Dr Alison Jeffery
Profiles

Dr Alison Jeffery

Trial Manager

Peninsula Medical School (Faculty of Health: Medicine, Dentistry and Human Sciences)

Role

Current: Trial Manager at Peninsula Clinical Trials Unit 

Past: Research Fellow, EarlyBird Diabetes Study 2000-2016

Qualifications

PhD in Child Health, Peninsula Medical School, 2010 

MSc Social Research, University of Plymouth, 2003

Registered Midwife 1985

Registered General Nurse 1982

Professional membership

UKCC Pin 79J3401E

Roles on external bodies

Interviewer Peninsula Medical School from 2007

Reviewer for Biomed Central Public Health, Diabetes Care, Diabetes, Diabetologia, International Journal Obesity, Child Health Care and Development, Pediatric Diabetes

Research interests

Trial methodology

Insulin resistance in childhood and adolescence

Recognition of childhood obesity

Grants & contracts

Novo Nordisk UK Nurses Research Fellowship 2006-2010

Novo Nordisk educational grant 2004-5

Johnson & Johnson Medical/Ethicon Nurse Education Trust Fund Study Grant 2003

Key publications are highlighted

Journals

  • 1.  Clinical and cost-effectiveness of teen online problem-solving for adolescents who have survived an acquired brain injury in the UK: protocol for a randomised, controlled feasibility study (TOPS-UK).
  • Limond J, Wade SL, Vickery PJ, Jeffery A, Warren FC, Hawton A, Smithson J, Ford T, Haworth S, Adlam AR.
  • BMJ Open. 2019 Aug 22;9(8):e029349. doi: 10.1136/bmjopen-2019-029349.  PMID: 31444185
  •  2. Insulin Resistance during normal child growth and development is associated with a distinct blood metabolic phenotype (Earlybird 72).
  • Hosking J, Pinkney J, Jeffery A, Cominetti O, Da Silva L, Collino S, Kussmann M, Hager J, Martin FP.
  • Pediatr Diabetes. 2019 Nov;20(7):832-841. doi: 10.1111/pedi.12884. Epub 2019 Jul 11.
  • PMID: 31254470

  • 3. Alison Jeffery. Cohort study: Parents who are aware when they are overweight themselves are more likely to recognise this in their children (commissioned article). Evid Based Nurs 2016 19:4;110
  • 4. . Jeffery A, Streeter AJ, Hosking J, Wilkin TJ, Nelson SM. Anti-Mullerian hormone in children: a ten-year prospective longitudinal study (EarlyBird 39). J Pediatr Endocrinol Metab 2015 May 20 pii: /j/jpem.ahead-of-print/jpem-2014-0517/jpem-2014-0517.xml. doi: 10.1515/jpem-2014-0517. [Epub ahead of print]
  • 5. Jeffery AN, Metcalf BS, Hosking J, Mostazir MB, Voss LD, Wilkin TJ. Awareness of body weight by mothers and their children: repeated measures in a single cohort (EarlyBird 64). Child Care Health Dev 2014 Jun 10: doi: 10.111/cch.12167 [Epub ahead of print]
  • 6. Alison N Jeffery, Michael E Hyland, Joanne Hosking, Terence J Wilkin. Mood and its association with metabolic health in adolescents: a longitudinal study, EarlyBird 65. Pediatr Diabetes. 2014 Feb 19. doi: 10.1111/pedi.12125. [Epub ahead of print]

