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John Moody

 

Personal photograph uploaded by John Moody

John Moody

  • Job title: Associate Professor (Senior Lecturer) in Biochemistry, School of Biological Sciences (Faculty of Science & Environment)
  • Telephone: +441752584640
  • Facsimile: +44 (0)1752 232970
  • Email: J.Moody@plymouth.ac.uk


Qualifications & background

B.Sc. (1st class Hons) Biochemistry, Queen's University, Belfast, 1981

Ph.D. Biology, University of York, 1984

 

Professional membership

 



Research interests

Oxidative stress including:
Effects of oxygen in promoting wound healing

Mechanisms of carbon monoxide toxicity

Mechanisms of oxygen toxicity in ciliated trachea

Interaction of oxygen-dependent host defences and antibiotic-resistant pathogens

Mitochondrial and prokaryotic electron transfer complexes

Filamentous gliding bacteria: mechanism of (UV-A+oxygen)- induced killing

Member of School of Biological Sciences Ecotoxicology and Stress Biology Research Centre
Member of Peninsula Medical School Anaethesiology Research Group

Member of Peninsula Oxidative Stress Research Forum


Ph.D. students
as Director of Studies
Lindsey Glew
Anwar Almzaiel
Hanady Al-Shmgani
Angela Cooper
Husam Aljwaid
Rebekah Simpson

as other supervisor
Faculty of Science
Zainab Al-Abady
Louise Belfield
Dokuboba Amachree
Claudio Saez Avaria
Lee Hutt

 

Other research
Yuan, J., Moody, A.J., Smerdon, G. & Handy, R.D. (2006) Hyperbaric oxygen protects endothelial cells against H2O2-induced DNA damage, Biochem. Soc. Trans.
Rankin, H.V., Moate, R.M., Moody, A.J., MacNaughton, P. & Sneyd, J.R. (2006) Uneven cilial distribution in rat trachea, British Journal of Anaesthesia 96, 281P
Rankin, H.V., Moate, R.M., Moody, A.J., MacNaughton, P., Rahamim, J., Smith, M.E.F. & Sneyd, J.R. (2006) Organ culture of human bronchial explants, British Journal of Anaesthesia 96, 281P-282P
Shaw, F.L., Handy, R.D., Bryson, P., Sneyd R. & Moody, A.J. (2004) Hyperbaric oxygen therapy does not cause oxidative stress in isolated platelets: no effect on superoxide dismutase, catalase, or cellular ATP, Journal of Physiology, PC97, 557P
Shaw, F.L., Handy, R.D., Bryson, P., Sneyd, R. & Moody, A.J. (2004) Hyperbaric oxygen therapy does not cause oxidative stress in isolated platelets: no effect on superoxide dismutase, catalase, or cellular ATP, Comparative Biochemistry and Physiology 137, S15
Handy, R.D., Moody, A.J., Bryson, P., Handy, L.M. & Sneyd, R. (2001) The effect of multiple hyperbaric oxygen treatments on blood function and redox status, Biochem. Soc. Trans. 30: abstract 31
Patel, A., Moody, A.J., Handy, R.D. & Sneyd, R. (2001) Carbon monoxide toxicity in the heart: evidence for ischaemia/reperfusion like injury, Biochem. Soc. Trans. 30: abstract 32
Patel, A.P., Moody, A.J., Handy, R.D. and Sneyd, J.R. (2000) Myoglobin as a biomarker of mitochondrial damage, Toxicology Letters 116 (Suppl. 1), 78  


