Pain perception is a dynamic process that can be influenced by the activity of endogenous pain modulation systems in the brain, brainstem and spinal cord before we perceive an unpleasant stimulus as ‘pain’.
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Modelling chronic pain mechanisms in healthy volunteers
Using technology to harness endogenous pain relief
Exploring the link between sensory and affective components of chronic pain
Enhancing research through BRIC
The BRIC facility provides a collaborative and multidisciplinary research environment; with access to a range of psychophysical, neurophysiological, neuroimaging and non-invasive brain stimulation approaches, the Pain Neuroplasticity and Modulation Laboratory will investigate the sensitisation and modulation of central pain processing in both healthy volunteers and chronic pain patients.
The techniques used in the Pain Neuroplasticity and Modulation Laboratory include:
- quantitative sensory testing
- conditioned pain modulation
- electrocutaneous stimulation
- human pain and anxiety models
- temporal interference stimulation
- transcranial direct current stimulation
- virtual reality
- functional MRI
- diffusion tensor imaging.