouth, UK

2008-2009 Research Scientist, National Institute of Nutrition and Seafood Research, Norway



2015-2016 Postgraduate Certificate in Academic Practice, University of Plymouth, UK

2004-2008 PhD in Environmental Toxicology, King’s College London, UK

2002-2003 MSc in Aquatic Resource Management, King’s College London, UK

1999-2000 Research Assistant in Evolutionary Ecology, Imperial College London, UK

1997-2001 BSc (hons) in Applied Biology, University of Bath, UK

Research interests

My research focus is on the physiology and environmental toxicology of aquatic organisms.

Boyle, D., Goss, G.G., 2018. Effects of silver nanoparticles in early life-stage zebrafish are associated with particle dissolution and the toxicity of soluble silver. NanoImpact 12, 1-8.

Ede, J.D., Ortega, V.A., Boyle, D., Felix, L., Stafford, J.L., Martinez-Rubi, Y., Simard, B., Goss, G.G., 2018. Carbon nanotubes diminish IgE-mediated degranulation in the rat basophilic leukemia (RBL)-2H3 cell line. NanoImpact 9, 31-41.

Boyle, D. , Sutton, P.A., Handy, R.D., Henry, T.B., 2018. Intravenous injection of unfunctionalized carbon-based nanomaterials confirms the minimal toxicity observed in aqueousand dietary exposures in juvenile rainbow trout (Oncorhynchus mykiss). Environmental Pollution 232, 191-199 .

Khan, F.R., Boyle, D. , Chang, E., Bury, N.R., 2017. Do polyethylene microplastic beads alterthe intestinal uptake of Ag in rainbow trout (Oncorhynchus mykiss)?Analysis of the MP vector effect using in vitro gut sacs. Environmental Pollution 231, 200-206 .

Ong, K.J., Felix, L.C., Boyle, D. , Ede, J.D., Ma, G., Veinot, J.G.C., Goss., G.G., 2017. Humic acid ameliorates nanoparticle-induced developmental toxicity inzebrafish. Environmental Science: Nano 4, 127-137.

Boyle, D. , Blair, S.D., Chamot, D.,Goss, G.G., 2016. Characterization of developmental Na+ uptake inrainbow trout larvae supports a significant role for Nhe3b. Comparative Biochemistry & Physiology A 201, 30-36.

Ede, J.D., Ortega,V.A., Boyle, D., Beingessner, R.L., Hemraz, U.D., Fenniri, H., Stafford,J.L., Goss, G.G., 2016. The effects of rosette nanotubes with different functionalizations on channel catfish (Ictalurus punctatus) lymphocyte viability and receptor function. Environmental Science: Nano 3,578-592. 

Boran, H., Boyle, D. , Altinok, I., Patsiou,D., Henry, T.B., 2016. Aqueous Hg2+associates with TiO2 nanoparticles according to particle size,changes particle agglomeration, and becomes less bioavailable to zebrafish. Aquatic Toxicology 174, 242-246.

Al-Bairuty, G.A., Boyle, D., Henry, T.B., Handy, R.D., 2016. Sublethal effects of copper sulphate compared tocopper nanoparticles in rainbow trout (Oncorhynchusmykiss) at low pH: physiology and metal accumulation. Aquatic Toxicology 174, 188-198.

Ede, J.D., Ortega,V.A., Boyle, D., Beingessner, R.L., Hemraz, U.D., Fenniri, H., Stafford,J.L., Goss, G.G., 2015. Rosette nanotubes alter IgE-mediated degranulation inthe rat basophilic leukemia (RBL)-2H3 cell line. Toxicological Sciences 148, 108-120.

Ortega, V.A., Ede, J.D., Boyle, D., Stafford, J.L., Goss, G.G., 2015.Polymer-coated metal-oxide nanoparticles inhibit IgE receptor binding, cellular signalling and degranulation in a mast cell-lie cell line. Advanced Science 2, 1500104.

Dymowska, A.K., Boyle, D., Schultz A.G., Goss,G.G., 2015. The role of acid-sensing ion channels (ASICs) in epithelial Na+uptake in adult zebrafish (Danio rerio). Journal of Experimental Biology 218, 1244-1251.

Boyle, D. , Clifford, A.M., Orr, E.,Chamot, D., Goss, G.G., 2015a. Mechanisms of Cl- uptake in rainbowtrout: cloning and expression of slc26a6,a prospective Cl-/HCO3- exchanger. Comparative Biochemistry & Physiology A 180, 43-50.