Journals
Articles
Amachree D, Moody AJ & Handy RD  (2013)  'Comparison of intermittent and continuous exposures to cadmium in the blue mussel, Mytilus edulis: accumulation and sub-lethal physiological effects' Ecotoxicol Environ Saf  95,  pp 19 - 26  Author Site , DOI 
Almzaiel AJ, Billington R, Smerdon G & Moody AJ  (2013)  'Effects of hyperbaric oxygen treatment on antimicrobial function and apoptosis of differentiated HL-60 (neutrophil-like) cells' Life Sci  93  (2-3),  pp 125 - 131  Author Site , DOI 
Al-Shmgani HS, Moate RM, Macnaughton PD, Sneyd JR & Moody AJ  (2013)  'Effects of hyperoxia on the permeability of 16HBE14o- cell monolayers--the protective role of antioxidant vitamins E and C' FEBS J  280  (18),  pp 4512 - 4521  Author Site , DOI 
Melatunan S, Calosi P, Rundle SD, Widdicombe S & Moody AJ  (2013)  'Effects of ocean acidification and elevated temperature on shell plasticity and its energetic basis in an intertidal gastropod' MARINE ECOLOGY PROGRESS SERIES  472,  pp 155 - 168  Author Site , DOI 
Ahmed AR, Moody AJ, Fisher A & Davies SJ  (2013)  'Growth performance and starch utilization in common carp (Cyprinus carpio L.) in response to dietary chromium chloride supplementation' J Trace Elem Med Biol  27  (1),  pp 45 - 51  Author Site , DOI 
Al-Shmgani HS, Moate RM, Sneyd JR, Macnaughton PD & Moody AJ  (2012)  'Hyperoxia-induced ciliary loss and oxidative damage in an in vitro bovine model: the protective role of antioxidant vitamins E and C' Biochem Biophys Res Commun  429  (3-4),  pp 191 - 196  Author Site , DOI 
Al-Subiai SN, Arlt VM, Frickers PE, Readman JW, Stolpe B, Lead JR, Moody AJ & Jha AN  (2012)  'Merging nano-genotoxicology with eco-genotoxicology: an integrated approach to determine interactive genotoxic and sub-lethal toxic effects of C(60) fullerenes and fluoranthene in marine mussels, Mytilus sp' Mutat Res  745  (1-2),  pp 92 - 103  Author Site , DOI 
Nisr RB, Moody AJ & Gilpin ML  (2012)  'Screening microorganisms for insulin binding reveals binding by Burkholderia multivorans and Burkholderia cenocepacia and novel attachment of insulin to Aeromonas salmonicida via the A-layer' FEMS Microbiol Lett  328  (2),  pp 93 - 99  Author Site , DOI 
Al-Subiai SN, Moody AJ, Mustafa SA & Jha AN  (2011)  'A multiple biomarker approach to investigate the effects of copper on the marine bivalve mollusc, Mytilus edulis' Ecotoxicol Environ Saf  74  (7),  pp 1913 - 1920  Author Site , DOI 
Askar KA, Kudi AC & Moody AJ  (2011)  'Comparative analysis of cholinesterase activities in food animals using modified Ellman and Michel assays' Can J Vet Res  75  (4),  pp 261 - 270  Author Site
Askar KA, Kudi AC & Moody AJ  (2011)  'Comparison of two storage methods for the analysis of cholinesterase activities in food animals' Enzyme Res  2010,  p 904249  Author Site , DOI 
Nisr RB, Russell MA, Chrachri A, Moody AJ & Gilpin ML  (2011)  'Effects of the microbial secondary metabolites pyrrolnitrin, phenazine and patulin on INS-1 rat pancreatic β-cells' FEMS Immunol Med Microbiol  63  (2),  pp 217 - 227  Author Site , DOI 
Melatunan S, Calosi P, Rundle SD, Moody AJ & Widdicombe S  (2011)  'Exposure to elevated temperature and Pco(2) reduces respiration rate and energy status in the periwinkle Littorina littorea' Physiol Biochem Zool  84  (6),  pp 583 - 594  Author Site , DOI 
Yuan J, Handy RD, Moody AJ, Smerdon G & Bryson P  (2011)  'Limited DNA damage in human endothelial cells after hyperbaric oxygen treatment and protection from subsequent hydrogen peroxide exposure' Biochim Biophys Acta  1810  (5),  pp 526 - 531  Author Site , DOI 
Askar KA, Kudi AC & Moody AJ  (2011)  'Purification of soluble acetylcholinesterase from sheep liver by affinity chromatography' Appl Biochem Biotechnol  165  (1),  pp 336 - 346  Author Site , DOI 