  • Jeffery AN, Metcalf BS, Hosking J, Streeter AJ, Voss LD, Wilkin TJ. Age Before Stage: Insulin Resistance Rises Before the Onset of Puberty: A 9-year longitudinal study (EarlyBird 26). Diabetes Care 2012 Mar;35(3):536-41
  • Alison N Jeffery, Michael J Murphy, Brad S Metcalf, Joanne Hosking, Linda D Voss, Patrick English, Naveed Sattar, Terence J Wilkin. Adiponectin in childhood: Review article. International Journal Pediatric Obesity. 2008 3:130-140
  • Jeffery AN, Alba S, Murphy MJ, Voss LD, Metcalf BS, Hosking J, Gardner DS, Sattar N, Wilkin TJ. Behaviour of Insulin Resistance and its Metabolic Correlates in Pre-pubertal Children: a Longitudinal Study (EarlyBird 32). Diabetes Care Nov 2007 30;11:2962-64
  • Jeffery AN, Metcalf BS, Hosking J, Murphy MJ, Voss LD, Wilkin TJ. Little Evidence for Early Programming of Weight and Insulin Resistance for Contemporary Children: EarlyBird Diabetes Study Report 19  Pediatrics 2006;118(3):1118-1123
  • AN Jeffery, BS Metcalf, J Hosking, LD Voss, TJ Wilkin. Obesity-linked insulin resistance in children – an emerging problem. The EarlyBird Diabetes Study (31). European Journal Diabetes Nursing Spring 2006;3(1):41-45
  • Alison N Jeffery, Rosemary J Snaith, Linda D Voss. Insulin resistance in childhood: The EarlyBird Diabetes Study (12) Journal of Diabetes Nursing 2005;9(4):127-132
  • Alison N Jeffery, Linda D Voss, Rosemary J Snaith. Ethical dilemmas – feeding back results to members of a longitudinal cohort study. Journal Medical Ethics Mar 2005 31(3):153
  • Alison N Jeffery, Linda D Voss, Brad S Metcalf, Sandra Alba, Terence J Wilkin Parents’ awareness of overweight in themselves and their children: cross-sectional study within a cohort (EarlyBird 21). British Medical Journal 1 January 2005 330:23-4
  • Alison N Jeffery, Linda D Voss. Parents unable to weigh up childhood obesity. Leading article for Practical Diabetes International. Nov/Dec 2004 21;9:(commissioned article)
  • Alison N Jeffery, Linda D Voss, Brad S Metcalf, Joanne Kirkby, Jenny Perkins, Terence J Wilkin. The impact of pregnancy weight and glucose on the metabolic health of mother and child – The EarlyBird Study (14).  Midwifery 2004 20;3:281-289
  • Jeffery A. Insulin resistance (commissioned continuing professional development article) Nursing Standard 2003; 17(32):47-53, quiz 54-5
  • Jeffery AN, Wilkin TJ, Voss LD, Metcalf BS. The Pre- and Postnatal Causes of Insulin Resistance in Childhood. Nursing Standard 2002;16(35):33-37.
  •  
  • Lauria M, Persico M, Dordevic N, Cominetti O, Matone A, Hosking J, Jeffery A, Pinkney J, Da Silva L, Priami C, Monoliu I, Martin FP. Consensus Clustering of temporal profiles for the identification of metabolic markers of pre-diabetes in childhood (EarlyBird 73). Scientific Reports 2018 Jan;8(1):1393. doi: 10.1038/s41598-017-19059-2.
  • Jeffery SC, Hosking J, Jeffery AN, Murphy MJ, Voss LD, Wilkin TJ, Pinkney J. Insulin resistance is higher in pre-pubertal girls but switches to become higher in boys at age 16: a cohort study (Earlybird 57). Pediatric Diabetes 2017 Aug 29 doi 10.1111/pedi.12571 Epub ahead of print.
  • Mohammod Mostazir, Alison Jeffery, Linda Voss, Terence Wilkin. Generational Change in Fasting Glucose and Insulin among Children at Ages 5-16y Modelled on the EarlyBird study 2015 and UK growth standards (1990) (EarlyBird 69) Diabetes Research and Clinical Practice 2016. Accepted for publication 14.11.2016 DOI: http://dx.doi.org/10.1016/j.diabres.2016.11.014 -4- 2.
  •  
  • Mohammod Mostazir, Alison Jeffery, Joanne Hosking, Brad Metcalf, Linda Voss, and Terence Wilkin. Evidence for energy conservation during pubertal growth A 10-year longitudinal study (EarlyBird 71) Int J Obes (Lond). 2016 Sep 8. doi: 10.1038/ijo.2016.158.
