Please contact us as early as possible so we can help you plan your research and include the costs of our support in your grant application. PenCTU does not provide funding for research.
If you need help with an existing study, please ensure you have sufficient funds to meet the costs of our support.
Peninsula Clinical Trials Unit
Faculty of Health
University of Plymouth
ITTC 1 Building
Plymouth Science Park
Welcome to the Peninsula Clinical Trials Unit (PenCTU) based within the Faculty of Health at the University of Plymouth.
We are a leading academic clinical trials unit with expertise in designing, developing, supporting and co-ordinating high quality, multi-centre clinical trials and other well-designed studies that will directly influence clinical and healthcare practice.
PenCTU is a fully registered clinical trials unit in the UK Clinical Research Collaboration (UKCRC) and currently receives National Institute for Health Research (NIHR) CTU support funding. This funding has been awarded to support the Unit in developing and supporting NIHR trials.
We work in partnership with clinicians, researchers, the NIHR Research Design Service South West, the Clinical Research Network and other partners from across the South West Peninsula and beyond, starting with the funding application, to deliver the full spectrum of clinical trial expertise to applicable standards and regulations.
PenCTU has considerable experience in drug trials, other non-drug interventional trials, trials of complex interventions, pilot trials and feasibility studies, across a broad range of clinical and health-related areas.
If you are interested in working with us, please approach us at the earliest opportunity.
Trial design and methodology
- Statistical expertise.
- Co-located with SW Research Design Service.
- Links with health economists.
- Links with qualitative researchers.
- Centralised operational team.
- Highly experienced trial managers.
- Project management from study set-up to close-out.
- Expertise in meeting regulatory and best practice standards.
Trial data management
- Centralised team of systems developers and data managers.
- Electronic and paper-based data capture.
- Bespoke web-based randomisation and trial management systems.
- Robust data processing and storage procedures.
- Suite of Standard
- Operating Procedures
- Established work instructions and templates
- Risk assessments
- Risk-based monitoring plans
We have experience in project-managing a portfolio of trials, with a focus on timely delivery and data quality. Following are some recent examples of our work, for further examples see our publications page.
REACH-HF - NIHR Journals
A facilitated home-based cardiac rehabilitation intervention for people with heart failure and their caregivers: a research programme including the REACH-HF RCT.
SAFE - BMJ Open
SAFE, a new therapeutic intervention for families of children with autism: a randomised controlled feasibility trial
LoDED - Heart
Limit of detection of troponin discharge strategy versus usual care: randomised controlled trial.
NoPAC - Annals of Emergency Medicine
The Use of Tranexamic Acid to Reduce the Need for Nasal Packing in Epistaxis (NoPAC): Randomized Controlled Trial.
We have experience in Clinical Trials of Investigational Medicinal Products (CTIMPs) as well as trials and other well designed studies not involving investigational medicinal products.
Video and audio
A selection of video and audio giving an introduction to Clinical Trials Units in general alongside some of our own work.
Study findings for trial participants
In this section you will find summarised results and findings of studies on our portfolio
Simvastatin as a neuroprotective treatment for Parkinson’s disease – a double-blind, placebo controlled clinical learning study in patients of moderate severity.
RCT of the LoDED (Limit of Detection of Troponin & ECG Discharge) strategy versus usual care in adult chest pain patients attending the A&E department.
Establishing a biobank and database as a national resource for characterising indolent and aggressive forms of mantle cell lymphoma
Teen Online Problem Solving for adolescents who have survived a brain injury in the UK (TOPS-UK): a feasibility study.
A randomised controlled trial exploring the effects of adding web-based coaching to an exercise referral scheme as a way to increase physical activity.
Postural modification to the standard Valsalva Manoeuvre for the emergency treatment of SVT (REVERT): a randomised controlled trial (RCT).
An open randomised trial of patient controlled analgesia (PCA) versus routine care in the emergency department.
In the news
- Why physical activity matters now more than ever 27 November 2020
- £2.5 million to study group treatment programme for people with severe obesity 25 September 2020
- Study to explore whether new therapy can help address problem drinking 4 August 2020
- Standing frame intervention improves life for people with MS, research shows 11 July 2019
- Mantle cell lymphoma patients living longer thanks to specialist clinic 1 July 2019