Boyle, D., Boran, H., Atfield, A.J., Henry, T.B., 2015b. Use of an exposure chamber to maintain aqueous phasenanoparticle dispersions for improved toxicity testing in fish. Environmental Toxicology & Chemistry 34,583-588.

Cozzari, M., Elia, A.C., Pacini, N., Smith, B.D., Boyle, D., Rainbow, P.S., Khan, F.R., 2015. Bioaccumulation and oxidative stress responses measured in the estuarine ragworm (Nereis diversicolor) exposed to dissolved, nano- and bulk-sized silver. Environmental Pollution 198, 32-40.

Amlund,H., Lundebye, A.K., Boyle, D.,Ellingsen, S., 2015. Dietary selenomethionine influences the accumulation anddepuration of dietary methylmercury in zebrafish (Danio rerio). AquaticToxicology 158, 211-217.

Schultz, A.G., Boyle D., Chamot, D., Ong, K.J., Wilkinson, K.J., McGeer, J.C.,Sunahara, G., Goss, G.G., 2014. Aquatic toxicity of manufactured nanomaterials: challenges and recommendations for future toxicity testing. Environmental Chemistry 11, 207-226.

Sovová,T., Boyle, D., Sloman, K.A., Vanegas Pérez, C., Handy, R.D., 2014. Impaired behavioural response to alarm substance in rainbow trout exposed to copper nanoparticles. Aquatic Toxicology 152, 195-204 .

McNeil,P.L., Boyle, D., Henry, T.B., Handy,R.D., Sloman, K.A., 2014. Effects of metal nanoparticles on the lateral line system and behaviour in early lifestages of zebrafish (Danio rerio). Aquatic Toxicology 152, 318-323 .

Boyle, D. , Fox, J.E., Akerman, J.M., Sloman, K.A.,Henry, T.B., Handy, R.D., 2014. Minimal effects of waterborne exposure to single-walled carbon nanotubes on behaviour and physiology of juvenile rainbowtrout (Oncorhynchus mykiss). Aquatic Toxicology 146, 154-164 .

Boyle, D. , Al-Bairuty, G., Ramsden, C.S., Sloman, K.A.,Henry, T.B., Handy, R.D., 2013a. Subtle alterations in swimming speed distributions in rainbow trout exposed to titanium dioxide nanoparticles are associated with gill rather than brain injury. Aquatic Toxicology 126, 116-127.

Boyle, D. , Al-Bairuty, G.A., Henry, T.B., Handy, R.D., 2013b. Critical comparison of intravenous injection of TiO2 nanoparticles with waterborne and dietary exposures concludes minimal environmentally-relevant toxicity in juvenile rainbow trout Oncorhynchus mykiss. Environmental Pollution 182, 70-79.

Bury, N.R., Boyle, D., Cooper, C.A., 2012.Iron. In: Wood, C.M., Farrell, A.P., Brauner, C.J., eds. Homeostasis and toxicology of essential metals. London: AcademicPress, pp. 201-251.

Boyle, D. , Hogstrand, C., Bury, N.R., 2011. Physiological response to a metal-contaminated invertebrate diet inzebrafish: importance of metal speciation and regulation of metal transport pathways. Aquatic Toxicology 105, 21-28.

Lundebye, A-K., Lock, E-J., Boyle, D., Ruohonen, K., Berntssen, M.H., 2011. Tolerance of Atlantic salmon (Salmo salar) to dietborne endosulfan assessed by haematology, biochemistry, histology and growth. Aquaculture Nutrition 16, 549-558.

Handy, R.D., Al-Bairuty, G., Al-Jubory, A., Ramsden, C.S., Boyle, D., Shaw, B.S., Henry, T.B., 2011. Effects of manufactured nanomaterials on fishes: a target organ and body systems physiology approach. Journal of Fish Biology 79, 821-853 .

Boyle, D. , Amlund, H., Lundebye A-K., Hogstrand, C., Bury, N.R.,2010. Bioavailability of a natural lead-contaminated invertebrate diet to zebrafish. Environmental Toxicology &Chemistry 29, 708-714.

Boyle, D. , Brix, K.V., Amlund, H., Lundebye, A-K., Hogstrand, C., Bury, N.R., 2008. Natural arsenic contaminated diets perturb reproduction in fish. Environmental Science & Technology 42,5354-5360.

Tiën, N.S.H., Boyle, D., Kraaijeveld, A.R., Godfray, H.C.J., 2001. Competitive ability of parasitised Drosophila larvae. Evolutionary Ecology Research 3, 747-757.