  •  
  • Mostazir M, Jeffery A, Voss L, Wilkin T. Childhood Obesity: Evidence for Distinct Early and Late Environmental Determinants A 12-year longitudinal cohort study (EarlyBird 62) Int J Obes (Lond). 2016 Feb 40(2):380. Doi: 10.1038/ijo.2015.248
  •  
  • Metcalf BS, Hosking J, Henley WE, Jeffery AN, Mostazir M, Voss LD, Wilkin TJ. Physical activity attenuates the mid-adolescent peak in insulin resistance but by late adolescence the effect is lost: a longitudinal study with annual measures from 9-16 years (EarlyBird 66). Diabetologia 2015 Dec;58(12):2699-708. doi: 10.1007/s00125-015-3714-5. Epub 2015 Aug 12. Erratum in: Diabetologia. 2015 Dec;58(12):2900.
  •  
  • Metcalf BS, Hosking J, Jeffery AN, Henley WE, Wilkin TJ. Exploring the Adolescent Fall in Physical Activity: A 10-yr Cohort Study (EarlyBird 41). Med Sci Sports Exerc 2015 Oct:47(10):2084-92. Doi 10.1249/MSS. 0000000000000644.
  •  
  • Pinkney J, Streeter A, Hosking J, Mohammod M, Jeffery A, Wilkin T. Adiposity, chronic inflammation and the prepubertal decline of sex hormone binding globulin in children: evidence for associations with the timing of puberty (Earlybird 58). J Clin Endocrinol Metab 2014 Sep:99(9):3224-32.doi: 10.1210/jc.2013-3902 Epub 2014 Jun 13
  •  
  • Clarke-Harris R, Wilkin TJ, Hosking J, Pinkney J, Jeffery AN, Metcalf BS, Godfrey KM, Voss LD, Lillycrop KA, Burdge GC. Peroxisomal proliferator activated receptor-y-co-activator-1a promoter methylation in blood at 5-7 years predicts adiposity from 9-14 years (EarlyBird 50). Diabetes. 2014 Mar 12. [Epub ahead of print]
  •  
  • Hyland ME, Jeffery AN, Wilkin TJ. A biological, latent variable model of health (EarlyBird 68). Brain Behav Immun 2014 Mar 6 [Epub ahead of print]
  •  
  • Hosking J, Metcalf BS, Jeffery AN, Streeter AJ, Voss LD, Wilkin TJ. Evidence of early beta-cell deficiency among children who show impaired fasting glucose: 10-yr cohort study (EarlyBird 56).
  • Pediatr Diabetes. 2013 Nov;14(7):481-9. doi: 10.1111/pedi.12049. Epub 2013 May 31.
  •  
  • Mostazir M, Jeffery A, Voss L, Wilkin T. Gender-assortative waist circumference in mother-daughter and father-son pairs, and its implications. An 11-year longitudinal study in children (EarlyBird 59). Pediatr Obes. 2013 Apr 10. doi: 10.1111/j.2047-6310.2013.00157.x. [Epub ahead of print]
  •  
  • Streeter AJ, Hosking J, Metcalf BS, Jeffery AN, Voss LD, Wilkin TJ Body fat in children does not adversely influence bone development: a 7-year longitudinal study (EarlyBird 18). Pediatr Obes. 2013 Dec;8(6):418-27. doi: 10.1111/j.2047-6310.2012.00126.x. Epub 2013 Feb 28
  •  
  • Ajalo A, Hosking J, Metcalf BS, Jeffery AN, Voss LD, Wilkin TJ. The contribution of parental BMI to the metabolic health of their offspring: A longitudinal cohort study (EarlyBird 55). Pediatr Obes. 2012 Apr; 7(2):143-50
  •  
  • Hosking J, Metcalf BS, Jeffery AN, Voss LD, Wilkin TJ. Direction of causality between body fat and insulin resistance in children – a longitudinal study (EarlyBird 51). International Journal of Pediatric Obesity August 2011 (Epub ahead of print)
  •  
  • Fremeaux AE, Hosking J, Metcalf BS, Jeffery AN, Voss LD, Wilkin TJ. Consistency of children’s dietary choices: annual repeat measures from 5 to 13 years (EarlyBird 49). British Journal of Nutrition 2011 Sep;106(5):725-31
  •  
  • Ajala O, Fremeaux AE, Hosking J, Metcalf BS, Jeffery AN, Voss LD, Wilkin TJ. The relationship of height and body fat to gender-assortative weight gain in children. A longitudinal cohort study (EarlyBird 44). International Journal of Pediatric Obesity. 2011 Aug:6(3-4):223-8 Epub 2011 Jun 20
