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John Moody![]() John Moody
Qualifications & background B.Sc. (1st class Hons) Biochemistry, Queen's University, Belfast, 1981 Ph.D. Biology, University of York, 1984 Professional membership
Research interests
Oxidative stress including: Mechanisms of carbon monoxide toxicity Mechanisms of oxygen toxicity in ciliated trachea Interaction of oxygen-dependent host defences and antibiotic-resistant pathogens Mitochondrial and prokaryotic electron transfer complexes Filamentous gliding bacteria: mechanism of (UV-A+oxygen)- induced killing Member of School of Biological Sciences Ecotoxicology and Stress Biology Research Centre Member of Peninsula Oxidative Stress Research Forum
Other research
Journals
Articles
(2013)
'Growth performance and starch utilization in common carp (Cyprinus carpio L.) in response to dietary chromium chloride supplementation.'
J Trace Elem Med Biol
27
(1),
pp 45 - 51
, DOI
(2012)
'Hyperoxia-induced ciliary loss and oxidative damage in an in vitro bovine model: the protective role of antioxidant vitamins E and C.'
Biochem Biophys Res Commun
429
(3-4),
pp 191 - 196
, DOI
(2012)
'Merging nano-genotoxicology with eco-genotoxicology: an integrated approach to determine interactive genotoxic and sub-lethal toxic effects of C(60) fullerenes and fluoranthene in marine mussels, Mytilus sp.'
Mutat Res
745
(1-2),
pp 92 - 103
, DOI
(2012)
'Screening microorganisms for insulin binding reveals binding by Burkholderia multivorans and Burkholderia cenocepacia and novel attachment of insulin to Aeromonas salmonicida via the A-layer.'
FEMS Microbiol Lett
328
(2),
pp 93 - 99
, DOI
(2011)
'A multiple biomarker approach to investigate the effects of copper on the marine bivalve mollusc, Mytilus edulis.'
Ecotoxicol Environ Saf
74
(7),
pp 1913 - 1920
, DOI
(2011)
'Comparative analysis of cholinesterase activities in food animals using modified Ellman and Michel assays.'
Can J Vet Res
75
(4),
pp 261 - 270
(2011)
'Comparison of two storage methods for the analysis of cholinesterase activities in food animals.'
Enzyme Res
2010,
p 904249
, DOI
(2011)
'Effects of the microbial secondary metabolites pyrrolnitrin, phenazine and patulin on INS-1 rat pancreatic β-cells.'
FEMS Immunol Med Microbiol
63
(2),
pp 217 - 227
, DOI
(2011)
'Exposure to elevated temperature and Pco(2) reduces respiration rate and energy status in the periwinkle Littorina littorea.'
Physiol Biochem Zool
84
(6),
pp 583 - 594
, DOI
(2011)
'Limited DNA damage in human endothelial cells after hyperbaric oxygen treatment and protection from subsequent hydrogen peroxide exposure.'
Biochim Biophys Acta
1810
(5),
pp 526 - 531
, DOI
(2011)
'Purification of soluble acetylcholinesterase from sheep liver by affinity chromatography.'
Appl Biochem Biotechnol
165
(1),
pp 336 - 346
, DOI
(2011)
'Selenium in water enhances antioxidant defenses and protects against copper-induced DNA damage in the blue mussel Mytilus edulis.'
Aquat Toxicol
101
(1),
pp 64 - 71
, DOI
(2011)
'Spontaneous reactivation and aging kinetics of acetylcholinesterase inhibited by dichlorvos and diazinon'
JOURNAL OF TOXICOLOGICAL SCIENCES
36
(2),
pp 237 - 241
(2011)
'The effect of material choice on biofilm formation in a model warm water distribution system.'
Biofouling
27
(10),
pp 1161 - 1174
, DOI
(2011)
'Tissue-specific incorporation and genotoxicity of different forms of tritium in the marine mussel, Mytilus edulis.'
Environ Pollut
159
(1),
pp 274 - 280
, DOI
(2010)
'Chemical excretions of angled bonefish Albula vulpes and their potential use as predation cues by juvenile lemon sharks Negaprion brevirostris.'
J Fish Biol
77
(4),
pp 947 - 962
, DOI
(2010)
'Effects of the model PAH phenanthrene on immune function and oxidative stress in the haemolymph of the temperate scallop Pecten maximus.'
