Role
To proactively lead the identification, development and commercialisation of the University’s intellectual property.
Professional membership
Member of the Institute of Knowledge Transfer (MInstKT)
Research interests
- Cryopreservation of the early life stages of marine invertebrates
- Cytogenetic markers of contaminants using Sister Chromatid Exchange
- Reproductive pathology in bivalves
- Embryo bioassay development
- Histological indices of nutritional and contaminant induced stress in the early life stages of fish
Grants & contracts
- DEFRA Cryogenic Bioassays (£198,000)
- DTI SMART Award (£65,000)
- DTI SMART Technology Review (£2000)
Contract Reports
Lowe D, Joint, I, McFadzen I, Donkin M, Gibbs S, Cheung V, Brown MT, Jha A, Cummins C (1999) Assessment of the impact of ozone depletion on aquatic ecosystems. Commissioned by Department of the Environment Transport and the Regions (DETR) 40 pp.
Publications
B.P. Lyons, F. Goodsir, J.E. Thain, J. Wedderburn and I.R.B. McFadzen (2006). Toxicity and phototoxicity of sea-surface microlayer samples to embryo-larval stages of the Pacific oyster Crassostrea gigas. 367-376 In: Hylland K; Lang T; Vethaak AD (Eds.). Biological effects of contaminants in marine pelagic ecosystems. Society of Environmental Toxicology and Chemistry.
Coombs, S.H., O, Giovanardi, N.C. Halliday, G. Franschescini, D.V.P. Conway, L. Manzueto, C.D. Barrett and I.R.B. McFadzen. (2003). Windmixing, food availability and mortality of anchovy larvae Engraulis encrasicolus, in the northern Adriatic Sea. Marine Ecology Progress Series. 248: 221-235.
B.P. Lyons, F. Goodsir, J.E. Thain, J. Wedderburn, I.R.B. McFadzen, (2002). Potential for UV-light to alter the toxicity of environmental seawater. ICES Copenhagen, CM2002/X:08, 13pp
B.P. Lyons, C.K. Pascoe and I.R.B. McFadzen, (2002). Phototoxicity of pyrene and benzo[a]pyrene to embryo-larval stages of the pacific oyster Crassostrea gigas. Marine Environmental Research, 54(3-5): 627-631.
McFadzen, I.R.B, S. Baynes, J. Hallam, A. Beesley, D. Lowe. (2000). Hisopathology of the skin of UV-B irradiated sole (Solea solea) and turbot (Scophthalmus maximus). Marine Envrionmental Research 50: 273-277.
Wedderburn, J., I. McFadzen, R.C. Sanger, A. Beesley, C. Heath, M. Hornsby, D. Lowe. (2000), The field application of cellular and physiological biomarkers, in the mussel Mytilus edulis, in conjunction with early life stage bioassays and adult histopathology. Marine Pollution Bulletin, 40: (3), 257-267.
McFadzen, I.R. B, N. Eufemia, C. Heath, D. Epel, M. Moore, D. Lowe (2000). Multidrug resistance in the embryos and larvae of the mussel Mytilus edulis. Marine Envrionmental Research 50: 319-323.
McFadzen, I. Determination of water wuality in the Venice Lagoon utilising the early life stages of a fish (Sparus aurata) and an echinoderm (Paracentrotus lividus). (2000) In: Man and the Biosphere Series Vol 25. The Venice Lagoon Ecosystem: Inputs and interations between land and Sea. Eds. P. Lasserre & A. Marzollo. 339-356.
Wedderburn, J. I. McFadzen, R.C. Sanger, A. Beesley, C. Heath, M. Hornsby, D. Lowe. (2000). Biomarkers: the application of a suite of techniques to determine environmental quality. Marine Environmental Research. 50: 431.
McFadzen I.R.B. & Franceschini G., (1997) - Nutritional conditions of larvae of anchovy (E. encrasicholus) in the outflow of the River Po. Acta Adriatica, 38 (1): 49-64
McFadzen, I.R.B, S.H. Coombs, N.C. Halliday. (1997). Histological indices of the nutritional condition of sardine Sardina pilchardus larvae off the north coast of Spain. Journal of Experimental Marine Biology and Ecology. 212: 239-258.
Franceschini G., McFadzen I. R. B., Giovanardi O., Conway D., Coombs S. & Halliday N., (1996) - Dati preliminari sulle condizioni nutrizionali delle larve di acciuga (E. encrasicholus L.) nelle acque prospicienti il delta del Po (Campagna A.L.I.C.E. '95). Biol.Mar. Medit., 4 (1): 298-300.
Giovanardi O., Coombs S., Franceschini G., Conway D., McFadzen I.R.B. & Halliday N., (1996) - Distribuzione verticale ed orizzontale di uova e larve di acciuga (E. encrasicholus L.), del microzooplancton e del particellato nelle acque prospicienti il delta del Po (Campagna A.L.I.C.E.'95). Biol.Mar. Medit., 301-302.
McFadzen, I., Cook, K., 1996. The distribution of blue whiting larvae (Micromesistius poutassou) to the west of the British Isles. ICES C.M. 1996/S:19.
McFadzen, I.R.B. Cryopreservation of the sperm of the Pacific oyster Crassostrea gigas. (1995). In: Methods in Molecular Biology Vol. 38. Cryopreservation and Freeze-drying Eds: J.G. Day and M.R. McLellan.
McFadzen, I.R.B., D.M. Lowe, S.H. Coombs (1994). Histological changes in starved turbot larvae (Scophthalmus maximus) quantified by digital image analysis. Journal of Fish Biology. Vol. 44 Issue 2 Page 255
McFadzen, I.R.B., Cleary, J.J. (1994). Toxicity and chemistry of the sea-surface microlayer in the North Sea using a cryopreserved larval bioassay. Marine Ecology Progress Series 103: 103-109.
Conway, D.V.P, I.R.B. McFadzen, P.R.G. Tranter. (1994). Digestion of copepod eggs by larval turbot and egg viability following gut passage. Marine Ecology Progress Series. 106: 303-309.
McFadzen, I.R.B. Growth and survival of cryopreserved oyster and clam larvae along a pollution gradient in the North Sea. (1992). Marine Ecology Progress Series. 91: 215-220.
McFadzen, I. and S. Utting, The viability and growth of cryopreserved bivalve larvae. World Aquacult. T-13 (1990), p. 65.
D.R. Dixon., I.R.B. McFadzen (1987). Heterochromatin in the interphase nuclei of the common mussel Mytilus edulis L. Journal of Experimental Marine Biology and Ecology, 112, Issue 1, 1-9
Dixon, D. R. and I. McFadzen (1987). "Bis(Tributyltin) Oxide (TBTO), an antifouling compound, promotes SCE induction in the larvae of the common mussel, Mytilus edulis" Mutagenesis 2(4): 312-312
D.R. Dixon, I.R.B. McFadzen., K. Sisley (1986). Heterochromatic marker regions (nucleolar organisers) in the chromosomes of the common mussel, Mytilus edulis (Mollusca : Pelecypoda). Journal of Experimental Marine Biology and Ecology,97, Issue 2, 205-212