  •  
  • Hosking J, Metcalf BS, Jeffery AN, Voss LD, Wilkin TJ. Little impact of resting energy expenditure on childhood weight and body composition: a longitudinal study (EarlyBird 47). Nutr Res 2011 Jan 31(1):9-13
  •  
  • Metcalf BS , Hosking J, Frémeaux AE, Jeffery AN, Voss LD, Wilkin TJ . BMI was right all along: taller children really are fatter (implications of making childhood BMI independent of height) EarlyBird 48 Int J Obes advance online publication, February 8, 2011; doi:10.1038/ijo.2010.258
  •  
  • Metcalf BS, Hosking J, Jeffery AN, Voss LD, Henley W, Wilkin TJ. Fatness leads to inactivity but inactivity does not lead to fatness: a longitudinal study in children (EarlyBird 45). Arch Dis Child. 2010 Jun 23 (Epub ahead of print)
  •  
  • Voss LD, Hosking J, Metcalf BS, Jeffery AN, Fremeaux AE, Wilkin TJ. Metabolic risk in contemporary children is unrelated to socio-economic status: longitudinal study of a UK urban population (EarlyBird 42). Pediatric Diabetes. 2010 Epub
  •  
  • Hosking J, Henley W, Metcalf BS, Jeffery AN, Voss LD, Wilkin TJ. Changes in resting energy expenditure and their relationship to insulin resistance and weight gain: A longitudinal study in pre-pubertal children (EarlyBird 17) Clin Nutr. 2010 Feb 5. [Epub ahead of print]
  •  
  • Perez-Pastor EM, Metcalf BS, Hosking J, Jeffery AN, Voss LD, Wilkin TJ. Assortative weight gain in mother-daughter and father-son pairs: an emerging source of childhood obesity. Longitudinal study of trios (EarlyBird 43). Int J Obes 2009 33(7):727-35
  •  
  • Metcalf BS, Jeffery AN, Hosking J, Voss LD, Sattar N, Wilkin TJ. Objectively-measured physical activity and its association with adiponectin and other novel metabolic markers: a longitudinal study in children (EarlyBird 38). Diabetes Care 2009 Mar;32(3):468-73
  •  
  • Krishnan B, Jeffery A, Metcalf B, Voss L, Wilkin T, Flanagan D. Gender differences in the relationship between heart rate control and adiposity in young children: a cross-sectional study (EarlyBird 33). Pediatric Diabetes 2009 Apr;10(2):127-34
  •  
  • Gardner DS, Metcalf BS, Hosking J, Jeffery AN, Voss LD, Wilkin TJ. Contribution of Early Weight Gain to Childhood Development and Metabolic Health: A Longitudinal Study (EarlyBird 36). Pediatrics 2009 Jan;123(1):e67-73.
  •  
  • Metcalf BS, Voss LD, Hosking J, Jeffery AN, Wilkin TJ. Physical activity at the government-recommended level and obesity-related health outcomes: a longitudinal study (EarlyBird 37). Arch Dis Child 2008 93(9):772-7
  •  
  • Murphy M, Jeffery AN, Metcalf BS, Jeffery J, Hosking J, Voss LD, Sattar N, Williams R, Wilkin TJ. Distributions of adiponectin, leptin, and metabolic correlates of insulin resistance. A longitudinal study in British children: 1. Pre-puberty (EarlyBird 15) Clin Chem 2008 54(8):1298-306
  •  
  • Voss LD, Hosking J, Metcalf BS, Jeffery AN, Wilkin TJ. Children from low –income families have less access to sports facilities, but are no less physically active: cross-sectional study (EarlyBird 35). Child Care Health and Development May 2008
  •  
  • Michael J Murphy, Jo Hosking, Brad S Metcalf, Linda D Voss, Alison N Jeffery, Naveed Sattar, Roger M Williams, Jinny Jeffery, and Terence J Wilkin Distributions of adiponectin, leptin, and metabolic correlates of insulin resistance. A longitudinal study in British children: 1. Pre-puberty (EarlyBird 15) Clinical Chemistry 2008 (103499)
  •  
  • Gardner DS, Metcalf BS, Hosking J, Jeffery AN, Voss LD, Wilkin TJ. Trends, associations and predictions of insulin resistance in prepubertal children (EarlyBird 29). Pediatr Diabetes 2008 (epub ahead of print)
  •  