Chemosphere
78
(7),
pp 779 - 784
, DOI
(2010)
'Functional immune response in Pecten maximus: combined effects of a pathogen-associated molecular pattern and PAH exposure.'
Fish Shellfish Immunol
28
(1),
pp 249 - 252
, DOI
(2010)
'Immunotoxicity and oxidative stress in the Arctic scallop Chlamys islandica: effects of acute oil exposure.'
Ecotoxicol Environ Saf
73
(6),
pp 1440 - 1448
, DOI
(2009)
'Contamination of bivalve haemolymph samples by adductor muscle components: implications for biomarker studies.'
Ecotoxicology
18
(3),
pp 334 - 342
, DOI
(2009)
'Hyperbaric oxygen treatment induces platelet aggregation and protein release, without altering expression of activation molecules.'
Clin Biochem
42
(6),
pp 467 - 476
, DOI
(2009)
'Immune function in the Arctic Scallop, Chlamys islandica, following dispersed oil exposure.'
Aquat Toxicol
92
(3),
pp 187 - 194
, DOI
(2009)
'Response of blood vessels in vitro to hyperbaric oxygen (HBO): modulation of VEGF and NO(x) release by external lactate or arginine.'
Biochim Biophys Acta
1787
(7),
pp 828 - 834
, DOI
(2008)
'Defences against oxidative stress in vibrios associated with corals.'
FEMS Microbiol Lett
281
(1),
pp 58 - 63
, DOI
(2007)
'An enzyme in snail saliva induces herbivore-resistance in a marine alga'
FUNCTIONAL ECOLOGY
21
(1),
pp 101 - 106
, DOI
(2007)
'Elevated oxygen fraction reduces cilial abundance in explanted human bronchial tissue.'
Ultrastruct Pathol
31
(5),
pp 339 - 346
, DOI
(2007)
'Herbivore-induced infochemicals influence foraging behaviour in two intertidal predators.'
Oecologia
151
(3),
pp 454 - 463
, DOI
(2007)
'Protective effects of selenium on mercury-induced DNA damage in mussel haemocytes.'
Aquat Toxicol
84
(1),
pp 11 - 18
, DOI
(2006)
'Hyperbaric oxygen therapy does not stimulate production of detectable nitric oxide (NO), vascular endothelial growth factor (VEGF), or damage blood vessels in vitro'
Comparative Biochemistry and Physiology A-Molecular & Integrative Physiology
143
(4),
pp S107 - S107
(2006)
'Reevaluation of the Greiss reaction: How much of a problem is interference by nicotinamide nucleotides?'
Analytical Biochemistry
356
(1),
pp 154 - 156
, DOI
(2005)
'A single exposure to hyperbaric oxygen does not cause oxidative stress in isolated platelets: no effect on superoxide dismutase, catalase, or cellular ATP.'
Clin Biochem
38
(8),
pp 722 - 726
, DOI
(2005)
'Oxidative metabolism in platelets, platelet aggregation, and hematology in patients undergoing multiple hyperbaric oxygen exposures.'
Undersea Hyperb Med
32
(5),
pp 327 - 340
(2004)
'Carbon monoxide exposure in rat heart: evidence for two modes of toxicity.'
Biochem Biophys Res Commun
321
(1),
pp 241 - 246
, DOI
(2003)
'Carbon monoxide exposure in rat heart: glutathione depletion is prevented by antioxidants.'
Biochem Biophys Res Commun
302
(2),
pp 392 - 396
(2003)
'Extreme UV-A sensitivity of the filamentous gliding bacterium Vitreoscilla stercoraria.'
FEMS Microbiol Lett
224
(1),
pp 73 - 76
(2003)
'The degree of carotenoid esterification influences the absorption of astaxanthin in rainbow trout, Oncorhynchus mykiss (Walbaum)'
AQUACULTURE NUTRITION
9
(4),
pp 247 - 251
, DOI
(2002)
'Effect of esterification on the absorption of astaxanthin in rainbow trout, Oncorhynchus mykiss (Walbaum)'
AQUACULTURE RESEARCH
33
(5),
pp 343 - 350
, DOI
(1998)
'The reaction of halides with pulsed cytochrome bo from Escherichia coli.'
Biochem J
331 ( Pt 2),
pp 459 - 464
(1997)
'Comparison of the ligand-binding properties of native and copper-less cytochromes bo from Escherichia coli.'
