Martyn Gilpin

Martyn Gilpin

Job title: Lecturer in Molecular Genetics, School of Biomedical and Biological Sciences (Faculty of Science and Technology)
Address: ,
Telephone: +44 (0)1752 584627
Email: M.Gilpin@plymouth.ac.uk

Role

BSc (Hons) Microbial & Cellular Biology Programme Coordinator (2000-2006)

Member of the School of Biological Sciences Safety Committee - Biological Agents & GM Safety Advisor

Member of the University Safety Committee (1996-)
University Advisor on Genetic Modification (1996-)

Chairperson of the University Safety Sub-committee on Genetic Modification (1996 -2005)
Module Leader BIOL3310 Microbial Diseases & Biotechnology

Module Leader BIOL2001 Methods in Biological Sciences

Qualifications & background

Lecturer & Senior Lecturer in Molecular Genetics, University of Plymouth (1990 - present)

NAB Research Fellow, Plymouth Polytechnic (1988-1990)

Research Fellow, Hunterian Institute, Royal College of Surgeons of England, University of London. MRC funded (1984-87)

Ph.D in Microbial Genetics, University of Reading (1980 -1983)

B.Sc (Hons) in Microbiology, University of Surrey (1977 -1980)

Professional membership

Member of The UK Melioidosis Group.

Roles on external bodies
External Advisor to the Plymouth Marine Laboratory /Marine Biological Association Genetic Manipulation Committee. ( 2000-)

External Examiner, Ph.D : Tim Atkins, Department of Biochemistry, Imperial College of Science,Technology and Medicine, University of London. ‘Virulence Determinants of Burkholderia pseudomallei. 13/9/2000.

Teaching interests

Microbiology, microbial genetics, molecular techniques, gene cloning, microbial biotechnology, microbial pathogenicity.

Research interests
Molecular basis of the pathogenicity of bacterial pathogens. Molecular detection and typing systems for bacterial pathogens particularly with repect to the fish pathogen Renibacterium salmoninarum (Bacterial Kidney Disease), the human and animal pathogen Burkholderia pseudomallei (Mellioidosis) and the food poisoning agent Vibrio parahaemolyticus.

Research degrees awarded to supervised students

C Davies : Ph.D (2001). Molecular Characterisation of Burkholderia pseudomallei.

M.Mahfouz : Ph.D (2001). Molecular Biology of Burkholderia pseudomallei.

S. Alexander : Ph.D (2002). Molecular Differentiation of Renibacterium salmoninarum Isolates from the UK.

Michelle Stone : Ph.D (2004). The Use of Prebiotics to Improve Fish Health.
Edele Chambers : M.Phil (2005). Development of methods to assess the prevalence Renibacterium salmoninarum in selected river systems in England and Wales.

Grants & contracts

Gilpin, M L and Evenden, A J. DNA vaccines for aquaculture: development and testing of plasmid vectors for vaccinating against bacterial and viral pathogens. FAIR6-CT98-4003. European Union. A collaborative project with EU funding ( 960,000 ECU) and Industrial funding (563,741 ECU) making a Total funding of 1.523741 Million ECU. Amount of funding directly to Plymouth is 189,107 ECU. Three years, 01.01.1999 -01.01. 2002

Gilpin, M.L & Munn, C.B. Molecular characterisation of Burkholderia pseudomallei. [dstl]. 01.01.2002 - 01.01.2005. £50,000.

Gilpin, M.L & Munn, C.B. Molecular Characterisation of Vibrio parahaemolyticus . CEFAS , Weymouth, 01.09.02 - 31.08.06. £33,500

Gilpin, M.L, Evenden, A.J. & Munn, C.B. Partner institute within the thematic network Development Development of a European Resource on the Origins of Pathogens of Aquaculture (EUROPA) coordinated by University of Aberdeen, 01.01.03 -01.01.04, total funding for group Euros 26,000.

Publications

Grayson, T H, Cooper, L F, Atienzar F A, Knowles, M R and Gilpin, M L. (1999). Molecular Differentiation of Renibacterium salmoninarum isolates from Worldwide Locations. Applied and Environmental Microbiology, 65, 961-968.

Grayson, T H, Atienzar F A, Alexander, S.A, Cooper, L F, and Gilpin, M L. (2000). Molecular Diversity of Renibacterium salmoninarum isolates determined by randomly amplified polymorphic DNA. Applied and Environmental Microbiology, 66, 435-338.

Grayson, T H , Alexander, S.A, Cooper, L F, and Gilpin, M L. (2000). Renibacterium salmoninarum isolates from different sources possess two highly conserved copies of the rRNA operon Antonie van Leeuwenhoek: International Journal of General and Molecular Microbiology 78 (1):51-61.

Alexander, SM, Grayson, TH, Chambers, EM, Cooper, LF, Barker, GA, Gilpin, ML. 2001. Variation in the spacer regions separating tRNA genes in Renibacterium salmoninarum distinguishes recent clinical isolates from the same location. Journal of Clinical Microbiology, 39, 119-128.

Grayson, TH, Gilpin, ML, Evenden, AJ, and Munn, CB. 2001. Evidence for the immune recognition of two haemolysins of Renibacterium salmoninarum by fish displaying clinical symptoms of bacterial kidney disease (BKD). Fish and Shellfish Immunology, 11, 367-370

Grayson, T H, Cooper, L.F, Wrathmell, A.B, Roper, J, Evenden, A.J & Gilpin, M.L. 2002. Host responses to Renibacterium salmoninarum and specific components of the pathogen reveal the mechanisms of immune suppression and activation. Immunology, 106, 273-283.ISSN 0019-2805.

M. Snow, J. Barja., D. Colquhoun, C. Cunningham, M. Devold., C. Dopazo., K. Einer-Jensen., A. Evenden, P. Enzmann., M. L. Gilpin., A. Nylund., D. Stone & R. Thiery (2004). Developmen of a European Resource on the Origins of Pathogens of Aquaculture: The Europa Project. Bull.Eur. Ass. Fish Pathol.24(11) 54-57.

Magdy E. Mahfouz, T. Hilton Grayson , David A. B. Dance and Martyn L. Gilpin (2006). Characterization of the mrgRS locus of the opportunistic pathogen Burkholderia pseudomallei:temperature regulates the expression of a two-component signal transduction system. BMC Microbiology v.6 doi:10.1186/1471-2180-6-70 (published on-line). BioMed Central.

Reports & invited lectures

Gilpin, M L & Grayson, T.H. Development of PCR-based Detection Systems for Renibacterium salmoninarum for use in Diagnostic and Epizootiological Studies. MAFF Research Contract Final Project Report FC1103July 1999.