  • Jessica Roser, Alison Jeffery. Simple anthropometric measures to predict insulin resistance in children. Journal of Diabetes Nursing. 2007 11;10
  •  
  • Hosking J, Metcalf BS, Jeffery AN, Gardner D, Voss LD, Wilkin TJ. Resting energy expenditure, adiponectin and changes in body composition of young children (EarlyBird 34). Int J Ped Obesity 2007 Aug 29:1-6 (epub ahead of print)
  •  
  • Weedon MN, Clark VH, Qian Y, Ben-Shlomo Y, Timpson N, Ebrahim S, Lawlor DA, Pembrey ME, Ring S, Wilkin TJ, Voss LD, Jeffery AN, Metcalf B, Ferrucci L, Corsi AM, Murray A, Melzer D, Knight B, Shields B, Smith GD, Hattersley AT, Di Rienzo A, Frayling TM. A common haplotype of the glucokinase gene alters fasting glucose and birth weight: association in six studies and population-genetics analyses. Am J Hum Genet 2006 79;6:991-1001
  •  
  • Hosking J, Metcalf BS, Jeffery AN, Voss LD, Wilkin TJ. Validation of foot-to-foot bioelectrical impedance analysis with dual energy x-ray absorptiometry in the assessment of body composition in young children: the EarlyBird cohort. Br J Nutr 2006; 96(6):1163-8
  •  
  • Weedon MN, Clark VJ, Qian Y, Ben-Shlomo Y, Timpson N, Ebrahim S, Lawlor DA, Pembrey ME, Ring S, Wilkin TJ, Voss LD, Jeffery AN, Metcalf BS, Ferrucci L, Corsi AM, Murray A, Melzer D, Knight B, Shields B, Smith GD, Hattersley AT, Di Rienzo A, Frayling TM. A common haplotype of the glucokinase gene alters fasting glucose and birthweight association in six studies and population-genetics analyses. Am J Hum Genet 2006 79(6):991-1001
  •  
  • Murphy MJ, Metcalf BS, Jeffery AN, Voss LD, Wilkin TJ. Does lean rather than fat mass provide the link between birth weight, BMI and metabolic risk? EarlyBird 23. Pediatric Diabetes 2006 7(4):211-214
  •  
  • Wilkin TJ, Mallam KM, Metcalf BS, Jeffery AN, Voss LD. Variation in physical activity lies within the child, not his environment: evidence for an ‘activitystat’ in young children (EarlyBird 16). International Journal of Obesity 2006;30(7):1050-1055
  •  
  • Voss LD, Metcalf BS, Jeffery AN, Wilkin TJ. IOTF thresholds for overweight and obesity and their relation to metabolic risk in children (EarlyBird 20). International Journal of Obesity 2006 Apr;30(4):606-9
  •  
  • Metcalf B, Voss L, Jeffery A, Perkins J, Wilkin T Physical activity cost of the school run: impact on school children of being driven to school (EarlyBird 22) British Medical Journal 2004 329:832-3
  •  
  • Kirkby J, Voss LD, Metcalf BS, Jeffery AN, O’Riordan C, Perkins J, Wilkin TJ. Sex differences in resting energy expenditure and their relationship to insulin resistance in children (EarlyBird 13) Am J Clin Nutr 2004 Aug;80;2:430-435
  •  
  • Murphy MJ, Mallam KM, Voss LD, Metcalf BS, Jeffery AN, Kirkby J, Wilkin TJ. Girls at five are intrinsically more insulin resistant than boys: the programming hypotheses revisited – The EarlyBird Study (6) Pediatrics 2004 Jan;113(1):82-86.
  •  
  • Linda D Voss, Joanne Kirkby, Brad S Metcalf, Alison N Jeffery, Christina O’Riordan, Michael J Murphy, Terence J Wilkin. Preventable Factors in Childhood that Lead to Insulin Resistance, Diabetes Mellitus and the Metabolic Syndrome: The EarlyBird Diabetes Study (1) J Ped Endocrinol and Metab 2003, 16:1211-1224
  •  
  • Wilkin TJ, Metcalf BS, Voss LD, Murphy MJ, Metcalf BS, Howdle SM, Jeffery AN, Kirkby J. The relative contributions of birth weight, ‘catch-up’ weight and current weight to insulin resistance in contemporary five-year-olds: (EarlyBird 2). Diabetes 2002 Dec;51(12):3468-72.
  •  
  • Jeffery R, Jeffery A. Metachromatic Leukodystrophy: two sides of a coin. British Medical Journal (Personal view) 1993;307(6919):1631-2