Trevisan R, Mello DF, Fisher AS, Schuwerack PM, Dafre AL & Moody AJ  (2011)  'Selenium in water enhances antioxidant defenses and protects against copper-induced DNA damage in the blue mussel Mytilus edulis' Aquat Toxicol  101  (1),  pp 64 - 71  Author Site , DOI 
Askar KA, Kudi AC & Moody AJ  (2011)  'Spontaneous reactivation and aging kinetics of acetylcholinesterase inhibited by dichlorvos and diazinon' JOURNAL OF TOXICOLOGICAL SCIENCES  36  (2),  pp 237 - 241  Author Site
Waines PL, Moate R, Moody AJ, Allen M & Bradley G  (2011)  'The effect of material choice on biofilm formation in a model warm water distribution system' Biofouling  27  (10),  pp 1161 - 1174  Author Site , DOI 
Jaeschke BC, Millward GE, Moody AJ & Jha AN  (2011)  'Tissue-specific incorporation and genotoxicity of different forms of tritium in the marine mussel, Mytilus edulis' Environ Pollut  159  (1),  pp 274 - 280  Author Site , DOI 
Dallas LJ, Shultz AD, Moody AJ, Sloman KA & Danylchuk AJ  (2010)  'Chemical excretions of angled bonefish Albula vulpes and their potential use as predation cues by juvenile lemon sharks Negaprion brevirostris' J Fish Biol  77  (4),  pp 947 - 962  Author Site , DOI 
Hannam ML, Bamber SD, Galloway TS, John Moody A & Jones MB  (2010)  'Functional immune response in Pecten maximus: combined effects of a pathogen-associated molecular pattern and PAH exposure' Fish Shellfish Immunol  28  (1),  pp 249 - 252  Author Site , DOI 
Hannam ML, Bamber SD, Moody AJ, Galloway TS & Jones MB  (2010)  'Immunotoxicity and oxidative stress in the Arctic scallop Chlamys islandica: effects of acute oil exposure' Ecotoxicol Environ Saf  73  (6),  pp 1440 - 1448  Author Site , DOI 
Al-Subiai SN, Jha AN & Moody AJ  (2009)  'Contamination of bivalve haemolymph samples by adductor muscle components: implications for biomarker studies' Ecotoxicology  18  (3),  pp 334 - 342  Author Site , DOI 
Yuan J, Handy R, Moody J & Bryson P  (2006)  'Hyperbaric oxygen therapy does not stimulate production of detectable nitric oxide (NO), vascular endothelial growth factor (VEGF), or damage blood vessels in vitro' Comparative Biochemistry and Physiology A-Molecular & Integrative Physiology  143  (4),  pp S107 - S107
Moody AJ & Shaw FL  (2006)  'Reevaluation of the Greiss reaction: How much of a problem is interference by nicotinamide nucleotides?' Analytical Biochemistry  356  (1),  pp 154 - 156 , DOI 
Biggs LF & Moody AJ  (2003)  'Extreme UV-A sensitivity of the filamentous gliding bacterium Vitreoscilla stercoraria' FEMS Microbiol Lett  224  (1),  pp 73 - 76  Author Site
Brown S, Meunier B, Rumbley JN, Lemaire C, Moody AJ, Lemarre P, Blaiseau PL, Madgwick SA, Netter P & Gennis RB  (1993)  'CO recombination as a probe of the Fe/Cu binuclear centre of terminal protonmotive oxidases' Biochem Soc Trans  21  (4),  p 344S  Author Site
Chapters
Rich PR & Moody AJ  (1997)  'Cytochrome c oxidase' in Gräber P; Milazzo G (ed.)  Bioenergetics  Birkhauser  pp 418 - 456
Conference Papers
Nisr RB, Moody AJ & Gilpin ML  (2011)  'Molecular mimicries of linear epitopes between pancreatic glutamic acid decarboxylase (GAD65) and proteins from Escherichia coli' pp 140 - 140
Patel A, Moody AJ, Handy RD & Sneyd R  (2001)  'Carbon monoxide toxicity in the heart: evidence for ischaemia/reperfusion like injury. Joint meeting of the Biochemical Society and Physiological Society' p 1
Handy RD, Moody AJ, Bryson P, Handy LM & Sneyd R  (2001)  'The effect of multiple hyperbaric oxygen treatments on blood function and redox status. Joint meeting of the Biochemical Society and Physiological Society' p 1

Conferences organised

Joint organiser of Biochemical Society Bioenergetics Group Colloquium: Superoxide: production and destruction, University of Essex, July 2003

Joint organiser of 56th Harden Conference: Biological electron and proton transfer, University of Plymouth, August 2003