Biochem J
324 ( Pt 3),
pp 743 - 752
(1997)
'EPR spectroscopy of Escherichia coli cytochrome bo which lacks CuB.'
FEBS Lett
412
(1),
pp 43 - 47
(1997)
'The reaction of halides with cytochrome bo from Escherichia coli.'
Biochem Soc Trans
25
(1),
p 62S
(1995)
'Cyanide and carbon monoxide binding to the reduced form of cytochrome bo from Escherichia coli.'
Biochemistry
34
(23),
pp 7576 - 7585
(1995)
'Interconversion of fast and slow forms of cytochrome bo from Escherichia coli.'
Biochemistry
34
(20),
pp 6838 - 6846
(1994)
''CO2-ligated' cytochrome c oxidase: characterization and comparison with the Cl- -ligated enzyme.'
Biochem J
302 ( Pt 3),
pp 821 - 826
(1994)
'Flash photolysis of the carbon monoxide compounds of wild-type and mutant variants of cytochrome bo from Escherichia coli.'
Biochim Biophys Acta
1183
(3),
pp 521 - 532
(1994)
'The reaction of hydrogen peroxide with pulsed cytochrome bo from Escherichia coli.'
Eur J Biochem
226
(2),
pp 731 - 737
(1993)
'CO recombination as a probe of the Fe/Cu binuclear centre of terminal protonmotive oxidases.'
Biochem Soc Trans
21
(4),
p 344S
(1993)
'Cyanide binding to single-electron-reduced fast cytochrome-c oxidase.'
Biochem Soc Trans
21 ( Pt 3)
(3),
p 258S
(1993)
'Ligand-binding properties and heterogeneity of cytochrome bo from Escherichia coli.'
Biochim Biophys Acta
1141
(2-3),
pp 321 - 329
(1993)
'The effects of bicarbonate/carbon dioxide on the near-UV/visible spectrum and ligand binding properties of fast bovine heart cytochrome c oxidase.'
Biochem Soc Trans
21
(4),
p 346S
(1992)
'Detection of a near infra-red absorption band of ferrohaem a3 in cytochrome c oxidase.'
FEBS Lett
305
(3),
pp 171 - 173
(1992)
'Ligand binding properties of bacterial oxidases in relation to cytochrome-c oxidase.'
Biochem Soc Trans
20
(3),
p 240S
(1991)
'Characterisation of 'fast' and 'slow' forms of bovine heart cytochrome-c oxidase.'
Biochim Biophys Acta
1059
(2),
pp 189 - 207
(1991)
'HETEROGENEITY IN FAST CYANIDE-BINDING PREPARATIONS OF CYTOCHROME-C-OXIDASE'
BIOCHEMICAL SOCIETY TRANSACTIONS
19
(3),
pp S262 - S262
(1991)
'Single electron reduction of 'slow' and 'fast' cytochrome-c oxidase.'
FEBS Lett
293
(1-2),
pp 101 - 105
(1991)
'THE CYTOCHROME-OXIDASE G = 12 EPR SIGNAL'
BIOCHEMICAL SOCIETY TRANSACTIONS
19
(3),
pp S259 - S259
(1990)
'Inhibitor effects on redox-linked protonations of the b haems of the mitochondrial bc1 complex.'
Biochim Biophys Acta
1018
(1),
pp 29 - 40
(1990)
'The effect of pH on redox titrations of haem a in cyanide-liganded cytochrome-c oxidase: experimental and modelling studies.'
Biochim Biophys Acta
1015
(2),
pp 205 - 215
(1989)
'MITOCHONDRIAL DAMAGE AND PROTONMOTIVE STOICHIOMETRY'
BIOCHEMICAL SOCIETY TRANSACTIONS
17
(5),
pp 893 - 894
(1989)
'REDOX TITRATION OF HEME-A IN CYANIDE-LIGANDED CYTOCHROME-C OXIDASE - EFFECT OF PH'
BIOCHEMICAL SOCIETY TRANSACTIONS
17
(5),
pp 895 - 896
(1989)
'REDOX TITRATION OF HEME-A IN CYANIDE-LIGANDED CYTOCHROME-C OXIDASE - SIMULATION STUDIES ON INTERACTING, PH-DEPENDENT, REDOX CENTERS'
BIOCHEMICAL SOCIETY TRANSACTIONS
17
(5),
pp 896 - 897
(1989)
'The functional catalytic unit involved in proton pumping by rat liver cytochrome-c reductase and by cytochrome-c oxidase.'