Chapters

Alison N Jeffery The Seeds are Sown in Childhood: Insulin Resistance and the Global Epidemic of Type 2 diabetes. Chapter in Focus on Diabetes Mellitus Diabetes Research. 2005 Ashley M Ford (Ed), Nova Publishers, New York


Conference Papers

  • The challenges associated with delivering digital outcomes in a trial (PD STAT). International Clinical Trials Methodology Conference, Brighton, October 2019
  • Insulin resistance rises from mid-childhood, before the onset of puberty: Longitudinal data from the EarlyBird Study. Jeffery AN, Metcalf BS Hosking J Voss LD, Wilkin TJ. 4th Meeting of PreDiabetes and Metabolic Syndrome, Madrid, April 2011
  • Early weight gain programmes higher lean mass, not fat mass, at puberty, and lower metabolic risk.Jeffery AN, Murphy MJ, Metcalf BS, Hosking J, Frémeaux AE, Wilkin TJ. International Congress on Obesity (ICO) Stockholm, July 2010

  • Tracking insulin secretion and sensitivity in children who subsequently develop diabetes: a seven year study EASD Vienna Sept 29-Oct2 2009
  • Vector plotting of insulin secretion and insulin action over time may identify children at risk of developing diabetes: longitudinal data from the EarlyBird study. Diabetes UK Annual Professional Conference, Glasgow 11-13 March 2009
  • Jeffery AN, Metcalf BS, Hosking J, Voss LD, Wilkin TJ. New Insights into Control of Blood Glucose using the Disposition Model: a Longitudinal Analysis. International Society for Pediatric and Adolescent Diabetes (ISPAD), Durban, Aug. 2008
  • AN Jeffery, J Hosking, BS Metcalf, DS-L Gardner, MJ Murphy, LD Voss, TJ Wilkin. Visceral fat is not an independent predictor of insulin resistance in children. Diabetes UK Annual Professional Conference, Glasgow 14-16 March 2007
  • Alison Jeffery, Linda Voss, Joanne Hosking, Brad Metcalf, Terry Wilkin. Determinants of metabolic health in early childhood – The EarlyBird Diabetes Study. Federation European Nurses in Diabetes Conference. Copenhagen. Sep 12-13, 2006
  • Alison Jeffery The early origins of insulin resistance – longitudinal evidence from the EarlyBird cohort. The Rank Prize Funds Symposium on Environmental and Nutritional Influences on Infant Development and Behaviour. Grasmere October 3-6 2005
  • Jeffery AN, Alba S, Metcalf BS, Murphy MJ, Voss LD, Wilkin TJ. Metabolic re-modelling in prepubertal children – testing the lipid flux hypothesis. 14th European Congress on Obesity, Athens, 1-4 June 2005
  • Jeffery AN, Snaith RJ, Voss LD. Lessons to be learned from conducting a longitudinal study. Royal College of Nursing 2005 International Nursing Research Conference. Belfast 8-11 March 2005
  • Jeffery AN, Voss LD, Metcalf BS, Alba S, Wilkin TJ. Overweight families – unaware and unconcerned – The EarlyBird Diabetes Study. American Diabetes Association 64th Scientific Sessions. Orlando, Florida 4-8 June 2004
  • Jeffery AN, Voss LD, Metcalf BS, Alba S, Wilkin TJ. Overweight families – unaware and unconcerned – The EarlyBird Diabetes Study. 13th European Congress on Obesity, Prague. 26-29 May 2004
  • Jeffery AN, Voss LD, Metcalf BS, Wilkin TJ. Overweight families – unaware and unconcerned – The EarlyBird Diabetes Study. Diabetes UK Annual Professional Meeting, Birmingham, 17 March 2004
  • Jeffery AN, Voss LD, Metcalf BS, Kirkby J, Wilkin TJ. The impact of pregnancy weight and glucose on the metabolic health of mother and child – The EarlyBird Diabetes Study. British Society Paediatric Endocrinology and Diabetes. Annual Meeting, Plymouth 13-15 November 2002

Posters

1   The challenges of conducting an online paediatric study

Alison Jeffery, Jonny Wilks, Siobhan Mitchell, Laura Cocking, Janet Smithson, Anna Adlam International Clinical Trials Methodology Conference, Brighton, October 2019

2. The challenges of seeking online consent in a paediatric study

Alison Jeffery, Jane Vickery, Paul Williams, Laura Cocking, Anna Adlam

   

A Jeffery, J Sanders, W Ingrram, N Eastwood, B Wainman, J Zajicek. South West Impact of Multiple Sclerosis (SWIMS): a patient orientated longitudinal study. Plymouth Hospitals NHS Trust Research Event Plymouth Sept 2014

2    Alison N Jeffery, Michael E Hyland, Joanne Hosking, Terence J Wilkin. Mood and its association with metabolic health in children. Plymouth Hospitals NHS Trust Research Event, Plymouth 13-9-2013

1.   AN Jeffery, J Hosking, BS Metcalf, AJ Streeter, MBA Mostazir, LD Voss, TJ Wilkin. Insulin resistance rises before puberty, independently of body fat, and signals deteriorating metabolic health. A 10-year longitudinal study. 38th Meeting International Society Paediatric and Adolescent Diabetes, Istanbul, 10-13 October 2012

2.   Jeffery AN, Wilkin TJ, Insulin Resistance and Impaired Fasting Glucose during Puberty. 17th Annual Conference, Federation of European Nurses in Diabetes. Berlin 28-29 September 2012

3.   AN Jeffery, J Hosking, BS Metcalf, AJ Streeter, MBA Mostazir, LD Voss, TJ Wilkin. Insulin resistance rises before puberty, independently of body fat, and signals deteriorating metabolic health. A 10-year longitudinal study. American Diabetes Association Annual Meeting Philadelphia 8-12 June 2012

4.   AN Jeffery, BS Metcalf, J Hosking, AJ Streeter, MBA Mostazir, LD Voss, TJ Wilkin.

5.   Impact of Changes in Fat Distribution on the Metabolic Health of Children: a 5-year longitudinal study. European Congress on Obesity Lyons May 9-12 2012

6.   A.N. Jeffery, B.S. Metcalf, J. Hosking, A.J. Streeter, M.B.A. Mostazir, L.D. Voss, T.J. Wilkin. Insulin resistance rises from mid-childhood, before the onset of puberty: longitudinal data from The EarlyBird Diabetes Study. European Association for the Study of Diabetes (EASD) Lisbon Sept 2011

7.   Alison Jeffery, Linda Voss, Brad Metcalf, Terry Wilkin. Weight gain before and after the first birthday: effects on body composition and insulin resistance in adolescence. Riviera Research Day Torquay, 18 November 2010

8.   AN Jeffery, BS Metcalf, J Hosking, A E Fremeaux, LD Voss, TJ Wilkin. The Rise in Insulin Resistance Starts before Puberty: a Longitudinal Study. Diabetes UK Liverpool, 3-5 March 2010.

