Peninsula Clinical Trials Unit: publications

Results and Protocol publications
Advanced Clinical practitioner
Doctor checks the health of the liver of the patient. Image courtesy of GettyImages

2024

2023
The potential for medicinal cannabis to help manage challenging behaviour in people with intellectual disability: A perspective review – Sage Journals – November 2023
Around 2% of the population have intellectual disabilities. Over one-third people with intellectual disabilities (PwID) present with ‘challenging behaviour’, which nosologically and diagnostically is an abstract concept.
The Myriad Study – Journal of the American Academy of Child & Adolescent Psychiatry – October 2023
Student- and School-Level Factors Associated With Mental Health and Well-Being in Early Adolescence
Treatment of age-related macular degeneration with aflibercept using a treat, extend and fixed protocol; A 4-year study of treatment outcomes, durability, safety and quality of life – Acta Ophthalmologica Journal – September 2023
The aim of this study was to provide outcomes, safety, durability and quality-of-life data with aflibercept using a modified treat, extend and fixed regime over 4 years.
A pilot examination of the validity of stylus and finger drawing on visuomotor-mediated tests on ACEmobile – Journal of Clinical and Experimental Neuropsychology – August 2023
The current study sought to test whether administering visuospatial and writing tests using a tablet (finger or stylus drawing), would demonstrate equivalence to traditional pencil and paper administration on ACEmobile.
The DIADS Study – International Journal of Environmental Research and Public Health – January 2023
Comparison of Diagnostic Profiles of Deaf and Hearing Children with a Diagnosis of Autism

2022
The e-coachER Study – International Journal of Behavioral Nutrition and Physical Activity – September 2022
A process evaluation, with mediation analysis, of a web-based intervention to augment primary care exercise referral schemes: the e-coachER randomised controlled trial
The PD Stat Study – Journal of Parkinson's Disease – July 2022
Enhancing Trial Delivery in Parkinson’s Disease: Qualitative Insights from PD STAT

2021
Health risk behaviours among people with severe mental ill health during the COVID-19 pandemic – PLOS One – October 2021
Analysis of linked cohort data
The ADIR-Deaf Adaptation and the ADOS-2 Deaf Adaptation – Journal of Clinical Medicine – September 2021
Diagnosing Autism Spectrum Disorders in Deaf Children Using Two Standardised Assessment Instruments: The ADIR-Deaf Adaptation and the ADOS-2 Deaf Adaptation
A mixed-method feasibility study of a novel transitional regime of incremental haemodialysis – Clinical and Experimental Nephrology – June 2021
Study design and protocol
The ADOS-2 Study – Journal of Autism and Developmental Disorders – March 2021
Adapting and validating the Autism Diagnostic Observation Schedule Version 2 for use with deaf children and young people
The EXPRESS Study – Annals of Clinical Biochemistry – February 2021
Evaluation of the MP Rapid 2019-NCOV IgM/IgG Combo POCT test vs an established platform-based method
The SARS-CoV-2 Study – Clinical Medicine Journal – January 2021
Review of hygiene adaptations among UK doctors in controlling the spread of SARS-CoV-2 infection

2020

2010 – 2019
The TACIT Study – Clinical Interventions in Aging – November 2019
Randomised Controlled Trial Of The Effect Of Tai Chi On Postural Balance Of People With Dementia
The Sorafenib Study – Journal of Neurology, Neurosurgery & Psychiatry – February 2019
Phase 0 trial investigating the intratumoural concentration and activity of sorafenib in neurofibromatosis type 2
The REACH-HF Trial – Chronic Illness – December 2015
Needs of caregivers in heart failure management: A qualitative study

This unit receives National Institute for Health and Care Research CTU Support Funding. This funding has been awarded to support the unit in developing and supporting NIHR trials.