Biochim Biophys Acta
973
(1),
pp 29 - 34
(1987)
'Protonmotive stoichiometry of rat liver cytochrome c oxidase: determination by a new rate/pulse method.'
Biochim Biophys Acta
894
(2),
pp 209 - 227
(1986)
'IDENTIFICATION OF THE NICOTINAMIDE NUCLEOTIDE TRANSHYDROGENASE OF RAT-LIVER MITOCHONDRIA'
BIOCHEMICAL SOCIETY TRANSACTIONS
14
(6),
pp 1210 - 1212
(1986)
'Is there Ca2+(Sr2+)-3-hydroxybutyrate symport in rat-liver mitochondria? A reappraisal.'
Eur J Biochem
157
(2),
pp 243 - 249
(1986)
'Measurement of the proton-motive stoichiometry of the respiratory chain of rat liver mitochondria: the effect of N-ethylmaleimide.'
Biochim Biophys Acta
849
(2),
pp 229 - 235
(1986)
'Proton translocation by cytochrome oxidase in (antimycin + myxothiazol)-treated rat liver mitochondria using ferrocyanide or hexammineruthenium as electron donor.'
Biochem J
236
(1),
pp 15 - 21
(1983)
'Inhibition of nicotinamide nucleotide transhydrogenase in rat liver submitochondrial particles by dicyclohexylcarbodi-imide and butanedione.'
Biochem J
209
(3),
pp 889 - 892
Reviews
(1996)
''As prepared' forms of fully oxidised haem/Cu terminal oxidases.'
Biochim Biophys Acta
1276
(1),
pp 6 - 20
(1993)
'Binuclear centre structure of terminal protonmotive oxidases.'
FEBS Lett
316
(3),
pp 216 - 223
(1985)
'Chemiosmotic coupling in cytochrome oxidase. Possible protonmotive O loop and O cycle mechanisms.'
FEBS Lett
188
(1),
pp 1 - 7
Chapters
(1997)
'Cytochrome c oxidase'
in Gräber P, Milazzo G (ed.)
Bioenergetics
Birkhauser
pp 418 - 456
Conference Papers
(2011)
'Molecular mimicries of linear epitopes between pancreatic glutamic acid decarboxylase (GAD65) and proteins from Escherichia coli'
pp 140 - 140
(2009)
'Does the stress associated with catch-and-release angling of bonefish (Albula vulpes) affect predation by juvenile lemon sharks (Negaprion brevirostris)?'
pp S69 - S69
, DOI
(2006)
'Organ culture of human bronchial explants'
pp 281P - 282P
(2006)
'The effect of hyperbaric oxygen on platelet S-nitrosothiol release and aggregation'
pp S115 - S115
(2006)
'Uneven cilial distribution in rat trachea'
pp 281P - 281P
(2001)
'Carbon monoxide toxicity in the heart: evidence for ischaemia/reperfusion like injury. Joint meeting of the Biochemical Society and Physiological Society'
p 1
(2001)
'The effect of multiple hyperbaric oxygen treatments on blood function and redox status. Joint meeting of the Biochemical Society and Physiological Society'
p 1
(1995)
'Rapid-scan FTIR spectroscopic studies on the photolysis and recombination of the cyanide adduct of fully reduced bovine cytochrome c oxidase.'
pp S521 - S521
(1994)
'STORAGE EFFECTS ON THE LIGAND-BINDING PROPERTIES OF BOVINE HEART CYTOCHROME-C-OXIDASE'
pp S286 - S286
(1991)
'Ligation and electronation states of cytochrome-c oxidase in relation to other oxidases and peroxidases.'
ENGLAND
pp 617 - 622
(1989)
'THE CHARGE TRANSLOCATING REACTIONS OF THE BC COMPLEXES AND CYTOCHROME-OXIDASE'
pp 7 - 19
Conferences organised Joint organiser of Biochemical Society Bioenergetics Group Colloquium: Superoxide: production and destruction, University of Essex, July 2003 Joint organiser of 56th Harden Conference: Biological electron and proton transfer, University of Plymouth, August 2003 |
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