  1. Jeffery AN, Metcalf BS, Hosking J, Voss LD, Murphy MJ, Wilkin TJ. The differential effects of BMI and physical activity on insulin secretion and sensitivity in children – a longitudinal study. European Congress on Obesity (ECO). Amsterdam. 6-9 May, 2009.
  2. Tracking insulin secretion and sensitivity in children who subsequently develop diabetes: an eight year study. Alison N Jeffery, Brad S Metcalf, Joanne Hosking, Linda D Voss, Elena Perez-Pastor, Michael J Murphy*, Terence J Wilkin. 3rd International Meeting of Prediabetes and the Metabolic Syndrome and Diabetes Nice 1-4 April, 2009.

11. Jeffery AN, Metcalf BS, Hosking J, Voss LD, Wilkin TJ. Disposition modelling of blood glucose control in children: novel insights from a longitudinal study. European Association for the Study of Diabetes (EASD) Rome Sept 2008. Diabetologia 2008.

  1. Jeffery AN, Metcalf BS, Hosking J, Voss LD, Wilkin TJ. New insights into control of blood glucose using the disposition model: a longitudinal analysis (The EarlyBird Diabetes Study). European Congress on Obesity, Geneva, 2008 Shortlisted for best poster award
  2. Jeffery AN, Metcalf BS, Hosking J, Voss LD, Wilkin TJ Blood glucose control in children varies according to BMI: application of the disposition model. European Congress on Obesity, Geneva, 2008
  3. AN Jeffery, J Hosking, BS Metcalf, J Roser, LD Voss, TJ Wilkin Visceral and Subcutaneous Fat as Markers of Insulin Resistance in Children. Simple versus sophisticated measures of body fat in children and their relationship to insulin resistance International Society for Pediatric and Adolescent Diabetes (ISPAD) Berlin September 2007. Pediatric Diabetes
  4. AN Jeffery, BS Metcalf, J Hosking, J Roser, DS-L Gardner, LD Voss, TJ Wilkin. The effect of dietary choice on body size and insulin resistance in children: a longitudinal study. European Association for the Study of Diabetes (EASD) Amsterdam 2007. Diabetologia 2007
  5. AN Jeffery, BS Metcalf, J Hosking, J Roser, DS-L Gardner, LD Voss, TJ Wilkin. The effect of dietary choice on body size and insulin resistance in children: a longitudinal study. American Diabetes Association (ADA) Chicago, 2007. Diabetes 2007
  6. Alison N Jeffery, Michael J Murphy*, Linda D Voss, Brad S Metcalf, Joanne Hosking, Daphne S-L Gardner, Naveed Sattar**, Terry J Wilkin Evidence for Metabolic Re-modelling in Pre-pubertal Children – a Longitudinal Study Prediabetes Conference, Barcelona, 25-28 April 2007
  7. AN Jeffery, J Hosking, BS Metcalf, DS-L Gardner, LD Voss, TJ Wilkin Visceral and Subcutaneous Fat as Markers of Insulin Resistance in Children. European Congress on Obesity, Budapest April 22-25, 2007
  8. A Jeffery, J Hosking, B Metcalf, D Gardner, M Murphy, L Voss, N Sattar, T Wilkin Leptin Signaling may Dominate the Behaviour of Insulin in Young Children. International Diabetes Federation 19th World Diabetes Congress Cape Town 3-7 December, 2006.
  9. AN Jeffery, MJ Murphy, BS Metcalf, J Hosking, DS-L Gardner, LD Voss, N Sattar, TJ Wilkin. Adiponectin does not mediate obesity-related insulin resistance in young children: A longitudinal Study. European Association for the Study of Diabetes (EASD) Copenhagen, September 2006 Diabetologia Supp
  10. AN Jeffery, MJ Murphy, BS Metcalf, J Hosking, DS-L Gardner, LD Voss, N Sattar, TJ Wilkin. Adiponectin does not mediate obesity-related insulin resistance in young children: A longitudinal Study. International Society for Pediatric and Adolescent Diabetes (ISPAD) Cambridge September 2006. Pediatric Diabetes 2006 7;Suppl5:54
  11. AN Jeffery, MJ Murphy, BS Metcalf, J Hosking, DS-L Gardner, LD Voss, N Sattar, TJ Wilkin. Adiponectin does not mediate obesity-related insulin resistance in young children: A longitudinal Study. American Diabetes Association, Washington, June 2006 Diabetes Supp
  12. AN Jeffery, MJ Murphy, BS Metcalf, J Hosking, DS-L Gardner, LD Voss, N Sattar, TJ Wilkin. Adiponectin does not mediate obesity-related insulin resistance in young children: The EarlyBird Study. Diabetes UK Annual Professional Conference 2006 Diabetic Medicine 23;Supp2:P87
  13. AN Jeffery, S Alba, BS Metcalf, MJ Murphy, J Hosking, LD Voss, TJ Wilkin. Metabolic remodelling in pre-pubertal children - testing the lipid flux hypothesis European Association for the Study of Diabetes Athens 10-15 September 2005. Diabetologia 2005;48;suppl1:613
  14. Jeffery AN, Alba S, Metcalf BS, Murphy MJ, Hosking J, Voss LD, Wilkin TJ. Metabolic remodelling in pre-pubertal children - testing the lipid flux hypothesis. (selected for poster discussionInternational Society for Pediatric & Adolescent Diabetes (ISPAD), Krakow, 2005. Pediatric Diabetes 2005, Vol. 6 (Suppl 3), SP28, p 28.
  15. Jeffery AN, Alba S, Murphy M, Metcalf BS, Voss LD, Wilkin TJ. Metabolic re-modelling in pre-pubertal children- testing the lipid flux hypothesis: the EarlyBird Diabetes Study. American Diabetes Association, San Diego, 2005. Diabetes 2005 (Suppl).
  16. AN Jeffery, S Alba, BS Metcalf, MJ Murphy, LD Voss, TJ Wilkin. Metabolic re-modelling in prepubertal children. Diabetes UK Annual Professional Conference, Glasgow, April 20-22 2005. Diabetic Medicine Apr 2005;22;Supp2:P33
  17. Jeffery AN, Voss LD, Metcalf BS, Alba S, Wilkin TJ. Overweight families – unaware and unconcerned – The EarlyBird Diabetes Study. European Association for the Study of Diabetes. 40th EASD Meeting, Munich 5-9 September 2004 Diabetologia 2004 (suppl)
  18. Jeffery AN, Kirkby J, Metcalf BS, Perkins J, Voss LD, Wilkin TJ. The impact of pregnancy weight and glucose on the metabolic health of mother and child – The EarlyBird Study Diabetes UK Annual Professional Meeting, Glasgow Diabetic Medicine 2003;20(Suppl 2)P52
  19. AN Jeffery, J Kirkby, BS Metcalf, J Perkins, LD Voss, TJ Wilkin. The impact of pregnancy weight and glucose on the metabolic health of mother and child (selected for poster discussion) 18th Congress International Diabetes Federation, Paris 2003 A255;740
  20. Alison Jeffery, Linda Voss, Brad Metcalf, Terry Wilkin. Perceived body size in 7 year old children and their parents (The EarlyBird Diabetes Study) British Society for Paediatric Endocrinology and Diabetes, Annual Conference, Edinburgh, November 2003
  21. Jeffery AN, Voss LD, Metcalf BS, Mallam KM, Kirkby J, Murphy MJ, Wilkin TJ. Testing the fetal hypotheses for insulin resistance in contemporary children: The EarlyBird Study (Diabetes UK) Diabetic Medicine 2002, 19(Suppl. 2).
  22. Jeffery AN, Voss LD, Metcalf BS, Mallam KM, Kirkby J, Murphy MJ, Wilkin TJ. Predicting insulin resistance in contemporary children: genes, gestation or current weight? (Selected for poster discussion) American Diabetes Association, Diabetes 2002; 51(Suppl 2): A352, 1441-P
  23. Jeffery AN, Voss LD, Howdle S, Metcalf BS, Wilkin TJ. Weight at birth, gain in weight, current weight, and metabolic status in five-year-old children. the EarlyBird Study. (Diabetes UK) Diabetic Medicine 2001;18 (Suppl 2):120.

Reports & invited lectures

1. Keynote lecture to Federation of European Nurses in Diabetes, Annual Conference, Stockholm 2010

 2. Plenary lecture: Insulin Resistance during Puberty: The EarlyBird cohort as Teenagers. Plymouth Obesity Symposium, May 2012

3. Plenary lecture: Early Origins of Obesity and Diabetes: An update from The EarlyBird Study. Federation of European Nurses in Diabetes, Annual Conference, Barcelona, September 2013